interleukin-13 receptor

By Targets:	Interleukin Related (2) mRNA (3)
By Research Areas:	Inflammation/Immunology (5) Neurological Disease (1)
Oligonucleotides:	mRNA (3)

Targets Recommended: Interleukin Related IRAK CX3CR1 Itk

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99025

Lebrikizumab 1 Publications Verification TNX-650	Interleukin Related	Neurological Disease Inflammation/Immunology
Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .

HY-P991259

MEDI-7836	Interleukin Related	Inflammation/Immunology
MEDI-7836 is a humanized monoclonal antibody inhibitor that targets the **interleukin-13 receptor**. MEDI-7836 is promising for research of inflammation-related diseases .

HY-174637

Human IL13RA2 mRNA	mRNA	Inflammation/Immunology
Human IL13RA2 mRNA encodes the human interleukin 13 receptor subunit alpha 2 (IL13RA2) protein, a subuint of the interleukin 13 receptor complex. IL13RA2 binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.

HY-174638

Human IL13RA1 mRNA	mRNA	Inflammation/Immunology
Human IL13RA1 mRNA encodes the human interleukin 13 receptor subunit alpha 1 (IL13RA1) protein, a subunit of the interleukin 13 receptor. IL13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. It has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

HY-174603

Human IL4R mRNA	mRNA	Inflammation/Immunology
Human IL4R mRNA encodes the human interleukin 4 receptor (IL4R) protein, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. IL4R also can bind interleukin 4 to promote differentiation of Th2 cells.

Cat. No.	Product Name	Target	Research Area

HY-P99025

Lebrikizumab 1 Publications Verification TNX-650	Interleukin Related	Neurological Disease Inflammation/Immunology
Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .

HY-P991259

MEDI-7836	Interleukin Related	Inflammation/Immunology
MEDI-7836 is a humanized monoclonal antibody inhibitor that targets the **interleukin-13 receptor**. MEDI-7836 is promising for research of inflammation-related diseases .

Species:	Human (4) Mouse (5) Rat (3) Cynomolgus (2) Canine (2)
Tag:	His (10) Tag Free (1) Avi (1) Fc (6)
Source:	HEK293 (16)

Cat. No.	Compare	Product Name	Species	Source

HY-P76990

	IL-13R alpha 2 Protein, Canine (HEK293, His) interleukin-13 receptor subunit alpha-1; IL-13RA1; NR4; CD213a1	Canine	HEK293
	The IL-13R α2 protein is a receptor for interleukin 13 (IL-13), a signaling molecule involved in immune responses. By binding to IL-13, the IL-13R α2 protein is thought to regulate IL-13-mediated immune responses and may serve as a therapeutic target for diseases associated with IL-13 dysregulation. IL-13R alpha 2 Protein, Canine (HEK293, His) is the recombinant canine-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P70196

	IL-13R alpha 1 Protein, Mouse (HEK293, Fc) rMuinterleukin-13 receptor subunit alpha-1/IL-13RA1, Fc; interleukin-13 receptor subunit alpha-1; IL-13RA1; interleukin-13-binding protein; Novel cytokine receptor 4; NR4; CD213a1	Mouse	HEK293
	The IL-13R α 1 protein binds to IL13 with low affinity and, when combined with IL4RA, forms a functional IL13 receptor. It also functions together with IL4RA as an alternative accessory protein for IL4 signaling. IL-13R alpha 1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72594

	IL-13R alpha 1 Protein, Human (HEK293, His) interleukin-13 receptor subunit alpha-1; IL-13R-alpha-1; IL-13RA1; CT19; CD213a1; IL13R	Human	HEK293
	The IL13RA1 protein is critical in immune signaling and binds with low affinity to IL13. It binds to IL4RA to form a functional IL13 receptor for cellular responses. IL-13R alpha 1 Protein, Human (HEK293, His) is the recombinant human-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76417

	IL-13R alpha 1 Protein, Rat (HEK293, Fc) interleukin-13 receptor subunit alpha-1; IL-13R-alpha-1; IL-13RA1; CT19; CD213a1; IL13R	Rat	HEK293
	Interleukin 13 receptor subunit alpha 1 is a subunit of the interleukin 13 receptor. Interleukin 13 receptor subunit alpha 1 has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL-13R alpha 1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77403

	IL-13R alpha 1 Protein, Cynomolgus (HEK293, His) interleukin-13 receptor subunit alpha-1; IL-13R-alpha-1; IL-13RA1; CT19; CD213a1; IL13R	Cynomolgus	HEK293
	The IL-13R α 1 protein binds to IL13 with low affinity and, when combined with IL4RA, forms a functional IL13 receptor. It also functions together with IL4RA as an alternative accessory protein for IL4 signaling. IL-13R alpha 1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75827

	IL-13R alpha 2 Protein, Human (HEK293, His) interleukin-13 receptor subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R	Human	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Human (HEK293, His) is the recombinant human-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P703689

	IL-13 R alpha 1/IL13RA1 Protein, Cynomolgus (HEK293, His) interleukin 13 receptor; alpha 1	Cynomolgus	HEK293
	IL-13 R alpha 1/IL13RA1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-13 R alpha 1/IL13RA1 protein, expressed by HEK293, with C-His tag.

