Search Result
Results for "
near-infrared
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W588722
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Fluorescent Dye
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Others
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ICG-DBCO is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 789/813 nm
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- HY-D2195
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Fluorescent Dye
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Others
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AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.
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- HY-D1041
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ICG NHS ester
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Fluorescent Dye
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Cancer
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ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .
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- HY-139579
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OTL 38
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Fluorescent Dye
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Cancer
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Pafolacianine (OTL 38) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine excites at 774 to 775 nm and emits at 794 to 796 nm .
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- HY-D2312
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Fluorescent Dye
Ferroptosis
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Cancer
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Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) .
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- HY-D1463
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- HY-152102
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Fluorescent Dye
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Cancer
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BTCy is a near-infrared (NIR) fluorescence probe with polarity-responsive and cell plasma membrane-targeting properties. BTCy can be used for in vivo imaging of tumor tissue (λex = 561 nm, λem = 600-700 nm) .
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- HY-D2280
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HDAC
Estrogen Receptor/ERR
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Others
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Estrogen receptor β/HDAC probe 1 (compound P1) is a near-infrared fluorescent probe that dual-targets the estrogen receptor (Estrogen Receptor/ERR) β/histone deacetylase HDAC .
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- HY-D1367
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Fluorescent Dye
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Sulfo-Cyanine7 carboxylic acid is a highly hydrophilic and water-soluble near-infrared dye. It improves quantum yield in the near-infrared range and has a very high molar extinction coefficient.
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- HY-151890
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Fluorescent Dye
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Cancer
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NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .
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- HY-149835
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Fluorescent Dye
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Others
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TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .
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- HY-D2219
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Fluorescent Dye
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Others
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Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .
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- HY-W088089
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Fluorescent Dye
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Cancer
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ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue (Ex/Em = 785/810 nm) .
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- HY-D2227
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Autophagy
Apoptosis
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Cancer
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IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .
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- HY-D1537
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DBCO-Cy5.5; Cyanine5.5 DBCO
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Fluorescent Dye
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Others
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Dibenzocyclooctyne-Cy5.5 (DBCO-Cy5.5) is a fluorescent dye. Dibenzocyclooctyne-Cy5.5 can be used to syntheses calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging .
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- HY-142523
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- HY-P99500
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RM-1929; Cetuximab-IRDye-700DX
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EGFR
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Cancer
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Cetuximab sarotalocan (RM-1929) is an IRdye700DX (near-infrared photosensitizing dye) conjugate of Cetuximab (anti-EGFR monoclonal antibody). Cetuximab sarotalocan can be used for head and neck cancers research .
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- HY-136886
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IR-820
1 Publications Verification
New Indocyanine Green
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Fluorescent Dye
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Cancer
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IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals .
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- HY-P991650
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PSMA
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Cancer
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MDX1201 is a humanized monoclonal antibody targeting PSMA1/7. MDX1201 conjugated with a fluorescent dye AlexaTM488 can be used as a probe for near-infrared fluorescence imaging (NIRF) imaging of prostate cancer .
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- HY-D2197
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Fluorescent Dye
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Others
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AgAuSe-COOH (1120 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .
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- HY-D2196
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Fluorescent Dye
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Others
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AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window.
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- HY-D2279
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Fluorescent Dye
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Inflammation/Immunology
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NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .
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- HY-D2193
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Fluorescent Dye
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Others
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AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .
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- HY-D1324
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Fluorescent Dye
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Others
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Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
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- HY-150979
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Fluorescent Dye
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Cancer
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Gd-NMC-3 is a near-infrared fluorescence/magnetic resonance (NIRF/MR) bimodal imaging probe. Gd-NMC-3 shows high resolution and sensitivity in tumor imaging with good biocompatibility, indicating huge application potential .
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- HY-D1340
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Fluorescent Dye
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Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
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- HY-W248594
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Fluorescent Dye
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Others
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IR 813 tosylate is a near-infrared (NIR) fluorescent dye and can be used for visualizing regional lymph nodes in mice .
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- HY-139824
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Biochemical Assay Reagents
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Cancer
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Nitro-coronene can be used to prepare near-infrared light-triggered lysosome-targetable carbon dots for photothermal research of cancer.
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- HY-133884
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Fluorescent Dye
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Cancer
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ICG amine, as a near-infrared fluorescent probe, binds to amino acid residues without condensing agents. ICG is a tricarbocyanine dye .
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- HY-D1719A
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Fluorescent Dye
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Cancer
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Cypate is a near-infrared fluorescent dye that belongs to the family of photosensitizers. Cypate has high photostability and optical properties, and is often used in near-infrared optical imaging, as well as optical imaging, tumor marking, and drug delivery. In addition, Cypate is also used as a molecular probe and combined with targeting molecules (such as CBT or small interfering RNA) to achieve efficient detection and imaging of specific cells or tissues .
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- HY-D2309
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Fluorescent Dye
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Others
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IRDye700Dx (IRDye 700DX NHS ester) Maleimide is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
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- HY-D1873
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Fluorescent Dye
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Others
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800CW acid is a near-infrared (NIR) dye that can be used for protein labeling. 800CW acid can be used for in vivo imaging studies .
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- HY-170490
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Photosensitizer
Apoptosis
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Cancer
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TTQ-SA is a near-infrared (NIR) spiro-AIEgen (aggregation-induced emission luminogen), that converts near-infrared light (NIR) into thermal energy, causing thermal damage and death of tumor cells. TTQ-SA exhibits cellular uptake and targeting ability in cancer cell MF-7. TTQ-SA silences the expression of survivin gene with combination of DNAzyme, enhances the sensitivity of tumor cells to photothermal therapy .
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- HY-150978
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Fluorescent Dye
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Others
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DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .
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- HY-P6083
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Biochemical Assay Reagents
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Others
Cancer
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RTSPSSR is synthesized peptide, which binds specifically to claudin-1 and visulizes the CRC tumor in mice, through near-infrared fluorescence imaging .
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- HY-D1391
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PbS/CdSe QD
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Fluorescent Dye
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Others
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PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window .
