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glucose synthesis

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23

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-128923
    SKF-34288 hydrochloride
    5+ Cited Publications

    3-Mercaptopicolinic acid hydrochloride; 3-MPA hydrochloride

    PEPCK Metabolic Disease
    SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (Ki: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides .
    SKF-34288 hydrochloride
  • HY-B0389A
    D-Glucose-13C6
    Maximum Cited Publications
    8 Publications Verification

    glucose-13C6; D-(+)-glucose-13C6; Dextrose-13C6

    Endogenous Metabolite Others Metabolic Disease
    D-Glucose- 13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- 13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .
    D-Glucose-13C6
  • HY-N2486
    Desoxyrhaponticin
    1 Publications Verification

    Fatty Acid Synthase (FASN) Apoptosis Cancer
    Desoxyrhaponticin is a kind of oral drug that inhibits effective fatty acid synthesis (FASN), and has a fatal effect on cancer cells. Desoxyrhaponticin has the ability to inhibit glucose uptake, improve oral glucose tolerance as a diabetic agent, and possess anti-diabetic effects.
    Desoxyrhaponticin
  • HY-128747R

    Reference Standards Endogenous Metabolite Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    α-D-Glucose-1-phosphate disodium (Standard) is the analytical standard of α-D-Glucose-1-phosphate disodium (HY-128747). This product is intended for research and analytical applications. α-D-Glucose-1-phosphate disodium is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element.
    α-D-Glucose-1-phosphate disodium (Standard)
  • HY-141131

    PROTAC Linkers Cancer
    Propargyl-PEG2-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Propargyl-PEG2-beta-D-glucose
  • HY-128747A

    Endogenous Metabolite Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    α-D-Glucose-1-phosphate disodium hydrate is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium hydrate can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element .
    α-D-Glucose-1-phosphate disodium hydrate
  • HY-128747

    Endogenous Metabolite Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    α-D-Glucose-1-phosphate disodium is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element .
    α-D-Glucose-1-phosphate disodium
  • HY-167016

    Liposome Others
    Cholesterol-undecanoate-glucose conjugate is a cholesterol conjugate used in the synthesis of intranasal liposomal vaccines. Cholesterol-undecanoate-glucose conjugate can be used in drug delivery studies .
    Cholesterol-undecanoate-glucose conjugate
  • HY-141132

    PROTAC Linkers Cancer
    Propargyl-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Propargyl-PEG4-beta-D-glucose
  • HY-141133

    PROTAC Linkers Cancer
    Propargyl-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Propargyl-PEG4-tetra-Ac-beta-D-glucose
  • HY-N9535

    Others Metabolic Disease
    tert-OMe-byakangelicin is a coumarin that can enhances the adrenaline-induced lipolytic effect and inhibits insulin-stimulated triglyceride synthesis from glucose in fat cells .
    tert-OMe-byakangelicin
  • HY-N2486R

    Reference Standards Fatty Acid Synthase (FASN) Apoptosis Cancer
    Desoxyrhaponticin (Standard) is the analytical standard of Desoxyrhaponticin. This product is intended for research and analytical applications. Desoxyrhaponticin is a kind of oral drug that inhibits effective fatty acid synthesis (FASN), and has a fatal effect on cancer cells. Desoxyrhaponticin has the ability to inhibit glucose uptake, improve oral glucose tolerance as a diabetic agent, and possess anti-diabetic effects .
    Desoxyrhaponticin (Standard)
  • HY-W400427

    Biochemical Assay Reagents Others
    α-D-Glucose-1-phosphate is an important intermediate in sugar metabolism, functioning as a glycosyl donor in glycosyl transfer reactions and participating in glycogen synthesis and degradation through the action of phosphorylases .
    α-D-Glucose-1-phosphate
  • HY-43747

    Acetobromo-α-D-glucose, contains 1% CaCO3 as stabilizer; Acetobromo-alpha-D-glucose, contains 1% CaCO3 as stabilizer

    Biochemical Assay Reagents Drug Intermediate Others
    α-Acetobromoglucose, contains 1% CaCO3 as stabilizer (Acetobromo-α-D-glucose, contains 1% CaCO3 as stabilizer) is a glycosyl donor that can be used for the synthesis of other active compounds .
    α-Acetobromoglucose, contains 1% CaCO3 as stabilizer
  • HY-W011082

    NOD-like Receptor (NLR) Cardiovascular Disease
    NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism .
    NLRP3-IN-2
  • HY-160247

    Drug-Linker Conjugates for ADC Others
    Boc-Lys-PEG8-N-bis(D-glucose) (compound 89-5) is a drug linker that can be used in the synthesis of antibody-drug conjugates (ADCs) extracted from patent WO2023280227A2 .
    Boc-Lys-PEG8-N-bis(D-glucose)
  • HY-N6006

