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skeleton

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Amino Acid Decarboxylase (1) Antibiotic (1) Apoptosis (2) Bacterial (7) BCRP (2) Biochemical Assay Reagents (1) Calmodulin (1) Cholinesterase (ChE) (2) Cytochrome P450 (1) DNA/RNA Synthesis (1) Drug Intermediate (5) Endogenous Metabolite (17) Estrogen Receptor/ERR (2) Farnesyl Transferase (3) Ferroptosis (1) Fluorescent Dye (2) Fungal (2) Glutaminase (1) GSK-3 (1) Histone Acetyltransferase (1) HIV (1) Isotope-Labeled Compounds (6) JAK (1) Liposome (2) Microtubule/Tubulin (1) NO Synthase (1) Nuclear Factor of activated T Cells (NFAT) (1) Nucleoside Antimetabolite/Analog (1) P2Y Receptor (1) Parasite (1) Phosphodiesterase (PDE) (1) Phytohormone (1) Reactive Oxygen Species (ROS) (1) Reference Standards (5) TGF-β Receptor (1) Tyrosinase (12) β-catenin (1)
By Research Areas:	Cancer (19) Endocrinology (1) Infection (10) Inflammation/Immunology (15) Metabolic Disease (17) Neurological Disease (12)
Oligonucleotides:	Antisense Oligonucleotides (1) Cholesterol (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W013636C

2-Ketoglutaric acid potassium 5 Publications Verification Alpha-Ketoglutaric acid potassium	Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) potassium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid potassium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid potassium is a reversible inhibitor of tyrosinase with an IC₅₀ value of 15 mM .

HY-W013636

2-Ketoglutaric acid 5 Publications Verification Alpha-Ketoglutaric acid; 2-Oxoglutaric acid	Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636B

Calcium 2-oxoglutarate 5 Publications Verification	Tyrosinase Endogenous Metabolite	Metabolic Disease
Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636A

2-Ketoglutaric acid Sodium 5 Publications Verification Alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S3

2-Ketoglutaric acid-13C Alpha-Ketoglutaric acid-¹³C	Isotope-Labeled Compounds Endogenous Metabolite Tyrosinase	Neurological Disease Metabolic Disease
2-Ketoglutaric acid- ¹³C (Alpha-Ketoglutaric acid- ¹³C) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636R

2-Ketoglutaric acid (Standard) 5 Publications Verification Alpha-Ketoglutaric acid (Standard); 2-Oxoglutaric acid (Standard)	Reference Standards Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Standard) (Alpha-Ketoglutaric acid (Standard)) is the analytical standard of 2-Ketoglutaric acid (HY-W013636). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-N3411

Labd-13(E)-ene-8α,15-diol 13E-Labdene-8α,15-diol; Copal-8α,15-diol	Others	Others
Labd-13(E)-ene-8α,15-diol is a diterpene with the labdane skeleton which can be extracted from Cistus symphytijbfolius .

HY-W013636AR

2-Ketoglutaric acid Sodium (Standard) Alpha-Ketoglutaric acid Sodium (Standard)	Reference Standards Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Sodium) (Standard) is the analytical standard of 2-Ketoglutaric acid Sodium (HY-W013636A). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (Standard) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636AG

2-Ketoglutaric acid Sodium Alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (GMP) is 2-Ketoglutaric acid Sodium (HY-W013636A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-N2528

Usnic acid sodium	Bacterial	Infection Cancer
Usnic acid sodium, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid sodium has excellent anticancer and antimicrobial properties. Usnic acid sodium significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1 .

HY-136473

CTX-0124143	Histone Acetyltransferase	Cancer
CTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton .

HY-N11896

10-Hydroxyaloin B	Others	Inflammation/Immunology
10-Hydroxyaloin B is a bioactive oxanthrone based on the aloin skeleton .

HY-N14937

Albaflavenone	Antibiotic Bacterial Fungal	Infection
Albaflavenone is a sesquiterpene antibiotic with a zizaene skeleton. Albaflavenone is active against Bacillus subtilis .

HY-N9604

Andrastin C	Farnesyl Transferase	Cancer
Andrastin B is a protein farnesyltransferase inhibitor. Andrastin B has a common androstane skeleton .

HY-N1303

Shoreic acid Shoric acid	Others	Others
Shoreic acid (compound 8a) is a dammarane skeleton compound isolated from Cabralea eichleriana DC .

HY-133209

Fischeria A	Others	Cancer
Fischeria A is a norditerpene lactone of a new carbon skeleton, can be isolated from Euphorbia fischeriana .

