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peptide chain

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2511
    Insulin β Chain Peptide (15-23)

    		Transmembrane Glycoprotein Metabolic Disease
    Insulin β Chain Peptide (15-23) is one of the earliest antigenic epitopes to which CD8 T-cells respond .
    Insulin β Chain Peptide (15-23)
  • HY-A0162
    Quinupristin
    1 Publications Verification

    		 Bacterial Infection
    Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .
    Quinupristin
  • HY-P10346
    smMLCK peptide

    Smooth-Muscle Myosin Light-chain Kinase (796-815)

    		 Myosin Cardiovascular Disease Inflammation/Immunology
    smMLCK peptide is a specific inhibitor of smooth muscle myosin light chain kinase (smMLCK). The smMLCK peptide mimics the substrate and competitively inhibits the binding of the actual substrate to the enzyme, thereby inhibiting the kinase activity. This inhibition prevents the phosphorylation of the myosin light chain, thus inhibiting muscle contraction .
    smMLCK peptide
  • HY-P2981
    Carboxypeptidase C

    Carboxypeptidase Y; EC 3.4.16.1

    		 Carboxypeptidase Others
    Carboxypeptidase C is a carboxypeptidase, is often used in biochemical studies. Carboxypeptidase C removes COOH-terminal lysine, arginine, and proline, as well as all other neutral, aliphatic, aromatic, and the acidic protein amino acids of a peptide chain .
    Carboxypeptidase C
  • HY-P10628
    β Amyloid (1-14), human

    		Amyloid-β Neurological Disease
    β Amyloid (1-14), human is a peptide fragment of β-amyloid protein (Aβ), which is obtained by hydrolysis of Aβ1-40 peptide by catalytic antibody light chain #7TR. β Amyloid (1-14), human can be used for Alzheimer's disease research .
    β Amyloid (1-14), human
  • HY-P5998
    Myosin Light Chain Kinase Substrate (smooth muscle)

    		Myosin Cancer
    Myosin Light Chain Kinase Substrate (smooth muscle) is a smooth muscle myosin light chain kinase (MLCK) synthetic peptide substrate .
    Myosin Light Chain Kinase Substrate (smooth muscle)
  • HY-P1512
    Antioxidant peptide A

    		SOD Cancer
    Antioxidant peptide A is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell.
    Antioxidant peptide A
  • HY-P2162
    Kemptamide

    		Myosin Cancer
    Kemptamide, a 13 amino acid fragment with a sequence corresponding to residues 11-23 of gizzard light chain. Kemptamide is a peptide substrate of myosin light-chain kinase (MLCK) .
    Kemptamide
  • HY-A0162A
    Quinupristin mesylate

    		Bacterial Infection
    Quinupristin mesylate is a streptogramin antibiotic. Quinupristin mesylate blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .
    Quinupristin mesylate
  • HY-P10165
    MLCK Peptide

    		Calmodulin Metabolic Disease
    MLCK Peptide is a fully reversible, high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase .
    MLCK Peptide
  • HY-P1826
    CLIP (86-100)

    		CD74 Inflammation/Immunology Cancer
    CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site .
    CLIP (86-100)
  • HY-P0318
    Hemorphin-7

    		Opioid Receptor Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE).
    Hemorphin-7
  • HY-Z11724
    Semaglutide Main Chain (9-37)

    		Drug Derivative Metabolic Disease
    Semaglutide Main Chain (9-37) is a peptide starting material in the synthesis of semaglutide (HY-114118) .
    Semaglutide Main Chain (9-37)
  • HY-P1856
    Proinsulin C-peptide (human)

    		Insulin Receptor Metabolic Disease
    Proinsulin C-peptide (human) is a 31-amino-acid peptide that links the A and B chains of proinsulin, ensuring its correct folding, which is biologically active and modulates cellular function .
    Proinsulin C-peptide (human)
  • HY-P10516
    BRC4 peptide

    		DNA/RNA Synthesis RAD51 Cancer
    BRC4 peptide is a specific peptide in BRCA2 protein that interacts with RAD51 protein to help repair broken DNA chains. BRC4 peptide can be used to study DNA repair mechanisms and cancer occurrence .
    BRC4 peptide
  • HY-P1805
    Calmodulin Binding Peptide 1

