Search Result
        
        
            
                Results for "
gallate
" in MedChemExpress (MCE) Product Catalog:
            
         
        
        
            
                
            
            
            
            
            
            
            
            
                
            
            
            
                
                    4
Isotope-Labeled Compounds
 
            
            
            
            
                
            
         
        
            
            
                
                    
                    
                        
                            | Cat. No. | Product Name | Target | Research Areas | Chemical Structure | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-124082
- 
                                        
                                            
                                                | Lauryl gallate | Flavivirus
                                                    
                                                        Bacterial | Infection |  
                                                | Dodecyl gallate (Lauryl gallate) has been widely used as an antioxidant in food manufacturing, as well as in the pharmaceutical and cosmetic industries. Dodecyl gallate also acts antibacterial activity specifically against Gram-positive bacteria. Dodecyl gallate also is active against a highly relevant animal virus such as African swine fever virus (ASFV) . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-124082R
- 
                                        
                                            
                                                | Lauryl gallate (Standard) | Flavivirus
                                                    
                                                        Bacterial
                                                    
                                                        Reference Standards | Infection |  
                                                | Dodecyl gallate (Standard) is the analytical standard of Dodecyl gallate. This product is intended for research and analytical applications. Dodecyl gallate (Lauryl gallate) has been widely used as an antioxidant in food manufacturing, as well as in the pharmaceutical and cosmetic industries. Dodecyl gallate also is active against a highly relevant animal virus such as African swine fever virus (ASFV) . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0002R
- 
                                        
                                            
                                                | Epicatechin gallate(Standard); ECG(Standard); (-)-Epicatechin 3-O-gallate (Standard) | Reference Standards
                                                    
                                                        COX
                                                    
                                                        Autophagy
                                                    
                                                        Virus Protease | Cancer |  
                                                | (-)-Epicatechin gallate (Standard) is the analytical standard of (-)-Epicatechin gallate. This product is intended for research and analytical applications. (-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 7.5 μM. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0002
- 
                                        
                                            
                                                | Epicatechin gallate;  ECG; (-)-Epicatechin 3-O-gallate | COX
                                                    
                                                        Autophagy
                                                    
                                                        Virus Protease | Cancer |  
                                                | (-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 7.5 μM. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0356
- 
                                        
                                            
                                                | (-)-Catechin 3-gallate;  (-)-Catechin 3-O-gallate | COX | Cancer |  
                                                | (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N8129
- 
                                        
                                            
                                                |  | Others | Others |  
                                                | Rhaponticin 6′′-O-gallate is a stilbene glucoside gallate that can be found in rhizome of Rheum undulatum L. Rhaponticin 6′′-O-gallate inhibits nitric oxide production in lipopolysaccharide-activated macrophages . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0522R
- 
                                        
                                            
                                                | (-)-Gallocatechol gallate (Standard) | Reference Standards
                                                    
                                                        Others | Cancer |  
                                                | (-)-Gallocatechin gallate (Standard) is the analytical standard of (-)-Gallocatechin gallate. This product is intended for research and analytical applications. (-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0356R
- 
                                        
                                            
                                                | (-)-Catechin 3-gallate (Standard); (-)-Catechin 3-O-gallate (Standard) | Reference Standards
                                                    
                                                        COX | Cancer |  
                                                | (-)-Catechin gallate (Standard) is the analytical standard of (-)-Catechin gallate. This product is intended for research and analytical applications. (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N16453
- 
                                        
                                            
                                                |  | Proteasome | Neurological Disease
                                                    
                                                        Cancer |  
                                                | (+)-Catechin 3-gallate is an orally active polyphenolic compound that acts as a non-selective proteasome inhibitor. (+)-Catechin 3-gallate exerts antitumor effects by inducing apoptosis and suppressing inflammatory cytokines. (+)-Catechin 3-gallate is promising for research of cancers (e.g., breast, prostate) and neurodegenerative diseases (e.g., Alzheimer’s) . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0244R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Others | Cancer |  
                                                | Theaflavin-3'-gallate (Standard) is the analytical standard of Theaflavin-3'-gallate. This product is intended for research and analytical applications. Theaflavin-3'-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3'-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3'-gallate reacts directly with reduced glutathione (GSH) in a time-and concentration-dependent manner . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N8082
- 
                                        
                                            
                                                |  | HSV | Infection |  
                                                | Stearyl gallate is an alkyl gallate with a long alkyl chain (carbon number of 18). Stearyl gallate has an antioxidant activity, and a weak antiviral activity against HSV-1  . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0524R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0245
- 
                                        
                                            
                                                |  | Apoptosis
                                                    
                                                        MDM-2/p53
                                                    
                                                        ATM/ATR
                                                    
                                                        Checkpoint Kinase (Chk) | Cancer |  
                                                | Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner. Theaflavin-3-gallate induces apoptosis and G1 cell cycle arrest in ovarian cancer A2780/CP70 cells through p53-dependent pathways. Theaflavin-3-gallate induces DNA damage through ATM/Chk/p53 pathway  . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0524
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0245R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Apoptosis
                                                    
                                                        MDM-2/p53
                                                    
                                                        ATM/ATR
                                                    
                                                        Checkpoint Kinase (Chk) | Cancer |  
                                                | Theaflavin-3-gallate (Standard) is the analytical standard of Theaflavin-3-gallate. This product is intended for research and analytical applications. Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner. Theaflavin-3-gallate induces apoptosis and G1 cell cycle arrest in ovarian cancer A2780/CP70 cells through p53-dependent pathways. Theaflavin-3-gallate induces DNA damage through ATM/Chk/p53 pathway  . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0525R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Bacterial | Metabolic Disease
                                                    
                                                        Cancer |  
                                                | Ethyl gallate (Standard) is the analytical standard of Ethyl gallate. This product is intended for research and analytical applications. Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0522
- 
                                        
                                            
                                                | (-)-Gallocatechol gallate | COMT | Cancer |  
                                                | (-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-13653R
- 
                                        
                                            
                                                | EGCG(Standard); Epigallocatechol gallate (Standard) | Reference Standards
                                                    
                                                        Endogenous Metabolite
                                                    
                                                        Apoptosis | Inflammation/Immunology
                                                    
                                                        Cancer |  
                                                | (-)-Epigallocatechin Gallate (Standard) is the analytical standard of (-)-Epigallocatechin Gallate. This product is intended for research and analytical applications. (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma    . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-13653
- 
                                        
                                            
                                                | EGCG;  Epigallocatechol gallate | Endogenous Metabolite
                                                    
                                                        Apoptosis | Inflammation/Immunology
                                                    
                                                        Cancer |  
                                                | (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma    . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0244
- 
                                        
                                            
                                                |  | Xanthine Oxidase
                                                    
                                                        Apoptosis
                                                    
                                                        Necroptosis | Cancer |  
                                                | Theaflavin-3'-gallate is a monomer of theaflavins found in black tea, which has anti-UVB damage activity and inhibits cell apoptosis and necroptosis. Theaflavin-3'-gallate acts as a pro-oxidant and induces oxidative stress in cancer cells, inhibiting xanthine oxidase (OX), with an IC50 of 7.6 μM   . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N8125
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-13653S
- 
                                        
                                            
                                                |  | Oxidative Phosphorylation
                                                    
                                                        Autophagy
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                        HIV
                                                    
                                                        Ferroptosis
                                                    
                                                        Mitochondrial Metabolism
                                                    
                                                        Endogenous Metabolite | Cancer |  
                                                | (+/-)-Epigallocatechin Gallate- 13C3 is the  13C-labeled (-)-Epigallocatechin Gallate. (-)-Epigallocatechin Gallate is a tea flavonoid with potent antioxidant, antiinflammatory, and anticarcinogenic properties. (-)-Epigallocatechin Gallate is reported to inhibit EGFR signaling and thereby exert anticancer effects . (-)-Epigallocatechin Gallate (EGCG) is a glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) inhibitor. Epigallocatechin-3-gallate induces oxidative phosphorylation (OXPHOS) by activating cytochrome c oxidase. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0356S
- 
                                        
                                            
                                                |  | Isotope-Labeled Compounds
                                                    
                                                        COX | Cancer |  
                                                | (+/-)-Catechin Gallate- 13C3 is the  13C-labeled (-)-Catechin gallate. (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2011R
- 
                                        
                                            
                                                | n-Octyl gallate (Standard); Stabilizer GA 8 (Standard) | VSV
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        HSV
                                                    
                                                        Influenza Virus
                                                    
                                                        Reactive Oxygen Species (ROS) | Infection |  
                                                | Octyl gallate (Standard) is the analytical standard of Octyl gallate. This product is intended for research and analytical applications. Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity  . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2011
- 
                                        
                                            
                                                | n-Octyl gallate;  Stabilizer GA 8 | VSV
                                                    
                                                        Bacterial
                                                    
                                                        HSV
                                                    
                                                        Influenza Virus
                                                    
                                                        Reactive Oxygen Species (ROS) | Infection |  
                                                | Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity  . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0525
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-13653S1
- 
                                        