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- HY-D1452
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Fluorescent Dye
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Cancer
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BDP-4 is an amino acid-modified near-infrared Aza-BODIPY photosensitizer, acts as an immune initiator for potent photodynamic research in melanoma .
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- HY-D1375A
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Fluorescent Dye
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Others
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Sulfo-Cy5 amine hydrochloride is a near-infrared (NIR) amino fluorescent dye. Sulfo-Cy5 amine hydrochloride reacts with electrophilic substances .
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- HY-D1535
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Fluorescent Dye
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Others
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IR 813 perchlorate is a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm) and can be used for visualizing regional lymph nodes in mice .
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- HY-D1453
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Biochemical Assay Reagents
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Cancer
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Immune initiator-1 (Compound 1a) is an amino acid-modified near-infrared Aza-BODIPY photosensitizer, acts as an immune initiator for potent photodynamic research in melanoma .
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- HY-D2198
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Fluorescent Dye
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Others
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AgAuSe-PEG-NH2 (1120 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1120 nm that can be used in bioimaging .
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- HY-D1307A
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Fluorescent Dye
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Sulfo-cyanine7 alkyne potassium is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
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- HY-D1307
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Fluorescent Dye
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Sulfo-cyanine7 alkyne is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
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- HY-103242
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Amyloid-β
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Neurological Disease
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CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM .
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- HY-157503
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Photosensitizer
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Cancer
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Photosensitizer-3 is a photosensitizer that exhibits powerful selective killing effects on transfected HEK cells and affibody-targeted A431 cancer cells when exposed to near-infrared light excitation .
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- HY-D2417
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Fluorescent Dye
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Others
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SiRA 2 is a near-infrared (NIR) fluoride used in SiRA illumination aptamers. SiRA 2 is capable of imaging single RNA in living cells with maximum excitation emission wavelength: 649/662 nm .
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- HY-111653
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CycLuc1
2 Publications Verification
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Reactive Oxygen Species (ROS)
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Others
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CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
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- HY-N16309
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Fluorescent Dye
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Others
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Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.
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- HY-D1464
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CH1055
1 Publications Verification
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Fluorescent Dye
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Cancer
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CH1055 is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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- HY-155395
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Fluorescent Dye
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Infection
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DDAN-MT is an enzymatic activated near-infrared fluorescent probe. DDAN-MT can be used for rapid, highly selective, and real-time monitoring of endogenous MtMET-AP1 activity in M. tuberculosis .
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- HY-D1067
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Fluorescent Dye
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Others
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NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .
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- HY-D1464A
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Fluorescent Dye
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Cancer
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CH1055 triethylamine is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 triethylamine can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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- HY-D1724
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Fluorescent Dye
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Cancer
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IR-806 is a near-infrared cyanine liquid crystal dye. IR-806 can be used as a molecular antenna to synthesized nanoprobes (NPs). IR-806 can be used for in vivo imaging studies .
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- HY-156842
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Amyloid-β
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Neurological Disease
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MCAAD-3 is a near-infrared Aβ imaging probe with blood-brain barrier penetrability. MCAAD-3 has a strong affinity for Aβ polymers (Ki >106 nM) and can label Aβ plaques in the brains of transgenic mice .
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- HY-W072147
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Fmoc-L-Ser-OMe
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Amino Acid Derivatives
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Others
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Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor .
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- HY-D0921
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ADS 815EI
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Fluorescent Dye
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Others
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Heptamethine cyanine dye-1 (Compound CyCl) is a cyanine dye (Fmax: 858 nm, in CH2Cl2). Heptamethine cyanine dye-1 can be used to synthesize pH near-infrared fluorescent probes .
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- HY-D1325
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Fluorescent Dye
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Others
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Cyanine5.5 alkyne chloride is an alkynyl-modified near-infrared (NIR) fluorescent dye (Ex=678 nm, Em=694 nm). Cyanine5.5 alkyne chloride can react with azides for click chemistry labeling .
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- HY-P10648
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HER2-targeting peptide
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EGFR
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Cancer
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Herceptide (HER2-targeting peptide) is a HER2-targeting peptide, and can be further conjugated to the near-infrared fluorescent dye indocyanine green (HY-D0711) (ICG) for developing theranostic agents .
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- HY-D1711
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Fluorescent Dye
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Cancer
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MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells .
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- HY-D1504
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Fluorescent Dye
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Others
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IR-797 chloride is a near-infrared (NIR) dye. IR 797 has absorption maxima near 700 nm. IR-797 shows some aggregation-induced-emission (AIE) properties. IR-797 shows shows cytotoxic .
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- HY-D1393
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Pb:Ag2Se
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Fluorescent Dye
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Others
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Pb:Ag2Se QDs (Pb:Ag2Se) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .
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- HY-D2241
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Fluorescent Dye
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Others
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Sulfo-Cy7-DBCO is the water-soluble version of cyanine 7. Sulfo-Cy7-DBCO spectral properties are similar to Cy7. Sulfo-Cy7-DBCO is a near-infrared fluorescent dye .
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- HY-163077
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Reactive Oxygen Species (ROS)
Apoptosis
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Cancer
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Anticancer agent 175 (complex 1) ia a near-infrared (NIR) luminescent theranostic complex. Anticancer agent 175 induces ROS accumulation, mitochondrial damage, disruption of Bax/Bcl-2 equilibrium, and tumor cell apoptosis in HepG2 cell line .
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- HY-D2345
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Fluorescent Dye
Carbonic Anhydrase
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Cancer
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GZ22-4 is a near-infrared (NIR) fluorescent probe. GZ22-4 shows high affinity for carbonic anhydrase IX (CAIX), with a Kd of 0.2 nM. GZ22-4 can be used for the research of visualize CAIX-positive tumors .
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- HY-W835383
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Fluorescent Dye
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Others
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Sulfo-Cy5.5-COOH is a sulfonated Cy5.5 fluorescent dye containing a sulfonic acid group and a carboxylic acid group. The fluorescence wavelength of Sulfo-Cy5.5-COOH is in the near-infrared region and has strong penetrating power.
