Search Result
Results for "
triterpenoid compound
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N2895
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Arjuntriterpenic acid
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Others
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Others
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Arjunic acid (Arjuntriterpenic acid) (compound 13) is a triterpenoid compound isolated from Sanguisorba officinalis L .
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- HY-N3666
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3β-Cycloeucalenol
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Others
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Others
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Cycloeucalenol is a triterpenoid compound derived from Eucalyptus microcorys .
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- HY-N4125
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3-O-Acetyldehydroeburicoic acid
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Others
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Inflammation/Immunology
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Dehydroeburicoic acid monoacetate (Compound 18) is a lanostane triterpenoid isolated from Wolfiporia cocos .
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- HY-N13161
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Others
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Others
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28-Hydroxy-12-oleanen-3-one is a triterpenoid compound that can be isolated from the fruit of the Dipteronia sinensis .
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- HY-N15225
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Others
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Others
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12β-Hydroxyganoderenic acid B (Compound 15) is the triterpenoid compound that can be isolated from Ganoderma lucidum. Some triterpenoids isolated from Ganoderma species are reported to exhibits antitumor, antimicrobial, antiviral and anti-aging activities .
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- HY-N12160
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Others
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Others
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Erythrodiol diacetate (Compound 4) is a triterpenoid compound derived from Erythrina eriotriocha stem bark .
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- HY-N8602
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Others
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Others
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Ganoderenic acid F (compound 17) is a triterpenoid that can be found in ganoderma lucidum .
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- HY-107235
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Clematoside S; Prosapogenin CP6
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Others
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Others
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Saponin CP6 is a triterpenoid compound from the roots of Clematis grata .
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- HY-N15212
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Others
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Others
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Methyl 20(21)-dehydrolucidenate A is a triterpenoid compound found in Ganoderma sinense .
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- HY-N12587
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- HY-N13106
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Others
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Others
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Camelliagenin A 22-angelate (compound 5) is a triterpenoid isolated from the bark of birch .
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- HY-N8915
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Others
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Others
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Deoxyflindissone (Compound 13) is a triterpenoid
compound. Deoxyflindissone is isolated from natural Cornus walteri
.Deoxyflindissone has significant cytotoxic activity
.
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- HY-N1822
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Others
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Others
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3-epi-Cabraleahydroxylactone (compound 3) is a triterpenoid that can be found in Aglaia angustifolia Miq .
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- HY-N2965
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- HY-N10024
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Ganolactone A
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EBV
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Infection
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Ganolactone is a triterpenoid compound. Ganolactone has a weak inhibitory effect on EBV early antigen .
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- HY-N13717
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Others
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Others
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Ganoderic acid GS-3 is a lanostane-type triterpenoid compound that can be isolated from Ganoderma sinense .
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- HY-126607
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Others
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Others
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Sericic acid (compound 7) is a triterpenoid obtained from the methanol extract of blackberry (Rubus allegheniensis Port.) fruit .
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- HY-N0140
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Ursolic acid
Maximum Cited Publications
15 Publications Verification
Prunol; Urson; Malol
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Autophagy
Endogenous Metabolite
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Cancer
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Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.
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- HY-134960
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- HY-N4064
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Others
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Others
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Hederagenic acid (compound 2) is a kind of triterpenoid saponin. Hederagenic acid can be isolated from the roots of Kalopanax septemlobus (Thunb.) Koidz .
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- HY-N9319
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Decaisoside E
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Others
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Others
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Fulvotomentoside A (Decaisoside E) is a triterpenoid saponin compound isolated from the flowers of Lonicera fulvotomentosa Hsu et S.C. Cheng .
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- HY-N3303
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Others
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Others
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Meliasenin B (compound 2) is an apotirucallane-type triterpenoid. Meliasenin B is a nature product that could be isolated from the fruits of Melia azedarach .
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- HY-N0892
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- HY-N3500
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- HY-N15220
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Endogenous Metabolite
Phosphatase
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Cancer
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Dipsacus saponin X (compound 7) is a triterpenoid saponin that stimulates the proliferation of UMR106 cells and increases alkaline phosphatase activity in UMR106 cells (4 μM) .