HY-N13874

Andrastin B	Farnesyl Transferase	Cancer
Andrastin C is a protein farnesyltransferase inhibitor. Andrastin C has a common androstane skeleton .

HY-N13876

Andrastin D	Farnesyl Transferase	Cancer
Andrastin D is a protein farnesyltransferase inhibitor. Andrastin D has a common androstane skeleton .

HY-135324

4,4'-Iminodiphenol	Estrogen Receptor/ERR	Endocrinology
4-Propionamidophenol (compound 4a) is an inactive estrogen receptor ligand based on the diphenylamine skeleton .

HY-126613

Laurycolactone A	Others	Others
Laurycolactone A is a quassinoid with a C18 basic skeleton. Laurycolactone A can be isolated from Eurycoma longifolia .

HY-W007771

Acridone	Bacterial BCRP	Infection Cancer
Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .

HY-N11663

Dugesin C	Others	Others
Dugesin C is a diterpenoid isolated from the plant Salvia dugesii with a spiro carbocyclic ring system derived from the normal neocrotane skeleton .

HY-U00190

Deprodone propionate RD20000	Bacterial	Inflammation/Immunology
Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position.

HY-157779

TPA-NAC	Reactive Oxygen Species (ROS)	Metabolic Disease
TPA-NAC is a nonfluorogenic prodrug by introducing N-acetyl-L-cysteine (NAC) into a conjugated acceptor skeleton. TPA-NAC is capable of fluorogenic selective labeling of HSA .

HY-N12478

Ainsliadimer A	NO Synthase	Inflammation/Immunology
Ainsliadimer A is a sesquiterpene lactone dimer with an unusual carbon skeleton. Ainsliadimer A can be obtained from from Ainsliaea macrocephala. Ainsliadimer A inhibits the production of nitric oxide in cells stimulated by LPS .

HY-W013973

p-Terphenyl	Drug Intermediate	Inflammation/Immunology Cancer
p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

HY-W016349

Chelidamic acid	Amino Acid Decarboxylase	Others
Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a K_i of 33 μM.

HY-W142374

5-Bromogramine	Biochemical Assay Reagents	Others
5-Bromogramine is an indole skeleton substituted with Br and CH3 at certain positions. 5-Bromogramine shows antifouling activity, with IC₉₉ of 0.25 ppm .

HY-N6849

InteriotherinA	HIV	Infection Metabolic Disease
Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent .

HY-W007771R

Acridone (Standard)	Reference Standards Bacterial BCRP	Infection Cancer
Acridone (Standard) is the analytical standard of Acridone. This product is intended for research and analytical applications. Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .

HY-N9345

(2α,3β)-Olean-12-ene-2,3-diol	Others	Others
(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid with lupane, oleanane, and ursane skeleton .

HY-138913

2H-Cho-Arg TFA	Liposome	Cancer
2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

HY-N6894

Pseudocoptisine acetate Isocoptisine acetate	Cholinesterase (ChE)	Inflammation/Immunology
Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine acetate inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-N6894A

Pseudocoptisine chloride Isocoptisine chloride	Cholinesterase (ChE)	Inflammation/Immunology
Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-N11977

Stenophyllol B	Others	Others
Stenophyllol B (compound 4) is a trimeric stilbene with bicyclic and bridged tricyclic skeletons. Stenophyllol B was first discovered in the dipterocarps plant and has been found in many species of Hopea, Neobalanocarpus, Shorea, Stemonoporus and Vateri .

HY-N11015

Withaphysalin R	Others	Infection Inflammation/Immunology Cancer
Withaphysalin R (compound 5) is a Withanolide that can be isolated from the Solanaceae. Withanolide is a steroid ester with an ergosterol skeleton, and some of these compounds have some significant activities, including cytotoxic and immunosuppressive, antitumor, anti-inflammatory, anticonvulsive, and antioxidant .

HY-N7550

Latrunculin M	Fluorescent Dye	Others
Latrunculin M is a highly selective actin-macrolide conjugate that can be isolated from marine products. Latrunculin M can be converted from Latrunculin B, which can effectively induce actin depolymerization and is a good probe for detecting the actin skeleton.

HY-N11646

Ganorbiformin B	Bacterial	Infection
Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .

HY-121162

Mesembrine (+)-Mesembrine	5-HT Receptor Phosphodiesterase (PDE)	Neurological Disease
Mesembrine ((+)-Mesembrine) a main alkaloid that features an aryloctahydroindole skeleton. Mesembrine is a 5-HT transporter inhibitor with a K_i of 1.4 nM. Mesembrine also inhibits phosphodiesterase 4B (PDE4B) with an IC₅₀ of 7.8 μM .

