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Results for "

non-immunogenicity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Biochemical Assay Reagents (2) Drug Derivative (1) IFNAR (1) NO Synthase (1) TNF Receptor (1)
By Research Areas:	Infection (1) Inflammation/Immunology (2)
Oligonucleotides:	Aptamers (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Oligonucleotides

Targets Recommended: TNK1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107634

CP-20961 Avridine	IFNAR	Infection Inflammation/Immunology
CP-20961 is an interferon inducer. CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis .

HY-160429

PSAR18-COOH	Drug Derivative	Others
PSAR18-COOH is a derivative of PSAR extracted from patent WO2009064913A1. PSAR is a highly hydrophilic, biodegradable, non-immunogenic and water-soluble polymer that has been employed in several delivery systems for drugs or diagnostics.

HY-158222

Alginate Methacryloyl (MW 50000) AlgMA (MW 50000)	Biochemical Assay Reagents	Others
Alginate Methacryloyl (MW 50000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 50000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 50000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-158222A

Alginate Methacryloyl (MW 300000) AlgMA (MW 300000)	Biochemical Assay Reagents	Others
Alginate Methacryloyl (MW 300000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 300000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 300000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-177406

VR11 aptamer	TNF Receptor Apoptosis NO Synthase	Inflammation/Immunology
VR11 aptamer is a DNA-based TNF-α inhibitor with a K_D of 7.0 nM. VR11 aptamer prevents TNFα-induced apoptosis and NO production. VR11 aptamer has non-immunogenicity and does not raise immune responses when injected intraperitoneally into C57BL/6 mice model. VR11 aptamer can be used for inflammatory diseases research .

Cat. No.	Product Name

HY-L038

Differentiation Inducing Compound Library	2,039 compounds
Stem cells, which are found in all multi-cellular organisms, can divide and differentiate into diverse special cell types and can self-renew to produce more stem cells. To be useful in therapy, stem cells must be converted into desired cell types as necessary which is called induced differentiation or directed differentiation. Understanding and using signaling pathways for differentiation is an important method in successful regenerative medicine. Small molecules or growth factors induce the conversion of stem cells into appropriate progenitor cells, which will later give rise to the desired cell type. There is a variety of signal molecules and molecular families that may affect the establishment of germ layers in vivo, such as fibroblast growth factors (FGFs); the wnt family or superfamily of transforming growth factors β (TGFβ) and bone morphogenetic proteins (BMP). Unfortunately, for now, a high cost of recombinant factors is likely to limit their use on a larger scale in medicine. The more promising technique focuses on the use of small molecules. These small molecules can be used for either activating or deactivating specific signaling pathways. They enhance reprogramming efficiency by creating cells that are compatible with the desired type of tissue. It is a cheaper and non-immunogenic method. MCE Differentiation Inducing Compound Library contains a unique collection of 2,039 compounds that act on signaling pathways for differentiation. These compounds are potential stimulators for induced differentiation. This library is a useful tool for researching directed differentiation and regenerative medicine.

Differentiation Inducing Compound Library

2,039 compounds

Stem cells, which are found in all multi-cellular organisms, can divide and differentiate into diverse special cell types and can self-renew to produce more stem cells. To be useful in therapy, stem cells must be converted into desired cell types as necessary which is called induced differentiation or directed differentiation. Understanding and using signaling pathways for differentiation is an important method in successful regenerative medicine. Small molecules or growth factors induce the conversion of stem cells into appropriate progenitor cells, which will later give rise to the desired cell type. There is a variety of signal molecules and molecular families that may affect the establishment of germ layers in vivo, such as fibroblast growth factors (FGFs); the wnt family or superfamily of transforming growth factors β (TGFβ) and bone morphogenetic proteins (BMP). Unfortunately, for now, a high cost of recombinant factors is likely to limit their use on a larger scale in medicine. The more promising technique focuses on the use of small molecules. These small molecules can be used for either activating or deactivating specific signaling pathways. They enhance reprogramming efficiency by creating cells that are compatible with the desired type of tissue. It is a cheaper and non-immunogenic method.

MCE Differentiation Inducing Compound Library contains a unique collection of 2,039 compounds that act on signaling pathways for differentiation. These compounds are potential stimulators for induced differentiation. This library is a useful tool for researching directed differentiation and regenerative medicine.

Cat. No.	Product Name	Type

HY-158222

Alginate Methacryloyl (MW 50000) AlgMA (MW 50000)	3D Bioprinting
Alginate Methacryloyl (MW 50000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 50000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 50000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.

Alginate Methacryloyl (MW 50000)

AlgMA (MW 50000)

3D Bioprinting

Alginate Methacryloyl (MW 50000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 50000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 50000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-158222A

Alginate Methacryloyl (MW 300000) AlgMA (MW 300000)	3D Bioprinting
Alginate Methacryloyl (MW 300000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 300000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 300000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.

Alginate Methacryloyl (MW 300000)

AlgMA (MW 300000)

3D Bioprinting

Alginate Methacryloyl (MW 300000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 300000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 300000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.

Cat. No.	Product Name	Target	Research Area

HY-160429

PSAR18-COOH	Drug Derivative	Others
PSAR18-COOH is a derivative of PSAR extracted from patent WO2009064913A1. PSAR is a highly hydrophilic, biodegradable, non-immunogenic and water-soluble polymer that has been employed in several delivery systems for drugs or diagnostics.

Cat. No.	Product Name		Classification

HY-177406

VR11 aptamer		Aptamers
VR11 aptamer is a DNA-based TNF-α inhibitor with a K_D of 7.0 nM. VR11 aptamer prevents TNFα-induced apoptosis and NO production. VR11 aptamer has non-immunogenicity and does not raise immune responses when injected intraperitoneally into C57BL/6 mice model. VR11 aptamer can be used for inflammatory diseases research .

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