Search Result
Results for "
para
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
9
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-111474
-
|
Myosin
|
Cardiovascular Disease
Neurological Disease
|
Para-aminoblebbistatin is the inhibitor for myosin II. Para-aminoblebbistatin inhibits the ATPase activity of myosin II, thereby blocking the formation and contraction of the actin-myosin network. Para-aminoblebbistatin is a non-fluorescent and photostable Blebbistatin (HY-13813) derivative .
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-
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- HY-165831
-
-
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- HY-120870
-
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Myosin
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Metabolic Disease
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para-Nitroblebbistatin is a derivative of Blebbistatin (HY-13813) and an inhibitor of myosin II. para-Nitroblebbistatin is photostable, non-cytotoxic, and non-phototoxic. para-Nitroblebbistatin can serve as an ideal substitute for Blebbistatin (HY-13813) to study the role of myosin II in physiology, development, and cell biology .
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-
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- HY-165836
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-
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- HY-W750432
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-
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- HY-W588258S1
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-
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- HY-W739835
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- HY-W681674
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-
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- HY-139388
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-
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- HY-G0005
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para-Naphthol duloxetine
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Drug Metabolite
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Neurological Disease
|
Para-Naphthol Duloxetine is a metabolite of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor (SNRI).
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-
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- HY-W399538
-
-
-
- HY-15632
-
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Fluorescent Dye
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Others
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para-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .
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- HY-118380
-
4-Nitrobenzyl mesylate; para-Nitrobenzyl mesylate; PNBM
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Biochemical Assay Reagents
|
Metabolic Disease
|
p-Nitrobenzyl mesylate (4-Nitrobenzyl mesylate; para-Nitrobenzyl mesylate) is a reagent used to alkylate phosphorothioates, forming phosphorothioate epitopes that can be recognized by specific antibodies.
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-
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- HY-170054
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p-Fluoro 4-ANBP; Despropionyl N-benzyl p-fluoro norfentanyl
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Drug Intermediate
|
Neurological Disease
|
Para-fluoro 4-ANBP (p-Fluoro 4-ANBP) is a precursor in the synthesis of Fluoroketamine.
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- HY-D1045
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DABCYL; para-methyl red
|
Fluorescent Dye
|
Others
|
Dabcyl acid (Dabcyl) is a nonfluorescent chromophore and a quencher. Dabcyl acid can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
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- HY-D1045A
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DABCYL sodium; para-methyl red sodium
|
Fluorescent Dye
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Others
|
Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
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-
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- HY-18775
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para-topolin riboside
|
P2Y Receptor
|
Cardiovascular Disease
|
N6-(4-Hydroxybenzyl)adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM).
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-
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- HY-Y1630S
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para-fluoronitrobenzene-d4; p-Fluoronitrobenzene-d4; p-Nitrofluorobenzene-d4
|
Isotope-Labeled Compounds
|
Others
|
NSC 10281-d4 is the deuterium labeled NSC 10281 .
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-
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- HY-W145693
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-
-
- HY-W909314
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Biochemical Assay Reagents
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Others
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t-Butyoxycarboxy-PEG4-para-nitrophenyl carbonate is a PEG linker with a nitrophenyl group linked to a carbonate, four PEG units, and a t-butyl group that can be deprotected under acidic conditions. The PEG units enhance the solubility of the molecule in aqueous media. Nitrophenyl group is reactive towards the amino-bearing molecules.
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- HY-D2286
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Fluorescent Dye
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Others
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HBT-Fl-BnB is a fluorescent probe for the ratiometric detection of ONOO - in vitro and in vivo. HBT-Fl-BnB consists of an HBT core with Fl groups at the ortho and para positions responding to the zwitterionic excited-state intramolecular proton-transfer (zwitterionic ESIPT) process and a boronic acid pinacol ester with dual roles that block the zwitterionic ESIPT and recognize ONOO - .
