stilbene derivative

By Targets:	Drug Derivative (1) HCV (1) Mitosis (1) NO Synthase (1) Polo-like Kinase (PLK) (1) Wnt (1)
By Research Areas:	Cancer (2) Infection (1) Inflammation/Immunology (2) Neurological Disease (1)

Targets Recommended: Drug Derivative

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13647

HMN-176	Polo-like Kinase (PLK) Mitosis	Cancer
HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1), without significant effect on tubulin polymerization.

HY-136145

FIDAS-3	Wnt	Cancer
FIDAS-3 is a stilbene derivative and is a potent Wnt inhibitor with an IC₅₀ of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A). FIDAS-3 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-3 has anticancer activities .

HY-149049

Cajaninstilbene acid Cajanine	HCV	Infection Inflammation/Immunology
Cajaninstilbene acid is a potent HCV inhibitor with an IC₅₀ of 3.17 μM. Cajaninstilbene acid inhibits HCV replications via down-regulates a cellular protein chondroitin sulfate N-acetylgalactosaminyltransferase 1 .

HY-116885

Thunalbene	NO Synthase	Inflammation/Immunology
Thunalbene is a stilbene derivative isolated from Thunia alba. Thunalbene has a weak inhibitory effect on nitric oxide production and is not cytotoxic .

HY-W614656

Pterostilbene glucoside	Drug Derivative	Neurological Disease
Pterostilbene glucoside, a stilbene derivative of Resveratrol (HY-16561), is a bioactive compound with potent protective effects against oxidative stress. Pterostilbene glucoside effectively protects M1 muscarinic receptor-transfected COS-7 cells from dopamine (DA)-induced deficits in calcium clearance. Pterostilbene glucoside can be used for the study of the reduction of age-related neuronal and behavioral deleterious effects .

Cat. No.	Product Name	Type

HY-W614656

Pterostilbene glucoside	Native Proteins
Pterostilbene glucoside, a stilbene derivative of Resveratrol (HY-16561), is a bioactive compound with potent protective effects against oxidative stress. Pterostilbene glucoside effectively protects M1 muscarinic receptor-transfected COS-7 cells from dopamine (DA)-induced deficits in calcium clearance. Pterostilbene glucoside can be used for the study of the reduction of age-related neuronal and behavioral deleterious effects .

Pterostilbene glucoside

Native Proteins

Pterostilbene glucoside, a stilbene derivative of Resveratrol (HY-16561), is a bioactive compound with potent protective effects against oxidative stress. Pterostilbene glucoside effectively protects M1 muscarinic receptor-transfected COS-7 cells from dopamine (DA)-induced deficits in calcium clearance. Pterostilbene glucoside can be used for the study of the reduction of age-related neuronal and behavioral deleterious effects .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-149049

Cajaninstilbene acid Cajanine	Simple Phenylpropanols Leguminosae Source classification Phenylpropanoids Plants Cajanus cajan (L.) Millsp.	HCV
Cajaninstilbene acid is a potent HCV inhibitor with an IC₅₀ of 3.17 μM. Cajaninstilbene acid inhibits HCV replications via down-regulates a cellular protein chondroitin sulfate N-acetylgalactosaminyltransferase 1 .

HY-116885

Thunalbene	Thunia alba (Lindl.) Rchb. F. Orchidaceae Source classification Phenols Plants	NO Synthase
Thunalbene is a stilbene derivative isolated from Thunia alba. Thunalbene has a weak inhibitory effect on nitric oxide production and is not cytotoxic .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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stilbene derivative

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