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- HY-D2328
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Alexa Fluor 680 succinimidyl ester
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Fluorescent Dye
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Others
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Alexa Fluor 680 NHS ester (Alexa Fluor 680 succinimidyl ester) is a near-infrared (NIR) fluorescent dye. NHS esters can be used to label to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 679/702 nm) .
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- HY-D1541
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Fluorescent Dye
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Others
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Sulfo-Cyanine5.5 alkyne, a near-infrared (NIR) fluorescent dye, is an alkyne modified Sulfo-Cyanine5.5 (Ex=67 8nm, Em=694 nm). Sulfo-Cyanine5.5 alkyne can react with azides for Click Chemistry labeling.
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- HY-139109
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ADS 780WS
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Fluorescent Dye
Apoptosis
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Others
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IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer .
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- HY-D1450
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S01448
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Fluorescent Dye
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Cancer
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IR-1048 is a nitroreductase (NTR)-responsive near-infrared fluorescence (NIR)/photoacoustic (PA) imaging probe and photothermal agent. IR-1048 is coupled with a nitroimidazole group to form IR-1048-MZ. IR-1048-MZ is catalytically reduced by NTR in a hypoxic environment, restoring strong near-infrared absorption and fluorescence emission (NIR II window), while activating the photothermal effect. IR-1048 relies on NTR-mediated electron transfer to relieve intramolecular fluorescence quenching, achieving specific imaging and photothermal ablation of tumor hypoxic areas. IR-1048 is mainly used for high-contrast NIR II/photoacoustic imaging and photothermal therapy research and tumor diagnosis of the tumor hypoxic microenvironment .
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- HY-D2328A
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Alexa Fluor 680 succinimidyl ester diTEA
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Fluorescent Dye
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Others
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Alexa Fluor 680 NHS ester (Alexa Fluor 680 succinimidyl ester) diTEA is a near-infrared (NIR) fluorescent dye. NHS esters can be used to label to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 679/702 nm) .
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- HY-155383
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Tau Protein
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Neurological Disease
Cancer
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TNIR7-1A is a fused cycloheptatriene–BODIPY derivative that displays properties favorable for near-infrared (NIR) imaging (Ex/Em = 600/774 nm in PBS) with high affinity and specificity to Neurofibrillary tangles (NFTs) in vitro. TNIR7-1A effectively penetrated the blood–brain barrier .
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- HY-D2880
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Fluorescent Dye
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Others
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Sulfo-Cyanine5 DBCO is a near-infrared red (NIR) fluorescent dye. Sulfo-Cyanine5 DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em =646/670 nm) .
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- HY-114879
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DDAO
1 Publications Verification
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Fluorescent Dye
Carboxylesterase (CES)
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Cancer
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DDAO is a promising near-infrared (NIR) red fluorescent probewith tunable excitation wavelength (600-650nm) and longemission wavelength(λem=656nm). DDAO can de desiged for detection of the activities of different enzymes such asβ-galactosidase,sulfatase, proteinphosphatase2A,carboxylesterase 2, humanalbumin andesterases .
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- HY-112641
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Fluorescent Dye
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Cancer
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AkaLumine is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
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- HY-P10674
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Biochemical Assay Reagents
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Neurological Disease
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QMT-CBT is a near-infrared aggregation-induced luminescent photon. After activation of caspase1 (Cas1), QMT-CBT undergoes a CBT-Cys click reaction to form a cyclic dimer QMT-Dimer (the first aggregate) and assembles into nanoparticles (the second aggregate), turning the AIE signal "on" to enhance imaging of Alzheimer's disease (AD) .
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- HY-112641A
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Fluorescent Dye
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Cancer
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AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
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- HY-149203
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Fluorescent Dye
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Others
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MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO - (λem=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λem>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
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- HY-D2864
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Fluorescent Dye
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Others
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Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
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- HY-D2285
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Fluorescent Dye
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Cancer
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MOR-CES2 is a near-infrared fluorescent probe (Ex= 630 nm, Em=735 nm) capable of identifying cancer cells and tissues, as well as exhibiting a sensitive response to inflammation. MOR-CES2 holds potential as an efficient imaging tool in assisting surgical resection of CES2-related tumors .
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- HY-D2194
-
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Fluorescent Dye
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Others
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AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
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- HY-D2268
-
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Fluorescent Dye
Amyloid-β
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Neurological Disease
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QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
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- HY-D1716
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Fluorescent Dye
Drug Intermediate
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Cancer
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S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .
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-
- HY-D2217
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-
- HY-150971
-
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Pyroptosis
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Cancer
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ICy-Q is a quinone oxidoreductase 1 (NQO-1)-activated near-infrared (NIR) reagent which can react with NQO-1 to release the reduction product ICy-OH. ICy-OH selectively induces pancreatic cancer cell death through the pyroptosis pathway. ICy-Q can be used as an effective tool for rapid and accurate diagnosis of intraoperative pathological sections .
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- HY-D2268A
-
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Amyloid-β
Fluorescent Dye
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Neurological Disease
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|
QM-FN-SO3 ammonium is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 ammonium can be used for in vivo detection of Aβ plaques. QM-FN-SO3 ammonium has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
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- HY-D1719
-
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Fluorescent Dye
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Others
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Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging .
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- HY-D1449
-
-
- HY-142533
-
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Biochemical Assay Reagents
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Cancer
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HL-PEG2k is a second near-infrared Ru(II) polypyridyl complex. HL-PEG2k exhibits a wavelength bathochromic shift, enhanced photothermal conversion efficiency (41.77%), and an antineoplastic effect against glioma. HL-PEG2k displays a superior biocompatibility and thus can be a potential theranostic platform to combat the growth and recurrence of tumors .
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-
- HY-D2189
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IRDye 700DX NHS ester
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Fluorescent Dye
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Others
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IRDye 700DX (IRDye 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye with extremely high photostability and fluorescence intensity. IRDye 700DX binds to biomolecules. IRDye 700DX has excellent water solubility, large extinction coefficient, high fluorescence quantum yield, and does not aggregate in high ionic strength buffers. IRDye 700DX can be used as a highly flexible photosensitizer .