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- HY-N15231
-
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Endogenous Metabolite
Phosphatase
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Cancer
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Dipsacus saponin XII (compound 6) is a triterpenoid saponin that stimulates the proliferation of UMR106 cells and increases alkaline phosphatase activity in UMR106 cells (4 μM) .
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- HY-N7640
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Others
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Inflammation/Immunology
Cancer
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Desoxylimonin is an orally active triterpenoid compound found from grapefruit seed. Desoxylimonin shows anti-proliferative activities to breast cancer cells. Desoxylimonin derivatives shows better anticancer, analgesic and anti-inflammatory activity than the lead compound .
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- HY-N10071
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Others
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Cancer
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Poricoic acid G is a triterpenoid that can be isolated from Poria cocos. Poricoic acid G has a significant cytotoxic effect on leukemia cells and is a potential potent anti-leukemic compound in humans .
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- HY-N8676
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Others
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Cancer
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Antiproliferative agent-29 (Compound 16) is a triterpenoid isolated from the seeds of Peganum harmala L. Antiproliferative agent-29 has antiproliferative activity and has potential for cancer research .
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- HY-N8152
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- HY-N8677
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Others
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Cancer
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Antiproliferative agent-28 (Compound 14) is a triterpenoid isolated from the seeds of Peganum harmala L. Antiproliferative agent-28 has antiproliferative activity and has potential for cancer research .
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- HY-N0332
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- HY-B2114
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Escin
2 Publications Verification
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Apoptosis
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Metabolic Disease
Inflammation/Immunology
Cancer
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Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent .
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- HY-N15216
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Cytochrome P450
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Metabolic Disease
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Ganolucidic acid B is a triterpenoid compound found in Ganoderma sinense. Ganolucidic acid B can activate hPXR-mediated CYP3A4 expression. Ganolucidic acid B can be used in metabolism-related research .
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- HY-N0140R
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Prunol (Standard); Urson (Standard); Malol (Standard)
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Reference Standards
Autophagy
Endogenous Metabolite
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Cancer
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Ursolic acid (Standard) is the analytical standard of Ursolic acid. This product is intended for research and analytical applications. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.
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- HY-N9345
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Others
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Others
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(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid with lupane, oleanane, and ursane skeleton .
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- HY-N9304
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19a-Hydroxyferna-7,9(11)-diene
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Others
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Others
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Fern-7-en-19α-ol (9a-Hydroxyferna-7,9(11)-diene) is a triterpenoid compound isolated from Adiantum caudatum .
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- HY-169479
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Drug Derivative
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Infection
Cancer
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Betulinic glycine amide (compound 5a) is a pentacyclic triterpenoid and derivative of Betulinic acid (HY-10529). Betulinic glycine amide has been used as a precursor in the synthesis of betulinic acid derivatives with anticancer and antiviral activity .
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- HY-N1178
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Interleukin Related
LXR
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Inflammation/Immunology
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Taraxasterol is a pentacyclic triterpenoid compound isolated from Taraxacum mongolicum. Taraxasterol is an LXRα activator, with metabolic and anti-inflammatory effects. Taraxasterol may be used in research on immune-inflammatory diseases .
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- HY-N0587
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- HY-N3188
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Akt
NF-κB
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Infection
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Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways .
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- HY-N13115A
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(E)-21-Angeloyl-protoaescigenin
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Others
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Cancer
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Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively .
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- HY-N13115
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(Z)-Protoescigenin 21-tiglate
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Others
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Cancer
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21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively .
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- HY-N0892R
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- HY-N12159
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Apoptosis
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Others
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Uvaol diacetate (Compound 5) is a triterpenoid derived from the leaves of Nerium oleunder L. and is an analog of Uvaol (HY-N1109). Uvaol has protective effects against DNA damage and can also induce apoptosis in cancer cells .
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- HY-N12846
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Others
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Metabolic Disease
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Neokadsuranic acid A is a cholesterol biosynthesis inhibitor that reduces the activity of cholesterol. Neokadsuranic acid A is a triterpenoid compound that can be isolated from Kadsura heteroclita, a plant of the Schisandraceae family. Neokadsuranic acid A can be used to study the cholesterol biosynthesis pathway and its role in traditional medicine .
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- HY-N3242
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- HY-N4063
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FXR
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Inflammation/Immunology
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Hedragonic acid is an oleane-type triterpenoid compound, which can be isolated from the stems and roots of the southern snake vine. Hedragonic acid is a ligand and agonist for FXR. Hedragonic acid protected mice from liver damage caused by acetaminophen overdose and reduced liver inflammation .