HY-N0829

Shionone	Others	Inflammation/Immunology
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-N10697

Angulatin G Celangulatin E	Parasite	Infection
Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD₅₀ against Mythimna separata of 1656.4 μg/mL .

HY-N2936

Bi-linderone	Others	Others
Bi-linderone is isolated as racemate from the traditional Chinese medicinal plant Lindera aggregata. Bi-linderone has activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 μg/mL .

HY-151109

IR-990	Fluorescent Dye	Others
IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H₂O₂ in vivo. IR-990 is a powerful diagnosis of agent-induced liver injury (DILI) .

HY-Y0135

Tropinone	Drug Intermediate	Cancer
Tropinone is an organic synthesis intermediate and a skeleton for constructing derivatives containing thiazole rings and other structures. Tropinone derivatives have anticancer activities such as inducing tumor cell apoptosis and inhibiting tyrosinase activity, and can be used in research such as anticancer drug development and tyrosinase inhibitor design .

HY-W013973R

p-Terphenyl (Standard)	Reference Standards Drug Intermediate	Inflammation/Immunology Cancer
p-Terphenyl (Standard) is the analytical standard of p-Terphenyl. This product is intended for research and analytical applications. p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

HY-N2920

β-Amyrenonol 11-Oxo-β-amyrin	Cytochrome P450	Inflammation/Immunology Cancer
β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids .

HY-P2733

Glycerol-3-phosphate oxidase, E. coli GPO	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .

HY-163634

YZK-C22	Fungal	Infection
YZK-C22, containing a 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole skeleton, is a fungicide lead compound with broad-spectrum fungicidal activity .

HY-W013973S

p-Terphenyl-d14	Isotope-Labeled Compounds Drug Intermediate	Inflammation/Immunology Cancer
p-Terphenyl-d₁₄ is the deuterium labeled p-Terphenyl (HY-W013973). p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

HY-W006187

2-Amino-2-(p-tolyl)acetic acid	Glutaminase	Cancer
2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI) .

Cat. No.	Product Name	Type

HY-W013636AG

2-Ketoglutaric acid Sodium (GMP)

Alpha-Ketoglutaric acid Sodium (GMP)

Fluorescent Dye

2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (GMP) is 2-Ketoglutaric acid Sodium (HY-W013636A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

Cat. No.	Product Name	Type

HY-W013636C

2-Ketoglutaric acid potassium 5 Publications Verification Alpha-Ketoglutaric acid potassium	Biochemical Assay Reagents
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) potassium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid potassium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid potassium is a reversible inhibitor of tyrosinase with an IC₅₀ value of 15 mM .

HY-W013973

p-Terphenyl	Biochemical Assay Reagents
p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

HY-W013636AG

2-Ketoglutaric acid Sodium (GMP)

Alpha-Ketoglutaric acid Sodium (GMP)

Biochemical Assay Reagents

HY-W013973R

p-Terphenyl (Standard)	Biochemical Assay Reagents
p-Terphenyl (Standard) is the analytical standard of p-Terphenyl. This product is intended for research and analytical applications. p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

Cat. No.	Product Name	Target	Research Area

HY-W006187

2-Amino-2-(p-tolyl)acetic acid	Glutaminase	Cancer
2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W013636

2-Ketoglutaric acid 5 Publications Verification Alpha-Ketoglutaric acid; 2-Oxoglutaric acid	Structural Classification Classification of Application Fields Anti-aging Source classification Endocrine diseases Endogenous metabolite Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Other Diseases Nervous System Disorder Disease Research Fields	Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636B

Calcium 2-oxoglutarate 5 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Tyrosinase Endogenous Metabolite
Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636A

2-Ketoglutaric acid Sodium 5 Publications Verification Alpha-Ketoglutaric acid Sodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636R

2-Ketoglutaric acid (Standard) 5 Publications Verification Alpha-Ketoglutaric acid (Standard); 2-Oxoglutaric acid (Standard)	Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite	Reference Standards Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Standard) (Alpha-Ketoglutaric acid (Standard)) is the analytical standard of 2-Ketoglutaric acid (HY-W013636). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-N11896

10-Hydroxyaloin B	Structural Classification Natural Products Aloe claviflora Burch. Source classification Plants Asphodelaceae	Others
10-Hydroxyaloin B is a bioactive oxanthrone based on the aloin skeleton .

