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Results for "

trophic

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

5

Peptides

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0076
    Bilobalide
    2 Publications Verification

    (-)-Bilobalide

    		 Apoptosis Autophagy Endogenous Metabolite Neurological Disease
    Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons .
    Bilobalide
  • HY-P1015
    VIP(Guinea pig)

    Vasoactive Intestinal Peptide, guinea pig

    		 PACAP Receptor Neurological Disease Metabolic Disease
    VIP Guinea pig (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function .
    VIP(Guinea pig)
  • HY-P2671
    [Leu15]-Gastrin I (human)

    		Cholecystokinin Receptor Cancer
    [Leu15]-Gastrin I (human) is a Gastrin I, human (HY-P1097) peptide hormone derivative, which is trophic for normal gastrointestinal epithelium. Gastrin stimulates growth of gastric adenocarcinoma (gastric cancer) through G-protein-coupled receptor called the cholecystokinin (CCK) or cholecystokinin-B receptors (CCK-BR) that are overexpressed in this malignancy. [Leu15]-Gastrin I (human) is promising for research of gastric cancer .
    [Leu15]-Gastrin I (human)
  • HY-P1777
    IGF-I (24-41)

    Insulin-like Growth Factor I (24-41)

    		 IGF-1R Metabolic Disease Inflammation/Immunology
    IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .
    IGF-I (24-41)
  • HY-N0076R
    Bilobalide (Standard)

    (-)-Bilobalide (Standard)

    		 Reference Standards Apoptosis Autophagy Endogenous Metabolite Neurological Disease
    Bilobalide (Standard) is the analytical standard of Bilobalide. This product is intended for research and analytical applications. Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons .
    Bilobalide (Standard)
  • HY-P1015A
    VIP(Guinea pig) TFA

    Vasoactive Intestinal Peptide, guinea pig TFA

    		 PACAP Receptor Neurological Disease Metabolic Disease
    VIP Guinea pig TFA (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function .
    VIP(Guinea pig) TFA
  • HY-402309
    IGF-1R modulator 1

    		IGF-1R EGFR Trk Receptor Neurological Disease
    IGF-1R modulator 1 (Example 5) is an IGF-1R modulator, with EC50s of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), 0.39 μM (TrkB). IGF-1R modulator 1 can be used for research of diseases characterised by impaired signalling of neurotrophins and/or other trophic factors, such as Alzheimer's disease .
    IGF-1R modulator 1
  • HY-P1777A
    IGF-I (24-41) (TFA)

    Insulin-like Growth Factor I (24-41) (TFA)

    		 IGF-1R Metabolic Disease Inflammation/Immunology
    IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .
    IGF-I (24-41) (TFA)

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