HY-P72381

	IL-13R alpha 1 Protein, Mouse (Biotinylated, HEK293, Avi-His) interleukin-13 receptor subunit alpha-1; IL-13RA1; interleukin-13-binding protein; Novel cytokine receptor 4; NR4; CD213a1	Mouse	HEK293
	The IL-13R α 1 protein binds to IL13 with low affinity and, when combined with IL4RA, forms a functional IL13 receptor. It also functions together with IL4RA as an alternative accessory protein for IL4 signaling. IL-13R alpha 1 Protein, Mouse (Biotinylated, HEK293, Avi-His) is the recombinant mouse-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.

HY-P76989

	IL-13R alpha 2 Protein, Canine (HEK293, Fc) interleukin-13 receptor subunit alpha-1; IL-13RA1; NR4; CD213a1	Canine	HEK293
	The IL-13R α2 protein is a receptor for interleukin 13 (IL-13), a signaling molecule involved in immune responses. By binding to IL-13, the IL-13R α2 protein is thought to regulate IL-13-mediated immune responses and may serve as a therapeutic target for diseases associated with IL-13 dysregulation. IL-13R alpha 2 Protein, Canine (HEK293, Fc) is the recombinant canine-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75829

	IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) interleukin-13 receptor subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R	Human	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75830

	IL-13R alpha 2 Protein, Mouse (HEK293, Fc) interleukin-13 receptor subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R	Mouse	HEK293
	IL-13R alpha 2 Protein, acting as a monomer, displays a strong binding affinity for interleukin-13 (IL-13). IL-13R alpha 2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P75831

	IL-13R alpha 2 Protein, Mouse (HEK293, His-Fc) interleukin-13 receptor subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R	Mouse	HEK293
	IL-13R alpha 2 Protein, acting as a monomer, displays a strong binding affinity for interleukin-13 (IL-13). IL-13R alpha 2 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

HY-P75832

	IL-13R alpha 2 Protein, Mouse (HEK293, His) interleukin-13 receptor subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R	Mouse	HEK293
	The IL-13R alpha 2 protein is a high-affinity receptor for interleukin 13 (IL-13) that acts as a decoy receptor and does not induce signaling upon IL-13 binding. Mice lacking this protein exhibit increased serum immunoglobulins, interferon gamma production, and bone marrow macrophage progenitor cell frequencies. IL-13R alpha 2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75833

	IL-13R alpha 2 Protein, Rat (HEK293, Fc) interleukin-13 receptor subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R	Rat	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits strong affinity for binding to interleukin-13 (IL-13), thereby playing a crucial role in mediating the biological effects of IL-13 and regulating various cellular processes. IL-13R alpha 2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75834

	IL-13R alpha 2 Protein, Rat (HEK293, His) interleukin-13 receptor subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R	Rat	HEK293
	IL-13R alpha 2 Protein, functioning as a monomer, exhibits strong affinity for binding to interleukin-13 (IL-13), thereby playing a crucial role in mediating the biological effects of IL-13 and regulating various cellular processes. IL-13R alpha 2 Protein, Rat (HEK293, His) is the recombinant rat-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P7220

	IL-4R alpha/CD124 Protein, Human (HEK293) 1 Publications Verification rHuIL-4R; IL4R; IL-4RA; CD124	Human	HEK293
	IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. IL-4R alpha/CD124, Human (G24-H232) is produced in HEK293 cells with a full length of 209 amino acids.

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HY-P81879

	IL-13 Receptor alpha 1 Antibody (YA1624) IL13RA1; IL13R; IL13RA; interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1	WB	Human
	IL-13 Receptor alpha 1 Antibody (YA1624) is a non-conjugated IgG antibody, targeting IL-13 Receptor alpha 1, with a predicted molecular weight of 49 kDa (observed band size: 49 kDa). IL-13 Receptor alpha 1 Antibody (YA1624) can be used for WB experiment in human background.

HY-P81632

	IL-13 Receptor alpha 1 Antibody (YA1377) IL13RA1; IL13R; IL13RA; interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1	FC, ELISA	Human
	IL-13 Receptor alpha 1 Antibody (YA1377) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1377), targeting IL-13RA1. IL-13 Receptor alpha 1 Antibody (YA1377) can be used for FC, ELISA experiment in human background.

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Cat. No.	Product Name		Classification

HY-174637

Human IL13RA2 mRNA		mRNA
Human IL13RA2 mRNA encodes the human interleukin 13 receptor subunit alpha 2 (IL13RA2) protein, a subuint of the interleukin 13 receptor complex. IL13RA2 binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.

HY-174638

Human IL13RA1 mRNA		mRNA
Human IL13RA1 mRNA encodes the human interleukin 13 receptor subunit alpha 1 (IL13RA1) protein, a subunit of the interleukin 13 receptor. IL13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. It has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

HY-174603

Human IL4R mRNA		mRNA
Human IL4R mRNA encodes the human interleukin 4 receptor (IL4R) protein, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. IL4R also can bind interleukin 4 to promote differentiation of Th2 cells.

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