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Results for "

pH 6.0

" in MedChemExpress (MCE) Product Catalog:

By Targets:	17β-HSD (1) Aldose Reductase (1) Bacterial (1) Biochemical Assay Reagents (6) Complement System (1) Estrogen Receptor/ERR (1) Fluorescent Dye (3) Proton Pump (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Endocrinology (1) Inflammation/Immunology (3) Metabolic Disease (3) Neurological Disease (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Inhibitory Antibodies

Natural
Products

Targets Recommended: HIF/HIF Prolyl-Hydroxylase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1610L

Sodium Citrate Buffer, 0.5M, pH 6.0	Biochemical Assay Reagents	Others
Sodium citrate buffer, 0.5M, pH 6.0, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer, 0.5M, pH 6.0 is used for RNA isolation and antigens detection in fixed tissue .

HY-B2227B

Lactate (sodium) (60% in water) Maximum Cited Publications 26 Publications Verification Lactic acid sodium	Bacterial	Metabolic Disease Cancer
Lactate (60% in water) (Lactic acid) sodium is the product of glycogenolysis and glycolysis . Lactate sodium (60% in water) is an organic salt that is mainly used as a buffer and pH adjuster for injection solutions. Lactate sodium (60% in water) can be metabolized by the body into sodium bicarbonate, which in turn acts to increase the pH of the blood. Lactate sodium (60% in water) is used to improve metabolic acidosis and hypovolemic states. In terms of pharmaceutical preparations, Lactate sodium (60% in water) is often used in combination with sodium chloride, glucose, etc. to form normal saline or compound liquid intravenous injection . Lactate sodium (60% in water) also has antimicrobial activity, which can be used as a food preservative .

HY-101882

BCECF 1 Publications Verification 2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein	Fluorescent Dye	Others
BCECF is a *pH-sensitive* fluorescent dye. BCECF allows measurements in the physiological pH range 6.0–8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.

HY-W145108

Methyl red hydrochloride	Biochemical Assay Reagents	Others
Methyl red hydrochloride is an azo dye that acts as a pH indicator. Methyl red is red and yellow at pH 4.4 and 6.0 respectively .

HY-123184

S 1924	Proton Pump	Neurological Disease Metabolic Disease
S 1924 is a potent H+, K+-ATPase inhibitor, with IC₅₀ values of 10.3 and 1.6 μM at pH 7.4 and pH 6.0, respectively .

HY-Y0699R

Methyl red (Standard)	Fluorescent Dye	Others
Methyl red (Standard) is the analytical standard of Methyl red. This product is intended for research and analytical applications. Methyl red is an azo dye that acts as a pH indicator. Methyl red is red and yellow at pH 4.4 and 6.0 respectively .

HY-128545

Nitrazine yellow Nitrazine paper; pHenapHthazine	Biochemical Assay Reagents	Others
Nitrazine yellow (Nitrazine paper; Phenaphthazine) is a pH indicator. The color of Nitrazine yellow changes from yellow to blue in the pH range from 6.0 to 7.0. Nitrazine yellow is a kind of biological materials or organic compounds that are widely used in life science research .

HY-19153

Nepaprazole rel-TY-11345 free base	Proton Pump	Inflammation/Immunology
Nepaprazole (rel-TY-11345 free base) is a proton pump inhibitor. Nepaprazole inhibits H ⁺/K ⁺-ATPase activity in isolated rabbit gastric mucosal microsomes with the IC₅₀ values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively. Nepaprazole can be used for study of peptic ulcer diseases .

HY-D2324

EE-Flipper 33	Fluorescent Dye	Others
EE-Flipper 33 is a Flipper probe designed to evaluate the mechanism of early endocytosis. EE-Flipper has a pKa value of 10.6 and is capable of tracking approximately 70% of early endosomes (EE) in live cells. Furthermore, EE-Flipper 33 can also label the Golgi apparatus in live cells with an internal pH ranging from 6.0 to 6.7 .

HY-131586

3,7-Dihydroxyflavone Resogalangin	17β-HSD Estrogen Receptor/ERR Aldose Reductase	Endocrinology Cancer
3,7-Dihydroxyflavone (Resogalangin) is a flavonoid phytoestrogen, which can be isolated from Adenophora species. 3,7-Dihydroxyflavone is a modulator of estrogen receptors and an inhibitor of human progesterone metabolizing enzyme AKR1C1 and fungal 17β-hydroxysteroid dehydrogenase and a redox inhibitor (IC₅₀=0.6 and 6.0 μM, respectively). 3,7-Dihydroxyflavone is a fluorescent binding substrate for human serum albumin (HSA) with excitation wavelengths of 370 nm (pH 7.4) and 350 nm (pH 3.5), respectively, and emission wavelength of 515 nm .

HY-P99965

Crovalimab SKY59; RO7112689	Complement System	Cardiovascular Disease Metabolic Disease
Crovalimab (SKY59; RO7112689) is a novel humanized antibody against C5 in a pH-dependent manner with KDs of 15.2 nM and 16.8 μM at pH 7.4 and 5.8, respectively. Crovalimab binds human FcRn with great affinity (KD: 17 μM at pH 6.0). Crovalimab can block cleavage of C5 by the C5 convertase and inhibite the activity of a C5 variant (p.Arg885His). Crovalimab inhibits C5b-9 formation significantly in all three complement pathways, the classical pathway (CP), lectin pathway (LP), and alternative pathway (AP). Crovalimab has the potential for paroxysmal nocturnal hemoglobinuria (PNH) and complement-mediated diseases research .