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- HY-D1540
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Cy 5.5 amine; Lumiprobe Cy 5.5 amine
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Fluorescent Dye
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Others
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Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
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- HY-P10788
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Complement System
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Cancer
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CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer.
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- HY-D1865
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Fluorescent Dye
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Others
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Cy3 dimethyl iodide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) with a dimethyl group in the iodide salt form. The iodide salt form increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. Cy3 dimethyl iodide binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-136946
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Fluorescent Dye
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Others
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|
HITCI is a commercially available, positively charged indocarbocyanine dye. HITCI is used typically as a laser dye in the near infrared (NIR) .
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- HY-D1872
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Fluorescent Dye
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Others
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|
800CW NHS ester is a near infrared probe that can be used for labeling lysine residues (λmax=776 nm) .
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-
- HY-D1317A
-
|
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Fluorescent Dye
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Others
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|
Cyanine7.5 carboxylic is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid functional groups. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Cyanine7.5 carboxylic can be covalently bound to some biological molecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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-
- HY-149422
-
|
|
Fluorescent Dye
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Neurological Disease
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|
NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O 2-. O 2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O 2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model .
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-
- HY-149696
-
|
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NF-κB
|
Cancer
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|
IR-Crizotinib is a NF-κB-inducing kinase (NIK) inhibitor that crosses the blood-brain barrier and fluorescently localizes intracranial glioblastoma (GBM) in mice (IC50=3.381 μM). IR-Crizotinib is conjugated from the near-infrared dye IR-786 and the NF-κB-inducing kinase (NIK) inhibitor Crizotinib. IR-Crizotinib can effectively inhibit the growth and invasion of glioma in vitro and in vivo and can be used in cancer research .
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-
- HY-165424
-
|
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Fluorescent Dye
Glycosidase
|
Cardiovascular Disease
Cancer
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|
NIR-BG2 is a near-infrared fluorescent probe targeting senescence-associated β-galactosidase (SA-β-Gal). NIR-BG2 is activated by SA-β-Gal and undergoes hydrolysis to release electrophilic quinone methide that covalently binds to surrounding proteins for in situ labeling, with a 16-fold enhancement of fluorescence signal at 709 nm . NIR-BG2 is promising for research of vivo imaging of cellular senescence .
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-
- HY-D1317
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Fluorescent Dye
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Others
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Cyanine7.5 carboxylic acid chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid functional groups. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Cyanine7.5 carboxylic acid chloride can be covalently bound to some biological molecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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-
- HY-157317
-
|
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Apoptosis
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Cancer
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|
Antitumor agent-126 (Compound II4) is a photoactive (IC50= 0.149) anticancer agent with significant near-infrared fluorescence emission at 650-760 nm. Antitumor agent-126 has antiproliferative activity and can induce apoptosis after laser irradiation. Antitumor agent-126 effectively inhibits tumor growth in mouse xenograft models exposed to 650 nm laser irradiation. Antitumor agent-126 can be used in cancer research .
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-
- HY-D2315
-
|
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Fluorescent Dye
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Cancer
|
|
Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cys (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant 1,4-dimercaptothreitol (DTT) and the inhibitor N-ethylmaleimide (NEM) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .
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-
- HY-175214
-
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Reactive Oxygen Species (ROS)
Photosensitizer
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Cancer
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|
Antitumor photosensitizer-9 is a near-infrared Photosensitizer (PS) with a high singlet oxygen production rate (relative rate = 1.79). Antitumor photosensitizer-9 exhibits strong phototoxicity against various cancer cells and induces ROS generation under light irradiation. Antitumor photosensitizer-9 inhibits tumor growth in vivo and exhibits excellent anticancer photodynamic therapy (PDT) efficacy at low drug and light doses. Antitumor photosensitizer-9 can be used in photodynamic therapy research .
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- HY-D1846
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Fluorescent Dye
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Others
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Sulfo-Cy7.5 dimethyl is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with a dimethyl group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Sulfo-Cy7.5 dimethyl binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1744
-
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Fluorescent Dye
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Others
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|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
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-
- HY-D1174
-
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Fluorescent Dye
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Others
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|
Rhodamine 700, a Lambdachrome laser dye, is one of the few rhodamine dyes with near infrared fluorescence. Rhodamine 700 can be used for mitochondrial staining .
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-
- HY-D1847
-
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Fluorescent Dye
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Others
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|
Cy7.5 tetrazine tetrafluoroborate is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a tetrazine group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Cy7.5 tetrazine tetrafluoroborate can perform efficient click reactions with molecules containing alkyne functional groups (such as alkyne) to form covalent bonds. It can be combined with biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1068
-
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DBCO-Sulfo-Cy5
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Fluorescent Dye
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Others
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Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-W127820
-
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Tetrakis(2-N-methylpyridyl)porphine chloride
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Biochemical Assay Reagents
Fluorescent Dye
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Others
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H2TMpyP-2 (tetrakis(2-N-methylpyridyl)porphine) chloride is an active photosensitizer with strong absorption properties in the visible to near-infrared region and excellent singlet oxygen quantum yield. Captisol-TMPyP complexes can be used in supramolecular nanosynthesis to increase singlet oxygen production, improve photostability and better photosensitization, and support photodynamic therapy activity. The Captisol:TMPyP complex also exhibited antibacterial activity against Escherichia coli and was cytotoxic against lung cancer A549 cells .
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-
- HY-D1500
-
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Fluorescent Dye
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Others
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|
Fluorescent NIR 885 is a cyanine near-infrared-absorbing dye. Fluorescent NIR 885 can be used as a photoprotective agent (extracted from patent WO2014006589 compound 1-35) .
