nanog

By Targets:	Apoptosis (3) MDM-2/p53 (1) Oct3/4 (4) RAR/RXR (1) Reactive Oxygen Species (ROS) (1) Small Interfering RNA (siRNA) (3) STAT (1) TET Protein (1)
By Research Areas:	Cancer (5) Inflammation/Immunology (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18772

O4I2	Oct3/4	Others
O4I2 is a potent Oct3/4 inducer. O4I2 induces the expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1 .

HY-12303

OAC1 1 Publications Verification	Oct3/4 TET Protein	Cancer
OAC1 is a potent Oct4 activator. OAC1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. OAC1 activates OCT4 through upregulation of HOXB4 expression. OAC1 increases transcription of the Oct4-Nanog-Sox2 triad and TET1. OAC1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time .

HY-17602

Amcasertib BBI503	Apoptosis	Cancer
Amcasertib (BBI503) is an orally activate cancer stemness kinase inhibitor that enhances apoptosis. Amcasertib inhibits the expression of *NANOG* and CD133 and cell viability in PC-9/GR cells.

HY-119672

Oct4 inducer-1	Oct3/4	Others
Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time .

HY-RS26216

Nanog Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nanog Rat Pre-designed siRNA Set A contains three designed siRNAs for Nanog gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nanog Rat Pre-designed siRNA Set A Nanog Rat Pre-designed siRNA Set A

HY-RS19720

Nanog Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nanog Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nanog gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nanog Mouse Pre-designed siRNA Set A Nanog Mouse Pre-designed siRNA Set A

HY-RS09019

NANOG Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NANOG Human Pre-designed siRNA Set A contains three designed siRNAs for NANOG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NANOG Human Pre-designed siRNA Set A NANOG Human Pre-designed siRNA Set A

HY-168885

ZSH-512	Apoptosis RAR/RXR	Cancer
ZSH-512 is a potent RARγ inhibitor. ZSH-512 shows antiproliferation activity. ZSH-512 induces apoptosis. ZSH-512 decreases CD133, NANOG, SOX2, and EPCAM protein expression. ZSH-512 shows anticancer activity. ZSH-512 has the potential for the research of colorectal cancer .

HY-119666

Rooperol	Apoptosis Reactive Oxygen Species (ROS) MDM-2/p53 Oct3/4	Inflammation/Immunology Cancer
Rooperol is a norlignan analog with antitumor, anti-inflammatory, and antioxidant activities. Rooperol induces apoptosis in CSCs through a mitochondrial-induced increase in ROS and a p53-dependent pathway, while also downregulating the expression of key stem cell regulatory factors, such as Oct4, *Nanog, and Sox2*, ultimately exerting its anticancer effects .

HY-N15201

Betavulgarin	STAT	Cancer
Betavulgarin is an anticancer agent. Betavulgarin can be isolated from Sugar Beet (Beta vulgaris). Betavulgarin suppresses the proliferation, migration, colony formation, and mammosphere formation of breast cancer cells, and reduces the size of the CD44 ⁺/CD24 ⁻ subpopulation and the expression of the self-renewal- related genes C-Myc, Nanog and Oct4. Betavulgarin promotes BCSCs death through the regulation of Stat3/Sox2 signaling .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N15201

Betavulgarin	Structural Classification Natural Products Terpenoids Source classification Diterpenoids Beta vulgaris Linn. Plants Chenopodiaceae	STAT
Betavulgarin is an anticancer agent. Betavulgarin can be isolated from Sugar Beet (Beta vulgaris). Betavulgarin suppresses the proliferation, migration, colony formation, and mammosphere formation of breast cancer cells, and reduces the size of the CD44 ⁺/CD24 ⁻ subpopulation and the expression of the self-renewal- related genes C-Myc, Nanog and Oct4. Betavulgarin promotes BCSCs death through the regulation of Stat3/Sox2 signaling .

Cat. No.	Compare	Product Name	Species	Source

HY-P7391

	NANOG Protein, Human (His-SUMO) rHunanog-TAT; Homeobox protein nanog	Human	E. coli
	NANOG Protein, Human (His-SUMO) which functions to maintain the undifferentiated state of pluripotent stem cells.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80237

	Nanog Antibody (YA275)	WB, ICC/IF, FC, IHC-P	Human, Mouse
	Nanog Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 35 kDa, targeting to Nanog. It can be used for WB,ICC/IF,FC,IHC-P assays with tag free, in the background of Human, Mouse.

HY-P85292

	Nanog Antibody (YA4984) nanog; Homeobox protein nanog; Homeobox transcription factor nanog; hnanog	WB, ICC/IF, ELISA	Human
	Nanog Antibody (YA4984) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Nanog. It can be applicated for WB, ICC/IF, ELISA assays, in the background of human.

HY-P86599

	Nanog Antibody (YA6291) nanog; Homeobox protein nanog; Homeobox transcription factor nanog; hnanog	WB, IHC-P, ICC/IF, IP, ELISA	Human
	Nanog Antibody (YA6291) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nanog. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human.

HY-P84804

	NANOG Antibody (YA4501) nanog	WB, ICC/IF, ELISA	Human
	NANOG Antibody (YA4501) is a mouse-derived and non-conjugated IgG1 antibody, targeting to NANOG. It can be applicated for WB, ICC/IF, ELISA assays, in the background of human.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS26216

Nanog Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Nanog Rat Pre-designed siRNA Set A contains three designed siRNAs for Nanog gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS19720

Nanog Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Nanog Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nanog gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS09019

NANOG Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
NANOG Human Pre-designed siRNA Set A contains three designed siRNAs for NANOG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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