Search Result
Results for "
sulfhydryl groups
" in MedChemExpress (MCE) Product Catalog:
56
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-121167
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Glutaminase
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Cancer
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L-albizziin, as a sulfhydryl group reagent, is a glutamase inhibitor. L-albizziin can be used for the research of cancer .
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- HY-Y1666
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Biochemical Assay Reagents
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Others
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2,2′-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2′-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation–reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers .
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- HY-119970
-
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NF-κB
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Inflammation/Immunology
Cancer
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Helenalin is an anti-inflammatory sesquiterpene lactone. Helenalin selectively inhibits transcription factor NF-κB by directly targeting p65. Helenalin has alkylating activity, targets the cysteine sulfhydryl groups in the p65 subunit of NF-κB, thereby inhibits its DNA binding .
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- HY-100216
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SPDP
5 Publications Verification
SPDP Crosslinker; Py-ds-Prp-OSu
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ADC Linker
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Cancer
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SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
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- HY-D1618
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Fluorescent Dye
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Others
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Cyanine3 maleimide tetrafluoroborate is a specific labeling reagent for sulfhydryl groups with the λex of 550 nm and λem of 580 nm. Cyanine3 maleimide tetrafluoroborate can be used for protein and peptide labeling .
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- HY-D1654
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Fluorescent Dye
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Others
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BDP 581/591 maleimide is a linker of the BDP 581/591 dye. It has a long fluorescence lifetime and can be used for fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5, for the labeling of sulfhydryl groups of proteins and peptides.
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- HY-W1048553C
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Biochemical Assay Reagents
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Others
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Mal-PEG-NH2 TFA (MW 5000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553H
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Biochemical Assay Reagents
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Others
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Mal-PEG-NH2 TFA (MW 40000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553A
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Biochemical Assay Reagents
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Others
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Mal-PEG-NH2 TFA (MW 2000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553B
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Biochemical Assay Reagents
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Others
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Mal-PEG-NH2 TFA (MW 3400) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553E
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Biochemical Assay Reagents
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Others
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Mal-PEG-NH2 TFA (MW 20000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553
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Biochemical Assay Reagents
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Others
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Mal-PEG-NH2 TFA (MW 1000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-W1048553D
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Biochemical Assay Reagents
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Others
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Mal-PEG-NH2 TFA (MW 10000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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- HY-128925
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AMAS
1 Publications Verification
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ADC Linker
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Cancer
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AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.
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- HY-D0975
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ADC Linker
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Cancer
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Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
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- HY-D2182
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Fluorescent Dye
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Others
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Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
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- HY-W888514
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mPEG-propionaldehyde
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Biochemical Assay Reagents
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Others
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mPEG-CHO (mPEG-propionaldehyde) is a polyethylene glycol (PEG) derivative with a propionaldehyde group. Propionaldehyde is a highly reactive functional group that can covalently bind to amino, sulfhydryl and other functional groups .
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- HY-174941
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Biochemical Assay Reagents
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Others
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Mal-PEG18-acid is a PEG derivative modified with maleimide groups. Maleimide is a functional group that can undergo Michael addition reaction with sulfhydryl (–SH) groups and can be used for bioconjugation.
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- HY-D2180
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Fluorescent Dye
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Others
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Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
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- HY-W698574
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Biochemical Assay Reagents
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Dansylamidoethyl mercaptan is a molecule that reacts with -SH groups of proteins and other sulfhydryl-containing molecules and has activity for detecting SS bonds in proteins.
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- HY-W190746
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Biochemical Assay Reagents
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Others
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Mal-PEG1-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
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- HY-W190755
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Biochemical Assay Reagents
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Others
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Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
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- HY-N7594
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O-Acetylsenecionine
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Mitochondrial Metabolism
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Others
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Senecionine acetate (O-Acetylsenecionine) is a pyrrolizidine alkaloid. Senecionine acetate inhibits the sequestration of Ca 2+ in extramitochondrial and mitochondrial compartments possibly by inactivating free sulfhydryl groups .
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- HY-126493
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Drug-Linker Conjugates for ADC
Microtubule/Tubulin
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Cancer
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DM4-SPDP is a agent-linker conjugate composed of a potent antitubulin agent DM4 and a linker SMCC to make antibody agent conjugate . SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls .
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- HY-78961
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EMCS
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ADC Linker
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Cancer
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6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates .
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- HY-141540
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Biochemical Assay Reagents
Endogenous Metabolite
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Others
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Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers .