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-
- HY-D1375
-
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Fluorescent Dye
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Others
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|
Sulfo-Cy5 amine is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy5 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. The amine functionality of Sulfo-Cy5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1864
-
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Fluorescent Dye
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Others
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|
Sulfo-Cy7.5 dicarboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 dicarboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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-
- HY-D1308
-
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Fluorescent Dye
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Others
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|
Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D1318
-
|
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Fluorescent Dye
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Others
|
|
Cyanine7.5 azide chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with an azide functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Cyanine7.5 azide chloride can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Cyanine7.5 azide chloride can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1394
-
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AgAuSe
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Fluorescent Dye
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Others
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|
AgAuSe QDs (AgAuSe) is a near infrared (NIR) fluorescent quantum dots (QDs), with a bright emission from 820 to 1170 nm. AgAuSe QDs can be used for the research in biomedical imaging and NIR devices .
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-
- HY-122878
-
|
|
HSP
|
Cancer
|
HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers .
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-
- HY-163465
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
DTNP is a BchE -activated near infrared (NIR) probe with blood-brain permeability. DTNP can be activated by BchE and inhibit its enzyme activity. DTNP can be used in Alzheimer's disease (AD) research .
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-
- HY-D1862
-
|
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Fluorescent Dye
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Others
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|
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1866
-
|
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Fluorescent Dye
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Others
|
|
Sulfo-Cy7.5 carboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate ion (sulfonate) functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 carboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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-
- HY-D1065
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
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-
- HY-149203A
-
|
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Fluorescent Dye
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Others
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|
MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO -, λem=645 nm; and NIR channel at λem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
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-
- HY-W879234
-
|
Sulfo Cy5.5-DBCO
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Fluorescent Dye
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Others
|
|
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.
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-
- HY-D1863
-
|
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Fluorescent Dye
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Others
|
|
sulfo-Cy7.5 amine is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The amine functionality of sulfo-Cy7.5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy7.5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-118924
-
|
|
Fluorescent Dye
|
Cancer
|
|
IR-825 is a near infrared fluorescent dye.the end of IR-825 has carboxyl COOH active group, and can participate in the reaction to connect other molecules. IR-825 can be widely used in tumor photothermal treatment. .
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-
- HY-D1859
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-W250148
-
|
Spirit nigrosine
|
Biochemical Assay Reagents
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Others
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|
Solvent black 5 (Spirit nigrosine) is a synthetic dye belonging to the family of azo dyes. Also known as oil black or naphthol black, it is dark blue-black and has excellent solubility in organic solvents. Solvent black 5 is commonly used as a colorant in various industrial applications such as printing inks, coatings and plastics. It can also be used as an indicator dye to detect the presence of metals in solution. Furthermore, due to its high absorption and emission properties in the near-infrared region, it has been used in scientific research as a fluorescent biomarker for tissues and cells. However, Solvent black 5 has been reported to have potentially toxic effects on human health and the environment and its use is therefore regulated in some countries.
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-
- HY-W879007
-
|
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Fluorescent Dye
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Others
|
|
ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
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-
- HY-151757
-
|
|
Fluorescent Dye
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Others
|
|
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .
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-
- HY-151753
-
|
|
Fluorescent Dye
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Others
|
|
Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
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-
- HY-D1568
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .
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-
- HY-D2448
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG-Thiol (Cy3-PEG-SH) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-Thiol is absorbed at 550nm and has high solubility and end-group substitution rate .
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-
- HY-D2510
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG-SH (MW 2000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 2000) is absorbed at 550nm and has high solubility and end-group substitution rate .
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-
- HY-D1568A
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy7.5 NHS ester tripotassium is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester tripotassium contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester tripotassium can be used for the research of NIR imaging applications .
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-
- HY-D2513
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG-SH (MW 10000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 10000) is absorbed at 550nm and has high solubility and end-group substitution rate .
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-
- HY-D2511
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG-SH (MW 3400) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 3400) is absorbed at 550nm and has high solubility and end-group substitution rate .
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-
- HY-D1850
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D1376
-
|
|
Fluorescent Dye
|
|
|
Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.
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-
- HY-P5520
-
|
|
Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
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-
- HY-P10052
-
|
|
VEGFR
|
Cancer
|
|
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling .
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- HY-D1600
-
|
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Fluorescent Dye
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Others
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|
Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
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| Cat. No. |
Product Name |
Type |
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- HY-W588722
-
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Fluorescent Dyes/Probes
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|
ICG-DBCO is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 789/813 nm
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-
- HY-D2195
-
|
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Fluorescent Dyes/Probes
|
|
AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.
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-
- HY-D1041
-
|
ICG NHS ester
|
Fluorescent Dyes/Probes
|
|
ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .
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-
- HY-139579
-
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OTL 38
|
Fluorescent Dyes/Probes
|
|
Pafolacianine (OTL 38) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine excites at 774 to 775 nm and emits at 794 to 796 nm .
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-
- HY-D2312
-
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Fluorescent Dyes/Probes
|
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Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) .
|
-
- HY-D1463
-
|
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Fluorescent Dyes/Probes
|
|
Nile Blue Methacrylamide is a Nile Blue-based nanosized pH densor that can be used for simultaneous far-red and near-infrared live bioimaging .
|
-
- HY-D2280
-
|
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Fluorescent Dyes/Probes
|
|
Estrogen receptor β/HDAC probe 1 (compound P1) is a near-infrared fluorescent probe that dual-targets the estrogen receptor (Estrogen Receptor/ERR) β/histone deacetylase HDAC .
|
-
- HY-D1367
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cyanine7 carboxylic acid is a highly hydrophilic and water-soluble near-infrared dye. It improves quantum yield in the near-infrared range and has a very high molar extinction coefficient.
|
-
- HY-151890
-
|
|
Fluorescent Dyes/Probes
|
|
NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .
|
-
- HY-149835
-
|
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Fluorescent Dyes/Probes
|
|
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .
|
-
- HY-D2219
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .
|
-
- HY-W088089
-
|
|
Fluorescent Dyes/Probes
|
|
ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue (Ex/Em = 785/810 nm) .
|
-
- HY-D2227
-
|
|
Fluorescent Dyes/Probes
|
|
IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .
|
-
- HY-D1537
-
|
DBCO-Cy5.5; Cyanine5.5 DBCO
|
Fluorescent Dyes/Probes
|
|
Dibenzocyclooctyne-Cy5.5 (DBCO-Cy5.5) is a fluorescent dye. Dibenzocyclooctyne-Cy5.5 can be used to syntheses calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging .
|
-
- HY-136886
-
IR-820
1 Publications Verification
New Indocyanine Green
|
Fluorescent Dyes/Probes
|
|
IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals .
|
-
- HY-D2197
-
|
|
Fluorescent Dyes/Probes
|
|
AgAuSe-COOH (1120 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .
|
-
- HY-D2196
-
|
|
Fluorescent Dyes/Probes
|
|
AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window.
|
-
- HY-D2279
-
|
|
Fluorescent Dyes/Probes
|
|
NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .
|
-
- HY-D2193
-
|
|
Fluorescent Dyes/Probes
|
|
AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .
|
-
- HY-D1324
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
|
-
- HY-150979
-
|
|
Fluorescent Dyes/Probes
|
|
Gd-NMC-3 is a near-infrared fluorescence/magnetic resonance (NIRF/MR) bimodal imaging probe. Gd-NMC-3 shows high resolution and sensitivity in tumor imaging with good biocompatibility, indicating huge application potential .
|
-
- HY-D1340
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
|
-
- HY-D2309
-
|
|
Dyes
|
|
IRDye700Dx (IRDye 700DX NHS ester) Maleimide is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
|
-
- HY-D1873
-
|
|
Fluorescent Dyes/Probes
|
|
800CW acid is a near-infrared (NIR) dye that can be used for protein labeling. 800CW acid can be used for in vivo imaging studies .
|
-
- HY-150978
-
|
|
Fluorescent Dyes/Probes
|
|
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .
|
-
- HY-D1391
-
|
PbS/CdSe QD
|
Quantum Dots
|
|
PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window .
|
-
- HY-D1375A
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy5 amine hydrochloride is a near-infrared (NIR) amino fluorescent dye. Sulfo-Cy5 amine hydrochloride reacts with electrophilic substances .
|
-
- HY-D1535
-
|
|
Fluorescent Dyes/Probes
|
|
IR 813 perchlorate is a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm) and can be used for visualizing regional lymph nodes in mice .
|
-
- HY-D2198
-
|
|
Fluorescent Dyes/Probes
|
|
AgAuSe-PEG-NH2 (1120 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1120 nm that can be used in bioimaging .
|
-
- HY-D1307A
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-cyanine7 alkyne potassium is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
-
- HY-D1307
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-cyanine7 alkyne is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
-
- HY-D2417
-
|
|
Dyes
|
|
SiRA 2 is a near-infrared (NIR) fluoride used in SiRA illumination aptamers. SiRA 2 is capable of imaging single RNA in living cells with maximum excitation emission wavelength: 649/662 nm .
|
-
- HY-111653
-
CycLuc1
2 Publications Verification
|
Chromogenic Substrates
|
|
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
|
-
- HY-D1067
-
|
|
Fluorescent Dyes/Probes
|
|
NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .
|
-
- HY-D0921
-
|
ADS 815EI
|
Fluorescent Dyes/Probes
|
|
Heptamethine cyanine dye-1 (Compound CyCl) is a cyanine dye (Fmax: 858 nm, in CH2Cl2). Heptamethine cyanine dye-1 can be used to synthesize pH near-infrared fluorescent probes .
|
-
- HY-D1325
-
|
|
Dyes
|
|
Cyanine5.5 alkyne chloride is an alkynyl-modified near-infrared (NIR) fluorescent dye (Ex=678 nm, Em=694 nm). Cyanine5.5 alkyne chloride can react with azides for click chemistry labeling .
|
-
- HY-D1711
-
|
|
Dyes
|
|
MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells .
|
-
- HY-D1504
-
|
|
Dyes
|
|
IR-797 chloride is a near-infrared (NIR) dye. IR 797 has absorption maxima near 700 nm. IR-797 shows some aggregation-induced-emission (AIE) properties. IR-797 shows shows cytotoxic .
|
-
- HY-D1393
-
|
Pb:Ag2Se
|
Quantum Dots
|
|
Pb:Ag2Se QDs (Pb:Ag2Se) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .
|
-
- HY-D2241
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy7-DBCO is the water-soluble version of cyanine 7. Sulfo-Cy7-DBCO spectral properties are similar to Cy7. Sulfo-Cy7-DBCO is a near-infrared fluorescent dye .
|
-
- HY-D2345
-
|
|
Fluorescent Dyes/Probes
|
|
GZ22-4 is a near-infrared (NIR) fluorescent probe. GZ22-4 shows high affinity for carbonic anhydrase IX (CAIX), with a Kd of 0.2 nM. GZ22-4 can be used for the research of visualize CAIX-positive tumors .
|
-
- HY-D2328
-
|
Alexa Fluor 680 succinimidyl ester
|
Dyes
|
|
Alexa Fluor 680 NHS ester (Alexa Fluor 680 succinimidyl ester) is a near-infrared (NIR) fluorescent dye. NHS esters can be used to label to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 679/702 nm) .
|
-
- HY-D1541
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cyanine5.5 alkyne, a near-infrared (NIR) fluorescent dye, is an alkyne modified Sulfo-Cyanine5.5 (Ex=67 8nm, Em=694 nm). Sulfo-Cyanine5.5 alkyne can react with azides for Click Chemistry labeling.
|
-
- HY-D2328A
-
|
Alexa Fluor 680 succinimidyl ester diTEA
|
Dyes
|
|
Alexa Fluor 680 NHS ester (Alexa Fluor 680 succinimidyl ester) diTEA is a near-infrared (NIR) fluorescent dye. NHS esters can be used to label to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 679/702 nm) .
|
-
- HY-D2880
-
|
|
Dyes
|
|
Sulfo-Cyanine5 DBCO is a near-infrared red (NIR) fluorescent dye. Sulfo-Cyanine5 DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em =646/670 nm) .
|
-
- HY-114879
-
DDAO
1 Publications Verification
|
Fluorescent Dyes/Probes
|
|
DDAO is a promising near-infrared (NIR) red fluorescent probewith tunable excitation wavelength (600-650nm) and longemission wavelength(λem=656nm). DDAO can de desiged for detection of the activities of different enzymes such asβ-galactosidase,sulfatase, proteinphosphatase2A,carboxylesterase 2, humanalbumin andesterases .
