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Results for "

nitrite

" in MedChemExpress (MCE) Product Catalog:

29

Inhibitors & Agonists

1

Fluorescent Dye

3

Biochemical Assay Reagents

6

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W034067
    Silver nitrite

    		Biochemical Assay Reagents Bacterial Infection
    Silver nitrite is an inorganic compound with the chemical formula AgNO2. Silver nitrite can inhibit cell division and bacterial growth by interfering with protein synthesis .
    Silver nitrite
  • HY-W004843
    3-Amino-1,2,4-triazine

    		NO Synthase Others
    3-Amino-1,2,4-triazine is an inhibitor of NO synthase, and also inhibits nitrite secretion .
    3-Amino-1,2,4-triazine
  • HY-131521
    Oxalomalic acid trisodium

    Oxalomalate trisodium

    		 Isocitrate Dehydrogenase (IDH) Cancer
    Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages .
    Oxalomalic acid trisodium
  • HY-Y1132
    2-Amino-6-chlorobenzoic acid

    6-Chloroanthranilic acid

    		 Biochemical Assay Reagents Others
    2-Amino-6-chlorobenzoic acid is an autocoupling diazotization reagent used for spectrophotometric detection of nitrite ions in water. 2-Amino-6-chlorobenzoic acid exhibits good tolerance to various anions under acidic conditions. 2-Amino-6-chlorobenzoic acid is commonly used as a reagent in organic synthesis and analytical chemistry .
    2-Amino-6-chlorobenzoic acid
  • HY-D0073
    2,3-Diaminonaphthalene

    		Fluorescent Dye Others
    2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium ion detection and also used for the fluorometric determination of nitrite.
    2,3-Diaminonaphthalene
  • HY-W579772
    Tetrabutylammonium (nitrite)

    		Bacterial Infection
    Tetrabutylammonium (nitrite) is a compound with antibacterial activity. Tetrabutylammonium (nitrite) has inhibitory activity against some Gram-negative bacteria and some Gram-positive bacteria .
    Tetrabutylammonium (nitrite)
  • HY-23206
    DAN-1 EE hydrochloride

    		Biochemical Assay Reagents Others
    DAN-1 EE hydrochloride is a fluorescent indicator, which can be used for the detection of nitrite content in vitro and biological process .
    DAN-1 EE hydrochloride
  • HY-W923770
    N-(1-Naphthyl)ethylenediamine dihydrochloride monomethanolate

    		Biochemical Assay Reagents Others
    N-(1-Naphthyl)ethylenediamine dihydrochloride monomethanolate is a reagent that can be used for the spectrophotometric determination of nitrite and nitrate .
    N-(1-Naphthyl)ethylenediamine dihydrochloride monomethanolate
  • HY-138896
    (9E,11E)-9-Nitro-9,11-octadecadienoic acid

    9E,11E-9-Nitro CLA

    		 Endogenous Metabolite Others
    (9E,11E)-9-Nitro-9,11-octadecadienoic acid (9E,11E-9-Nitro CLA) is a nitro-fatty acid, It is formed by exposure of 9Z, 11E-CLA to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite .
    (9E,11E)-9-Nitro-9,11-octadecadienoic acid
  • HY-163848
    Anti-inflammatory agent 90

    		Interleukin Related Inflammation/Immunology
    Anti-inflammatory agent 90 (compound (R)-7) demonstrates decreasing of 32 % and 40 % for nitrite and IL-6, respectively in LPS-challenged RAW cells .
    Anti-inflammatory agent 90
  • HY-W726392
    N-Nitrosometoprolol

    		Adrenergic Receptor Endocrinology
    N-Nitrosometoprolol is an N-nitroso derivative formed by the in vitro reaction of β-adrenergic blockers with sodium nitrite. N-Nitrosometoprolol can induce micronuclei in rat liver, bone marrow and spleen .
    N-Nitrosometoprolol
  • HY-W507009
    L-Arginyl-L-alanine

    		Endogenous Metabolite Cardiovascular Disease
    L-Arginyl-L-alanine is a dipeptide, is a vascular smooth muscle-derived relaxing factor. L-Arginyl-L-alanine increases the smooth muscle levels of cyclic GMP and nitrite in endothelium-denuded arterial rings .
    L-Arginyl-L-alanine
  • HY-N2556
    Tirucallol

    		Others Inflammation/Immunology
    Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages .
    Tirucallol
  • HY-P2996
    NAD(P)H-Nitrate reductase

    		Others Others
    NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .
    NAD(P)H-Nitrate reductase
  • HY-162093
    Aβ1–42 aggregation inhibitor 2

    		Amyloid-β Neurological Disease
    Aβ1–42 aggregation inhibitor 2 (compound 7c) is a potent inhibitor of Aβ1-42 aggregation that plays an important role in Alzheimer's disease research. Aβ1–42 aggregation inhibitor 2 displays excellent antioxidant, metal ions chelating, oxidative stress alleviation, neuroprotective and anti-neuroinflammatory activities .
    Aβ1–42 aggregation inhibitor 2
  • HY-138564
    NOS-IN-1

    		NO Synthase Inflammation/Immunology
    NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively .
    NOS-IN-1
  • HY-N8691
    2',6'-Dihydroxy-4'-methoxydihydrochalcone

    		Parasite Infection Inflammation/Immunology
    2',6'-Dihydroxy-4'-methoxydihydrochalcone is an orally active dihydrochalcone compound with antiplasmodial and anti-inflammatory activities. 2',6'-Dihydroxy-4'-methoxydihydrochalcone reduces the IL-1β, TNF, and nitrite levels in vitro .
    2',6'-Dihydroxy-4'-methoxydihydrochalcone
  • HY-N0577
    Apiin
    1 Publications Verification

    Apigenin 7-O-apiosylglucoside; Apigenin 7-(2-O-apiosylglucoside)

    		 NO Synthase Inflammation/Immunology
    Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells .
    Apiin
  • HY-P2996A
    Nitrate Reductase, Arabidopsis thaliana

    		Drug Isomer Others
    Nitrate Reductase, Arabidopsis thaliana is the isomer of NAD(P)H-Nitrate reductase (HY-P2996). NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants，the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .
    Nitrate Reductase, Arabidopsis thaliana
  • HY-172786
    Caspase-3-IN-3

    		Caspase Apoptosis Metabolic Disease
    Caspase-3-IN-3 (compound 7) is a caspase 3 inhibitor. Caspase-3-IN-3 increases cellular ATP levels, inhibits caspase-3 activity, decreases nitrite production, suppresses cytokine-induced apoptosis, and restores Glucose (HY-B0389)-stimulated insulin secretion .
    Caspase-3-IN-3
  • HY-W048682
    Fmoc-1-methyl-L-histidine

    		Amino Acid Derivatives Others
    Fmoc-1-methyl-L-histidine is a Fmoc protected amino acid and amino acid-containing building block. Fmoc-1-methyl-L-histidine can be used in the production of ε-nitrogen-ligated copper centers in copper nitrite reductases. Fmoc-1-methyl-L-histidine can also be used as an intermediate for peptide synthesis .
    Fmoc-1-methyl-L-histidine
  • HY-176779
    Guanidino ethyl disulfide

    		NO Synthase Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Guanidino ethyl disulfide (GED) (Compound 23) is a NO Synthase (NOS) inhibitor with EC50s of 110, 630 and 180  μM for iNOS, eNOS and bNOS, respectivly. Guanidino ethyl disulfide effectively inhibits nitrite production in J774.2 macrophages. Guanidino ethyl disulfide can be used for circulatory shock, inflammation and neurological diseases research .
    Guanidino ethyl disulfide
  • HY-N0577R
    Apiin (Standard)

    Apigenin 7-O-apiosylglucoside (Standard); Apigenin 7-(2-O-apiosylglucoside) (Standard)

    		 Reference Standards NO Synthase Inflammation/Immunology
    Apiin (Standard) is the analytical standard of Apiin. This product is intended for research and analytical applications. Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells .
    Apiin (Standard)
  • HY-148983
    Hydroxylamine

    		Monoamine Oxidase Cardiovascular Disease
    Hydroxylamine is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine is a intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .
    Hydroxylamine
  • HY-Y0882
    Hydroxylamine hydrochloride

    		Monoamine Oxidase Cardiovascular Disease
    Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .
    Hydroxylamine hydrochloride
  • HY-N10770
    5'-Geranyl-5,7,2',4'-tetrahydroxyflavone

    		Others Metabolic Disease
    5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .
    5'-Geranyl-5,7,2',4'-tetrahydroxyflavone
  • HY-Y0882S1
    Hydroxylamine-d3 hydrochloride

    		Monoamine Oxidase Cardiovascular Disease
    Hydroxylamine-d3 (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride. Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .
    Hydroxylamine-d3 hydrochloride
  • HY-162963
    PPARδ agonist 11

    		PPAR Inflammation/Immunology
    PPARδ agonist 11 (Compound 11) is a selective agonist for PPARδ with an EC50 of 20 nM. PPARδ agonist 11 reduces the levels of nitrite oxide (NO), proinflammatory cytokines TNFα and IL-6 in LPS (HY-D1056)-stimulated RAW264.7 cell, and exhibits anti-inflammatory efficacy via NF-κB pathway. PPARδ agonist 11 exhibits good stability in human liver microsomes and plasma. PPARδ agonist 11 ameliorates Carrageenan (HY-125474)-induced foot edema .
    PPARδ agonist 11
  • HY-177050
    RG-239

    		G protein-coupled Bile Acid Receptor 1 Metabolic Disease Inflammation/Immunology
    RG-239 is an orally active TGR5 agonist with an EC50 of 120 nM, significantly outperforming Betulinic acid (HY-10529) (EC50 = 1.04 μM). RG-239 demonstrates higher selectivity for TGR5 compared to the FXRα. RG-239 increases mitochondrial activity in adipocytes and promotes neurite outgrowth at higher concentrations. RG-239 inhibits LPS (HY-D1056)-induced iNOS expression and nitrite production in Raw264.7 and microglia cells. RG-239 can be used for the study of type 2 diabetes [1][2][3][4][5].
    RG-239

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