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- HY-N15221
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NO Synthase
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Inflammation/Immunology
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12-Acetoxyganoderic acid D is a triterpenoid compound found in Ganoderma sinense. 12-Acetoxyganoderic acid D exhibits certain anti-inflammatory activity and inhibits NO production in LPS (HY-D1056) stimulated RAW 264.7 macrophages .
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- HY-126462
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Bacterial
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Infection
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Lantic acid is a triterpenoid compound possessing antimicrobial activity. Lantic acid exhibits inhibitory effects on a broad range of both Gram-positive and Gram-negative bacteria, with particular potency against Escherichia coli and Bacillus subtilis. Lantic acid is utilized in the research and development of antimicrobial agents .
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- HY-126662
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Antibiotic
Bacterial
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Infection
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Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .
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- HY-N15294
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HIV
HIV Protease
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Infection
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3β-Hydroxy-27-p-Z-coumaroyloxyurs-12-en-28-oic acid (compound 8) is a triterpenoid ester HIV-1 protease inhibitor with the potential for use in the antiretroviral combination therapy of AIDS .
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- HY-N2815
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Acetylursolic acid; 3-Acetylursolic acid
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Parasite
HSP
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Infection
Cancer
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Ursolic acid acetate (Acetylursolic acid) is a triterpenoid compound and an inhibitor of Plasmodium falciparum heat shock protein 90 (PfHsp90) with a KD of 8.16 μM. Ursolic acid acetate is cytotoxic to KB cells, with an IC50 value of 8.4 μM. Ursolic acid acetate can be used in tumor and antimalarial research .
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- HY-W782762
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Endogenous Metabolite
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Metabolic Disease
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Dihydro FF-MAS is a steroid triterpenoid compound. Dihydro FF-MAS is an intermediate in the cholesterol synthesis pathway. Dihydro FF-MAS triggers the resumption of meiosis in cultured mouse oocytes in vitro, but not in vivo. Dihydro FF-MAS can be used in studies of reproduction and lipid metabolism .
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- HY-N0611
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α-Boswellic acid
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Others
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Neurological Disease
Inflammation/Immunology
Cancer
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alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .
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- HY-N8987
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Others
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Others
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(3β,7β)-3,7,23,24-Tetrahydroxycucurbita-5,25-dien-19-al (compound 3) is a cucurbitane-type triterpenoid isolated from the vines and leaves of Momordica charantia .
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- HY-N12137
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Others
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Cancer
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Glycoside St-J (Compound 2) is a triterpenoid saponin. Glycoside St-J has antitumor activity and inhibits HeLa cell proliferation. Glycoside St-J Isolates from natural Anemone flaccida. Glycoside St-J can be used in the development of new anticancer agents .
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- HY-N1178R
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Others
Interleukin Related
LXR
Reference Standards
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Inflammation/Immunology
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Taraxasterol (Standard) is the analytical standard of Taraxasterol. This product is intended for research and analytical applications. Taraxasterol is a pentacyclic triterpenoid compound isolated from Taraxacum mongolicum. Taraxasterol is an LXRα activator, with metabolic and anti-inflammatory effects. Taraxasterol may be used in research on immune-inflammatory diseases .
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- HY-N0332R
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Reference Standards
Reactive Oxygen Species (ROS)
Apoptosis
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Inflammation/Immunology
Cancer
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Ziyuglycoside II (Standard) is the analytical standard of Ziyuglycoside II. This product is intended for research and analytical applications. Ziyuglycoside II is a triterpenoid saponin compound extracted from Sanguisorba officinalis L.. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. Anti-inflammation and anti-cancer effect .
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- HY-N15719
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Others
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Others
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Dipsacus saponin R (Compound 1) is an orally active triterpenoid saponin found in Radix Dipsaci. Dipsacus saponin R promotes bone formation and repair by regulating osteoblast activity or inhibiting osteoclast function. Dipsacus saponin R is promising for research of bone diseases such as osteoporosis and fracture healing .
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- HY-149586
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Reactive Oxygen Species (ROS)
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Others
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ROS-IN-2 (compound 85) is a seco-lupane triterpenoid derivative. ROS-IN-2 blocks ROS production and protects mitochondria from damage by inhibiting excessive production of oxidative stressors. ROS-IN-2 can be used for myocardial ischemia/reperfusion (MI/R) injury research .
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- HY-N0587R
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- HY-N2440
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- HY-N9295
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Others
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Metabolic Disease
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3, 4-seco-4 (23),20(29) -Lupadiene-3,28-dioic acid
(Compound 5) is a triterpenoid compound. 3, 4-seco-4 (23),20(29)
-Lupadiene-3,28-dioic acid has a strong inhibitory effect on the production of
superoxide anions, and the inhibitory rate is 86.9±2.8% at 1 μM
.
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- HY-N2842
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Apoptosis
Caspase
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Metabolic Disease
Cancer
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α-Amyrin acetate is a pentacyclic triterpenoid compound with oral activity. α-Amyrin acetate can inhibit cancer cells proliferation and induce apoptosis. α-Amyrin acetate can reduce blood glucose level. α-Amyrin acetate can be used for the researches of cancer and metabolic disease, such as breast cancer and diabetes .
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- HY-N12161
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Others
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Metabolic Disease
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3-Acetyl-11-keto-ursolic acid (Compound 18) is a triterpenoid compound derived from Eriobotrya japonicaleaves. 3-Acetyl-11-keto-ursolic acid has 11B-hydroxysteroid dehydrogenase 1 (11b-HSD1) inhibitory activity. 3-Acetyl-11-keto-ursolic acid can be used for anti-diabetes research .
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- HY-N15354
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Others
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Others
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Jujubasaponin IV is a triterpenoid saponin compound found in Zizyphi Fructus. Animal studies have shown that Jujubasaponin IV possesses certain anti-ulcer activity, possibly through mechanisms such as enhancing the gastric mucosal barrier or inhibiting gastric acid secretion. Jujubasaponin IV can be used in research on digestive system diseases, particularly in the study of gastric ulcer mechanisms .
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- HY-N13164
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PI3K
Akt
Apoptosis
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Cancer
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Polygalacin D3 is a triterpenoid saponin compound that can be extracted from the roots of the balloon flower. Polygalacin D3 can inhibit the proliferation of non-small cell lung cancer (NSCLC) cell lines by blocking the PI3K/Akt pathway, and it induces cell cycle arrest and cell apoptosis .
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- HY-N13162
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Others
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Cancer
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Hemsleyadin D is a triterpenoid compound derived from Hemsleya penxianensis with antitumor activity. Its IC50 values against K562, MGC-803, U118, HepG2, A549, and MCF-7 cells are 93.9, 47.1, 25.9, 56.1, 66.3, and 67.6 μM, respectively .
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- HY-N15711
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Reactive Oxygen Species (ROS)
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Neurological Disease
Inflammation/Immunology
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Ganoleucoin R is a triterpenoid compound that can be isolated from Ganoderma leucocontextum. Ganoleucoin R exerts a protective effect against H2O2-induced oxidative damage and can promote neurite outgrowth in PC12 cells. Ganoleucoin R possesses neuroprotective and neurogenic activities, and can be used in the research of neurodegenerative diseases .
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- HY-N4294
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FXR
Insecticide
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Infection
Metabolic Disease
Inflammation/Immunology
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Arjungenin, a pentacyclic triterpenoid compound, is a FXR agonist. Arjungenin can improve insulin sensitivity by regulating the function of fat cells. Arjungenin exhibits moderate free radical scavenging activity. Arjungenin has growth inhibitory activity against the insect Spilarctia obliqua. Arjungenin has significant antiviral activity against a series of viruses such as chikungunya Virus (CHIKV) .
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- HY-N11020
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EBV
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Infection
Inflammation/Immunology
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Cabenoside D (compound 8) is a triterpenoid glycoside, which can be isolated from the methanol extract of lichen root. Cabenoside D shows anti-inflammatory activity and inhibits inflammation induced by 12-O-tetracylacyl hormone-13-acetate (TPA) in mice. Cabenoside D also inhibits TPA-induced Epstein-Barr virus (EBV) early antigen (EBV-EA) activation .