    		Calmodulin Neurological Disease
    Calmodulin Binding Peptide 1 is a high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase (MLCK peptide), which strongly inhibits IP3-induced Ca 2+ release .
    Calmodulin Binding Peptide 1
  • HY-P1493
    Fibrinopeptide B, human

    FPB,human

    		 Thrombin Inflammation/Immunology
    Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.
    Fibrinopeptide B, human
  • HY-139276
    Pal-Glu(OSu)-OH

    		GLP Receptor Others
    Pal-Glu(OSu)-OH is a side chain of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used for type 2 diabetes mellitus research .
    Pal-Glu(OSu)-OH
  • HY-P0181
    Microtubule-associated protein tau (26-44)

    		Tau Protein Neurological Disease
    Microtubule-associated protein tau (26-44) is a synthetic peptide chain with an amine group attached to glutamine and an carboxyl group attached to lysine.
    Microtubule-associated protein tau (26-44)
  • HY-164166
    Fmoc-Sar-Sar-Sar-OH

    		Biochemical Assay Reagents Others
    Fmoc-Sar-Sar-Sar-OH is a small molecule polypeptide composed of four sarcosine residues, in which the N-terminus of the peptide chain is protected by Fmoc. Fmoc-Sar-Sar-Sar-OH can be used for peptide synthesis or synthesis of drug-peptide ligand conjugates .
    Fmoc-Sar-Sar-Sar-OH
  • HY-W048209
    Fmoc-Lys(Palmitoyl)-OH

    		Amino Acid Derivatives Others
    Fmoc-Lys(Palmitoyl)-OH is a Fmoc-amino acid with long alkyl chains. Fmoc-Lys(Palmitoyl)-OH can be used for peptide synthesis .
    Fmoc-Lys(Palmitoyl)-OH
  • HY-P2746
    Carboxypeptidase B, Porcine pancreas

    EC 3.4.2.2

    		 Endogenous Metabolite Metabolic Disease
    Carboxypeptidase B, Porcine pancreas (EC 3.4.2.2) is a peptide exonuclease that can specifically degrade peptide chains. Carboxypeptidase B is progressively degraded from the C-terminal to release free amino acids. Carboxypeptidase B hydrolyzes only peptide bonds with basic amino acids (such as arginine and lysine) as C-terminal residues .
    Carboxypeptidase B, Porcine pancreas
  • HY-P5444
    Drosocin

    		Bacterial Others
    Drosocin is a biological active peptide. (Drosocin is a 19-mer cationic antimicrobial peptide from Drosophila melanogaster. In Drosophila native drosocin carries a disaccharide moiety attached to a threonine residue in mid-chain position. This synthetic drosocin peptide of identical amino acid sequence without the disaccharide has an activity several times lower than the native compound.)
    Drosocin
  • HY-E70201
    Carboxypeptidase B (MS grade)

    EC 3.4.2.2 (MS grade)

    		 Endogenous Metabolite Others
    Carboxypeptidase B (MS grade) is a peptide exonuclease that can specifically degrade peptide chains. Carboxypeptidase B (MS grade) is progressively degraded from the C-terminal to release free amino acids. Carboxypeptidase B (MS grade) hydrolyzes only peptide bonds with basic amino acids (such as arginine and lysine) as C-terminal residues .
    Carboxypeptidase B (MS grade)
  • HY-W717830
    CB-Cyclam

    		Biochemical Assay Reagents Others
    CB-Cyclamis a bifunctional chelator (Bifunctional Chelator; BFC), which is a main chain Cyclen derivative of the macrocyclic ligand tetradecane. CB-Cyclam can be used for conjugation of peptides and radionuclides.
    CB-Cyclam
  • HY-P4043
    Hepatitis b virus pre-s region (120-145)

    		HBV Infection Inflammation/Immunology
    Hepatitis b virus pre-s region (120-145) is a preS2 peptide that inhibits the binding of single-chain Fv fragment (scFv) or IgG to r-HBsAg .
    Hepatitis b virus pre-s region (120-145)
  • HY-P1029
    MLCK inhibitor peptide 18
    4 Publications Verification

