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Results for "

sesquiterpenoids

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Akt (2) Amyloid-β (1) AP-1 (1) Apoptosis (8) Autophagy (4) Bacterial (9) Beta-secretase (1) c-Met/HGFR (1) Cholinesterase (ChE) (1) COX (1) Drug Derivative (1) Endogenous Metabolite (3) ERK (2) Estrogen Receptor/ERR (1) Ferroptosis (2) Fungal (9) GABA Receptor (2) Glutathione Peroxidase (2) Heme Oxygenase (HO) (2) HSV (1) Indoleamine 2,3-Dioxygenase (IDO) (2) Interleukin Related (2) Isotope-Labeled Compounds (1) Keap1-Nrf2 (3) Monoamine Oxidase (1) NF-κB (5) NO Synthase (2) p38 MAPK (3) Parasite (1) Potassium Channel (1) RAD51 (2) Reactive Oxygen Species (ROS) (4) Reference Standards (5) Serotonin Transporter (1) SOD (1) Src (2) STAT (2) TGF-beta/Smad (1) TGF-β Receptor (2) TNF Receptor (1) Toll-like Receptor (TLR) (2) Tyrosinase (1)
By Research Areas:	Cancer (24) Cardiovascular Disease (6) Infection (16) Inflammation/Immunology (17) Metabolic Disease (2) Neurological Disease (12)

By Targets:

5-HT Receptor (2)

Akt (2)

Amyloid-β (1)

AP-1 (1)

Apoptosis (8)

Autophagy (4)

Bacterial (9)

Beta-secretase (1)

c-Met/HGFR (1)

Cholinesterase (ChE) (1)

COX (1)

Drug Derivative (1)

Endogenous Metabolite (3)

ERK (2)

Estrogen Receptor/ERR (1)

Ferroptosis (2)

Fungal (9)

GABA Receptor (2)

Glutathione Peroxidase (2)

Heme Oxygenase (HO) (2)

HSV (1)

Indoleamine 2,3-Dioxygenase (IDO) (2)

Interleukin Related (2)

Isotope-Labeled Compounds (1)

Keap1-Nrf2 (3)

Monoamine Oxidase (1)

NF-κB (5)

NO Synthase (2)

p38 MAPK (3)

Parasite (1)

Potassium Channel (1)

RAD51 (2)

Reactive Oxygen Species (ROS) (4)

Reference Standards (5)

Serotonin Transporter (1)

SOD (1)

Src (2)

STAT (2)

TGF-beta/Smad (1)

TGF-β Receptor (2)

TNF Receptor (1)

Toll-like Receptor (TLR) (2)

Tyrosinase (1)

By Research Areas:

Cancer (24)

Cardiovascular Disease (6)

Infection (16)

Inflammation/Immunology (17)

Metabolic Disease (2)

Neurological Disease (12)

240

Inhibitors & Agonists

232

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N10321

Kanshone C	Others	Others
Kanshone C is a sesquiterpenoid of Nardostachys chinensis roots .

HY-122375

Palustrol	Others	Others
Palustrol is a natural sesquiterpenoid compound .

HY-N8736

Eicosanyl (E)-caffeate	Others	Others
Eicosanyl (E)-caffeate is a sesquiterpenoid isolated from the root of Wikstroemia scytophylla .

HY-134572

(2S,3S)-Pterosin C	Others	Others
(2S,3S)-Pterosin C is a natural sesquiterpenoid compound .

HY-N1571

Pterosin D	Others	Others
Pterosin D is a sesquiterpenoid, that can be isolated from aerial plants of P. cretica .

HY-N3174

(2R)-Norpterosin B	Others	Others
(2R)-Norpterosin B is a sesquiterpenoid isolated from Pteris semipinnata .

HY-N10163

1β,10β-Epoxydesacetoxymatricarin (+)-1β,10β-Epoxydesacetoxymatricarin	Others	Others
1β,10β-Epoxydesacetoxymatricarin is a sesquiterpenoids that can be isolated from Carthamus oxycantha .

HY-N11480

(2E)-Leocarpinolide F	Others	Others
(2E)-Leocarpinolide F (Compound 20), a germacrane-type sesquiterpenoid, can be isolated from Sigesbeckia orientalis .

HY-N7606

(Rac)-β-Chamigrenic acid	Others	Others
(Rac)-β-Chamigrenic acid is a racemate of β-Chamigrenic acid. β-Chamigrenic acid is a sesquiterpenoid isolated from S.chinensis

HY-N12266

12-Hydroxyalbrassitriol	Others	Others
12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .

HY-171795

Isolubimin	Bacterial Fungal	Infection
Isolubimin is a sesquiterpenoid phytoalexin found in Datura stramonium fruits with antibacterial activity. Isolubimin is promising for research of plant disease caused by fungal infections .

HY-N12191

Cangorinine E-1	HSV	Others
Cangorinine E-1 (compound 11) is a dihydroagarofuran derivative of the sesquiterpenoid family. Cangorinine E-1 exhibits weak inhibitory effects on herpes simplex virus type II (HSV) .

