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Results for "

oxygen metabolism

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Mitochondrial Metabolism (1) Reactive Oxygen Species (ROS) (15) Androgen Receptor (1) Apoptosis (4) Biochemical Assay Reagents (1) Calcium Channel (1) Caspase (1) Cytochrome P450 (1) Endogenous Metabolite (7) Fatty Acid Synthase (FASN) (2) Ferroptosis (1) Fungal (2) GLUT (1) Glutaminase (1) HIF/HIF Prolyl-Hydroxylase (1) Interleukin Related (2) Isotope-Labeled Compounds (2) LXR (2) MMP (1) Monoamine Oxidase (1) NKCC (1) NOD-like Receptor (NLR) (2) Oxidative Phosphorylation (3) p38 MAPK (1) PDHK (1) PDK-1 (1) Photosensitizer (1) Reference Standards (3) Succinate Dehydrogenase (1)
By Research Areas:	Cancer (11) Cardiovascular Disease (2) Infection (2) Inflammation/Immunology (3) Metabolic Disease (8) Neurological Disease (1)

By Targets:

Mitochondrial Metabolism (1)

Reactive Oxygen Species (ROS) (15)

Androgen Receptor (1)

Apoptosis (4)

Biochemical Assay Reagents (1)

Calcium Channel (1)

Caspase (1)

Cytochrome P450 (1)

Endogenous Metabolite (7)

Fatty Acid Synthase (FASN) (2)

Ferroptosis (1)

Fungal (2)

GLUT (1)

Glutaminase (1)

HIF/HIF Prolyl-Hydroxylase (1)

Interleukin Related (2)

Isotope-Labeled Compounds (2)

LXR (2)

MMP (1)

Monoamine Oxidase (1)

NKCC (1)

NOD-like Receptor (NLR) (2)

Oxidative Phosphorylation (3)

p38 MAPK (1)

PDHK (1)

PDK-1 (1)

Photosensitizer (1)

Reference Standards (3)

Succinate Dehydrogenase (1)

By Research Areas:

Cancer (11)

Cardiovascular Disease (2)

Infection (2)

Inflammation/Immunology (3)

Metabolic Disease (8)

Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Mitochondrial Metabolism Reactive Oxygen Species (ROS)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-135849

Catalase, Aspergillus niger 3 Publications Verification	Reactive Oxygen Species (ROS)	Cancer
Catalase, Aspergillus niger is a key enzyme in the metabolism of H₂O₂ and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors . Free oxygen radical scavenger.

HY-153016

HIF-2α agonist 2	HIF/HIF Prolyl-Hydroxylase	Inflammation/Immunology
HIF-2α agonist 2 (compound 10) is a HIF-2α agonist with an EC₅₀ value of 1.68 μM at the dose of 20 μM. HIF-2α agonist 2 is non-cytotoxic against 786-O-HRE-Luc cells. HIF-2α agonist 2 can be used for oxygen metabolism research .

HY-P2888

Bilirubin oxidase BOD	Endogenous Metabolite	Metabolic Disease
Bilirubin oxidase (BOD) is a multi-copper oxidase that catalyzes the oxidation of bilirubin to biliverdin and reduces molecular oxygen to water. Bilirubin oxidase can participate in the metabolism of porphyrin and chlorophyll, and is widely used in biochemical research as a catalyst for oxygen reduction .

HY-113224

Desmosterol 5 Publications Verification	Endogenous Metabolite LXR Fatty Acid Synthase (FASN) Interleukin Related Reactive Oxygen Species (ROS) NOD-like Receptor (NLR)	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism . Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species (ROS) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases .

HY-B0831

Buprofezin 1 Publications Verification	Oxidative Phosphorylation Reactive Oxygen Species (ROS)	Others
Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .

HY-W770183

Uric acid-13C3	Isotope-Labeled Compounds	Others
Uric acid- ¹³C₃ is ¹³C-labeled Uric acid (HY-B2130). Uric acid is the end product of purine metabolism in the human body. Uric acid can scavenge reactive oxygen species (ROS), such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation.

HY-P2888B

Bilirubin oxidase, Magnaporthe oryzae BOD, Magnaporthe oryzae	Endogenous Metabolite	Metabolic Disease
Bilirubin oxidase (BOD), Magnaporthe oryza is a multi-copper oxidase that catalyzes the oxidation of bilirubin to biliverdin and reduces molecular oxygen to water. Bilirubin oxidase, Magnaporthe oryzae can participate in the metabolism of porphyrin and chlorophyll, and is widely used in biochemical research as a catalyst for oxygen reduction .

HY-149602

Glutaminase C-IN-2	Glutaminase Reactive Oxygen Species (ROS)	Cancer
Glutaminase C-IN-2 (compound 11) is glutaminase C (GAC) allosteric inhibitor with an IC₅₀ of 10.64 nM. Glutaminase C-IN-2 regulates the cellular metabolite, thereby increasing *reactive oxygen* species (ROS)** by blocking glutamine metabolism. Glutaminase C-IN-2 has anticancer effects .

HY-B0831S

Buprofezin-d6	Oxidative Phosphorylation Reactive Oxygen Species (ROS)	Metabolic Disease
Buprofezin-d₆ is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .

HY-113224R

Desmosterol (Standard)	Reference Standards Endogenous Metabolite LXR Fatty Acid Synthase (FASN) Interleukin Related Reactive Oxygen Species (ROS) NOD-like Receptor (NLR)	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Desmosterol (Standard) is the analytical standard of Desmosterol. This product is intended for research and analytical applications. Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species (ROS) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1][2][3].

HY-161027

DHP-B	Apoptosis	Cancer
DHP-B possesses anti-cancer activity and induces apoptosis. DHP-B covalently binds to Cys96 of CPT1A, blocks FAO, and disrupts the mitochondrial CPT1A-VDAC1 interaction, leading to increased mitochondrial permeability and reduced oxygen consumption and energy metabolism in CRC cells. DHP-B can be isolated from the plant Peperomia dindygulensis .

HY-B0831R

Buprofezin (Standard)	Oxidative Phosphorylation Reference Standards Reactive Oxygen Species (ROS)	Others
Buprofezin (Standard) is the analytical standard of Buprofezin. This product is intended for research and analytical applications. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .

HY-122723

GOT1 inhibitor-1 2 Publications Verification	Reactive Oxygen Species (ROS)	Cancer
GOT1 inhibitor-1 (compound 2c), a tryptamine-based derivative, acts as a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC₅₀ of 8.2 uM. GOT1 plays an important role in energy metabolism and Reactive Oxygen Species (ROS) balance. GOT1 inhibitor-1 can be used for the research of pancreatic ductal adenocarcinoma (PDAC) .

HY-158189

TPP-Ce6	Biochemical Assay Reagents Apoptosis Reactive Oxygen Species (ROS)	Others Cancer
Tpp-ce6 is a mitochondria-targeting photosensitizer formed by binding chlorophyll e6 (Ce6) to triphenylphosphine (TPP) via an ester bond. TPP-Ce6 can produce ROS under light irradiation, especially singlet oxygen, which can induce oxidative stress, leading to mitochondrial dysfunction and apoptosis. TPP-Ce6 can be used in the study of mitochondria in apoptosis and energy metabolism as well as cancer therapy .

HY-Y0445A

Sodium dichloroacetate Maximum Cited Publications 21 Publications Verification	PDK-1 NKCC PDHK Reactive Oxygen Species (ROS) Apoptosis	Cancer
Sodium dichloroacetate is an orally active pyruvate dehydrogenase kinase (PDK) inhibitor. Sodium dichloroacetate also stimulates pyruvate dehydrogenase (PDH) activity and works as a Na ⁺-K ⁺-2Cl ⁻ cotransporter (NKCC) inhibitor. Sodium dichloroacetate prevents the phosphorylation of the E1α subunit of PDC, promoting the entry of pyruvate into the mitochondria for oxidative metabolism, reducing lactate production, and simultaneously increasing the production of reactive oxygen species (ROS). Sodium dichloroacetate inhibits tumor cell proliferation and induces apoptosis. Sodium dichloroacetate is promising for research of cancers .

HY-108894

Ferumoxytol	Reactive Oxygen Species (ROS) Ferroptosis	Cancer
Ferumoxytol is an iron oxide nanoparticle. Ferumoxytol has anti-leukemic activity, especially against acute myeloid leukemia (AML) cells with low iron transporter protein (FPN) expression. Ferumoxytol increases intracellular iron content, triggers the Fenton reaction, generates reactive oxygen species (ROS), leads to oxidative stress and ferroptosis. Ferumoxytol can selectively kill leukemic cells with low FPN expression while avoiding toxicity to normal cells. Ferumoxytol can be used to study leukemias with targeted iron metabolism abnormalities .