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- HY-155336
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- HY-117289
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- HY-135022
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-
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- HY-W707126
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- HY-172062
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-
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- HY-106685
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CI 935
|
Influenza Virus
|
Infection
|
Selenazofurin is an antiviral compound used against influenza A and influenza B viruses. Selenazofurin shows antiviral activity in cells against Measles, Para-3, Mumps, VV, HSV-2 with the ED50s of 3.7 μg/ml, 1.3 μg/ml, 8.0 μg/ml, 3.4 μg/ml, 4.3 μg/ml .
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- HY-W720313
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Drug Derivative
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Neurological Disease
|
4-Methyl-α-ethylaminobutiophenone hydrochloride is a para-methyl analog of buphedrone with an ethyl group replacing methyl at the alpha position.
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-
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- HY-D1199
-
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P2X Receptor
P2Y Receptor
|
Inflammation/Immunology
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Blue FPG-A trisodium is a selective antagonist of P2X1 receptor and P2Y1 receptor with IC50 values of 35.5 μM and 2.6 μM, respectively. Blue FPG-A trisodium is a structural isomer of the components of Reactive Blue 2 (RB2) .
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-
-
- HY-N2982
-
|
Influenza Virus
|
Infection
|
Caesalmin E is a natural cassane furanoditerpene with anti-Para3 (Parainfluenza virus type 3) virus activities .
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-
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- HY-W007614
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3-Fluoro-para-anisaldehyde
|
Biochemical Assay Reagents
|
Others
|
3-Fluoro-4-methoxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-P10668
-
|
Dengue Virus
Flavivirus
|
Infection
|
Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
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-
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- HY-162297
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Drug Metabolite
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Others
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4-(Sulfooxy)benzoic acid is a sulfated phenolic acid found in C. elegans. 4-(Sulfooxy)benzoic acid is a metabolite of ethyl para-hydroxybenzoate and several flavonoids .
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-
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- HY-W643129
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Drug Derivative
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Others
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1-(3,5-Di-tert-butyl-4-hydroxyphenyl)ethane-1,2-diol is a sterically hindered para-alkylphenol.
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-
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- HY-B0512S
-
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Isotope-Labeled Compounds
Bacterial
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Infection
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Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine, a sulfonamide antibacterial, inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes .
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-
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- HY-W134422
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Polyoxyethylene octylphenol ether
|
Biochemical Assay Reagents
|
Others
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(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene?glycol X-114 is a complex of three molecules formed by ortho-, meta-, and para-substitution of the benzene ring.
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-
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- HY-131556
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p-Iodoamphetamine hydrochloride
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5-HT Receptor
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Neurological Disease
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4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated amphetamine featuring an iodine atom at the para position of the phenyl group. 4-Iodoamphetamine hydrochloride selectively induces serotonin release and inhibits reuptake by rat brain synaptosomes.
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-
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- HY-76547S2
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4-Methylbenzoic acid-d3
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Endogenous Metabolite
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Others
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p-Toluic acid-d3 is the deuterium labeled p-Toluic acid . p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
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- HY-76547S
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4-Methylbenzoic acid-d4
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Endogenous Metabolite
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Others
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p-Toluic acid-d4 is the deuterium labeled p-Toluic acid . p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
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-
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- HY-147808
-
|
CXCR
HIV
|
Infection
Inflammation/Immunology
Cancer
|
CXCR4 antagonist 7 (Compound PARA-B) is a CXCR4 antagonist with the IC50 of 9.3 nM. CXCR4 antagonist 7 can be used for the research of HIV infection, inflammatory diseases, cancer, and WHIM syndrome .
|
-
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- HY-76547S1
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4-Methylbenzoic acid-d7
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Endogenous Metabolite
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Others
|
p-Toluic acid-d7 is the deuterium labeled p-Toluic acid . p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
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- HY-157370
-
|
Biochemical Assay Reagents
|
Others
|
Blood Enrichment Medium can be used for enrichment culture of pathogenic bacteria in blood. Blood Enrichment Medium ingredients include peptone, beef extract powder, NaCl, glucose, sodium citrate, para-aminobenzoic acid, magnesium sulfate, phenol red .