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- HY-N0611R
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α-Boswellic acid (Standard)
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Reference Standards
Others
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Neurological Disease
Inflammation/Immunology
Cancer
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alpha-Boswellic acid (Standard) is the analytical standard of alpha-Boswellic acid. This product is intended for research and analytical applications. alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .
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- HY-N15355
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Others
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Others
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Jujubasaponin VI is a triterpenoid saponin compound found in Zizyphi Fructus, exhibiting anti-ulcer activity. Animal studies have shown that it can significantly inhibit the formation of stress-induced gastric ulcers, possibly through mechanisms such as protecting the gastric mucosa and suppressing gastric acid secretion. Jujubasaponin VI can be used in research related to digestive system diseases, particularly in the areas of gastric ulcers and gastric mucosal injury .
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- HY-N2922
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Amyloid-β
NF-κB
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Neurological Disease
Inflammation/Immunology
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β-Amyrin shows effectively counteract amyloid β (Aβ)-induced impairment of long-term potentiation (LTP). β-Amyrin is a promising candidate for Alzheimer's disease (AD) research. β-Amyrin exhibits anti-inflammatory effects, protective activity against pulmonary fibrosis, and notable antibacterial capabilities. β-Amyrin is an orally active natural triterpenoid compound .
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- HY-N2922R
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Reference Standards
Amyloid-β
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Neurological Disease
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β-Amyrin shows effectively counteract amyloid β (Aβ)-induced impairment of long-term potentiation (LTP). β-Amyrin is a promising candidate for Alzheimer's disease (AD) research. β-Amyrin exhibits anti-inflammatory effects, protective activity against pulmonary fibrosis, and notable antibacterial capabilities. β-Amyrin is an orally active natural triterpenoid compound .
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- HY-N4294R
-
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Reference Standards
FXR
Insecticide
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Infection
Metabolic Disease
Inflammation/Immunology
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Arjungenin (Standard) is the analytical standard of Arjungenin. This product is intended for research and analytical applications. Arjungenin, a pentacyclic triterpenoid compound, is a FXR agonist. Arjungenin can improve insulin sensitivity by regulating the function of fat cells. Arjungenin exhibits moderate free radical scavenging activity. Arjungenin has growth inhibitory activity against the insect Spilarctia obliqua. Arjungenin has significant antiviral activity against a series of viruses such as chikungunya Virus (CHIKV).
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- HY-112671
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RTA dh404
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Keap1-Nrf2
NF-κB
Apoptosis
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Cardiovascular Disease
Inflammation/Immunology
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CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB . CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats .
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- HY-N8230
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HIV
HIV Protease
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Infection
Inflammation/Immunology
Cancer
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Ganosinensic acid C is a triterpenoid compound that can be extracted from Ganoderma lucidum. Ganosinensic acid C has important biological activities such as anti-tumor, anti-prostate cancer, anti-inflammatory, and inhibition of HIV-I protease. Ganosinensic acid C has an IC50 value of 10.5 μM against human highly metastatic lung cancer cell line 95D. Ganosinensic acid C has an IC50 value of Ganosinensic acid C against cervical cancer cell line Hela is 13.2 μM .
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- HY-172449
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Hedgehog
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Cancer
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GLI1-IN-3 (Compound 11a), a triterpenoid analogue, can inhibit Hedgehog signaling in GLI1 overexpression cancer cells. GLI1-IN-3 inhibits the proliferation in NSCLC and prostate cancer cell lines exhibiting hyper-activated Hh signaling. GLI1-IN-3 can also decrease the expression of endogenous GLI1 protein and its target genes associated with tumor progression and proliferation in A549 and DU-145 cancer cells .
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- HY-N13710
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EBV
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Infection
Cancer
|
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20-Hydroxylucidenic acid E2 is a triterpenoid compound found in Ganoderma lucidum. It exhibits significant inhibitory effects on inflammation induced by TPA (HY-18739). Additionally, 20-Hydroxylucidenic acid E2 can suppress the expression of EBV early antigen induced by TPA (HY-18739), with a IC50 of 290 mol ratio/32 pmol TPA (meaning that when the molar concentration of this compound is 290 times that of 32 pmol of TPA, it can inhibit 50% of EBV early antigen expression). Therefore, 20-Hydroxylucidenic acid E2 has potential applications in anti-inflammatory and anticancer research .
|
-
- HY-126741
-
|
|
Apoptosis
Parasite
NF-κB
Bcl-2 Family
Caspase
|
Infection
Inflammation/Immunology
Cancer
|
|
Azadirachtin is an oral active triterpenoid compound with anticancer, antimalarial, anti-inflammatory, and insecticidal activities. Azadirachtin induces cell apoptosis through the mitochondrial pathway (by inhibiting Bcl-2/Bax ratio or activating Apaf-1 and caspase-3) or through death receptors (by inhibiting TNFR activation). Additionally, Azadirachtin exerts its anti-inflammatory effects by inhibiting NF-кB signaling pathway activation, and it exhibits insecticidal activity by inducing apoptosis in insect cells .
|
-
- HY-N9284
-
|
|
Others
|
Cancer
|
|
5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol is a triterpenoid compound derived from Momordica charantia with antitumor activity, exhibiting an IC50 of 32.52 μM against U937 cells. 5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol shows promise for research in the field of cancer .
|
-
- HY-N8423
-
|
|
ERK
GSK-3
Apoptosis
Caspase
COX
|
Infection
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
α-Amyrin is a pentacyclic triterpenoid compound with oral activity. α-Amyrin activates the ERK and GSK-3β signaling pathways. α-Amyrin can inhibit cancer cells proliferation and induce apoptosis. α-Amyrin shows anti-bacterial and anti-inflammation activity. α-Amyrin can reduce blood glucose level. α-Amyrin can be used for the researches of cancer, infection, inflammation, metabolic disease and neurological disease, such as breast cancer, Streptococcus oralis infection, skin inflammation and diabetes .
|
-
- HY-N8229
-
|
|
Others
|
Inflammation/Immunology
|
|
7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid is a triterpenoid compound found in Ganoderma lucidum. 7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid may exhibit anti-inflammatory activity and holds potential for research in inflammatory diseases .
|
-
- HY-N7635
-
|
β-D-Glucopyranosyl oleanolate
|
NO Synthase
COX
Interleukin Related
Claudin
p38 MAPK
Akt
PI3K
|
Inflammation/Immunology
|
|
Oleanolic acid 28-O-β-D-glucopyranoside (β-D-Glucopyranosyl oleanolate) is an orally active pentacyclic triterpenoid compound. Oleanolic acid 28-O-β-D-glucopyranoside has anti-inflammatory effects. In ulcerative colitis models, Oleanolic acid 28-O-β-D-glucopyranoside can inhibit the inflammatory response, enhance the intestinal epithelial barrier function, and modulate the gut microbiota. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways. Oleanolic acid 28-O-β-D-glucopyranoside can be used in the research of diseases such as colitis .
|
-
- HY-N8423R
-
|
|
Reference Standards
ERK
GSK-3
Apoptosis
Caspase
COX
|
Infection
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
α-Amyrin (Standard) is a pentacyclic triterpenoid compound with oral activity. α-Amyrin (Standard) activates the ERK and GSK-3β signaling pathways. α-Amyrin (Standard) can inhibit cancer cells proliferation and induce apoptosis. α-Amyrin (Standard) shows anti-bacterial and anti-inflammation activity. α-Amyrin (Standard) can reduce blood glucose level. α-Amyrin (Standard) can be used for the researches of cancer, infection, inflammation, metabolic disease and neurological disease, such as breast cancer, Streptococcus oralis infection, skin inflammation and diabetes .
|
-
- HY-N0853
-
|
|
AMPK
Acetyl-CoA Carboxylase
PPAR
MMP
Interleukin Related
|
Infection
Cardiovascular Disease
Metabolic Disease
Cancer
|
|
Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
|
-
- HY-N0853R
-
|
|
Reference Standards
AMPK
Acetyl-CoA Carboxylase
PPAR
MMP
Interleukin Related
|
Infection
Cardiovascular Disease
Metabolic Disease
Cancer
|
|
Alisol A (Standard) is the analytical standard of Alisol A (HY-N0853). This product is intended for research and analytical applications. Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
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-
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-N0611
-
-
- HY-N8987
-
-
- HY-N12137
-
-
- HY-N1178R
-
-
- HY-N0332R
-
-
- HY-N15719
-
-
- HY-N0587R
-
-
- HY-N2440
-
-
- HY-N9295
-
-
- HY-N2842
-
-
- HY-N12161
-
-
- HY-N15354
-
|
|
Polysaccharides
Ziziphus jujuba
Source classification
Plants
Rhamnaceae
Saccharides
|
Others
|
|
Jujubasaponin IV is a triterpenoid saponin compound found in Zizyphi Fructus. Animal studies have shown that Jujubasaponin IV possesses certain anti-ulcer activity, possibly through mechanisms such as enhancing the gastric mucosal barrier or inhibiting gastric acid secretion. Jujubasaponin IV can be used in research on digestive system diseases, particularly in the study of gastric ulcer mechanisms .