HY-N10218

Sterpurol D	Others	Inflammation/Immunology
Sterpurol D is a compound of the sterpurane sesquiterpenoid. Sterpurol D significantly inhibits nitric oxide (NO) production .

HY-N10683

1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran	Others	Others
1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran is a sesquiterpenoid isolated from the root bark of Tripterygium hypoglaucum containing a benzoyl and a cinnamoyl group .

HY-N8103

Heishuixiecaoline A	Amyloid-β	Neurological Disease
Heishuixiecaoline A is a germacrane-type sesquiterpenoid. Heishuixiecaoline A shows protective effect on the neurotoxicity of PC12 cells induced by Aβ_25-35 .

HY-176245

Illudinine	Monoamine Oxidase	Neurological Disease
Illudinine, a sesquiterpenoid alkaloid, is a monoamine oxidase B (MAO-B) inhibitor with an IC₅₀ of 18.3 μM. Illudinine can be used for research on neurological diseases .

HY-119735

Curcolone	Others	Cardiovascular Disease
Curcolone is a sesquiterpenoid that inhibits collagen-induced or arachidonic acid (AA)-induced platelet aggregation .

HY-N10014

Bulnesol	Fungal	Infection
Bulnesol is a sesquiterpenoid that can be isolated from Salvia dorystaechas. Bulnesol inhibits the activity of Fusarium moniliforme with an EC₅₀ value of 0.6 mg/mL. Bulnesol can be used for the research of fungal infection .

HY-N8934

6β-Hydroxytomentosin	Others	Cancer
6β-Hydroxytomentosin, a sesquiterpenoid, can be found in flowers of Inula japonica. 6β-Hydroxytomentosin exhibits weak cytotoxicities against A549, SK-OV-3, HepG-2 and HT-29 cell lines .

HY-N8136

Volvalerenic acid A	Others	Others
Volvalerenic acid A is a germacrane-type sesquiterpenoid that can be found in the roots of Valeriana officinalis var. latifolia .

HY-N16131

Sydonic acid	Drug Derivative	Others
Sydonic acid is a bisabolane-type sesquiterpenoid that can be isolated from the fungus Aspergillus sydowii BTBU20213012, which was obtained from a marine sediment sample in the Western Pacific .

HY-N3879

Eudesm-4(14)-ene-3α,11-diol	Others	Others
Eudesm-4(14)-ene-3α,11-diol (compound 2) is a sesquiterpenoid. Eudesm-4(14)-ene-3α,11-diol can be isolated from Neocallitropsis Pancheri Florin .

HY-N8862

Anti-inflammatory agent 69	Others	Inflammation/Immunology
Anti-inflammatory agent 69 (compound 12), sesquiterpenoid, is an anti-inflammatory agent isolated from the dried flower buds of Tussilago farfara. Anti-inflammatory agent 69 can inhibit the NO production with IC₅₀ value of 24 μM .

HY-N5081

1αH,5αH-Guaia-6-ene-4β,10β-diol	Others	Cancer
1αH,5αH-Guaia-6-ene-4β,10β-diol is a sesquiterpenoid derivative identified from Alisma orientale. 1αH,5αH-Guaia-6-ene-4β,10β-diol has anti-cancer activities .

HY-N3241

Mucrolidin	Bacterial	Infection
Mucrolidin is an eudesmane-type sesquiterpenoid isolated from aerial parts of homalomena occulta. Mucrolidin exhibits weak antibacterial activities when it compares to Rifampicin (HY-B0272) .

HY-N10458

Asperbisabolane L	NF-κB	Inflammation/Immunology
Asperbisabolane L, a sesquiterpenoid, exerts the anti-inflammatory activity by inhibiting the NF-κB-activated pathway. Asperbisabolane L inhibits the translocation of NF-κB from cytoplasm to the nucleus. Asperbisabolane L also inhibits NO production in LPS-activated BV-2 microglia cells .

HY-N10116A

Calamenene	Others	Cancer
Calamenene is a major sesquiterpenoid, which could be isolated from Cupressus bakeri foliage. Calamenene affects the maturation and function of human monocyte-derived dendritic cells .

HY-N9239

Turmeronol A	Others	Others
Turmeronol A is a sesquiterpenoid compound. Turmeronol A has anti-inflammatory activity. Turmeronol A prevents macrophage activation and the production of inflammatory mediators by inhibiting the activation of NFκB. Turmeronol A can be used to prevent chronic inflammatory diseases .

HY-N3340

Macrocarpal I	Fungal	Infection
Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC₅₀ value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni .

HY-N8404

Chlorahololide C	Potassium Channel	Inflammation/Immunology
Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC₅₀ of 3.6 μM .