|
-
- HY-112641
-
|
|
Chromogenic Substrates
|
|
AkaLumine is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
|
-
- HY-112641A
-
|
|
Chromogenic Substrates
|
|
AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
|
-
- HY-149203
-
|
|
Fluorescent Dyes/Probes
|
|
MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO - (λem=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λem>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
|
-
- HY-D2864
-
|
|
Fluorescent Dyes/Probes
|
|
Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
|
- HY-D2285
-
|
|
Fluorescent Dyes/Probes
|
|
MOR-CES2 is a near-infrared fluorescent probe (Ex= 630 nm, Em=735 nm) capable of identifying cancer cells and tissues, as well as exhibiting a sensitive response to inflammation. MOR-CES2 holds potential as an efficient imaging tool in assisting surgical resection of CES2-related tumors .
|
- HY-D2194
-
|
|
Fluorescent Dyes/Probes
|
|
AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
|
- HY-D2268
-
|
|
Fluorescent Dyes/Probes
|
|
QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
|
- HY-D1716
-
|
|
Fluorescent Dyes/Probes
|
|
S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .
|
- HY-D2217
-
- HY-D2268A
-
|
|
Fluorescent Dyes/Probes
|
|
QM-FN-SO3 ammonium is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 ammonium can be used for in vivo detection of Aβ plaques. QM-FN-SO3 ammonium has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
|
- HY-D2189
-
|
IRDye 700DX NHS ester
|
Dyes
|
|
IRDye 700DX (IRDye 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye with extremely high photostability and fluorescence intensity. IRDye 700DX binds to biomolecules. IRDye 700DX has excellent water solubility, large extinction coefficient, high fluorescence quantum yield, and does not aggregate in high ionic strength buffers. IRDye 700DX can be used as a highly flexible photosensitizer .
|
- HY-D1540
-
|
Cy 5.5 amine; Lumiprobe Cy 5.5 amine
|
Fluorescent Dyes/Probes
|
|
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
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- HY-D1865
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 dimethyl iodide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) with a dimethyl group in the iodide salt form. The iodide salt form increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. Cy3 dimethyl iodide binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-D1872
-
|
|
Fluorescent Dyes/Probes
|
|
800CW NHS ester is a near infrared probe that can be used for labeling lysine residues (λmax=776 nm) .
|
- HY-D1317A
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine7.5 carboxylic is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid functional groups. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Cyanine7.5 carboxylic can be covalently bound to some biological molecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
- HY-149696
-
|
|
Dyes
|
|
IR-Crizotinib is a NF-κB-inducing kinase (NIK) inhibitor that crosses the blood-brain barrier and fluorescently localizes intracranial glioblastoma (GBM) in mice (IC50=3.381 μM). IR-Crizotinib is conjugated from the near-infrared dye IR-786 and the NF-κB-inducing kinase (NIK) inhibitor Crizotinib. IR-Crizotinib can effectively inhibit the growth and invasion of glioma in vitro and in vivo and can be used in cancer research .
|
- HY-D2315
-
|
|
Fluorescent Dyes/Probes
|
|
Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cys (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant 1,4-dimercaptothreitol (DTT) and the inhibitor N-ethylmaleimide (NEM) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .
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- HY-D1846
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy7.5 dimethyl is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with a dimethyl group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Sulfo-Cy7.5 dimethyl binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-D1744
-
|
|
Fluorescent Dyes/Probes
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
|
- HY-D1174
-
|
|
Dyes
|
|
Rhodamine 700, a Lambdachrome laser dye, is one of the few rhodamine dyes with near infrared fluorescence. Rhodamine 700 can be used for mitochondrial staining .
|
- HY-D1847
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5 tetrazine tetrafluoroborate is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a tetrazine group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Cy7.5 tetrazine tetrafluoroborate can perform efficient click reactions with molecules containing alkyne functional groups (such as alkyne) to form covalent bonds. It can be combined with biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-D1068
-
|
DBCO-Sulfo-Cy5
|
Fluorescent Dyes/Probes
|
|
Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-D1500
-
|
|
Fluorescent Dyes/Probes
|
|
Fluorescent NIR 885 is a cyanine near-infrared-absorbing dye. Fluorescent NIR 885 can be used as a photoprotective agent (extracted from patent WO2014006589 compound 1-35) .
|
- HY-D1375
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy5 amine is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy5 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. The amine functionality of Sulfo-Cy5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-D1864
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy7.5 dicarboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 dicarboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
- HY-D1308
-
|
|
Dyes
|
|
Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D1318
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine7.5 azide chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with an azide functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Cyanine7.5 azide chloride can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Cyanine7.5 azide chloride can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-D1394
-
|
AgAuSe
|
Quantum Dots
|
|
AgAuSe QDs (AgAuSe) is a near infrared (NIR) fluorescent quantum dots (QDs), with a bright emission from 820 to 1170 nm. AgAuSe QDs can be used for the research in biomedical imaging and NIR devices .
|
- HY-122878
-
|
|
Fluorescent Dyes/Probes
|
HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers .
|
- HY-D1862
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-D1866
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Fluorescent Dyes/Probes
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Sulfo-Cy7.5 carboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate ion (sulfonate) functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 carboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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- HY-D1065
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Fluorescent Dyes/Probes
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NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
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- HY-W879234
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Sulfo Cy5.5-DBCO
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Fluorescent Dyes/Probes
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TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.
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- HY-D1863
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Fluorescent Dyes/Probes
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sulfo-Cy7.5 amine is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The amine functionality of sulfo-Cy7.5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy7.5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-118924
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Fluorescent Dyes/Probes
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IR-825 is a near infrared fluorescent dye.the end of IR-825 has carboxyl COOH active group, and can participate in the reaction to connect other molecules. IR-825 can be widely used in tumor photothermal treatment. .