HY-16731

Sembragiline EVT 302; RG1577; RO4602522	Monoamine Oxidase Reactive Oxygen Species (ROS)	Neurological Disease
Sembragiline (EVT 302) is a potent, selective and reversible monoamine oxidase B (MAO-B) inhibitor. Sembragiline reduces the metabolism of dopamine and other amine neurotransmitters by inhibiting the activity of the MAO-B enzyme, thereby potentially increasing the concentration of these neurotransmitters in the brain. Inhibition of the MAO-B enzyme also reduces the formation of toxic reactive oxygen species (ROS) that play a role in the pathological process of AD. Sembragiline has good oral activity and blood-brain barrier permeability. Sembragiline can be used in studies of AD, especially in patients with AD who show increased MAO-B activity .

HY-172777

SDH-IN-25	Succinate Dehydrogenase Fungal Reactive Oxygen Species (ROS) MMP	Infection
SDH-IN-25 is a succinate dehydrogenase (SDH) inhibitor (IC₅₀ = 4.82 mg/L). SDH-IN-25 exhibited broad-spectrum and potent antifungal activity. SDH-IN-25 mimics the interaction pattern of commercial fungicide Fluxapyroxad (HY-135549) through binding to SDH amino acid residues (TRP173, TYR58, and ARG43). SDH-IN-25 can induce hyphal morphology, interfere with respiratory metabolism by binding to complex II, generate *reactive oxygen* species (ROS), and affect mitochondrial membrane potential (MMP)** in mycelia. SDH-IN-25 can be studied in research for agricultural disease control .

HY-W012382

N-Acetyl-L-tyrosine	Endogenous Metabolite	Metabolic Disease Cancer
N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level *reactive oxygen* species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1** pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .

HY-174377

PeS-9	Androgen Receptor p38 MAPK Caspase Cytochrome P450 Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Mitochondrial Metabolism GLUT	Cancer
PeS-9 is an Androgen Receptor (AR) degrader that induces androgen receptor degradation PeS-9 induces mitochondrial and ER stress by promoting cytotoxic ROS production, leading to the release of mitochondrial cytochrome C and AIF. PeS-9 subsequently activates caspases-9 and -3, causing DNA fragmentation and apoptotic cell death. PeS-9 has anticancer activity against prostate cancer and exerts in vivo antitumor and antimetastatic activity with minor side effects. PeS-9 can be used for the study of targeting monotherapy against GLUT-1-overexpressing tumors .

HY-168066

Antifungal agent 117	Fungal	Infection
Antifungal agent 117 is a bis-pyrazole carboxamide derivative with antifungal activity, exhibiting an EC₅₀ value of 11.58 mg/L against Sclerotinia sclerotiorum. Antifungal agent 117 increases cell membrane permeability, causing an imbalance in osmotic pressure inside and outside the cell, and induces the accumulation of reactive oxygen species (ROS), leading to oxidative damage to the cell membrane, resulting in leakage of cellular contents and eventually cell death. RNA sequencing analysis reveals that Antifungal agent 117 downregulates catalase genes and upregulates neutral ceramidase genes, disrupting cell membrane structure, accelerating sphingolipid metabolism, and promoting cell death. Antifungal agent 117 shows great potential in the fields of plant protection and antifungal infection .

HY-W012382R

N-Acetyl-L-tyrosine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease Cancer
N-Acetyl-L-tyrosine (Standard) is the analytical standard of N-Acetyl-L-tyrosine (HY-W012382). This product is intended for research and analytical applications. N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level *reactive oxygen* species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1** pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .

HY-W012382S

N-Acetyl-L-tyrosine-d3	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease Cancer
N-Acetyl-L-tyrosine-d₃ is the deuterated form of N-Acetyl-L-tyrosine (HY-W012382). N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level *reactive oxygen* species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1** pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .

HY-W051271

Titanium(IV) oxide Titanium dioxide	Photosensitizer Reactive Oxygen Species (ROS)	Others
Titanium(IV) oxide is a photosensitizer and photocatalyst. Titanium(IV) oxide can be used as a pharmaceutical excipient such as a flow aid, coating agent, sunscreen, colorant, etc. Pharmaceutical excipients or pharmaceutical excipients refer to other chemical substances used in the pharmaceutical process other than the drug ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations that can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism and elimination (ADME) process of co-administered drugs. Titanium(IV) oxide can use light energy to generate electron-hole pairs to degrade pollutants. Photons excite electrons in TiO₂ to generate active oxygen species (such as ·OH and ·O₂ ^-), thereby oxidizing and mineralizing pollutants such as organic compounds and heavy metals. TiO₂ can be used in the research of environmental remediation fields such as water treatment, air purification and self-cleaning materials .