HY-N3411

Labd-13(E)-ene-8α,15-diol 13E-Labdene-8α,15-diol; Copal-8α,15-diol	Structural Classification Terpenoids Source classification Diterpenoids Cistaceae Juss. Plants Cistus symphytifolius Lam.	Others
Labd-13(E)-ene-8α,15-diol is a diterpene with the labdane skeleton which can be extracted from Cistus symphytijbfolius .

HY-W013636AR

2-Ketoglutaric acid Sodium (Standard) Alpha-Ketoglutaric acid Sodium (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Sodium) (Standard) is the analytical standard of 2-Ketoglutaric acid Sodium (HY-W013636A). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (Standard) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-N14937

Albaflavenone	Structural Classification Natural Products Microorganisms Terpenoids Sesquiterpenes Source classification	Antibiotic Bacterial Fungal
Albaflavenone is a sesquiterpene antibiotic with a zizaene skeleton. Albaflavenone is active against Bacillus subtilis .

HY-N1303

Shoreic acid Shoric acid	Structural Classification Ketones, Aldehydes, Acids Source classification Cabralea eichleriana DC. Plants Meliaceae	Others
Shoreic acid (compound 8a) is a dammarane skeleton compound isolated from Cabralea eichleriana DC .

HY-133209

Fischeria A	Structural Classification Terpenoids Source classification Diterpenoids Euphorbiaceae Plants Euphorbia kansuensis Prokh.	Others
Fischeria A is a norditerpene lactone of a new carbon skeleton, can be isolated from Euphorbia fischeriana .

HY-N13874

Andrastin B	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Farnesyl Transferase
Andrastin C is a protein farnesyltransferase inhibitor. Andrastin C has a common androstane skeleton .

HY-N13876

Andrastin D	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Farnesyl Transferase
Andrastin D is a protein farnesyltransferase inhibitor. Andrastin D has a common androstane skeleton .

HY-126613

Laurycolactone A	Natural Products Simaroubaceae Plants	Others
Laurycolactone A is a quassinoid with a C18 basic skeleton. Laurycolactone A can be isolated from Eurycoma longifolia .

HY-W007771

Acridone	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	Bacterial BCRP
Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .

HY-N11663

Dugesin C	Structural Classification Gynoxys verrucosa Sch.Bip. ex Wedd. Terpenoids Labiatae Source classification Diterpenoids Plants	Others
Dugesin C is a diterpenoid isolated from the plant Salvia dugesii with a spiro carbocyclic ring system derived from the normal neocrotane skeleton .

HY-N12478

Ainsliadimer A	Structural Classification Caesalpinia crista L. Terpenoids Sesquiterpenes Source classification Plants Compositae	NO Synthase
Ainsliadimer A is a sesquiterpene lactone dimer with an unusual carbon skeleton. Ainsliadimer A can be obtained from from Ainsliaea macrocephala. Ainsliadimer A inhibits the production of nitric oxide in cells stimulated by LPS .

HY-N6849

InteriotherinA	Structural Classification Classification of Application Fields Source classification Lignans Metabolic Disease Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields	HIV
Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent .

HY-W007771R

Acridone (Standard)	Structural Classification Natural Products other families Source classification Plants	Reference Standards Bacterial BCRP
Acridone (Standard) is the analytical standard of Acridone. This product is intended for research and analytical applications. Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .

HY-N9345

(2α,3β)-Olean-12-ene-2,3-diol	Triterpenes other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Others
(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid with lupane, oleanane, and ursane skeleton .

HY-N6894

Pseudocoptisine acetate Isocoptisine acetate	Alkaloids Phellodendron amurense Rupr. Classification of Application Fields Source classification Rutaceae Plants Isoquinoline Alkaloids Disease Research Fields Inflammation/Immunology	Cholinesterase (ChE)
Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine acetate inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-N6894A

Pseudocoptisine chloride Isocoptisine chloride	Alkaloids Piperidine Alkaloids Classification of Application Fields Source classification Plants Isoquinoline Alkaloids Disease Research Fields Inflammation/Immunology Papaveraceae Corydalis turtschaninovii Bess.	Cholinesterase (ChE)
Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-N11977

Stenophyllol B	Structural Classification Source classification Phenols Polyphenols Plants Dipterocarpaceae Vatica umbonata (Hook.f.) Burck	Others
Stenophyllol B (compound 4) is a trimeric stilbene with bicyclic and bridged tricyclic skeletons. Stenophyllol B was first discovered in the dipterocarps plant and has been found in many species of Hopea, Neobalanocarpus, Shorea, Stemonoporus and Vateri .

