2. Search Result
Search Result
Results for "

mismatch repair

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Natural
Products

1

Recombinant Proteins

1

Isotope-Labeled Compounds

8

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116887
    N6-Methyladenine

    		Endogenous Metabolite Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Cancer
    N6-Methyladenine is a modified purine that is widely present in prokaryotes. In prokaryotes, N6-Methyladenine plays an important role in distinguishing host DNA from exogenous DNA and controls many biological functions, such as DNA replication, transcription, mismatch repair, and chromosome replication .
    N6-Methyladenine
  • HY-164496
    KL-50

    		DNA/RNA Synthesis Cancer
    KL-50 is a selective toxin toward tumors that lack the DNA repair protein O 6-methylguanine-DNA-methyltransferase (MGMT), which reverses the formation of O 6-alkylguanine lesions. KL-50 activates DNA damage response pathways and cycle arrest in MGMT-cells, independent of mismatch repair (MMR). KL-50 is promising for research of brain tumors that lack the DNA repair protein MGMT .
    KL-50
  • HY-156581
    WRN inhibitor 5

    		DNA/RNA Synthesis Cancer
    WRN inhibitor 5, a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 5 can be used for the research of cancer, including cancers characterized by microsatellite instability (MSI) and/or defective DNA mismatch repair system (dMMR) .
    WRN inhibitor 5
  • HY-17364
    Temozolomide
    130+ Cited Publications

    NSC 362856; CCRG 81045; TMZ

    		 DNA Alkylator/Crosslinker Autophagy Apoptosis Cancer
    Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects .
    Temozolomide
  • HY-17364S
    Temozolomide-d3

    		DNA Alkylator/Crosslinker Autophagy Apoptosis Cancer
    Temozolomide-d3 is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects .
    Temozolomide-d3
  • HY-116887R
    N6-Methyladenine (Standard)

    		Endogenous Metabolite Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Cancer
    N6-Methyladenine (Standard) is the analytical standard of N6-Methyladenine. This product is intended for research and analytical applications. N6-Methyladenine is a modified purine that is widely present in prokaryotes. In prokaryotes, N6-Methyladenine plays an important role in distinguishing host DNA from exogenous DNA and controls many biological functions, such as DNA replication, transcription, mismatch repair, and chromosome replication .
    N6-Methyladenine (Standard)
  • HY-17364R
    Temozolomide (Standard)

    NSC 362856 (Standard); CCRG 81045 (Standard); TMZ (Standard)

    		 Reference Standards DNA Alkylator/Crosslinker Autophagy Apoptosis Cancer
    Temozolomide (Standard) is the analytical standard of Temozolomide. This product is intended for research and analytical applications. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects .
    Temozolomide (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: