2. Search Result
Search Result
Results for "

urate transporter

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147300
    Puliginurad

    YL-90148

    		 URAT1 Cardiovascular Disease Metabolic Disease
    Puliginurad (YL-90148) is a potent urate transporter (URAT) inhibitor. Puliginurad can be used for hyperuricemia and gout research .
    Puliginurad
  • HY-147422
    Xininurad

    XNW3009

    		 URAT1 Metabolic Disease
    Xininurad (XNW3009) is a urate transporter (URAT) inhibitor
    Xininurad
  • HY-111345
    Epaminurad

    UR-1102; URC-102

    		 OAT URAT1 Metabolic Disease Inflammation/Immunology
    Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad is a uricosuric agent. Epaminurad can be used for gout and hyperuricemia research .
    Epaminurad
  • HY-W011711
    Benzarone

    Fragivix

    		 URAT1 Oxidative Phosphorylation Apoptosis Metabolic Disease
    Benzarone (Fragivix) is an oral inhibitor of human urate transporter 1 (hURAT1) with an IC50 value of 2.8 μM, and it also acts as an uncoupler of oxidative phosphorylation. Benzarone can cause liver damage and promote cell apoptosis and necrosis. Benzarone can be used to lower serum uric acid levels and for research in vascular diseases .
    Benzarone
  • HY-159530
    Darbinuradum

    Darbinurad

    		 URAT1 Metabolic Disease
    Darbinuradum (Darbinurad) is a urate transporter inhibitor .
    Darbinuradum
  • HY-156624
    Lingdolinurad

    		URAT1 Metabolic Disease
    Lingdolinurad is urate transporter inhibitor, targeting to hURAT1.Lingdolinurad can be used for research in hyperuricemia in vitro and in vivo .
    Lingdolinurad
  • HY-111345A
    Epaminurad hydrochloride

    UR-1102 hydrochloride; URC-102 hydrochloride

    		 OAT URAT1 Metabolic Disease Inflammation/Immunology
    Epaminurad (UR-1102) hydrochloride is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad hydrochloride quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad hydrochloride is a uricosuric agent. Epaminurad hydrochloride can be used for gout and hyperuricemia research .
    Epaminurad hydrochloride
  • HY-172778
    HNW005

    		NOD-like Receptor (NLR) URAT1 Metabolic Disease Inflammation/Immunology
    HNW005 is a dual inhibitor of NLRP3 inflammasome and urate transporter 1 (URAT1). It has a KD value of 204.6 nM and an IC50 of 1.7 μM for inhibiting NLRP3 inflammasome activation, and an IC50 of 6.4 μM for inhibiting uric acid transmembrane transport. When administered at a dose of 2 mg/kg in vivo, HNW005 can achieve a uric acid reduction rate of 64.8%. It can exert anti - inflammatory, analgesic, and uric acid - lowering activities by inhibiting the activation of NLRP3 inflammasome and uric acid transmembrane transport. HNW005 can be used in the research of gouty arthritis .
    HNW005

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: