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Results for "

guanosine-3'

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Isotope-Labeled Compounds

2

Click Chemistry

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013330
    3′-Deoxyguanosine

    guanosine, 3'-deoxy-

    		 Nucleoside Antimetabolite/Analog Drug Derivative Metabolic Disease
    3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a derivative of Guanosine (HY-N0097). 3′-Deoxyguanosine interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. 3′-Deoxyguanosine exhibits moderate displacement activity for [ 3H]-guanosine in rat meninges. 3′-Deoxyguanosine is useful for studying the mechanism of guanosine receptors and purine metabolism [3].
    3′-Deoxyguanosine
  • HY-W654000
    Cyclic GMP-13C,15N2

    guanosine 3',5'-cyclic-13C,15N2 monophosphate

    		 Isotope-Labeled Compounds Endogenous Metabolite Infection Cardiovascular Disease Inflammation/Immunology
    Cyclic GMP- 13C, 15N2 is 13C and 15N labeled Cyclic GMP (HY-113469). Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses [3] .
    Cyclic GMP-13C,15N2
  • HY-117186
    Bis-propargyl-PEG6

    		PROTAC Linkers Metabolic Disease
    Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates . Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Bis-propargyl-PEG6
  • HY-133190
    Bis-propargyl-PEG7

    		PROTAC Linkers Metabolic Disease
    Bis-propargyl-PEG7 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG7 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates . Bis-propargyl-PEG7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Bis-propargyl-PEG7
  • HY-W800446
    LNA-Guanosine 3'-CE phosphoramidite

    Lna-g amidite

    		 Biochemical Assay Reagents Others
    LNA-Guanosine 3'-CE phosphoramidite (Lna-g amidite) is an essential building block to Locked Nucleic Acid (LNA) oligonucleotide synthesis, which includes a ribonucleoside linked by a methylene unit between the 2’-oxygen and 4’-carbon atoms, paralleling DNA polymer assembly.
    LNA-Guanosine 3'-CE phosphoramidite
  • HY-154628
    N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite

    		Nucleoside Antimetabolite/Analog Cancer
    N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite

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