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non-fluorescent

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36

Inhibitors & Agonists

24

Fluorescent Dye

1

Biochemical Assay Reagents

5

Peptides

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2267
    LDV
    1 Publications Verification

    		 Integrin Others
    LDV is a non-fluorescent analog of LDV-FITC. LDV is a α4β1 integrin (VLA-4) ligand, and binds α4β1 integrin in leukemia cells .
    LDV
  • HY-145612
    Sudan red 7B

    		Biochemical Assay Reagents Others
    Sudan red 7B is a red non-fluorescent stain that can be used to stain fat bodies .
    Sudan red 7B
  • HY-D1707
    FDGlcU

    		Fluorescent Dye Others
    FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm) .
    FDGlcU
  • HY-D1699
    PFB-FDG

    		Fluorescent Dye Others
    PFB-FDG is a non-fluorescent galactosidase substrate that can be hydrolysed to green fluorescent PFB-F (Ex=485 nm, Em=535 nm). PFB-FDG can be used for the determination of β-galactosidase activity .
    PFB-FDG
  • HY-111474
    Para-aminoblebbistatin

    		Myosin Cardiovascular Disease Neurological Disease
    Para-aminoblebbistatin is the inhibitor for myosin II. Para-aminoblebbistatin inhibits the ATPase activity of myosin II, thereby blocking the formation and contraction of the actin-myosin network. Para-aminoblebbistatin is a non-fluorescent and photostable Blebbistatin (HY-13813) derivative .
    Para-aminoblebbistatin
  • HY-W011024
    (2R,3S)-N-Cbz-6-oxo-2,3-diphenylmorpholine

    		Biochemical Assay Reagents Others
    (2R,3S)-N-Cbz-6-oxo-2,3-diphenylmorpholine is a chiral building block, which can be used in the stereoselective synthesis of fluorescent and non-fluorescent amino acids .
    (2R,3S)-N-Cbz-6-oxo-2,3-diphenylmorpholine
  • HY-101894
    Dihydrorhodamine 123
    Maximum Cited Publications
    13 Publications Verification

    DHR 123

    		 Fluorescent Dye Others
    Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
    Dihydrorhodamine 123
  • HY-D1416
    HMBR

    		Fluorescent Dye Others
    HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525–539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability .
    HMBR
  • HY-P2120
    Pseudobactin A

    		Bacterial Others
    Pseudobactin A is a non-fluorescent extracellular iron carrier produced by the plant growth-promoting bacterium Pseudomonas B10 .
    Pseudobactin A
  • HY-145612S
    Sudan red 7B-d5

    		Isotope-Labeled Compounds Others
    Sudan Red 7B-d5 is a deuterated labeled Sudan red 7B . Sudan red 7B is a red non-fluorescent stain that can be used to stain fat bodies .
    Sudan red 7B-d5
  • HY-120972
    Pentafluorobenzenesulfonyl fluorescein

    		Fluorescent Dye Others
    Pentafluorobenzenesulfonyl fluorescein is a H2O2-selective sensor that can be used to detect H2O2 levels in cells. Pentafluorobenzenesulfonyl fluorescein is normally non-fluorescent but fluoresces upon perhydrolysis of the sulfonyl linkage by H2O2 .
    Pentafluorobenzenesulfonyl fluorescein
  • HY-D0715
    Fluorescamine

    Ro 20-7234

    		 Fluorescent Dye Others
    Fluorescamine is a spirocyclic compound that is non-fluorescent. Fluorescamine reacts rapidly with primary amine groups in proteins under alkaline conditions to generate products with strong fluorescence (Ex/Em: 390/475 nm). Fluorescamine can be used to detect amine-containing compounds, including amino acids, peptides, and proteins .
    Fluorescamine
  • HY-D1682
    NFQ1

    		Fluorescent Dye Others
    NFQ1 is a non-fluorescent quencher (absorption wavelength: 474 nm), and is used for a new type of One Sample Fluorescence Resonance Energy Transfer (OS-FRET) method. OS-FRET enable measurement of unquenched donor emission in the same sample. NFQ1 shows broad absorption spectrum ensuring its utility as a dark acceptor for many donors .
    NFQ1
  • HY-D1687
    Flubi-2

    		Fluorescent Dye Others
    Flubi-2 is a fluorescein-biotin based pH-ratio dye (Ex=480 nm, Em= 520-560 nm) with a pK value of 6.7. Flubi-2 is a hydrolysis product of Flubida-2 (non-fluorescent, membrane permeable). Flubi-2 can be used for pH determination of organelles of the secretory pathway (such as golgi apparatus and endoplasmic reticulum) in living cells .
    Flubi-2
  • HY-D0715R
    Fluorescamine (Standard)

    Ro 20-7234 (Standard)

    		 Fluorescent Dye Others
    Fluorescamine (Standard) is the analytical standard of Fluorescamine (HY-D0715). This product is intended for research and analytical applications. Fluorescamine is a spirocyclic compound that is non-fluorescent. Fluorescamine reacts rapidly with primary amine groups in proteins under alkaline conditions to generate products with strong fluorescence (Ex/Em : 390/475 nm). Fluorescamine can be used to detect amine-containing compounds, including amino acids, peptides, and proteins .
    Fluorescamine (Standard)
  • HY-111391
    Resazurin sodium
    3 Publications Verification

    Diazoresorcinol sodium

    		 Bacterial Fluorescent Dye Infection
    Resazurin sodium (Diazoresorcinol sodium) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
    Resazurin sodium
  • HY-D1462
    CellTracker Blue CMAC

    		Fluorescent Dye Others
    CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .
    CellTracker Blue CMAC
  • HY-118540
    Resazurin