Cat. No.	Product Name

HY-L089

Mitochondria-Targeted Compound Library	860 compounds
Mitochondria plays an important role in many vital processes in cells, including energy production, fatty-acid oxidation and the Tricarboxylic Acid (TCA) cycle, calcium signaling, permeability transition, apoptosis and heat production. At present, it is recognized that many diseases are associated with impaired mitochondrial function, such as increased accumulation of ROS and decreased OXPHOS and ATP production. Mitochondria are recognized as one of the most important targets for new drug design in cancer, cardiovascular, and neurological diseases, etc. Some small molecule drugs or biologics can act on mitochondria through various pathways, including ETC inhibition, OXPHOS uncoupling, mitochondrial Ca²⁺ modulation, and control of oxidative stress via decrease or increase of mitochondrial ROS accumulation. MCE supplies a unique collection of 860 mitochondria-targeted compound that mainly targeting Mitochondrial Metabolism, ATP Synthase, Mitophagy, Reactive Oxygen Species, etc. MCE Mitochondria-Targeted Compound Library is a useful tool for mitochondria-targeted drug discovery and related research.

Mitochondria-Targeted Compound Library

860 compounds

Mitochondria plays an important role in many vital processes in cells, including energy production, fatty-acid oxidation and the Tricarboxylic Acid (TCA) cycle, calcium signaling, permeability transition, apoptosis and heat production. At present, it is recognized that many diseases are associated with impaired mitochondrial function, such as increased accumulation of ROS and decreased OXPHOS and ATP production. Mitochondria are recognized as one of the most important targets for new drug design in cancer, cardiovascular, and neurological diseases, etc. Some small molecule drugs or biologics can act on mitochondria through various pathways, including ETC inhibition, OXPHOS uncoupling, mitochondrial Ca²⁺ modulation, and control of oxidative stress via decrease or increase of mitochondrial ROS accumulation.

MCE supplies a unique collection of 860 mitochondria-targeted compound that mainly targeting Mitochondrial Metabolism, ATP Synthase, Mitophagy, Reactive Oxygen Species, etc. MCE Mitochondria-Targeted Compound Library is a useful tool for mitochondria-targeted drug discovery and related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113224

Desmosterol 5 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Source classification Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite LXR Fatty Acid Synthase (FASN) Interleukin Related Reactive Oxygen Species (ROS) NOD-like Receptor (NLR)
Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism . Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species (ROS) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases .

HY-W012382

N-Acetyl-L-tyrosine	Structural Classification Classification of Application Fields Source classification Endocrine diseases Metabolic Disease Endogenous metabolite Human Gut Microbiota Metabolites Monophenols Microorganisms Ketones, Aldehydes, Acids Disease markers Phenols Disease Research Fields	Endogenous Metabolite
N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level *reactive oxygen* species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1** pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .

HY-W012382R

N-Acetyl-L-tyrosine (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Phenols Endocrine diseases Endogenous metabolite	Reference Standards Endogenous Metabolite
N-Acetyl-L-tyrosine (Standard) is the analytical standard of N-Acetyl-L-tyrosine (HY-W012382). This product is intended for research and analytical applications. N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level *reactive oxygen* species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1** pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .

HY-113224R

Desmosterol (Standard)	Structural Classification Microorganisms Source classification Disease markers Endocrine diseases Endogenous metabolite Steroids	Reference Standards Endogenous Metabolite LXR Fatty Acid Synthase (FASN) Interleukin Related Reactive Oxygen Species (ROS) NOD-like Receptor (NLR)
Desmosterol (Standard) is the analytical standard of Desmosterol. This product is intended for research and analytical applications. Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species (ROS) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1][2][3].

Cat. No.	Product Name	Chemical Structure

HY-W012382S

N-Acetyl-L-tyrosine-d3
N-Acetyl-L-tyrosine-d₃ is the deuterated form of N-Acetyl-L-tyrosine (HY-W012382). N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level *reactive oxygen* species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1** pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .

N-Acetyl-L-tyrosine-d3

N-Acetyl-L-tyrosine-d₃ is the deuterated form of N-Acetyl-L-tyrosine (HY-W012382). N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .

HY-W770183

Uric acid-13C3
Uric acid- ¹³C₃ is ¹³C-labeled Uric acid (HY-B2130). Uric acid is the end product of purine metabolism in the human body. Uric acid can scavenge reactive oxygen species (ROS), such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation.

HY-B0831S

Buprofezin-d6
Buprofezin-d₆ is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .

Buprofezin-d6

Buprofezin-d₆ is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .

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