Search Result
Results for "
salt
" in MedChemExpress (MCE) Product Catalog:
15
Biochemical Assay Reagents
6
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-P6013A
-
|
|
Calcium Channel
|
Others
|
|
wt hMLN (TFA) is a microprotein that inhibits of SR Ca 2+ pump (SERCA). wt hMLN plays an important role in skeletal muscle calcium homeostasis .
|
-
-
- HY-P5815A
-
|
Glucagon-like Peptide 1 (1-36) amide (human, rat) (TFA)
|
GLP Receptor
GCGR
|
Metabolic Disease
|
|
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat)
) TFA is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) TFA can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells .
|
-
-
- HY-P10002A
-
-
-
- HY-P6010A
-
|
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Integrin
|
Cancer
|
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αvβ6-BP TFA is a selective αvβ6 binding peptide, and can be used for research of molecular imaging .
|
-
-
- HY-P10003A
-
-
-
- HY-P5201S1
-
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Isotope-Labeled Compounds
|
Others
|
|
VTSEGAGLQLQK- 13C6, 15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
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-
-
- HY-P6009A
-
|
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Integrin
|
Cancer
|
|
Cys-αvβ6-BP TFA is a cysteine-terminated αvβ6 binding peptide .
|
-
-
- HY-156344S1
-
-
-
- HY-156345S1
-
-
-
- HY-156343S1
-
-
-
- HY-156341S1
-
-
-
- HY-P1426A
-
|
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Potassium Channel
|
Inflammation/Immunology
|
|
AmmTX3 TFA is a peptide toxin that can be isolated from the venom of the scorpion Androctonus mauretanicus. AmmTX3 TFA is specific blocker of Kv4 channel. AmmTX3 TFA inhibits the A-type K + current (Ki: 131 nM) .
|
-
-
- HY-P0014S1
-
|
|
Isotope-Labeled Compounds
GLP Receptor
GCGR
|
Others
|
|
Liraglutide- 13C5, 15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
-
-
- HY-P1925A
-
|
|
PI3K
Reactive Oxygen Species (ROS)
Apoptosis
|
Cancer
|
|
GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .
|
-
-
- HY-105168
-
|
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Endothelin Receptor
|
Cardiovascular Disease
|
|
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
-
- HY-145632A
-
|
ALT-801 TFA
|
GLP Receptor
GCGR
|
Metabolic Disease
|
|
Pemvidutide (ALT-801) TFA is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide TFA can be used in non-alcoholic steatohepatitis (NASH) and obesity research .
|
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-
- HY-W094708C
-
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Disodium hydrogen phosphate dihydrate, for molecular biology
|
Biochemical Assay Reagents
|
Others
|
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Sodium phosphate dibasic dihydrate, for molecular biology is an inorganic salt compound. Sodium phosphate dibasic dihydrate, for molecular biology is commonly used in molecular biology experiments and can be used as a buffer, nutritional supplement, and detergent.
|
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- HY-B0895
-
-
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- HY-Y0406E
-
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Calcium dichloride anhydrous, for cell culture
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Biochemical Assay Reagents
|
Cancer
|
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Calcium chloride anhydrous, for cell culture is an inorganic salt for the preparation of various buffers . Calcium chloride anhydrous, for cell culture can be used for animal modeling, to construct abdominal aortic aneurysm models .
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- HY-Y0406H
-
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Calcium dichloride anhydrous, powder, 97%
|
Biochemical Assay Reagents
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Others
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Calcium chloride anhydrous, powder, 97% is an inorganic salt for the preparation of various buffers .
|
-
-
- HY-Y0319B2
-
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Potassium acetate (Pharmaceutical primary standard, USP)
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Biochemical Assay Reagents
|
Others
|
|
Potassium acetate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
-
- HY-Y0319G1
-
-
-
- HY-Y0344H
-
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Halite (Pharmaceutical primary standard, USP)
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Biochemical Assay Reagents
|
Others
Cancer
|
|
Sodium chloride, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
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- HY-W094708D
-
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Disodium hydrogen phosphate dihydrate, meets analytical specification of Ph. Eur. BP
|
Biochemical Assay Reagents
|
Others
|
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Sodium phosphate dibasic dihydrate, meets analytical specification of Ph. Eur. BP is an inorganic salt that can be used for life science related research .