|
-
- HY-N13164
-
-
- HY-N13162
-
|
|
Triterpenes
Terpenoids
Source classification
Cucurbitaceae
Plants
Hemsleya pengxianensis W. J. Chang
|
Others
|
|
Hemsleyadin D is a triterpenoid compound derived from Hemsleya penxianensis with antitumor activity. Its IC50 values against K562, MGC-803, U118, HepG2, A549, and MCF-7 cells are 93.9, 47.1, 25.9, 56.1, 66.3, and 67.6 μM, respectively .
|
-
- HY-N15711
-
|
|
Triterpenes
Microorganisms
Terpenoids
Source classification
|
Reactive Oxygen Species (ROS)
|
|
Ganoleucoin R is a triterpenoid compound that can be isolated from Ganoderma leucocontextum. Ganoleucoin R exerts a protective effect against H2O2-induced oxidative damage and can promote neurite outgrowth in PC12 cells. Ganoleucoin R possesses neuroprotective and neurogenic activities, and can be used in the research of neurodegenerative diseases .
|
-
- HY-N4294
-
-
- HY-N11020
-
-
- HY-N0611R
-
|
α-Boswellic acid (Standard)
|
Triterpenes
Terpenoids
Source classification
Boswellia serrata
Plants
Burseraceae
|
Reference Standards
Others
|
|
alpha-Boswellic acid (Standard) is the analytical standard of alpha-Boswellic acid. This product is intended for research and analytical applications. alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .
|
-
- HY-N15355
-
|
|
Polysaccharides
Ziziphus jujuba
Source classification
Plants
Rhamnaceae
Saccharides
|
Others
|
|
Jujubasaponin VI is a triterpenoid saponin compound found in Zizyphi Fructus, exhibiting anti-ulcer activity. Animal studies have shown that it can significantly inhibit the formation of stress-induced gastric ulcers, possibly through mechanisms such as protecting the gastric mucosa and suppressing gastric acid secretion. Jujubasaponin VI can be used in research related to digestive system diseases, particularly in the areas of gastric ulcers and gastric mucosal injury .
|
-
- HY-N2922
-
|
|
Monophenols
Celastrus hindsii Benth.
Celastraceae
Phenols
Plants
|
Amyloid-β
NF-κB
|
|
β-Amyrin shows effectively counteract amyloid β (Aβ)-induced impairment of long-term potentiation (LTP). β-Amyrin is a promising candidate for Alzheimer's disease (AD) research. β-Amyrin exhibits anti-inflammatory effects, protective activity against pulmonary fibrosis, and notable antibacterial capabilities. β-Amyrin is an orally active natural triterpenoid compound .
|
-
- HY-N2922R
-
|
|
Monophenols
Celastrus hindsii Benth.
Celastraceae
Phenols
Plants
|
Reference Standards
Amyloid-β
|
|
β-Amyrin shows effectively counteract amyloid β (Aβ)-induced impairment of long-term potentiation (LTP). β-Amyrin is a promising candidate for Alzheimer's disease (AD) research. β-Amyrin exhibits anti-inflammatory effects, protective activity against pulmonary fibrosis, and notable antibacterial capabilities. β-Amyrin is an orally active natural triterpenoid compound .
|
-
- HY-N4294R
-
|
|
Triterpenes
Terpenoids
Combretaceae
Source classification
Terminalia chebula Retz.