HY-N9046

Citroside A	NO Synthase	Inflammation/Immunology Cancer
Citroside A is a megastigmane sesquiterpenoid with cytotoxic and anti-inflammatory activities. Citroside A displays potential effects against NO production with an IC₅₀ of 34.25 μM. Citroside A exhibits pronounced cytotoxicity against SGC-7901 and HeLa cells with IC₅₀ values of 27.52 μM and 29.51 μM, respectively .

HY-N10364

6β,7β-Epoxyasteriscunolide A	Others	Cancer
6β,7β-Epoxyasteriscunolide A, a sesquiterpenoid, shows cytotoxicity against the HL-60 and MOLT-3 leukemia cell lines, with IC₅₀s range 4.1-5.4 μM .

HY-N15479

Nanangenine F	Bacterial	Infection Cancer
Nanangenine F is a drimane sesquiterpenoid with weak antibacterial and anticancer activities. Nanangenine F inhibits Bacillus subtilis (ATCC 6633) with an IC₅₀ of 78 µg/mL. Nanangenine F inhibits NS-1, DU-145, MCF-7 and human fibroblast NFF cells with IC₅₀s of 49 µg/mL, 95 µg/mL, 49 µg/mL, and 84 µg/mL, respectively .

HY-N12475

Solavetivone	Fungal	Infection
Solavetivone is a sesquiterpenoid potato phytoalexin. Solavetivone can be isolated from the root of Solanum xanthocarpum. Solavetivone has potent toxicity and anti-microbial activity, and it can protect solanaceous plants against pathogens. Solavetivone can be used for crops produce research .

HY-N0104

Curcumol Maximum Cited Publications 9 Publications Verification (-)-Curcumol	Apoptosis	Cancer
Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers .

HY-N10577

Chlorfortunone A	TGF-beta/Smad	Cancer
Chlorfortunone A is a novel sesquiterpenoid dimers, can be isolated from the roots of Chloranthus fortunei. Chlorfortunone A inhibits transforming growth factor (TGF)-β activity .

HY-N0104R

Curcumol (Standard) (-)-Curcumol (Standard)	Reference Standards Apoptosis	Cancer
Curcumol (Standard) is the analytical standard of Curcumol. This product is intended for research and analytical applications. Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers .

HY-N16123

Chloranthalactone C	Parasite	Infection
Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research .

HY-W587689

Juvenile hormone B 3 (mixture of diastereomers) Juvenile hormone III bisepoxide; Juvenile hormone bisepoxide; JHB3	c-Met/HGFR	Others
Juvenile hormone B 3 (Juvenile hormone III bisepoxide)(mixture of diastereomers) is a sesquiterpenoid hormone. Juvenile hormone B 3 can be isolated from corpus allatum (CA) of high dipterans like the fruitfly and Drosophila melanogaster. JHB3 has anti-metamorphic activity and induces Kr-h1 expression by directly interacting with juvenile hormone (JH) receptors (Met and Gce). Juvenile hormone B 3 can be used for insect lethality research .

HY-N2885

Apocynol A	Others	Others
Apocynol A is a sesquiterpenoid compound .

HY-N15617

Rishitinone	Fungal	Infection
Rishitinone is a sesquiterpenoid with antifungal activity .

HY-N8312

Bakkenolide IIIa	Others	Others
Bakkenolide IIIa is a natural sesquiterpenoid compound .

HY-N10623

5-epi-Arvestonate A	Tyrosinase	Cancer
5-epi-Arvestonate A is a sesquiterpenoid isolated from the whole plants of Seriphidium transiliense. 5-epi-Arvestonate A promotes melanogenic production by activating the transcription of microphthalmia-associated transcription factor (MITF) and tyrosinase family genes. 5-epi-Arvestonate A inhibits the expression of IFN-γ-chemokine through the JAK/STAT signaling pathway in immortalized human keratinocyte (HaCaT) cells .

HY-N0065

Eudesmol	Others	Neurological Disease
Eudesmol is a sesquiterpenoid compound produced by Streptomyces tendae .

HY-N9626

Cuparene (R)-Cuparene	Others	Others
Cuparene ((R)-Cuparene) is a sesquiterpenoid and can be isolated from Cupressaceae .

HY-N3537

Canusesnol A	Others	Others
Canusesnol A is a Sesquiterpenoids product that can be isolated from the herbs of Datura arborea .

HY-N3583

Chlorouvedalin	Others	Others
Chlorouvedalin is a Sesquiterpenoids product that can be isolated from the herbs of Smallanthus sonchifolius .

HY-N9209

Cinalbicol	Others	Others
Cinalbicol is a Sesquiterpenoids product that can be isolated from the roots of Cacalia roborowskii. .

HY-135444

Heliangin	NF-κB	Others
Heliangin is a Sesquiterpenoids product that can be isolated from the herbs of Helianthus tuberosus L. .

HY-N3840

Epoxyparvinolide	Others	Others
Epoxyparvinolide is a Sesquiterpenoids product that can be isolated from the herbs of Pogostemon parviflorus .

Cat. No.	Product Name	Category	Target	Chemical Structure