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-
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- HY-108069
-
|
Potassium Channel
nAChR
|
Neurological Disease
|
Iptakalim hydrochloride, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist .
|
-
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- HY-129051
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CGP4540
|
Parasite
Oxidative Phosphorylation
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Others
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Amoscanate (cgp4540) is phenyl isothiocyanate in which the hydrogen at the para-position has been replaced by a 4-nitroanilinyl group. Amoscanate is an anti-schistosomal agent. Amoscanate, as an isothiocyanate compound and uncoupler of oxidative phosphorylation, potently injures rodent ependyma .
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-
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- HY-143452
-
|
Tyrosinase
Bacterial
|
Inflammation/Immunology
|
MtTMPK-IN-4 (compound 2), a para-piperidine, is a potent mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 of 6.1 μM. MtTMPK-IN-4 is a potent tyrosinase inhibitor. MtTMPK-IN-4 is a potent antibacterial agent .
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-
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- HY-124296
-
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5-HT Receptor
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Neurological Disease
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2C-TFM hydrochloride is a ,5-dimethoxyphenethylamines compound with a para-trifluoromethyl substitution. 2C-TFM hydrochloride is a potent agonist of the 5-HT receptor subtypes 5-HT2A and 5-HT2C .
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-
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- HY-161084
-
|
c-Fms
|
Neurological Disease
Cancer
|
CSF1R-IN-18 (Compdound 16t), para-aniline derivative, is a colony-stimulating factor 1 receptor (CSF1R) inhibitor. CSF1R-IN-18 can be used for the research of cancers, CNS-diseases and bone diseases .
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-
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- HY-156031
-
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Cholinesterase (ChE)
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Neurological Disease
|
BChE-IN-19 (Compound 7b) is a para-substituted derivative of indone (7b) with inhibitory activity of butyryl cholinesterase (BChE) (IC50=0.04 μM). BChE-IN-19 improves cholinergic scheduling in the nervous system. BChE-IN-19 can be used against Alzheimer's disease .
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-
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- HY-B0512S1
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RP2632-13C6
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
Sulfamerazine- 13C6 (RP2632- 13C6) is 13C labeled Sulfamerazine (HY-B0512). Sulfamerazine (RP-2632) is a sulfonamide antibacterial. Sulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes.
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-
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- HY-N10800
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1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione
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Others
|
Cancer
|
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione is a kind of chemical constituents of Salvia miltiorrhiza f. alba. The dihydroisotanshinone with a para-quinone moiety shows cytotoxicity and anti-tumor activity .
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- HY-N7123
-
Sulphacetamide
|
Antibiotic
Bacterial
Fungal
|
Infection
Inflammation/Immunology
|
Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections .
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-
- HY-N7123R
-
Sulphacetamide (Standard)
|
Reference Standards
Antibiotic
Bacterial
Fungal
|
Infection
Inflammation/Immunology
|
Sulfacetamide (Standard) (Sulphacetamide (Standard)) is the analytical standard of Sulfacetamide (HY-N7123). This product is intended for research and analytical applications. Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections .
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-
- HY-155817
-
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Histone Methyltransferase
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Others
|
UNC7096 (compound 53) is a biotinylated affinity reagent. The phenyl ring of UNC7096 replaces the pyrimidine ring in UNC6934 (HY-145103) and introduces biotin at the para position of the phenyl ring, which has a high binding affinity to the NSD2-PWWP1 domain (Kd=46 nM). UNC7096 blocks the interaction between NSD2-PWWP1 and nucleosomal H3K36me2 by occupying the methyl-lysine binding pocket of NSD2-PWWP1. This binding is achieved by covalent binding through the formation of hydrogen bonds and a specific aromatic cage structure. UNC7096 can be used to capture proteins that interact with the NSD2-PWWP1 domain to further analyze the biological significance of these interactions .
