Search Result
Results for "
iodinated
" in MedChemExpress (MCE) Product Catalog:
3
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B0684
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B-15000; SQ-13396
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Biochemical Assay Reagents
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Cancer
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Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
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- HY-B0307
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Idoxuridine
Maximum Cited Publications
6 Publications Verification
5-Iodo-2′-deoxyuridine; 5-IUdR; IdUrd
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Phosphatase
Orthopoxvirus
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Infection
Cancer
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Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.
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- HY-B1664
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- HY-75839
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- HY-133667
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Apoptosis
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Cancer
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Bromoiodoacetamide is a kind of iodinated haloacetamides (I-HAcAms), with cytotoxicity. Bromoiodoacetamide induces cytotoxicity by via reactive oxygen species (ROS) accumulation and apoptosis in HepG-2 cells .
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- HY-150970
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Pyroptosis
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Cancer
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ICy-OH, an iodinated photosensitizer, is an effective anticancer agent. ICy-OH can be used not only for deep tissue imaging (λex=640 nm,λem=690-740 nm) but also to selectively induce cell death in pancreatic cancer cells via cell pyroptosis pathway .
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- HY-B0684R
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Biochemical Assay Reagents
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Cancer
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Iopamidol (Standard) is the analytical standard of Iopamidol. This product is intended for research and analytical applications. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
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- HY-B0307A
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5-Iodo-2′-deoxyuridine hydrate; 5-IUdR hydrate; IdUrd hydrate
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Phosphatase
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Infection
Cancer
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Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) hydrate is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM .
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- HY-B0307R
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Phosphatase
Orthopoxvirus
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Infection
Cancer
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Idoxuridine (Standard) is the analytical standard of Idoxuridine. This product is intended for research and analytical applications. Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.
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- HY-133657
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- HY-B1292
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Adipiodone
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Drug Derivative
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Others
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Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging.
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- HY-125695
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-
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- HY-122326
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- HY-W586331
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Ligands for E3 Ligase
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Cancer
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Thalidomide-iodo is an iodinated E3 ligase activator. Thalidomide-iodo can be used for further derivitization by substitution of iodine.
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- HY-B1664R
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Thyroid Hormone Receptor
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Endocrinology
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Iopanoic acid (Standard) is the analytical standard of Iopanoic acid. This product is intended for research and analytical applications. Iopanoic acid is an inhibitor of 5'-Deiodinase and also an iodinated contrast medium.
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- HY-75839R
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Potassium Channel
Autophagy
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Cardiovascular Disease
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Dronedarone (Hydrochloride) (Standard) is the analytical standard of Dronedarone (Hydrochloride). This product is intended for research and analytical applications. Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na +, K + and Ca 2+ currents.
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- HY-B1292R
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Drug Derivative
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Others
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Iodipamide (Standard) is the analytical standard of Iodipamide. This product is intended for research and analytical applications. Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging.
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- HY-B0926A
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Diatrizoic acid sodium salt; Sodium amidotrizoate
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Apoptosis
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Inflammation/Immunology
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Sodium diatrizoate (Diatrizoic acid sodium salt) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Sodium diatrizoate induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
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- HY-B0926
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Diatrizoate; Amidotrizoic acid
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Apoptosis
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Inflammation/Immunology
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Diatrizoic acid (Diatrizoate) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Diatrizoic acid induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
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- HY-W799437
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Biochemical Assay Reagents
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Others
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Ioversol hydrolysate-1 is a hydrolyzate of Ioversol (HY-B1410), a non-ionic iodinated contrast agent (CM) used in CT scans or X-rays in animal experiments .
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- HY-116070
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4-Iodoantipyrine
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Fluorescent Dye
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Infection
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Iodoantipyrine (4-Iodoantipyrine) is an iodinated Antipyrine (HY-B0171) with potential antiviral activity. Antipyrine (Phenazone) is an antipyretic and analgesic that also serves as a molecular probe of hepatic oxidative metabolites .
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- HY-B1410
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MP-328
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Biochemical Assay Reagents
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Others
Cancer
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Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal .
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- HY-B0342
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Methylglucamine; Meglumin; Methylglucamin
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Biochemical Assay Reagents
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Cancer
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Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
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- HY-B0926R
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Diatrizoate (Standard); Amidotrizoic acid (Standard)
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Apoptosis
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Inflammation/Immunology
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Diatrizoic acid (Standard) is the analytical standard of Diatrizoic acid. This product is intended for research and analytical applications. Diatrizoic acid (Diatrizoate) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Diatrizoic acid induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
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- HY-B0926AR
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Apoptosis
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Inflammation/Immunology
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Sodium diatrizoate (Standard) is the analytical standard of Sodium diatrizoate. This product is intended for research and analytical applications. Sodium diatrizoate (Diatrizoic acid sodium salt) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Sodium diatrizoate induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
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- HY-B0342A
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Methylglucamine (Excipient); Meglumin (Excipient); Methylglucamin (Excipient)
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Biochemical Assay Reagents
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Cancer
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Meglumine (Methylglucamine) (Excipient) is an orally active amino sugar derived from sorbitol. Meglumine (Excipient) has anti-inflammatory and antitumor activity. Meglumine (Excipient) is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
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- HY-W097018
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Biochemical Assay Reagents
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Others
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Iomeprol intermediate-1 (compound 5) is an iodinated polysaccharide compound used in the synthesis of contrast agents. The amino group of Iomeprol intermediate-1 can be coupled to the carboxyl group of the D-glucuronide subunit of non-animal stable hyaluronic acid (NASHA), providing a water-soluble, radiopaque moiety .
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- HY-B1410R
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Biochemical Assay Reagents
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Others
Cancer
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Ioversol (Standard) is the analytical standard of Ioversol. This product is intended for research and analytical applications. Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal [4].
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- HY-B0342R
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Biochemical Assay Reagents
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Cancer
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Meglumine (Standard) is the analytical standard of Meglumine. This product is intended for research and analytical applications. Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
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- HY-B0684S
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Isotope-Labeled Compounds
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Others
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Iopamidol-d8 (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
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- HY-B0558
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p38 MAPK
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Neurological Disease
Endocrinology
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Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
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- HY-109513
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Ioxilan
1 Publications Verification
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Biochemical Assay Reagents
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Others
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Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs .
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- HY-W744953
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Isotope-Labeled Compounds
p38 MAPK
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Neurological Disease
Endocrinology
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Carbimazole-d3 is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
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- HY-B0558S
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Isotope-Labeled Compounds
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Neurological Disease
Endocrinology
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Carbimazole-d5 is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
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- HY-B0558R
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p38 MAPK
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Neurological Disease
Endocrinology
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Carbimazole (Standard) is the analytical standard of Carbimazole. This product is intended for research and analytical applications. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
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- HY-W097018R
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Biochemical Assay Reagents
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Others
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Iomeprol intermediate-1 (Standard) is the analytical standard of Iomeprol intermediate-1. This product is intended for research and analytical applications. Iomeprol intermediate-1 (compound 5) is an iodinated polysaccharide compound used in the synthesis of contrast agents. The amino group of Iomeprol intermediate-1 can be coupled to the carboxyl group of the D-glucuronide subunit of non-animal stable hyaluronic acid (NASHA), providing a water-soluble, radiopaque moiety .
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- HY-109513R
-
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Biochemical Assay Reagents
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Others
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Ioxilan (Standard) is the analytical standard of Ioxilan. This product is intended for research and analytical applications. Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs .
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- HY-P2434
-
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Somatostatin Receptor
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Neurological Disease
Metabolic Disease
Cancer
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AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
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- HY-116450
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Dopamine Receptor
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Neurological Disease
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TISCH is a potent and selective iodinated ligand with high affinity and selectivity for CNS D1 dopamine receptors. TISCH showed a Kd value of 0.205 nM in rat striatal tissue, indicating its effectiveness in biological activity. TISCH is able to easily cross the blood-brain barrier and show distribution in specific areas with D1 receptor density. TISCH is considered to be useful as a pharmacological tool for characterizing D1 dopamine receptors. When labeled with I-123, TISCH has the potential to be used as an in vivo imaging agent for CNS D1 dopamine receptors .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P10339
-
|
Peptides
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Inflammation/Immunology
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SMCY peptide inhibits the binding of iodinated standard peptide to HLA-B7 with an IC50 of 34 nM. As an epitope of the H-Y antigen, SMCY peptide can be presented by the HLA-B7 molecule and recognized by specific T cells, leading to transplant rejection .
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- HY-P2434
-
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Somatostatin Receptor
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Neurological Disease
Metabolic Disease
Cancer
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AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
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- HY-K3015
-
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Density Gradient Medium, also known as Iodixanol, is a low osmolality, non-ionic, iodinated density gradient medium.
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0684S
-
|
Iopamidol-d8 (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
|
-
-
- HY-W744953
-
|
Carbimazole-d3 is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
|
-
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- HY-B0558S
-
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Carbimazole-d5 is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
|
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Cat. No. |
Product Name |
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Classification |
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- HY-B0342A
-
Methylglucamine (Excipient); Meglumin (Excipient); Methylglucamin (Excipient)
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|
pH Modifiers
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Meglumine (Methylglucamine) (Excipient) is an orally active amino sugar derived from sorbitol. Meglumine (Excipient) has anti-inflammatory and antitumor activity. Meglumine (Excipient) is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
|
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