    1,3,6-Tri-O-galloyl-β-D-glucose

    Others Others
    1,3,6-Tri-O-galloyl-beta-D-glucose is a non-covalent inhibitor of tyrosinase (TYR), which can block the rate-limiting step of melanin synthesis and inhibit melanin deposition. 1,3,6-Tri-O-galloyl-beta-D-glucose has antioxidant and anti-inflammatory activities and can be used as a natural active ingredient to develop anti-freckle and whitening skin care products .
    1,3,6-Tri-O-galloyl-beta-D-glucose
  • HY-I0144

    Drug Intermediate Others
    Thiazolidine is a five-membered heterocyclic compound containing sulfur and nitrogen heteroatoms. Thiazolidine is an important intermediate in organic synthesis. Thiazolidine derivatives possess diverse bioactivities, such as anti-tumor, antibacterial and insecticidal activities, and the capacity to reduce blood glucose levels .
    Thiazolidine
  • HY-140012

    PROTAC Linkers Cancer
    Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-beta-D-glucose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azido-PEG4-beta-D-glucose
  • HY-N10573
    UDP-rhamnose
    1 Publications Verification

    Endogenous Metabolite Others
    UDP-rhamnose is one of the substrates for pectin synthesis in cell wall. UDP-rhamnose can be identified in fungi. UDP-rhamnose is one of the most common sugar donors in plants. UDP-rhamnose synthesis requires recombinant enzymes. UDP-rhamnose can be synthesized from UDP-glucose through the consecutive three-step reaction catalyzed by a single structure enzyme in plants .
    UDP-rhamnose
  • HY-141127

    PROTAC Linkers Cancer
    Azido-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-tetra-Ac-beta-D-glucose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azido-PEG4-tetra-Ac-beta-D-glucose
  • HY-19997

    TATM

    Biochemical Assay Reagents Cancer
    Mannose triflate is a glucose analog. Mannose triflate is a precursor for 18F-FDG synthesis for PET applications. Mannose triflate binds to 18F via SN2 nucleophilic substitution reaction. Mannose triflate can be used for an imaging technique in detection of cancer .
    Mannose triflate
  • HY-N7676
    Marein
    2 Publications Verification

    AMPK HDAC Cardiovascular Disease Neurological Disease Metabolic Disease
    Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 μM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects .
    Marein
  • HY-W016203

    Sodium phenylpyruvate

    Endogenous Metabolite PDI Infection Metabolic Disease
    Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity .
    Phenylpyruvic acid sodium
  • HY-W015912

    2-Furyl methyl ketone

    Drug Intermediate Infection
    2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran also can be formed from glucose and glycine by Maillard reaction. 2-Acetylfuran can be used to synthesis Cefuroxime. 2-acetylfuran can be used in the synthesis of reagents with antiamoebic activity .
    2-Acetylfuran
  • HY-W357103

    Biochemical Assay Reagents Others
    3-O-(Phenylmethyl)-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    3-O-(Phenylmethyl)-D-glucose
  • HY-W415946

    Biochemical Assay Reagents Others
    2-Deoxy-D-glucose-tetraacetate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    2-Deoxy-D-glucose-tetraacetate
  • HY-W556338

    Biochemical Assay Reagents
    α-D-Glucose 1-phosphate (dipotassium) is a biochemical reagent used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
    α-D-Glucose 1-phosphate dipotassium
  • HY-W039863

    Biochemical Assay Reagents
    D-Glucose-6-phosphate (dipotassium hydrate) is a biochemical reagent used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
    D-Glucose-6-phosphate dipotassium hydrate
  • HY-W803822

    Biochemical Assay Reagents Others
    6-O-(Triphenylmethyl)-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    6-O-(Triphenylmethyl)-D-glucose
  • HY-N6701

    Arp2/3 Complex Cancer
    Dihydrocytochalasin B (H2CB) is a Cytokinesis inhibitor and changes the morphology of the cells, similar to that of cytochalasin B; does not inhibit glucose transport . Dihydrocytochalasin B (H2CB) disrupts the actin structure and inhibits the ability of growth factors to stimulate DNA synthesis, reversibly blocks initiation of DNA synthesis . Dihydrocytochalasin B (H2CB) inhibits active calcium transport and causes a Ca 2+increase in the mucosal scrapings .
    Dihydrocytochalasin B
  • HY-163771

    Pyruvate Carboxylase (PC) Metabolic Disease
    Pyruvate Carboxylase-IN-5 (compound 6m) is a pyruvate carboxylase inhibitor with high selectivity and permeability. Pyruvate carboxylase is a mitochondrial enzyme that catalyzes the carboxylation of pyruvate to oxaloacetate, a process that plays an important role in maintaining steady-state levels of Krebs cycle intermediates, which are precursors for the synthesis of biomacromolecules such as amino acids, fatty acids, and glucose .
    Pyruvate Carboxylase-IN-5
  • HY-W603111

    Biochemical Assay Reagents Others
    5-Thio-D-glucose-6-phosphate diammonium salt is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    5-Thio-D-glucose-6-phosphate diammonium salt
  • HY-113002A

    Biochemical Assay Reagents Others
    α-D-Glucose 1,6-bisphosphate (cyclohexanamine)is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    α-D-Glucose 1,6-bisphosphate cyclohexanamine
  • HY-W357096

    Biochemical Assay Reagents Others
    4-Deoxy-4-fluoro-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    4-Deoxy-4-fluoro-D-glucose
  • HY-W854349

    Biochemical Assay Reagents Others
    3-Chloro-3-deoxy-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    3-Chloro-3-deoxy-D-glucose
  • HY-W650834

    Biochemical Assay Reagents Others
    3-Acetamido-3-deoxy-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    3-Acetamido-3-deoxy-D-glucose
  • HY-W009078

    Biochemical Assay Reagents Others
    4-S-β-D-Glucopyranosyl-4-thio-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    4-S-β-D-Glucopyranosyl-4-thio-D-glucose
  • HY-W739643

    Biochemical Assay Reagents Others
    Methyl 4-deoxy-4-fluoro-α-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    Methyl 4-deoxy-4-fluoro-α-D-glucose
  • HY-W416179

    Acetobromolaminaribiose

    Biochemical Assay Reagents Others
    2,3,4,6-Tetra-O-acetyl-β-D-glucose (Acetobromolaminaribiose) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    2,3,4,6-Tetra-O-acetyl-β-D-glucose
  • HY-W011082R

    Reference Standards NOD-like Receptor (NLR) Cardiovascular Disease
    NLRP3-IN-2 (Standard) is the analytical standard of NLRP3-IN-2. This product is intended for research and analytical applications. NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism .
    NLRP3-IN-2 (Standard)
  • HY-N12486A

    Others Neurological Disease Metabolic Disease Cancer
    (3S,8R,9R)-Isofalcarintriol is a natural polyacetylene compound found in carrot root parts. (3S,8R,9R)-Isofalcarintriol is a potent longevity promoter that improves glucose metabolism and has anti-tumor activity. (3S,8R,9R)-Isofalcarintriol can affect cellular respiration, interact with the α subunit of mitochondrial ATP synthase, and promote mitochondrial biogenesis. (3S,8R,9R)-Isofalcarintriol can be used in the study of neurodegenerative diseases, metabolic diseases, and aging .
    (3S,8R,9R)-Isofalcarintriol
  • HY-E70070

    Bacterial Others
    Endo-β-N-acetylglucosaminidase (Endo A) is an Endo-β-N-acetylglucosaminidases (ENGases) from Arthrobacter protophormiae. Endo-β-N-acetylglucosaminidase (Endo A) can transfer a high-mannose type oligosaccharide to monosaccharides such as N-acetylglucosamine (GlcNAc) and glucose to form a new oligosaccharide. Endo-β-N-acetylglucosaminidase (Endo A) catalyzes glycopeptide synthesis by using Man3GlcNAc-oxazoline .
    Endo-β-N-acetylglucosaminidase (Endo A)
  • HY-124418
    SBI-477
    1 Publications Verification

    Fluorescent Dye Insulin Receptor LXR Arrestin Metabolic Disease
    SBI-477 is a chemical probe that stimulates insulin signaling by deactivating the transcription factor MondoA. SBI-477 can lead to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4). SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes .
    SBI-477
  • HY-108600

    DAPH-7

    PKC DNA/RNA Synthesis Cardiovascular Disease Metabolic Disease
    CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients .
    CGP-53353
  • HY-W706302

    Biochemical Assay Reagents Others
    D-Glucose,2-(acetylamino)-2-deoxy,3-acetate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    D-Glucose,2-(acetylamino)-2-deoxy,3-acetate
  • HY-128748

    Endogenous Metabolite Others
    DL-Glyceraldehyde is a bioactive substance involved in cellular energy metabolism and a key intermediate in sugar metabolism pathways (such as glycolysis and gluconeogenesis). During glycolysis, DL-Glyceraldehyde is converted by enzymes into other metabolites to provide energy for cells; during gluconeogenesis, DL-Glyceraldehyde participates in the synthesis of glucose as a precursor. In the field of medical research, DL-Glyceraldehyde can be used to study diseases related to sugar metabolism, such as diabetes, tumors, etc[1][2].
    DL-Glyceraldehyde
  • HY-W699037

    Biochemical Assay Reagents Others
    2-(Acetylamino)-2-deoxy-4-O-β-D-mannopyranosyl-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    2-(Acetylamino)-2-deoxy-4-O-β-D-mannopyranosyl-D-glucose
  • HY-W698571

    4-O-(3-O-Sulfo-β-D-galactopyranosyl)-D-glucose

    Biochemical Assay Reagents Others
    Lactose-3'-sulfate (4-O-(3-O-Sulfo-β-D-galactopyranosyl)-D-glucose) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    Lactose-3'-sulfate
  • HY-166967

    Biochemical Assay Reagents Others
    1,3,4,6-Tetra-O-acetyl-2-deoxy-2-trifluoracetamido-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    1,3,4,6-Tetra-O-acetyl-2-deoxy-2-trifluoracetamido-D-glucose

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