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- HY-129655
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ADC Linker
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Cancer
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Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent which contains N-hydroxysuccinimide (NHS) ester and maleimide groups, allowing covalent conjugation of amine- and sulfhydryl-containing molecules .
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- HY-W1048555B
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Biochemical Assay Reagents
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Others
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Mal-PEG-SCM (MW 3400) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 3400) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555A
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Biochemical Assay Reagents
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Others
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Mal-PEG-SCM (MW 2000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 2000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555D
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Biochemical Assay Reagents
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Others
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Mal-PEG-SCM (MW 10000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 10000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555H
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Biochemical Assay Reagents
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Others
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Mal-PEG-SCM (MW 40000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 40000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555C
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Biochemical Assay Reagents
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Others
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Mal-PEG-SCM (MW 5000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 5000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555E
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Biochemical Assay Reagents
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Others
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Mal-PEG-SCM (MW 20000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 20000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048555
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Biochemical Assay Reagents
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Others
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Mal-PEG-SCM (MW 1000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 1000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W588728
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Biochemical Assay Reagents
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Others
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DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
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- HY-W588736
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Biochemical Assay Reagents
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Others
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DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
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- HY-D1869
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Fluorescent Dye
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Others
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800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .
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- HY-W440718C
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Biochemical Assay Reagents
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Others
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Cholesterol-PEG-Mal (MW 10000) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-W440718A
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Biochemical Assay Reagents
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Others
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Cholesterol-PEG-Mal (MW 400) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-W440718B
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Biochemical Assay Reagents
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Others
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Cholesterol-PEG-Mal (MW 600) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-174953B
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Biochemical Assay Reagents
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Others
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TPP-PEG-Mal (MW 3400) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-174953D
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Biochemical Assay Reagents
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Others
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TPP-PEG-Mal (MW 10000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-174953A
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Biochemical Assay Reagents
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Others
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TPP-PEG-Mal (MW 2000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-174953
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Biochemical Assay Reagents
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Others
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TPP-PEG-Mal (MW 1000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-129748
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Carboxylesterase (CES)
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Others
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SQ-24,798 is a compound that inhibits carboxypeptidase B with high affinity and specificity. Its inhibitory effect may be achieved through the binding of the sulfhydryl group to the zinc ion of the enzyme and specific side chains.
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- HY-174953C
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Biochemical Assay Reagents
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Others
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TPP-PEG-Mal (MW 5000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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- HY-129654
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Sodium (2-Sulfonatoethyl)methanethiosulfonate
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Biochemical Assay Reagents
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Others
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MTSES sodium (Sodium (2-Sulfonatoethyl)methanethiosulfonate) is a negatively charged, membrane-impermeable methanethiosulfonate (MTS). MTS is a compound that reacts with sulfhydryl groups to form mixed disulfide bonds and is often used to study cysteine ??residues on proteins.
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- HY-D1730
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Fluorescent Dye
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Others
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AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .
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- HY-174921
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Biochemical Assay Reagents
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Others
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Maleimide-PEG-COOH (MW 1000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
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- HY-174921B
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Biochemical Assay Reagents
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Others
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Maleimide-PEG-COOH (MW 3400) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
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- HY-174921C
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Biochemical Assay Reagents
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Others
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Maleimide-PEG-COOH (MW 5000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
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- HY-174921A
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Biochemical Assay Reagents
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Others
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Maleimide-PEG-COOH (MW 2000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
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- HY-D2094
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Fluorescent Dye
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Inflammation/Immunology
Cancer
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PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
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- HY-W1048849A
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4-Arm PEG-thiol (MW 5000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-SH (MW 5000) (4-Arm PEG-thiol (MW 5000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
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- HY-W1048849B
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4-Arm PEG-thiol (MW 10000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-SH (MW 10000) (4-Arm PEG-thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
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- HY-W1048849D
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4-Arm PEG-thiol (MW 40000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-SH (MW 40000) (4-Arm PEG-thiol (MW 40000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
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- HY-W1048849C
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4-Arm PEG-thiol (MW 20000)
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Biochemical Assay Reagents
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Others
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4-Arm PEG-SH (MW 20000) (4-Arm PEG-thiol (MW 20000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
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- HY-D2763
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Fluorescent Dye
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Others
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BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
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- HY-W879049
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DBCO-NHCO-PEG3-maleimide
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Biochemical Assay Reagents
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Others
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DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
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- HY-W879036
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Biochemical Assay Reagents
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Others
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DBCO-PEG8-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG8-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
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- HY-174961C
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Fmoc-NH-PEG-Mal (MW 5000)
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Biochemical Assay Reagents
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Others
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Fmoc-PEG-Maleimide (MW 5000) (Fmoc-NH-PEG-Mal (MW 5000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-174961B
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Fmoc-NH-PEG-Mal (MW 3400)
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Biochemical Assay Reagents
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Others
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Fmoc-PEG-Maleimide (MW 3400) (Fmoc-NH-PEG-Mal (MW 3400)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-174961
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Fmoc-NH-PEG-Mal (MW 1000)
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Biochemical Assay Reagents
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Others
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Fmoc-PEG-Maleimide (MW 1000) (Fmoc-NH-PEG-Mal (MW 1000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-174961A
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Fmoc-NH-PEG-Mal (MW 2000)
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Biochemical Assay Reagents
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Others
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Fmoc-PEG-Maleimide (MW 2000) (Fmoc-NH-PEG-Mal (MW 2000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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- HY-N6773
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HIV Protease
Fungal
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Infection
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Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives .
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- HY-174927A
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DBCO-PEG-Mal (MW 400)
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Biochemical Assay Reagents
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Others
|
|
DBCO-PEG-Maleimide (MW 400) (DBCO-PEG-Mal (MW 400)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 400) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927E
-
|
DBCO-PEG-Mal (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 3400) (DBCO-PEG-Mal (MW 3400)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 3400) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927B
-
|
DBCO-PEG-Mal (MW 600)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 600) (DBCO-PEG-Mal (MW 600)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 600) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927
-
|
DBCO-PEG-Mal (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 5000) (DBCO-PEG-Mal (MW 5000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 5000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927D
-
|
DBCO-PEG-Mal (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 2000) (DBCO-PEG-Mal (MW 2000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 2000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927C
-
|
DBCO-PEG-Mal (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Maleimide (MW 1000) (DBCO-PEG-Mal (MW 1000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 1000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-D0843S
-
|
NEM-d5
|
Cathepsin
Deubiquitinase
|
Others
|
|
N-Ethylmaleimide-d5 is the deuterium labeled N-Ethylmaleimide. N-Ethylmaleimide (NEM), a reagent that alkylates free sulfhydryl groups, is a cysteine protease inhibitor . N-ethylmaleimide specific inhibits phosphate transport in mitochondria . N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor .
|
-
- HY-D1260
-
|
PSH-red
|
Fluorescent Dye
|
Neurological Disease
|
|
FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .
|
-
- HY-167036C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG-Mal (MW 5000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 5000) can be used for drug delivery .
|
-
- HY-167036A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG-Mal (MW 1000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 1000) can be used for drug delivery .
|
-
- HY-167036D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG-Mal (MW 10000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 10000) can be used for drug delivery .
|
-
- HY-157920
-
|
N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
|
-
- HY-167036B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG-Mal (MW 3400) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 3400) can be used for drug delivery .
|
-
- HY-D1363
-
|
|
Fluorescent Dye
|
Others
|
|
BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .
|
-
- HY-D2883E
-
|
Rhodamine B-PEG-SH (MW 5000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 5000) (Rhodamine B-PEG-SH (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883B
-
|
Rhodamine B-PEG-SH (MW 1000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 1000) (Rhodamine B-PEG-SH (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883C
-
|
Rhodamine B-PEG-SH (MW 2000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 2000) (Rhodamine B-PEG-SH (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883H
-
|
Rhodamine B-PEG-SH (MW 10000)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 10000) (Rhodamine B-PEG-SH (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883D
-
|
Rhodamine B-PEG-SH (MW 3400)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 3400) (Rhodamine B-PEG-SH (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883A
-
|
Rhodamine B-PEG-SH (MW 600)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 4600) (Rhodamine B-PEG-SH (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883
-
|
Rhodamine B-PEG-SH (MW 400)
|
Fluorescent Dye
|
Others
|
|
RB-PEG-SH (MW 400) (Rhodamine B-PEG-SH (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D1730A
-
|
|
Fluorescent Dye
|
Others
|
|
AF488 NHS ester TEA is an amine specific fluorescence probe (λem=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-D2530
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2532
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2529
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-SH (MW 2000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2509
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2531
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2512
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2556
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2557
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-15917A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
L-Dithiothreitol (DTT) is a reducing agent commonly used in various biochemical applications to break disulfide bonds in proteins, thereby denaturing proteins or preventing the formation of unwanted aggregates. DTT has a unique chemical property that cleaves the sulfur-sulfur bond in the disulfide bond to form a sulfhydryl group. This makes it a useful tool for protein purification, enzyme assays, and protein structure studies.
|
-
- HY-D2559
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2558
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2589
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).
|
-
- HY-W800679
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-Cyclohexyl-PEG3-Biotin is a PEG linker containing a maleimide moiety and a biotin group. Maleimides react specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The biotinylation can react with amine molecules in the presence of activator EDC or HATU. PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein. The PEG moiety also increases solubility of Biotin-PEG conjugates considerably.
|
-
- HY-D2448
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG-Thiol (Cy3-PEG-SH) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-Thiol is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-135233
-
|
SATA
|
Biochemical Assay Reagents
|
Others
|
|
N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies .
|
-
- HY-D2513
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG-SH (MW 10000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 10000) is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-D2510
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG-SH (MW 2000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 2000) is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-D2511
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG-SH (MW 3400) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 3400) is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-66019
-
FITC
Maximum Cited Publications
60 Publications Verification
Fluorescein 5-isothiocyanate
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D1260
-
|
PSH-red
|
Fluorescent Dyes/Probes
|
|
FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .
|
-
- HY-D1618
-
|
|
Dyes
|
|
Cyanine3 maleimide tetrafluoroborate is a specific labeling reagent for sulfhydryl groups with the λex of 550 nm and λem of 580 nm. Cyanine3 maleimide tetrafluoroborate can be used for protein and peptide labeling .
|
-
- HY-D1654
-
|
|
Fluorescent Dyes/Probes
|
|
BDP 581/591 maleimide is a linker of the BDP 581/591 dye. It has a long fluorescence lifetime and can be used for fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5, for the labeling of sulfhydryl groups of proteins and peptides.
|
-
- HY-D2182
-
|
|
Fluorescent Dyes/Probes
|
|
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
-
- HY-D2180
-
|
|
Fluorescent Dyes/Probes
|
|
Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
-
- HY-D1869
-
|
|
Fluorescent Dyes/Probes
|
|
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .
|
-
- HY-D2094
-
|
|
Protein Labeling
|
|
PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
|
-
- HY-D2763
-
|
|
Fluorescent Dyes/Probes
|
|
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
|
-
- HY-D1363
-
|
|
Fluorescent Dyes/Probes
|
|
BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .
|
-
- HY-D2883E
-
|
Rhodamine B-PEG-SH (MW 5000)
|
Dyes
|
|
RB-PEG-SH (MW 5000) (Rhodamine B-PEG-SH (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883B
-
|
Rhodamine B-PEG-SH (MW 1000)
|
Dyes
|
|
RB-PEG-SH (MW 1000) (Rhodamine B-PEG-SH (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883C
-
|
Rhodamine B-PEG-SH (MW 2000)
|
Dyes
|
|
RB-PEG-SH (MW 2000) (Rhodamine B-PEG-SH (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883H
-
|
Rhodamine B-PEG-SH (MW 10000)
|
Dyes
|
|
RB-PEG-SH (MW 10000) (Rhodamine B-PEG-SH (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883D
-
|
Rhodamine B-PEG-SH (MW 3400)
|
Dyes
|
|
RB-PEG-SH (MW 3400) (Rhodamine B-PEG-SH (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883A
-
|
Rhodamine B-PEG-SH (MW 600)
|
Dyes
|
|
RB-PEG-SH (MW 4600) (Rhodamine B-PEG-SH (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D2883
-
|
Rhodamine B-PEG-SH (MW 400)
|
Dyes
|
|
RB-PEG-SH (MW 400) (Rhodamine B-PEG-SH (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 546/610 nm) .
|
-
- HY-D1730A
-
|
|
Fluorescent Dyes/Probes
|
|
AF488 NHS ester TEA is an amine specific fluorescence probe (λem=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-D2530
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2532
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2529
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-SH (MW 2000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2509
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2531
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2512
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2556
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2557
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2559
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2558
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2589
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).
