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Results for "

iron dependent lipid peroxidation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	VDAC (1) Enterovirus (1) Ferroptosis (1) Lipoxygenase (2) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Inflammation/Immunology (3)

Inhibitors & Agonists

Screening Libraries

Targets Recommended: Ferroportin Apical Sodium-Dependent Bile Acid Transporter CaMK CDK PKG SNIPERs DNA-PK VDAC SGLT CDKL PDK-1 Pyruvate Oxidase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-120303

LY269415	Lipoxygenase	Inflammation/Immunology
LY269415, is an anti-oxidant agent, is a potent and orally active iron dependent lipid peroxidation and 5-lipoxygenase enzyme inhibitor. LY269415 has anti-inflammatory effects .

HY-114565

LY221068	Lipoxygenase Enterovirus	Inflammation/Immunology
LY221068 is an anti-oxidant and an orally active, potent inhibitor of iron-dependent **lipid peroxidation and 5-lipoxygenase** with antiinflammatory properties. LY221068 inhibits bone damage and paw swelling in the Freund's Complete adjuvant (HY-153808) induced arthritis (FCA) model of rats. LY221068 is promising for research of arthritis .

HY-176212

Ferroptosis-IN-20	Ferroptosis VDAC Reactive Oxygen Species (ROS)	Inflammation/Immunology
Ferroptosis-IN-20 (Compound 34a) is a Ferroptosis inhibitor (EC₅₀: 24.2 nM) targeting *voltage-dependent* anion channel (VDAC)*. Ferroptosis-IN-20 inhibits VDAC oligomerization and lipid* peroxidation. Ferroptosis-IN-20 reduces content of ROS, attenuates TFR1-mediated iron uptake, inhibits Fe ²⁺ level and restores glutathione (GSH) level. Ferroptosis-IN-20 alleviates Folic acid (HY-16637)-induced acute kidney injury (AKI) .

Cat. No.	Product Name

HY-L051

Ferroptosis Compound Library	990 compounds
Ferroptosis is a novel type of cell death program that is distinct from apoptosis, necroptosis and autophagy. It is dependent on iron and reactive oxygen species (ROS) and is characterized by lipid peroxidation. As a novel type of cell death, ferroptosis has distinct properties and recognizing functions involved in physical conditions or various diseases including cancers, neurodegenerative diseases, acute renal failure, etc. MCE carefully collected a unique collection of 990 ferroptosis signaling pathway related compounds with ferroptosis-inducing or -inhibitory activity. MCE Ferroptosis Compound Library is a useful tool to study ferroptosis mechanism as well as related diseases.

Ferroptosis Compound Library

990 compounds

Ferroptosis is a novel type of cell death program that is distinct from apoptosis, necroptosis and autophagy. It is dependent on iron and reactive oxygen species (ROS) and is characterized by lipid peroxidation. As a novel type of cell death, ferroptosis has distinct properties and recognizing functions involved in physical conditions or various diseases including cancers, neurodegenerative diseases, acute renal failure, etc.

MCE carefully collected a unique collection of 990 ferroptosis signaling pathway related compounds with ferroptosis-inducing or -inhibitory activity. MCE Ferroptosis Compound Library is a useful tool to study ferroptosis mechanism as well as related diseases.

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