    		 Myosin CaMK Autophagy Others
    MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.
    MLCK inhibitor peptide 18
  • HY-P1507
    Fibrinogen Binding Inhibitor Peptide

    		Integrin Cardiovascular Disease
    Fibrinogen Binding Inhibitor Peptide is a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen γ-chain carboxy-terminal sequence (γ400-411). Fibrinogen Binding Inhibitor Peptide is a specific binding site of the ligand for activated glycoprotein (GP) IIb/IIIa.
    Fibrinogen Binding Inhibitor Peptide
  • HY-145263
    VD2173

    		Ser/Thr Protease Cancer
    VD2173 is a side chain cyclized macrocyclic peptide inhibitor of HGF-activating serine proteases. VD2173 potently inhibits matriptase and hepsin. VD2173 can be used for the research of lung cancer .
    VD2173
  • HY-116010
    Oleandomycin
    1 Publications Verification

    		 Bacterial Antibiotic Infection
    Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes .
    Oleandomycin
  • HY-116010A
    Oleandomycin phosphate

    		Antibiotic Bacterial Infection
    Oleandomycin phosphate is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes .
    Oleandomycin phosphate
  • HY-P5723
    Api137

    		Bacterial Infection
    Api137 is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain .
    Api137
  • HY-P1195
    PDZ1 Domain inhibitor peptide

    		iGluR Neurological Disease
    PDZ1 Domain inhibitor peptide, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain .
    PDZ1 Domain inhibitor peptide
  • HY-P10722
    Efpegerglucagon

    HM15136

    		 GCGR Inflammation/Immunology
    Efpegerglucagon is an Fc fragment of human immunoglobulin G4 (IgG4), formed as a disulfide-bonded dimer. One of the Fc chains is linked via a bifunctional maleimide-polyethylene glycol-aldehyde linker to a glucagon peptide analogue .
    Efpegerglucagon
  • HY-P5723A
    Api137 TFA

    		Bacterial Infection
    Api137 TFA is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 TFA inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain .
    Api137 TFA
  • HY-P1195A
    PDZ1 Domain inhibitor peptide TFA

    		iGluR Neurological Disease
    PDZ1 Domain inhibitor peptide TFA, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide TFA disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain .
    PDZ1 Domain inhibitor peptide TFA
  • HY-79647
    Fmoc-OSu

    N-(Fmoc-oxy)succinimide

    		 Biochemical Assay Reagents Others
    Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .
    Fmoc-OSu
  • HY-P2230
    Angstrom6

    A6 peptide

    		 PAI-1 Cancer
    Angstrom6 (A6 Peptide) is an 8 amino-acid peptide derived from single-chain urokinase plasminogen activator (scuPA) and interferes with the uPA/uPAR cascade and abrogates downstream effects. Angstrom6 binds to CD44 resulting in the inhibition of migration, invasion, and metastasis of tumor cells, and the modulation of CD44-mediated cell signaling .
    Angstrom6
  • HY-147835
    Antibacterial agent 109

    		Bacterial Infection
    Antibacterial agent 109 (Compound C-2) is a potent antibacterial agent against both gram-positive and gram negative bacteria, and non-mutagenic. Antibacterial agent 109 inhibits protein synthesis by blocking the extension of new peptide chains .
    Antibacterial agent 109
  • HY-137870
    γ-Glutamyl-β-naphthylamide

    gamma-Glutamyl-beta-naphthylamide

    		 Biochemical Assay Reagents Others
    γ-Glutamyl-β-naphthylamide is a substrate for γ-glutamine peptidase. γ-Glutamyl-β-naphthylamide is specifically recognized and the peptide chain is cleaved. γ-Glutamyl-β-naphthylamide can be used to distinguish between gonococci and meningococci .
    γ-Glutamyl-β-naphthylamide
  • HY-124129
    10074-A4

    		c-Myc Cancer
    10074-A4 is a c-Myc inhibitor. 10074-A4 could bind to c-Myc370-409 at different sites along the peptide chain. 10074-A4 has anticancer effects .
    10074-A4
  • HY-106275
    FX-06