HY-D0861

EGTA 15+ Cited Publications	Biochemical Assay Reagents	Inflammation/Immunology
EGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (K_d) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca ²⁺ over Mg ²⁺ (Mg ²⁺ K_d 1-10 mM). EGTA significantly inhibits the substrate adherence capacity of inflammatory macrophages .

HY-D0861A

EGTA tetrasodium	Biochemical Assay Reagents	Inflammation/Immunology
EGTA tetrasodium is a specific calcium ion chelator. EGTA tetrasodium has an apparent calcium dissociation constant (K_d) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca ²⁺ over Mg ²⁺ (Mg ²⁺ K_d 1-10 mM). EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages .

HY-E70569

α-N-acetylgalactosidase	Biochemical Assay Reagents	Others
α-N-acetylgalactosidase (EC 3.2.1.4) is a highly specific exoglycosidase that efficiently hydrolyzes α-N-acetylgalactosamine (GalNAc) linked to serine or threonine residues in glycoproteins (Tn antigen). α-N-acetylgalactosidase shows activity against α 1-3 linked terminal GalNAc . α-N-acetylgalactosidase is suitable for use in the pH range of 6.0-7.6 and does not require cofactors or special buffer systems.

Cat. No.	Product Name	Type

HY-101882

BCECF 1 Publications Verification 2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein	Fluorescent Dyes/Probes
BCECF is a *pH-sensitive* fluorescent dye. BCECF allows measurements in the physiological pH range 6.0–8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.

HY-D2324

EE-Flipper 33	Fluorescent Dyes/Probes
EE-Flipper 33 is a Flipper probe designed to evaluate the mechanism of early endocytosis. EE-Flipper has a pKa value of 10.6 and is capable of tracking approximately 70% of early endosomes (EE) in live cells. Furthermore, EE-Flipper 33 can also label the Golgi apparatus in live cells with an internal pH ranging from 6.0 to 6.7 .

Cat. No.	Product Name	Type

HY-B1610L

Sodium Citrate Buffer, 0.5M, pH 6.0	Buffer Reagents
Sodium citrate buffer, 0.5M, pH 6.0, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer, 0.5M, pH 6.0 is used for RNA isolation and antigens detection in fixed tissue .

HY-D0861

EGTA 15+ Cited Publications	Chelators
EGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (K_d) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca ²⁺ over Mg ²⁺ (Mg ²⁺ K_d 1-10 mM). EGTA significantly inhibits the substrate adherence capacity of inflammatory macrophages .

HY-W145108

Methyl red hydrochloride	Microbial Culture
Methyl red hydrochloride is an azo dye that acts as a pH indicator. Methyl red is red and yellow at pH 4.4 and 6.0 respectively .

HY-Y0699R

Methyl red (Standard)	Indicators
Methyl red (Standard) is the analytical standard of Methyl red. This product is intended for research and analytical applications. Methyl red is an azo dye that acts as a pH indicator. Methyl red is red and yellow at pH 4.4 and 6.0 respectively .

HY-128545

Nitrazine yellow Nitrazine paper; pHenapHthazine	Indicators
Nitrazine yellow (Nitrazine paper; Phenaphthazine) is a pH indicator. The color of Nitrazine yellow changes from yellow to blue in the pH range from 6.0 to 7.0. Nitrazine yellow is a kind of biological materials or organic compounds that are widely used in life science research .

HY-D0861A

EGTA tetrasodium	Biochemical Assay Reagents
EGTA tetrasodium is a specific calcium ion chelator. EGTA tetrasodium has an apparent calcium dissociation constant (K_d) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca ²⁺ over Mg ²⁺ (Mg ²⁺ K_d 1-10 mM). EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages .

Cat. No.	Product Name	Target	Research Area

HY-P99965

Crovalimab SKY59; RO7112689	Complement System	Cardiovascular Disease Metabolic Disease
Crovalimab (SKY59; RO7112689) is a novel humanized antibody against C5 in a pH-dependent manner with KDs of 15.2 nM and 16.8 μM at pH 7.4 and 5.8, respectively. Crovalimab binds human FcRn with great affinity (KD: 17 μM at pH 6.0). Crovalimab can block cleavage of C5 by the C5 convertase and inhibite the activity of a C5 variant (p.Arg885His). Crovalimab inhibits C5b-9 formation significantly in all three complement pathways, the classical pathway (CP), lectin pathway (LP), and alternative pathway (AP). Crovalimab has the potential for paroxysmal nocturnal hemoglobinuria (PNH) and complement-mediated diseases research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-131586

3,7-Dihydroxyflavone Resogalangin	Structural Classification Flavonoids Flavones Source classification Plants Fabaceae Zuccagnia punctata Cav.	17β-HSD Estrogen Receptor/ERR Aldose Reductase
3,7-Dihydroxyflavone (Resogalangin) is a flavonoid phytoestrogen, which can be isolated from Adenophora species. 3,7-Dihydroxyflavone is a modulator of estrogen receptors and an inhibitor of human progesterone metabolizing enzyme AKR1C1 and fungal 17β-hydroxysteroid dehydrogenase and a redox inhibitor (IC₅₀=0.6 and 6.0 μM, respectively). 3,7-Dihydroxyflavone is a fluorescent binding substrate for human serum albumin (HSA) with excitation wavelengths of 370 nm (pH 7.4) and 350 nm (pH 3.5), respectively, and emission wavelength of 515 nm .

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pH 6.0

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Inhibitory Antibodies

NaturalProducts

Natural
Products