|
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- HY-W019877
-
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Biochemical Assay Reagents
|
Metabolic Disease
|
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Sodium sulfate decahydrate is a ubiquitous salt that reaches toxic concentrations due to mining and other industrial activities. Sodium sulfate can be used to enhance the conjugation of phenolic drugs with sulfate and to treat hypercalcemia .
|
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- HY-109528
-
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ISIS-2922
|
CMV
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Infection
|
|
Fomivirsen (ISIS-2922) sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen sodium is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein, thus inhibiting virus proliferation .
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-
- HY-Y0308H
-
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Disodium hydrogen phosphate, for molecular biology
|
Biochemical Assay Reagents
|
Others
|
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Sodium phosphate dibasic, for molecular biology is an inorganic salt that can be used for life science related research .
|
-
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- HY-W094475E
-
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Epsom salts (Pharmaceutical primary standard, USP)
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Biochemical Assay Reagents
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Others
Cancer
|
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Magnesium sulfate heptahydrate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
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- HY-Y1325H
-
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Biochemical Assay Reagents
|
Others
|
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Sodium acetate trihydrate, meets analytical specification of Ph. Eur. BP USP FCC E262, ≤0.00002% Al is an inorganic salt that can be used for life science related research .
|
-
-
- HY-W438378
-
|
HMPG piperazine
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Biochemical Assay Reagents
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Others
|
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4-Hydroxy-3-methoxyphenylglycol piperazine (HMPG piperazine) is a salt of HMPG combined with piperazine. HMPG is a metabolite of adrenaline and norepinephrine and is an important marker of catecholamine hormone metabolism in the body. 4-Hydroxy-3-methoxyphenylglycol piperazine is used as a standard in clinical laboratories to accurately measure the HMPG content in urine .
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-
-
- HY-N2713
-
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Others
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Others
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10-Carboxylinalool is a metabolite compound isolated from the genus Pseudomonasin in a mineral salt medium .
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-
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- HY-Y1325E
-
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Sodium acetate trihydrate (Pharmaceutical primary standard, USP)
|
Biochemical Assay Reagents
|
Others
|
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Sodium acetate trihydrate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
-
- HY-132609
-
|
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Small Interfering RNA (siRNA)
Transthyretin (TTR)
|
Neurological Disease
|
|
Patisiran sodium is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. Patisiran sodium specifically inhibits hepatic synthesis of mutant and wild-type TTR. Patisiran sodium can be used for the research of hereditary TTR amyloidosis .
|
-
-
- HY-145722
-
|
OGX-427 sodium
|
HSP
|
Cancer
|
|
Apatorsen (sodium) is an antisense oligonucleotide designed to bind to Hsp27 mRNA, resulting in the inhibition of the production of Hsp27 protein.
|
-
-
- HY-105047
-
|
NRL972
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Fluorescein lisicol is a fluorescent-labelled bile salt and a marker of hepatic biliary transporter function. Fluorescein lisicol can be used for metabolic research .
|
-
-
- HY-W094710
-
|
Sodium hydrogen diacetate
|
Bacterial
|
Infection
|
|
Sodium diacetate (Acetic acid, sodium salt (2:1)) is a salt of acetic acid. Sodium diacetate is a colorless solid that is used in seasonings and as an antimicrobial agent. Sodium diacetate is used in the food additive extensively .
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-
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- HY-132608
-
|
ISIS-420915 sodium
|
Transthyretin (TTR)
|
Neurological Disease
|
|
Inotersen (ISIS-420915) sodium is a 2′-O-methoxyethyl-modified antisense oligonucleotide. Inotersen sodium inhibits the production of transthyretin (TTR) protein by targeting the TTR RNA transcript and reduces the levels of the TTR transcript. Inotersen sodium can be used for the research of hereditary TTR amyloidosis polyneuropathy .