                                            
                                                | EGCG-d4;  Epigallocatechol gallate-d4 | Isotope-Labeled Compounds
                                                    
                                                        Apoptosis | Inflammation/Immunology
                                                    
                                                        Cancer |  
                                                | (-)-Epigallocatechin Gallate-d4 (EGCG-d4) is the deuterium labeled (-)-Epigallocatechin Gallate (HY-13653). (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma    . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N7727
- 
                                        
                                            
                                                |  | Others | Others |  
                                                | Gallocatechin gallate is a Flavonoids product that can be isolated from the herbs of Celastrus orbiculatus . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N8589
- 
                                        
                                            
                                                |  | Others | Others |  
                                                | (-)-Epiafzelechin-3-O-gallate is a natural product that can be isolated from the water extract of Pu-erh tea. (-)-Epiafzelechin-3-O-gallate shows antioxidant activity . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2010
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N13559
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2010R
- 
                                        
                                            
                                                | Gallincin (Standard); NSC 363001 (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        HIV
                                                    
                                                        Reactive Oxygen Species (ROS) | Infection
                                                    
                                                        Cardiovascular Disease
                                                    
                                                        Cancer |  
                                                | Methyl gallate (Standard) is the analytical standard of Methyl gallate. This product is intended for research and analytical applications. Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N16483
- 
                                        
                                            
                                                |  | Apoptosis
                                                    
                                                        Caspase
                                                    
                                                        Bcl-2 Family
                                                    
                                                        PARP
                                                    
                                                        Androgen Receptor | Cancer |  
                                                | Procyanidin B2-3'-O-gallate is a mono-gallate ester that can be isolated from grape seed extract. Procyanidin B2-3'-O-gallate has anti-cancer efficacy and reduces the viability of prostate carcinoma LNCaP cells. Furthermore, Procyanidin B2-3'-O-gallate induces apoptosis, and causes caspases-9 and -3 and PARP cleavage, and down-regulates Bcl-2, Bcl-Xl and androgen receptor levels . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N4298
- 
                                        
                                            
                                                |  | MMP | Metabolic Disease
                                                    
                                                        Inflammation/Immunology |  
                                                | Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-170017S
- 
                                        
                                            
                                                | EGCG-d3/d4;  Epigallocatechol gallate-d3/d4 | Isotope-Labeled Compounds
                                                    
                                                        Apoptosis | Inflammation/Immunology
                                                    
                                                        Cancer |  
                                                | (-)-Epigallocatechin Gallate-d3/d4 (EGCG-d3/d4) is the deuterium labeled (-)-Epigallocatechin Gallate (HY-13653). (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma    . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N9790
- 
                                        
                                            
                                                |  | Notch | Others |  
                                                | Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-135652
- 
                                        
                                            
                                                | Hexyl 3,4,5-trihydroxybenzoate | Bacterial
                                                    
                                                        Parasite | Infection |  
                                                | Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR . Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N9777
- 
                                        
                                            
                                                |  | Others | Metabolic Disease |  
                                                | Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC50 of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N15663
- 
                                        
                                            
                                                | EGCG4′′Me | Drug Derivative | Inflammation/Immunology |  
                                                | (-)-Epigallocatechin-3-O-(4-O-methyl)gallate is an orally active catechin derivative found in Taiwanese oolong tea. (-)-Epigallocatechin-3-O-(4-O-methyl)gallate can inhibit histamine release and exhibits anti-inflammation and anti-allergic effect. (-)-Epigallocatechin-3-O-(4-O-methyl)gallate can be used for the researches of immunology and inflammation, such as type I allergic . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2228
- 
                                        
                                            
                                                | (-)-EGCG-3''-O-ME | Others | Inflammation/Immunology
                                                    
                                                        Cancer |  
                                                | (-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product that can be isolated from the tea leaf, with strong antioxidative activity.  (-)-Epigallocatechin-3-(3''-O-methyl) gallate has a strong cytotoxic activity for rat cancer cells . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N6263
- 
                                        
                                            
                                                | AcEGCG; Peracetylated (-)-epigallocatechin-3-gallate | Bacterial
                                                    
                                                        PI3K
                                                    
                                                        Akt
                                                    
                                                        NF-κB | Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                        Cancer |  
                                                | EGCG Octaacetate (AcEGCG) is a proagent of Green tea epigallocatechin-3-gallate (EGCG). EGCG Octaacetate decreases the proinflammatory mediator levels by down-regulating of PI3K/Akt/NFκB phosphorylation and p65 acetylation. EGCG octaacetate is the potential antibacterial compound for gram-positive bacteria (GPB) and gram-negative bacteria (GNB). EGCG Octaacetate exhibits antioxidant, anti-angiogenesis, anti-inflammatory and antitumor activities   . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-120145
- 
                                        
