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Results for "

p53 Activator 15

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MDM-2/p53 (1)
By Research Areas:	Cancer (1)

Targets Recommended: 15-PGDH Enteropeptidase EHD Protein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-175318S

**p53 Activator 15**	MDM-2/p53	Cancer
p53 Activator 15 (Compound 2) is an orally active *p53* activator. p53 Activator 15 enhances the bind ability of p53 Y220C to DNA and significantly suppresses cancer cells proliferation (IC₅₀: 58  nM for NUGC-3 cells), without inhibitory activity against CYP enzyme. p53 Activator 15 potently inhibits tumor growth in NUGC-3 xenograft mice model. p53 Activator 15 has a broad-spectrum anti-cancer activity, such as breast, stomach and lung cancer .

Cat. No.	Product Name	Chemical Structure

HY-175318S

**p53 Activator 15**
p53 Activator 15 (Compound 2) is an orally active *p53* activator. p53 Activator 15 enhances the bind ability of p53 Y220C to DNA and significantly suppresses cancer cells proliferation (IC₅₀: 58  nM for NUGC-3 cells), without inhibitory activity against CYP enzyme. p53 Activator 15 potently inhibits tumor growth in NUGC-3 xenograft mice model. p53 Activator 15 has a broad-spectrum anti-cancer activity, such as breast, stomach and lung cancer .

p53 Activator 15

p53 Activator 15 (Compound 2) is an orally active p53 activator. p53 Activator 15 enhances the bind ability of p53 Y220C to DNA and significantly suppresses cancer cells proliferation (IC₅₀: 58  nM for NUGC-3 cells), without inhibitory activity against CYP enzyme. p53 Activator 15 potently inhibits tumor growth in NUGC-3 xenograft mice model. p53 Activator 15 has a broad-spectrum anti-cancer activity, such as breast, stomach and lung cancer .

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p53 Activator 15

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