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-
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- HY-108764
-
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ISIS 301012
|
Apolipoprotein
HCV
|
Metabolic Disease
|
|
Mipomersen sodium (ISIS 301012) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB). Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen sodium can be used for the research of homozygous familial hypercholesterolemia (HoFH) .
|
-
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- HY-Y1267D
-
-
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- HY-15790A
-
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A 3309 hydrate; AZD 7806 hydrate
|
Apical Sodium-Dependent Bile Acid Transporter
|
Metabolic Disease
Cancer
|
|
Elobixibat (A 3309; AZD 7806) hydrate is an orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat hydrate can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to treat metabolic syndrome. Elobixibat hydrate can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly .
|
-
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- HY-109561
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EYE001; NX1838
|
VEGFR
|
Metabolic Disease
Inflammation/Immunology
|
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Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) .
|
-
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- HY-Y0319B
-
|
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Endogenous Metabolite
|
Infection
|
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Acetic acid potassium 99% is a potassium salt employed to replenish electrolytes, for restoration of water-electrolyte balance. Acetic acid potassium 99% can employ in DNA and protein purification. Acetic acid potassium 99% has been used to prepare neutralizing solution for alkaline lysis of bacteria .
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- HY-160113
-
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Biochemical Assay Reagents
|
Others
|
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Sodium phosphate buffer (0.02 M, pH 6.9) is a water-based salt solution. Sodium phosphate buffer (0.02 M, pH 6.9) is a buffer solution commonly used in biological research.
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-
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- HY-132613
-
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Small Interfering RNA (siRNA)
|
Metabolic Disease
|
|
Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) .
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-
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- HY-147080
-
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ARC1905
|
Complement System
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Others
|
|
Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system. Avacincaptad pegol sodium treats Geographic atrophy (GA) mice .
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-
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- HY-135659
-
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Bacterial
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Infection
|
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BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs) with IC50s of 108 nM and 427 nM for B. longum BSH (Gram positive) and B. theta BSH (Gram negative), respectively .
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-
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- HY-148198
-
-
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- HY-147692
-
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COX
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Inflammation/Immunology
|
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COX-2-IN-14 (compound 2a) is a potent and selective COX-2 (cyclooxygenase-2) inhibitor. COX-2-IN-14 shows effective binding at the active site of COX-2 co-crystal. COX-2-IN-14 exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity in mice .
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-
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- HY-111974
-
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ABA-GE; (S)-cis,trans-Abscisic acid glucosyl ester
|
Proton Pump
|
Endocrinology
|
|
β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable abscisic acid (ABA) conjugate that accumulates in the vacuole and presumably also in the endoplasmic reticulum. The deconjugation of β-D-Glucopyranosyl abscisate allows the rapid formation of free ABA in response to abiotic stress conditions such as dehydration and salt stress. β-D-Glucopyranosyl abscisate contributes to the maintenance of ABA homeostasis .
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-
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- HY-W010860
-
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Biochemical Assay Reagents
|
Others
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|
Copper(II) Gluconate is a non-toxic copper supplement aid. Copper(II) Gluconate is the copper salt of D-gluconic acid. Copper(II) Gluconate as a precursor catalyst that can be used in the photo-induced polymerisation of acrylates .
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- HY-D0876
-
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Biochemical Assay Reagents
|
Others
|
|
POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5 .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W094708C
-
|
Disodium hydrogen phosphate dihydrate, for molecular biology
|
Buffer Reagents
|
|
Sodium phosphate dibasic dihydrate, for molecular biology is an inorganic salt compound. Sodium phosphate dibasic dihydrate, for molecular biology is commonly used in molecular biology experiments and can be used as a buffer, nutritional supplement, and detergent.
|
-
- HY-Y0406E
-
|
Calcium dichloride anhydrous, for cell culture
|
Buffer Reagents
|
|
Calcium chloride anhydrous, for cell culture is an inorganic salt for the preparation of various buffers . Calcium chloride anhydrous, for cell culture can be used for animal modeling, to construct abdominal aortic aneurysm models .
|
-
- HY-Y0406H
-
|
Calcium dichloride anhydrous, powder, 97%
|
Buffer Reagents
|
|
Calcium chloride anhydrous, powder, 97% is an inorganic salt for the preparation of various buffers .