HY-N11015

Withaphysalin R	Structural Classification Physalis minima Linn. Source classification Plants Solanaceae Steroids	Others
Withaphysalin R (compound 5) is a Withanolide that can be isolated from the Solanaceae. Withanolide is a steroid ester with an ergosterol skeleton, and some of these compounds have some significant activities, including cytotoxic and immunosuppressive, antitumor, anti-inflammatory, anticonvulsive, and antioxidant .

HY-N7550

Latrunculin M	Structural Classification Natural Products Marine natural products Source classification Sponge	Fluorescent Dye
Latrunculin M is a highly selective actin-macrolide conjugate that can be isolated from marine products. Latrunculin M can be converted from Latrunculin B, which can effectively induce actin depolymerization and is a good probe for detecting the actin skeleton.

HY-N11646

Ganorbiformin B	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Bacterial
Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .

HY-121162

Mesembrine (+)-Mesembrine	Alkaloids other families Pyrrole Alkaloids Source classification Plants	5-HT Receptor Phosphodiesterase (PDE)
Mesembrine ((+)-Mesembrine) a main alkaloid that features an aryloctahydroindole skeleton. Mesembrine is a 5-HT transporter inhibitor with a K_i of 1.4 nM. Mesembrine also inhibits phosphodiesterase 4B (PDE4B) with an IC₅₀ of 7.8 μM .

HY-N0829

Shionone	Structural Classification Classification of Application Fields Terpenoids Diterpenoids Plants Compositae Sesbania vesicaria (Jacq.) Elliott Inflammation/Immunology Disease Research Fields	Others
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-N10697

Angulatin G Celangulatin E	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Parasite
Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD₅₀ against Mythimna separata of 1656.4 μg/mL .

HY-N2936

Bi-linderone	Structural Classification Natural Products Source classification Plants Lauraceae Lindera aggregata (Sims) Kosterm.	Others
Bi-linderone is isolated as racemate from the traditional Chinese medicinal plant Lindera aggregata. Bi-linderone has activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 μg/mL .

HY-N2920

β-Amyrenonol 11-Oxo-β-amyrin	Structural Classification Natural Products Classification of Application Fields Source classification Myrtaceae Rhodomyrtus tomentosa Plants Inflammation/Immunology Disease Research Fields	Cytochrome P450
β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids .

HY-N0829R

Shionone (Standard)	Structural Classification Terpenoids Diterpenoids Plants Compositae Sesbania vesicaria (Jacq.) Elliott	Reference Standards Others
Shionone (Standard) is the analytical standard of Shionone. This product is intended for research and analytical applications. Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-N0656

Usnic acid 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Plants Infection Usnea diffracta Vain. Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Usneaceae	Bacterial DNA/RNA Synthesis Nuclear Factor of activated T Cells (NFAT) Apoptosis
Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase .

Cat. No.	Product Name	Chemical Structure

HY-W013636S3

2-Ketoglutaric acid-13C

2-Ketoglutaric acid- ¹³C (Alpha-Ketoglutaric acid- ¹³C) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S1

2-Ketoglutaric acid-d4

2-Ketoglutaric acid-d₄ (Alpha-Ketoglutaric acid-d₄) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S2

2-Ketoglutaric acid-d6
2-Ketoglutaric acid-d₆ (Alpha-Ketoglutaric acid-d₆) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S

2-Ketoglutaric acid-13C5

2-Ketoglutaric acid- ¹³C₅ (Alpha-Ketoglutaric acid- ¹³C₅) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013973S

p-Terphenyl-d14
p-Terphenyl-d₁₄ is the deuterium labeled p-Terphenyl (HY-W013973). p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

HY-W013636S4

2-Ketoglutaric acid-13C2

2-Ketoglutaric acid- ¹³C₂ (Alpha-Ketoglutaric acid- ¹³C₂) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

Cat. No.	Product Name		Classification

HY-138913

2H-Cho-Arg TFA		Cholesterol
2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

HY-153734

Inactive ASO (in vivo) sodium		Antisense Oligonucleotides
Inactive ASO (in vivo) sodium is an inactive Antisense Oligonucleotide. ASO is a class of oligonucleotide molecules, usually composed of 20-30 bases, used to interfere with or regulate gene expression. Inactive ASO (in vivo) sodium is not targeted in the rodent genome and can be used as a negative control for Tofersen. Inactive ASO (in vivo) sodium contains thiophosphate skeleton modification and MOE modification. Cytosine in Inactive ASO (in vivo) is 5' methylcytosine. See References for the location of chemical modifications

HY-138912

Cho-Arg TFA		Cholesterol
Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy .

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