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Results for "

organochlorine

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119725
    Tetradifon

    		Insecticide Infection
    Tetradifon is a broad-spectrum organochlorine insecticide and an inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), which can be used to control a variety of mites. Tetradifon inhibits energy-related activities such as ADP-stimulated respiration, DNP and Mg 2+-stimulated ATPase, with an IC50 of 4.5-27 nmoL/mg mitochondrial protein. Tetradifon exerts oligomycin-like activity by inhibiting the oxidative phosphorylation process, inducing oxidative stress and interfering with bone metabolism. Tetradifon is currently mainly used in the research of mitochondrial function regulation, bone remodeling mechanism and nephrotoxicity of environmental pollutants .
    Tetradifon
  • HY-B1873
    Methoxychlor

    		Apoptosis Infection
    Methoxychlor is an organochlorine pesticide agent. Methoxychlor induces Ca 2 rise and apoptosis in HA59T cells .
    Methoxychlor
  • HY-116992
    Chloroneb

    Demosan; TERSAN SP(R)

    		 Bacterial Infection
    Chloroneb (Demosan) is a pesticide with fungicidal and plant-protective activities. Chloroneb can be used to detect organochlorine pesticide residues, showing good selectivity, stability and reproducibility. Chloroneb has been applied to the detection of licorice, cucumber, river water and soil samples with satisfactory results .
    Chloroneb
  • HY-119725R
    Tetradifon (Standard)

    		Reference Standards Insecticide Infection
    Tetradifon (Standard) is the analytical standard of Tetradifon (HY-119725). This product is intended for research and analytical applications. Tetradifon is a broad-spectrum organochlorine insecticide and an inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), which can be used to control a variety of mites. Tetradifon inhibits energy-related activities such as ADP-stimulated respiration, DNP and Mg 2+-stimulated ATPase, with an IC50 of 4.5-27 nmoL/mg mitochondrial protein. Tetradifon exerts oligomycin-like activity by inhibiting the oxidative phosphorylation process, inducing oxidative stress and interfering with bone metabolism. Tetradifon is currently mainly used in the research of mitochondrial function regulation, bone remodeling mechanism and nephrotoxicity of environmental pollutants .
    Tetradifon (Standard)
  • HY-114525
    Chlorbenside

    		Insecticide Others
    Chlorbenside is an organochlorine pesticide. Chlorbenside targets organism such as mites and ticks and possesses efficient ovicidal and larvicidal activities .
    Chlorbenside
  • HY-114525R
    Chlorbenside (Standard)

    		Insecticide Others
    Chlorbenside (Standard) is the analytical standard of Chlorbenside. This product is intended for research and analytical applications. Chlorbenside is an organochlorine pesticide. Chlorbenside targets organism such as mites and ticks and possesses efficient ovicidal and larvicidal activities .
    Chlorbenside (Standard)
  • HY-116016R
    Etilevodopa (Standard)

    		Dopamine Receptor Drug Metabolite Neurological Disease
    Chlorbenside (Standard) is the analytical standard of Chlorbenside. This product is intended for research and analytical applications. Chlorbenside is an organochlorine pesticide. Chlorbenside targets organism such as mites and ticks and possesses efficient ovicidal and larvicidal activities .
    Etilevodopa (Standard)
  • HY-117179
    Endosulfan sulfate

    		Parasite Infection
    Endosulfan sulfate is the major metabolite of the insecticide Endosulfan, used for various crops. Endosulfan sulfate is more toxic and persistent than Endosulfan .
    Endosulfan sulfate
  • HY-117179R
    Endosulfan sulfate (Standard)

    		Reference Standards Parasite Infection
    Endosulfan sulfate (Standard) is the analytical standard of Endosulfan sulfate. This product is intended for research and analytical applications. Endosulfan sulfate is the major metabolite of the insecticide Endosulfan, used for various crops. Endosulfan sulfate is more toxic and persistent than Endosulfan .
    Endosulfan sulfate (Standard)
  • HY-116992R
    Chloroneb (Standard)

    		Bacterial Infection
    Chloroneb (Standard) is the analytical standard of Chloroneb. This product is intended for research and analytical applications. Chloroneb (Demosan) is a pesticide with fungicidal and plant-protective activities. Chloroneb can be used to detect organochlorine pesticide residues, showing good selectivity, stability and reproducibility. Chloroneb has been applied to the detection of licorice, cucumber, river water and soil samples with satisfactory results .
    Chloroneb (Standard)
  • HY-B1984
    p,p'-DDD

    4,4'-DDD; p,p'-Dichlorodiphenyl dichloroethane

    		 Drug Metabolite Apoptosis Necroptosis Insecticide Infection Neurological Disease Cancer
    p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats .
    p,p'-DDD
  • HY-B1984S
    p,p'-DDD-d8

    4,4'-DDD-d8; p,p'-Dichlorodiphenyl dichloroethane-d8

    		 Drug Metabolite Apoptosis Necroptosis Insecticide Infection Neurological Disease Cancer
    p,p'-DDD-d8 is the deuterium labeled p,p'-DDD[1]. p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats .
    p,p'-DDD-d8
  • HY-B1984R
    p,p'-DDD (Standard)

    4,4'-DDD (Standard); p,p'-Dichlorodiphenyl dichloroethane (Standard)

    		 Drug Metabolite Apoptosis Necroptosis Insecticide Infection Neurological Disease Cancer
    p,p'-DDD (Standard) is the analytical standard of p,p'-DDD (HY-B1984) . This product is intended for research and analytical applications. p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats.
    p,p'-DDD (Standard)
  • HY-121779
    o,p'-DDE

    2,4'-DDE; 2,4-Dichlorodiphenyldichloroethylene; 2,4'-DDE; o,p'-Dichlorodiphenyldichloroethylene

    		 Insecticide Endocrinology
    o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass, and in sediments from DDT manufacturing plants around the Huntsville Spring Branch-Indian Creek tributary system, where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to the rainbow trout estrogen receptor (rtER) with an IC50 value of 3.2 μM. It induces concentration-dependent estradiol secretion in co-cultures of granulosa and theca cells isolated from porcine follicles. In ovo exposure to o,p'-DDE increases follicular degeneration and reduces testis size in Japanese medaka (O. latipes).
    o,p'-DDE

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