    Fibrin-derived peptide Bβ15-42

    		 Flavivirus Dengue Virus Cardiovascular Disease
    FX-06 (Fibrin-derived peptide Bβ15-42) is a fibrin Bbeta chain-derived peptide. FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling. FX-06 can be used in the research of ischemia/reperfusion injury, Dengue shock syndrome (DSS) .
    FX-06
  • HY-P1745
    InsB (9-23)

    Insulin B chain (9-23)

    		 MHC Inflammation/Immunology
    InsB (9-23) is an insulin B-chain peptide that binds to a class II histocompatibility complex (MHC) allele called I-Ag7. InsB (9-23) can be used to treat a number of autoimmune related diseases like Type 1 diabetes .
    InsB (9-23)
  • HY-P2980
    Carboxypeptidase A, Bovine pancreas

    EC 3.4.2.1

    		 Endogenous Metabolite Others
    Carboxypeptidase A, Bovine pancreas (EC 3.4.2.1) is a zinc-containing metalloprotease, is often used in biochemical studies. Carboxypeptidase A catalyzes the hydrolysis of the peptide bonds that are adjacent to the C-terminal end of a polypeptide chain. Carboxypeptidase A is a prototypical enzyme for metalloproteases that plays important roles in biological systems .
    Carboxypeptidase A, Bovine pancreas
  • HY-P990088
    Sotiburafusp alfa

    		VEGFR PD-1/PD-L1 Cardiovascular Disease
    Sotiburafusp alfa is a bispecific fusion protein, which is a humanized VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) fused via the peptide linker 101GGSGGSGGSGGSGGS 115 to the N-terminus of the heavy chain (116-564) of a humanized IgG1-kappa anti-human PD-L1 heavy chain variant L352>A, L353>A. Sotiburafusp alfa is also an angiogenesis inhibitor .
    Sotiburafusp alfa
  • HY-P5807A
    Cn2 toxin TFA

    β-Mammal toxin Cn2 TFA

    		 Sodium Channel Neurological Disease
    Cn2 toxin TFA (β-Mammal toxin Cn2 TFA) is a single-chain β-scorpion neurotoxic peptide that is the main toxin in scorpion venom. Cn2 toxin (TFA) specifically targets mammalian voltage-gated sodium channels (VGSC) Nav1.6 .
    Cn2 toxin TFA
  • HY-P10536
    Temporin SHF

    		Bacterial Infection
    Temporin SHF is a broad-spectrum antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria and yeasts, but does not have hemolytic activity. Temporin SHF disrupts the acyl chain stacking of anionic lipid bilayers, leading to cracks and disintegration of microbial membranes. Temporin SHF can be used in the development of antimicrobial drugs .
    Temporin SHF
  • HY-P2834
    Penicillin amidase, E. coli

    PGA

    		 Biochemical Assay Reagents Infection Cancer
    Penicillin amidase (EC 3.5.1.11) (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins. Penicillin amidase can be used for the production of 6-aminopenicillanic acid. Penicillin amidase can also be used in the resolution of racemic mixtures, peptide synthesis, and synthesis of semi-synthetic β-lactam antibiotics .
    Penicillin amidase, E. coli
  • HY-131618
    Hippuryl-Arg

    Bz-Gly-Arg

    		 Amino Acid Derivatives Others
    Hippuryl-Arg (Bz-Gly-Arg) is a substrate used for fluorescence detection and is commonly used in biochemical studies, especially in studying enzyme activity. The phenylalanine portion of Hippuryl-Arg is connected by an aromatic side chain, which allows it to be detected under ultraviolet light. Hippuryl-Arg is used to detect enzymes that recognize and cut peptide bonds containing arginine .
    Hippuryl-Arg
  • HY-130656
    8(Z)-Eicosenoic acid

    cis-8-Eicosenoic acid

    		 Endogenous Metabolite Metabolic Disease
    8(Z)-Eicosenoic acid is a cis-unsaturated free fatty acid with a 20-carbon chain. It potentiates acetylcholine (ACh) receptor channel currents without depression and enhances PCKε phosphorylation of a substrate peptide in Xenopus oocytes. 8(Z)-Eicosenoic acid constitutes 6% of the fatty acid pool in seed oil isolated from B. collina.
    8(Z)-Eicosenoic acid

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