|
-
- HY-Y1325H
-
|
|
Buffer Reagents
|
|
Sodium acetate trihydrate, meets analytical specification of Ph. Eur. BP USP FCC E262, ≤0.00002% Al is an inorganic salt that can be used for life science related research .
|
-
- HY-Y0319B2
-
|
Potassium acetate (Pharmaceutical primary standard, USP)
|
Buffer Reagents
|
|
Potassium acetate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
- HY-Y0319G1
-
|
|
Buffer Reagents
|
|
Magnesium acetate tetrahydrate, for molecular biology is an inorganic salt that can be used for molecular biology .
|
-
- HY-Y0344H
-
|
Halite (Pharmaceutical primary standard, USP)
|
Buffer Reagents
|
|
Sodium chloride, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
- HY-W094708D
-
|
Disodium hydrogen phosphate dihydrate, meets analytical specification of Ph. Eur. BP
|
Buffer Reagents
|
|
Sodium phosphate dibasic dihydrate, meets analytical specification of Ph. Eur. BP is an inorganic salt that can be used for life science related research .
|
-
- HY-Y0308H
-
|
Disodium hydrogen phosphate, for molecular biology
|
Buffer Reagents
|
|
Sodium phosphate dibasic, for molecular biology is an inorganic salt that can be used for life science related research .
|
-
- HY-W094475E
-
|
Epsom salts (Pharmaceutical primary standard, USP)
|
Buffer Reagents
|
|
Magnesium sulfate heptahydrate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
- HY-Y1325E
-
|
Sodium acetate trihydrate (Pharmaceutical primary standard, USP)
|
Buffer Reagents
|
|
Sodium acetate trihydrate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
- HY-Y1267D
-
|
|
Buffer Reagents
|
|
Magnesium sulfate, for cell culture is a bioreagent. Magnesium sulfate is a calcium antagonist and a potent L-type calcium channel inhibitor, as well as a tocolytic. Magnesium sulfate has anti-inflammatory, anticonvulsant, vasodilatory, and neuroprotective effects. Magnesium sulfate can be used in the research of diseases such as preeclampsia/eclampsia .
|
-
- HY-Y0319B
-
|
|
Buffer Reagents
|
|
Acetic acid potassium 99% is a potassium salt employed to replenish electrolytes, for restoration of water-electrolyte balance. Acetic acid potassium 99% can employ in DNA and protein purification. Acetic acid potassium 99% has been used to prepare neutralizing solution for alkaline lysis of bacteria .
|
-
- HY-160113
-
|
|
Buffer Reagents
|
|
Sodium phosphate buffer (0.02 M, pH 6.9) is a water-based salt solution. Sodium phosphate buffer (0.02 M, pH 6.9) is a buffer solution commonly used in biological research.
|
-
- HY-D0876
-
|
|
Buffer Reagents
|
|
POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5 .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P6013A
-
|
|
Calcium Channel
|
Others
|
|
wt hMLN (TFA) is a microprotein that inhibits of SR Ca 2+ pump (SERCA). wt hMLN plays an important role in skeletal muscle calcium homeostasis .
|
-
- HY-P5815A
-
|
Glucagon-like Peptide 1 (1-36) amide (human, rat) (TFA)
|
GLP Receptor
GCGR
|
Metabolic Disease
|
|
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat)
) TFA is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) TFA can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells .
|
-
- HY-P2512A
-
|
|
Peptides
|
Others
|
|
Phytochelatin 2 (PC2) TFA is a phytochelatin, an important heavy metal-binding peptide. Phytochelatin 2 (PC2) TFA can chelate metals, prevent metal toxicity, and maintain metal stability in the internal environment .
|
-
- HY-P10002A
-
-
- HY-P6010A
-
|
|
Integrin
|
Cancer
|
|
αvβ6-BP TFA is a selective αvβ6 binding peptide, and can be used for research of molecular imaging .
|
-
- HY-P10003A
-
-
- HY-P5201S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
VTSEGAGLQLQK- 13C6, 15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
|
-
- HY-P6009A
-
|
|
Integrin
|
Cancer
|
|
Cys-αvβ6-BP TFA is a cysteine-terminated αvβ6 binding peptide .