|
-
- HY-D2448
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-Thiol (Cy3-PEG-SH) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-Thiol is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-D2513
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-SH (MW 10000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 10000) is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-D2510
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-SH (MW 2000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 2000) is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-D2511
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-SH (MW 3400) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 3400) is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-66019
-
|
Fluorescein 5-isothiocyanate
|
Fluorescent Dyes/Probes
|
|
FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
|
| Cat. No. |
Product Name |
Type |
-
- HY-D0975
-
|
|
Biochemical Assay Reagents
|
|
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
|
-
- HY-W1048553C
-
|
|
Drug Delivery
|
|
Mal-PEG-NH2 TFA (MW 5000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553H
-
|
|
Drug Delivery
|
|
Mal-PEG-NH2 TFA (MW 40000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553A
-
|
|
Drug Delivery
|
|
Mal-PEG-NH2 TFA (MW 2000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553B
-
|
|
Drug Delivery
|
|
Mal-PEG-NH2 TFA (MW 3400) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553E
-
|
|
Drug Delivery
|
|
Mal-PEG-NH2 TFA (MW 20000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553
-
|
|
Drug Delivery
|
|
Mal-PEG-NH2 TFA (MW 1000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553D
-
|
|
Drug Delivery
|
|
Mal-PEG-NH2 TFA (MW 10000) is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-174941
-
|
|
Drug Delivery
|
|
Mal-PEG18-acid is a PEG derivative modified with maleimide groups. Maleimide is a functional group that can undergo Michael addition reaction with sulfhydryl (–SH) groups and can be used for bioconjugation.
|
-
- HY-W698574
-
|
|
Indicators
|
|
Dansylamidoethyl mercaptan is a molecule that reacts with -SH groups of proteins and other sulfhydryl-containing molecules and has activity for detecting SS bonds in proteins.
|
-
- HY-W190746
-
|
|
Drug Delivery
|
|
Mal-PEG1-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
|
-
- HY-W190755
-
|
|
Drug Delivery
|
|
Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
|
-
- HY-W1048555B
-
|
|
Drug Delivery
|
|
Mal-PEG-SCM (MW 3400) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 3400) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555A
-
|
|
Drug Delivery
|
|
Mal-PEG-SCM (MW 2000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 2000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555D
-
|
|
Drug Delivery
|
|
Mal-PEG-SCM (MW 10000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 10000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555H
-
|
|
Drug Delivery
|
|
Mal-PEG-SCM (MW 40000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 40000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555C
-
|
|
Drug Delivery
|
|
Mal-PEG-SCM (MW 5000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 5000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555E
-
|
|
Drug Delivery
|
|
Mal-PEG-SCM (MW 20000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 20000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555
-
|
|
Drug Delivery
|
|
Mal-PEG-SCM (MW 1000) is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG-SCM (MW 1000) is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W588728
-
|
|
Drug Delivery
|
|
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W588736
-
|
|
Drug Delivery
|
|
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W440718C
-
|
|
Drug Delivery
|
|
Cholesterol-PEG-Mal (MW 10000) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W440718A
-
|
|
Drug Delivery
|
|
Cholesterol-PEG-Mal (MW 400) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W440718B
-
|
|
Drug Delivery
|
|
Cholesterol-PEG-Mal (MW 600) is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953B
-
|
|
Drug Delivery
|
|
TPP-PEG-Mal (MW 3400) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953D
-
|
|
Drug Delivery
|
|
TPP-PEG-Mal (MW 10000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953A
-
|
|
Drug Delivery
|
|
TPP-PEG-Mal (MW 2000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953
-
|
|
Drug Delivery
|
|
TPP-PEG-Mal (MW 1000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953C
-
|
|
Drug Delivery
|
|
TPP-PEG-Mal (MW 5000) is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174921
-
|
|
Drug Delivery
|
|
Maleimide-PEG-COOH (MW 1000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-174921B
-
|
|
Drug Delivery
|
|
Maleimide-PEG-COOH (MW 3400) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-174921C
-
|
|
Drug Delivery
|
|
Maleimide-PEG-COOH (MW 5000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-174921A
-
|
|
Drug Delivery
|
|
Maleimide-PEG-COOH (MW 2000) is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-W1048849A
-
|
4-Arm PEG-thiol (MW 5000)
|
Drug Delivery
|
|
4-Arm PEG-SH (MW 5000) (4-Arm PEG-thiol (MW 5000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-W1048849B
-
|
4-Arm PEG-thiol (MW 10000)
|
Drug Delivery
|
|
4-Arm PEG-SH (MW 10000) (4-Arm PEG-thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-W1048849D
-
|
4-Arm PEG-thiol (MW 40000)
|
Drug Delivery
|
|
4-Arm PEG-SH (MW 40000) (4-Arm PEG-thiol (MW 40000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-W1048849C
-
|
4-Arm PEG-thiol (MW 20000)
|
Drug Delivery
|
|
4-Arm PEG-SH (MW 20000) (4-Arm PEG-thiol (MW 20000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-W879049
-
|
DBCO-NHCO-PEG3-maleimide
|
Drug Delivery
|
|
DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-W879036
-
|
|
Drug Delivery
|
|
DBCO-PEG8-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG8-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-174961C
-
|
Fmoc-NH-PEG-Mal (MW 5000)
|
Drug Delivery
|
|
Fmoc-PEG-Maleimide (MW 5000) (Fmoc-NH-PEG-Mal (MW 5000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174961B
-
|
Fmoc-NH-PEG-Mal (MW 3400)
|
Drug Delivery
|
|
Fmoc-PEG-Maleimide (MW 3400) (Fmoc-NH-PEG-Mal (MW 3400)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174961
-
|
Fmoc-NH-PEG-Mal (MW 1000)
|
Drug Delivery
|
|
Fmoc-PEG-Maleimide (MW 1000) (Fmoc-NH-PEG-Mal (MW 1000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174961A
-
|
Fmoc-NH-PEG-Mal (MW 2000)
|
Drug Delivery
|
|
Fmoc-PEG-Maleimide (MW 2000) (Fmoc-NH-PEG-Mal (MW 2000)) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174927A
-
|
DBCO-PEG-Mal (MW 400)
|
Drug Delivery
|
|
DBCO-PEG-Maleimide (MW 400) (DBCO-PEG-Mal (MW 400)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 400) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927E
-
|
DBCO-PEG-Mal (MW 3400)
|
Drug Delivery
|
|
DBCO-PEG-Maleimide (MW 3400) (DBCO-PEG-Mal (MW 3400)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 3400) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927B
-
|
DBCO-PEG-Mal (MW 600)
|
Drug Delivery
|
|
DBCO-PEG-Maleimide (MW 600) (DBCO-PEG-Mal (MW 600)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 600) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927
-
|
DBCO-PEG-Mal (MW 5000)
|
Drug Delivery
|
|
DBCO-PEG-Maleimide (MW 5000) (DBCO-PEG-Mal (MW 5000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 5000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927D
-
|
DBCO-PEG-Mal (MW 2000)
|
Drug Delivery
|
|
DBCO-PEG-Maleimide (MW 2000) (DBCO-PEG-Mal (MW 2000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 2000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927C
-
|
DBCO-PEG-Mal (MW 1000)
|
Drug Delivery
|
|
DBCO-PEG-Maleimide (MW 1000) (DBCO-PEG-Mal (MW 1000)) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG-Maleimide (MW 1000) contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-167036C
-
|
|
Drug Delivery
|
|
DMG-PEG-Mal (MW 5000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 5000) can be used for drug delivery .
|
- HY-167036A
-
|
|
Drug Delivery
|
|
DMG-PEG-Mal (MW 1000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 1000) can be used for drug delivery .
|
- HY-167036D
-
|
|
Drug Delivery
|
|
DMG-PEG-Mal (MW 10000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 10000) can be used for drug delivery .
|
- HY-157920
-
|
N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine
|
Biochemical Assay Reagents
|
|
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
|
- HY-167036B
-
|
|
Drug Delivery
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DMG-PEG-Mal (MW 3400) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG-Mal (MW 3400) can be used for drug delivery .
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- HY-15917A
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Carbohydrates
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L-Dithiothreitol (DTT) is a reducing agent commonly used in various biochemical applications to break disulfide bonds in proteins, thereby denaturing proteins or preventing the formation of unwanted aggregates. DTT has a unique chemical property that cleaves the sulfur-sulfur bond in the disulfide bond to form a sulfhydryl group. This makes it a useful tool for protein purification, enzyme assays, and protein structure studies.
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- HY-135233
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SATA
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Biochemical Assay Reagents
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N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies .
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Product Name |
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Chemical Structure |
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Product Name |
Chemical Structure |
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- HY-D0843S
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N-Ethylmaleimide-d5 is the deuterium labeled N-Ethylmaleimide. N-Ethylmaleimide (NEM), a reagent that alkylates free sulfhydryl groups, is a cysteine protease inhibitor . N-ethylmaleimide specific inhibits phosphate transport in mitochondria . N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor .
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