Plants
|
Reference Standards
FXR
Insecticide
|
|
Arjungenin (Standard) is the analytical standard of Arjungenin. This product is intended for research and analytical applications. Arjungenin, a pentacyclic triterpenoid compound, is a FXR agonist. Arjungenin can improve insulin sensitivity by regulating the function of fat cells. Arjungenin exhibits moderate free radical scavenging activity. Arjungenin has growth inhibitory activity against the insect Spilarctia obliqua. Arjungenin has significant antiviral activity against a series of viruses such as chikungunya Virus (CHIKV).
|
-
- HY-N8230
-
|
|
Microorganisms
Ketones, Aldehydes, Acids
Source classification
|
HIV
HIV Protease
|
|
Ganosinensic acid C is a triterpenoid compound that can be extracted from Ganoderma lucidum. Ganosinensic acid C has important biological activities such as anti-tumor, anti-prostate cancer, anti-inflammatory, and inhibition of HIV-I protease. Ganosinensic acid C has an IC50 value of 10.5 μM against human highly metastatic lung cancer cell line 95D. Ganosinensic acid C has an IC50 value of Ganosinensic acid C against cervical cancer cell line Hela is 13.2 μM .
|
-
- HY-N13710
-
|
|
Triterpenes
Microorganisms
Terpenoids
Source classification
|
EBV
|
|
20-Hydroxylucidenic acid E2 is a triterpenoid compound found in Ganoderma lucidum. It exhibits significant inhibitory effects on inflammation induced by TPA (HY-18739). Additionally, 20-Hydroxylucidenic acid E2 can suppress the expression of EBV early antigen induced by TPA (HY-18739), with a IC50 of 290 mol ratio/32 pmol TPA (meaning that when the molar concentration of this compound is 290 times that of 32 pmol of TPA, it can inhibit 50% of EBV early antigen expression). Therefore, 20-Hydroxylucidenic acid E2 has potential applications in anti-inflammatory and anticancer research .
|
-
- HY-126741
-
-
- HY-N9284
-
-
- HY-N8423
-
|
|
Triterpenes
other families
Terpenoids
Plants
|
ERK
GSK-3
Apoptosis
Caspase
COX
|
|
α-Amyrin is a pentacyclic triterpenoid compound with oral activity. α-Amyrin activates the ERK and GSK-3β signaling pathways. α-Amyrin can inhibit cancer cells proliferation and induce apoptosis. α-Amyrin shows anti-bacterial and anti-inflammation activity. α-Amyrin can reduce blood glucose level. α-Amyrin can be used for the researches of cancer, infection, inflammation, metabolic disease and neurological disease, such as breast cancer, Streptococcus oralis infection, skin inflammation and diabetes .
|
-
- HY-N8229
-
|
|
Triterpenes
Microorganisms
Terpenoids
Source classification
|
Others
|
|
7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid is a triterpenoid compound found in Ganoderma lucidum. 7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid may exhibit anti-inflammatory activity and holds potential for research in inflammatory diseases .
|
-
- HY-N7635
-
-
- HY-N8423R
-
|
|
Triterpenes
other families
Terpenoids
Plants
|
Reference Standards
ERK
GSK-3
Apoptosis
Caspase
COX
|
|
α-Amyrin (Standard) is a pentacyclic triterpenoid compound with oral activity. α-Amyrin (Standard) activates the ERK and GSK-3β signaling pathways. α-Amyrin (Standard) can inhibit cancer cells proliferation and induce apoptosis. α-Amyrin (Standard) shows anti-bacterial and anti-inflammation activity. α-Amyrin (Standard) can reduce blood glucose level. α-Amyrin (Standard) can be used for the researches of cancer, infection, inflammation, metabolic disease and neurological disease, such as breast cancer, Streptococcus oralis infection, skin inflammation and diabetes .
|
-
- HY-N0853
-
|
|
Triterpenes
Alisma plantago-aquatica Linn.
Classification of Application Fields
Terpenoids
Source classification
Other Diseases
Alismataceae
Plants
Disease Research Fields
|
AMPK
Acetyl-CoA Carboxylase
PPAR
MMP
Interleukin Related
|
|
Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
|
-
- HY-N0853R
-
|
|
Triterpenes
Alisma plantago-aquatica Linn.
Terpenoids
Source classification
Alismataceae
Plants
|
Reference Standards
AMPK
Acetyl-CoA Carboxylase
PPAR
MMP
Interleukin Related
|
|
Alisol A (Standard) is the analytical standard of Alisol A (HY-N0853). This product is intended for research and analytical applications. Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
|
-
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