|
-
- HY-156344S1
-
-
- HY-156345S1
-
-
- HY-156343S1
-
-
- HY-156341S1
-
-
- HY-P1426A
-
|
|
Potassium Channel
|
Inflammation/Immunology
|
|
AmmTX3 TFA is a peptide toxin that can be isolated from the venom of the scorpion Androctonus mauretanicus. AmmTX3 TFA is specific blocker of Kv4 channel. AmmTX3 TFA inhibits the A-type K + current (Ki: 131 nM) .
|
-
- HY-P0014S1
-
|
|
Isotope-Labeled Compounds
GLP Receptor
GCGR
|
Others
|
|
Liraglutide- 13C5, 15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
-
- HY-P1925A
-
|
|
PI3K
Reactive Oxygen Species (ROS)
Apoptosis
|
Cancer
|
|
GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .
|
-
- HY-105168
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
- HY-145632A
-
|
ALT-801 TFA
|
GLP Receptor
GCGR
|
Metabolic Disease
|
|
Pemvidutide (ALT-801) TFA is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide TFA can be used in non-alcoholic steatohepatitis (NASH) and obesity research .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-P0014S1
-
|
|
|
Liraglutide- 13C5, 15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
-
-
- HY-P5201S1
-
|
|
|
VTSEGAGLQLQK- 13C6, 15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
|
-
-
- HY-156344S1
-
|
|
|
GLEWVAEIR-(Arg- 13C6, 15N4) (TFA) is the peptide containing 13C- and 15N-labeled Arg.
|
-
-
- HY-156345S1
-
|
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LPFTFGQGTK-(Lys- 13C6, 15N2) TFA is the peptide containing 13C- and 15N-labeled Lys.
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- HY-156343S1
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SNNYATHYAESVK-(Lys- 13C6, 15N2) (TFA) is the peptide containing 13C- and 15N-labeled Lys.
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- HY-156341S1
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LLIYYTSSLHSGVPSR-(Arg- 13C6, 15N4) (TFA) is the peptide containing 13C- and 15N-labeled Arg.
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| Cat. No. |
Product Name |
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Classification |
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- HY-109528
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ISIS-2922
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Antisense Oligonucleotides
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Fomivirsen (ISIS-2922) sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen sodium is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein, thus inhibiting virus proliferation .
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- HY-132609
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siRNAs
siRNA drugs
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Patisiran sodium is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. Patisiran sodium specifically inhibits hepatic synthesis of mutant and wild-type TTR. Patisiran sodium can be used for the research of hereditary TTR amyloidosis .
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- HY-145722
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OGX-427 sodium
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Antisense Oligonucleotides
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Apatorsen (sodium) is an antisense oligonucleotide designed to bind to Hsp27 mRNA, resulting in the inhibition of the production of Hsp27 protein.
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- HY-132608
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ISIS-420915 sodium
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Antisense Oligonucleotides
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Inotersen (ISIS-420915) sodium is a 2′-O-methoxyethyl-modified antisense oligonucleotide. Inotersen sodium inhibits the production of transthyretin (TTR) protein by targeting the TTR RNA transcript and reduces the levels of the TTR transcript. Inotersen sodium can be used for the research of hereditary TTR amyloidosis polyneuropathy .
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- HY-108764
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ISIS 301012
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Antisense Oligonucleotides
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Mipomersen sodium (ISIS 301012) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB). Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen sodium can be used for the research of homozygous familial hypercholesterolemia (HoFH) .
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- HY-145725
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IONIS 598769 sodium; ISIS 598769 sodium
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Antisense Oligonucleotides
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Baliforsen (sodium) is an antisense oligonucleotide (16 nucleotides) designed to target myotonic dystrophy protein kinase (DMPK) mRNA and research myotonic dystrophy.
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- HY-109561
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EYE001; NX1838
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Aptamers
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Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) .
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- HY-132613
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siRNAs
siRNA drugs
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Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) .
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- HY-147080
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ARC1905
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Aptamers
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Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system. Avacincaptad pegol sodium treats Geographic atrophy (GA) mice .
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