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-
Cat. No. |
Product Name |
Type |
-
- HY-15632
-
|
DNA Stain
|
para-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .
|
-
- HY-D1045
-
DABCYL; para-methyl red
|
Fluorescent Dyes/Probes
|
Dabcyl acid (Dabcyl) is a nonfluorescent chromophore and a quencher. Dabcyl acid can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
|
-
- HY-D1045A
-
DABCYL sodium; para-methyl red sodium
|
Fluorescent Dyes/Probes
|
Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
|
-
- HY-D2286
-
|
Fluorescent Dyes/Probes
|
HBT-Fl-BnB is a fluorescent probe for the ratiometric detection of ONOO - in vitro and in vivo. HBT-Fl-BnB consists of an HBT core with Fl groups at the ortho and para positions responding to the zwitterionic excited-state intramolecular proton-transfer (zwitterionic ESIPT) process and a boronic acid pinacol ester with dual roles that block the zwitterionic ESIPT and recognize ONOO - .
|
Cat. No. |
Product Name |
Type |
-
- HY-W007614
-
3-Fluoro-para-anisaldehyde
|
Biochemical Assay Reagents
|
3-Fluoro-4-methoxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W134422
-
Polyoxyethylene octylphenol ether
|
Surfactants
|
(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene?glycol X-114 is a complex of three molecules formed by ortho-, meta-, and para-substitution of the benzene ring.
|
-
- HY-W145693
-
|
Biochemical Assay Reagents
|
Difucosyl-para-lacto-N-hexaose II (DFpLNH II) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-157370
-
|
Microbial Culture
|
Blood Enrichment Medium can be used for enrichment culture of pathogenic bacteria in blood. Blood Enrichment Medium ingredients include peptone, beef extract powder, NaCl, glucose, sodium citrate, para-aminobenzoic acid, magnesium sulfate, phenol red .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10668
-
|
Dengue Virus
Flavivirus
|
Infection
|
Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
|
-
- HY-P5373
-
|
Peptides
|
Others
|
Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed
the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the
Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N7123
-
Sulphacetamide
|
Infection
Classification of Application Fields
Disease Research Fields
|
Antibiotic
Bacterial
Fungal
|
Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections .
|
-
-
- HY-W145693
-
-
-
- HY-N2982
-
-
-
- HY-N10800
-
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione
|
Structural Classification
Terpenoids
Labiatae
Source classification
Samanea saman (Jacq.) Merr.
Diterpenoids
Plants
|
Others
|
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione is a kind of chemical constituents of Salvia miltiorrhiza f. alba. The dihydroisotanshinone with a para-quinone moiety shows cytotoxicity and anti-tumor activity .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-Y1630S
-
|
NSC 10281-d4 is the deuterium labeled NSC 10281 .
|
-
-
- HY-B0512S
-
|
Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine, a sulfonamide antibacterial, inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes .
|
-
-
- HY-76547S1
-
|
p-Toluic acid-d7 is the deuterium labeled p-Toluic acid . p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
|
-
-
- HY-W750432
-
|
Para red-d6 is a deuterated labeled Para red.
|
-
-
- HY-W588258S1
-
|
Para-topolin-d4 is deuterium labeled Para-topolin .
|
-
-
- HY-W739835
-
|
Para Red-d4 is the deuterium labeled Para Red .
|
-
-
- HY-76547S2
-
|
p-Toluic acid-d3 is the deuterium labeled p-Toluic acid . p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
|
-
-
- HY-76547S
-
|
p-Toluic acid-d4 is the deuterium labeled p-Toluic acid . p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
|
-
-
- HY-B0512S1
-
|
Sulfamerazine- 13C6 (RP2632- 13C6) is 13C labeled Sulfamerazine (HY-B0512). Sulfamerazine (RP-2632) is a sulfonamide antibacterial. Sulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes.
|
-
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