    Diazoresorcinol

    		 Fluorescent Dye Bacterial Infection
    Resazurin (Diazoresorcinol) is a water-soluble, non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
    Resazurin
  • HY-111391A
    Resazurin sodium, indicator

    Diazoresorcinol sodium, indicator

    		 Bacterial Fluorescent Dye Others
    Resazurin (Diazoresorcinol) sodium, indicator is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium, indicator is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium, indicator can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
    Resazurin sodium, indicator
  • HY-D1755
    Fluo-3FF AM

    		Fluorescent Dye Others
    Fluo-3FF AM is a low affinity (Kd = 42 μM) fluorescent Ca 2+ sensitive indicator (Abs/Em = 462 nm/526 nm). Fluo-3FF AM is Mg 2+ insensitive and relatively photostable. Fluo-3FF AM is an analog of Fluo-3FF AM. Fluo-3FF AM is essentially non-fluorescent, but exhibits a strong fluorescence enhancement upon entry into cells and binding to calcium.
    Fluo-3FF AM
  • HY-D0042
    NBD-Cl
    1 Publications Verification

    NBD chloride

    		 Fluorescent Dye Others
    NBD-Cl is a nonfluorescent reagent which becomes highly fluorescent after reaction with thiol or amino groups .
    NBD-Cl
  • HY-153006
    2,7-Dichlorodihydrofluorescein
    5 Publications Verification

    DCFH2

    		 Biochemical Assay Reagents Others
    2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent reactive oxygen species (ROS) probe with an excitation wavelength of 485-500 nm and an emission wavelength of 515-530 nm. 2,7-Dichlorodihydrofluorescein is first hydrolyzed by intracellular esterases and then oxidized by ROS to generate non-biomembrane-permeable, highly fluorescent 2,7-dichlorofluorescein (DCF). The fluorescence intensity of DCF is positively correlated with the ROS concentration. 2,7-Dichlorodihydrofluorescein can undergo oxidation reactions with a variety of ROS (such as ·OH, H2O2, ONOO -, etc.) and is used to quantitatively detect the level of oxidative stress inside and outside cells. It is suitable for oxidative stress analysis in in vitro cell models and in vivo targeted delivery (such as liver-targeted liposomes) .
    2,7-Dichlorodihydrofluorescein
  • HY-100041
    Bromobimane
    5 Publications Verification

    Monobromobimane

    		 Fluorescent Dye Others
    Bromobimane (Monobromobimane) is a nonfluorescent and converts into fluorescent products when reacts with thiols. Bromobimane has potential applications in labeling thiols .
    Bromobimane
  • HY-133535
    PA Janelia Fluor® 646, SE

    PA-JF646-NHS

    		 Fluorescent Dye Others
    PA Janelia Fluor® 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag ® and SNAP-tag ®. PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λExcitation/emission~650/664 nm). Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    PA Janelia Fluor® 646, SE
  • HY-D1045A
    Dabcyl acid sodium

    DABCYL sodium; Para-methyl red sodium

    		 Fluorescent Dye Others
    Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
    Dabcyl acid sodium
  • HY-D1045
    Dabcyl acid

    DABCYL; Para-methyl red

    		 Fluorescent Dye Others
    Dabcyl acid (Dabcyl) is a nonfluorescent chromophore and a quencher. Dabcyl acid can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
    Dabcyl acid
  • HY-P2496
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled

    		Endothelin Receptor Cardiovascular Disease
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB .
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled
  • HY-D2379A
    closed-HMRG

    		Fluorescent Dye
    closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of Hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent .
    closed-HMRG
  • HY-110250
    DFHBI
    5+ Cited Publications

    		 Fluorescent Dye Others
    DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). DFHBI can be used for imaging RNA in living cells. . Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells (Ex/Em = 469/501 nm).
    DFHBI
  • HY-P2089
    Dnp-PYAYWMR

    		MMP Others
    Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm .
    Dnp-PYAYWMR
  • HY-112526
    Thiofluor 623

    		Fluorescent Dye Others
    Thiofluor 623 (Compound 3) is a fluorescent turn-on probe that can be used for the selective sensing and bioimaging of thiols. Thiofluor 623 displays excellent immunity to interference from nitrogen and oxygen nucleophiles. Thiofluor 623 is essentially nonfluorescent in the absence of thiols, which cleave the probe and release the red-emissive donor-acceptor fluorophore (Ex=563 nm, Em=623 nm) .
    Thiofluor 623
  • HY-P3106
    (Z-Ala-Ala-Ala-Ala)2Rh110

    (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-alanyl-L-arginine amide Rhodamine 110

    		 Fluorescent Dye Others
    (Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.
    (Z-Ala-Ala-Ala-Ala)2Rh110
  • HY-W247098
    Dihydrorhodamine 6G

    DHR 6G

    		 Reactive Oxygen Species Cancer
    Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide .
    Dihydrorhodamine 6G
  • HY-D2735
    QSY-9-succinimidyl ester

    		Fluorescent Dye Others
    QSY-9-succinimidyl ester is a nonfluorescent acceptor molecule with a terminal NHS ester group. QSY-9-succinimidyl ester has a wide and intense quenching range from 500-600 nm that makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with fluorescent dyes at 500 nm to 600 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    QSY-9-succinimidyl ester
  • HY-D1373
    HBC
    1 Publications Verification

    HBC 530

    		 Fluorescent Dye Others
    HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is nonfluorescent in solution, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm) .
    HBC
  • HY-133821
    N-Methylmesoporphyrin IX

    		G-quadruplex Neurological Disease
    N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies .
    N-Methylmesoporphyrin IX

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