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- HY-D1859
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Fluorescent Dyes/Probes
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Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-W250148
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Spirit nigrosine
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Dyes
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Solvent black 5 (Spirit nigrosine) is a synthetic dye belonging to the family of azo dyes. Also known as oil black or naphthol black, it is dark blue-black and has excellent solubility in organic solvents. Solvent black 5 is commonly used as a colorant in various industrial applications such as printing inks, coatings and plastics. It can also be used as an indicator dye to detect the presence of metals in solution. Furthermore, due to its high absorption and emission properties in the near-infrared region, it has been used in scientific research as a fluorescent biomarker for tissues and cells. However, Solvent black 5 has been reported to have potentially toxic effects on human health and the environment and its use is therefore regulated in some countries.
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- HY-W879007
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Fluorescent Dyes/Probes
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ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
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- HY-151757
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Fluorescent Dyes/Probes
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Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .
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- HY-151753
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Fluorescent Dyes/Probes
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Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
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- HY-D1568
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Dyes
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Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .
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- HY-D2448
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Fluorescent Dyes/Probes
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Cy3-PEG-Thiol (Cy3-PEG-SH) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-Thiol is absorbed at 550nm and has high solubility and end-group substitution rate .
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- HY-D2510
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Fluorescent Dyes/Probes
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Cy3-PEG-SH (MW 2000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 2000) is absorbed at 550nm and has high solubility and end-group substitution rate .
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- HY-D1568A
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Dyes
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Sulfo-Cy7.5 NHS ester tripotassium is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester tripotassium contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester tripotassium can be used for the research of NIR imaging applications .
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- HY-D2513
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Fluorescent Dyes/Probes
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Cy3-PEG-SH (MW 10000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 10000) is absorbed at 550nm and has high solubility and end-group substitution rate .
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- HY-D2511
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Fluorescent Dyes/Probes
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Cy3-PEG-SH (MW 3400) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 3400) is absorbed at 550nm and has high solubility and end-group substitution rate .
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- HY-D1850
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Fluorescent Dyes/Probes
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Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D1376
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Fluorescent Dyes/Probes
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Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.
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- HY-D1600
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Dyes
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Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
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| Cat. No. |
Product Name |
Type |
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- HY-139109
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ADS 780WS
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Indicators
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IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P6083
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Biochemical Assay Reagents
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Others
Cancer
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RTSPSSR is synthesized peptide, which binds specifically to claudin-1 and visulizes the CRC tumor in mice, through near-infrared fluorescence imaging .
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- HY-W072147
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Fmoc-L-Ser-OMe
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Amino Acid Derivatives
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Others
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Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor .
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- HY-P10648
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HER2-targeting peptide
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EGFR
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Cancer
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Herceptide (HER2-targeting peptide) is a HER2-targeting peptide, and can be further conjugated to the near-infrared fluorescent dye indocyanine green (HY-D0711) (ICG) for developing theranostic agents .
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- HY-P10674
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Biochemical Assay Reagents
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Neurological Disease
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QMT-CBT is a near-infrared aggregation-induced luminescent photon. After activation of caspase1 (Cas1), QMT-CBT undergoes a CBT-Cys click reaction to form a cyclic dimer QMT-Dimer (the first aggregate) and assembles into nanoparticles (the second aggregate), turning the AIE signal "on" to enhance imaging of Alzheimer's disease (AD) .
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- HY-P10788
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Complement System
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Cancer
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CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer.
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- HY-P5520
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Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
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Cancer
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GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
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- HY-P10052
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VEGFR
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Cancer
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CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P99500
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RM-1929; Cetuximab-IRDye-700DX
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EGFR
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Cancer
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Cetuximab sarotalocan (RM-1929) is an IRdye700DX (near-infrared photosensitizing dye) conjugate of Cetuximab (anti-EGFR monoclonal antibody). Cetuximab sarotalocan can be used for head and neck cancers research .
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- HY-P991650
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PSMA
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Cancer
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MDX1201 is a humanized monoclonal antibody targeting PSMA1/7. MDX1201 conjugated with a fluorescent dye AlexaTM488 can be used as a probe for near-infrared fluorescence imaging (NIRF) imaging of prostate cancer .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N16309
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Structural Classification
Lipid
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Fluorescent Dye
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Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.
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-
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- HY-165424
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| Cat. No. |
Product Name |
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Classification |
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- HY-W588722
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DBCO
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ICG-DBCO is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 789/813 nm
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- HY-D1325
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Alkynes
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Cyanine5.5 alkyne chloride is an alkynyl-modified near-infrared (NIR) fluorescent dye (Ex=678 nm, Em=694 nm). Cyanine5.5 alkyne chloride can react with azides for click chemistry labeling .
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- HY-D2241
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DBCO
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Sulfo-Cy7-DBCO is the water-soluble version of cyanine 7. Sulfo-Cy7-DBCO spectral properties are similar to Cy7. Sulfo-Cy7-DBCO is a near-infrared fluorescent dye .
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- HY-D2880
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DBCO
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Sulfo-Cyanine5 DBCO is a near-infrared red (NIR) fluorescent dye. Sulfo-Cyanine5 DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em =646/670 nm) .
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- HY-D1068
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DBCO-Sulfo-Cy5
|
|
Labeling and Fluorescence Imaging
DBCO
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Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-D2219
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Tetrazine
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|
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .
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-
- HY-D1307A
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Alkynes
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Sulfo-cyanine7 alkyne potassium is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
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-
- HY-D1307
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Alkynes
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Sulfo-cyanine7 alkyne is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
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-
- HY-D2217
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Tetrazine
|
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Cy7 tetrazine is a near infrared dye that can be used for in vivo imaging .
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-
- HY-D1308
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Azide
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Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D1862
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|
|
Alkynes
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|
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-W879234
-
|
Sulfo Cy5.5-DBCO
|
|
DBCO
|
|
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.
|
-
- HY-D1859
-
|
|
|
Alkynes
|
|
Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-W879007
-
|
|
|
Azide
|
|
ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
|
-
- HY-151757
-
|
|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .
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-
- HY-151753
-
|
|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
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-
- HY-D1850
-
|
|
|
Azide
|
|
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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