                                            
                                                | 
                                                        
                                                            MST-312
                                                            
                                                        
                                                        
                                                            
                                                                
                                                                
                                                                
                                                                    2 Publications Verification Telomerase Inhibitor IX | Telomerase | Cancer |  
                                                | MST-312 is a telomerase inhibitor. MST-312 is a chemically modified derivative of green tea epigallocatechin gallate (EGCG). MST-312 can be used for the research of cancer, such as multiple myeloma (MM) . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-127139
- 
                                        
                                            
                                                | Eicosapentaenoic acid Chloride;  EPA Chloride | Endogenous Metabolite | Metabolic Disease |  
                                                | Eicosapentaenoyl chloride is a derivative of eicosapentaenoic acid. It has been used in the synthesis of fatty acid conjugates to enhance lipophilicity and cell permeability of bioactive compounds such as (–)-epigallocatechin gallate and salicylic acid. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-150526
- 
                                        
                                            
                                                |  | Endogenous Metabolite
                                                    
                                                        Apoptosis | Inflammation/Immunology
                                                    
                                                        Cancer |  
                                                | EGCG-4″-sulfate is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate sulfate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. EGCG-4″-sulfate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma    . |  
 
- 
                                        
                                        
                                              
 
 
            
            
            
            
            
            
            
            
            
            
            
            
            
            
            
                
                    
                        
                            | Cat. No. | Product Name | Category | Target | Chemical Structure | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-N0002R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0002
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0356
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0524R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0245
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N8129
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0522R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0356R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N16453
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0244R
- 
                                        
                                            
                                                |  | Flavonoids
                                                            
                                                        
                                                            
                                                            
                                                                Flavanols
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Phenols
                                                            
                                                        
                                                            
                                                            
                                                                Polyphenols
                                                            
                                                        
                                                            
                                                            
                                                                Camellia sinensis (L.) O. Ktze.
                                                            
                                                        
                                                            
                                                            
                                                                Plants
                                                            
                                                        
                                                            
                                                            
                                                                Theaceae 
                                                        
                                                     | Reference Standards
                                                    
                                                        Others |  
                                                | Theaflavin-3'-gallate (Standard) is the analytical standard of Theaflavin-3'-gallate. This product is intended for research and analytical applications. Theaflavin-3'-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3'-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3'-gallate reacts directly with reduced glutathione (GSH) in a time-and concentration-dependent manner . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0245R
- 
                                        
                                            
                                                |  | Flavonoids
                                                            
                                                        
                                                            
                                                            
                                                                Flavanols
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Phenols
                                                            
                                                        
                                                            
                                                            
                                                                Polyphenols
                                                            
                                                        
                                                            
                                                            
                                                                Camellia sinensis (L.) O. Ktze.
                                                            
                                                        
                                                            
                                                            
                                                                Plants
                                                            
                                                        
                                                            
                                                            
                                                                Theaceae 
                                                        
                                                     | Reference Standards
                                                    
                                                        Apoptosis
                                                    
                                                        MDM-2/p53
                                                    
                                                        ATM/ATR
                                                    
                                                        Checkpoint Kinase (Chk) |  
                                                | Theaflavin-3-gallate (Standard) is the analytical standard of Theaflavin-3-gallate. This product is intended for research and analytical applications. Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner. Theaflavin-3-gallate induces apoptosis and G1 cell cycle arrest in ovarian cancer A2780/CP70 cells through p53-dependent pathways. Theaflavin-3-gallate induces DNA damage through ATM/Chk/p53 pathway  . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0525R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0522
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-13653R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-13653
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0244
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N8125
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2011R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2011
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0525
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N7727
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N8589
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2010
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N13559
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2010R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N16483
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N4298
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N9790
- 
                                        
                                            
                                                |  | Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Vitis vinifera cv. Zalema
                                                            
                                                        
                                                            
                                                            
                                                                Phenols
                                                            
                                                        
                                                            
                                                            
                                                                Polyphenols
                                                            
                                                        
                                                            
                                                            
                                                                Plants
                                                            
                                                        
                                                            
                                                            
                                                                Vitaceae 
                                                        
                                                     | Notch |  
                                                | Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N9777
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N15663
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N2228
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-150526
- 
                                        
                                    
- 
                                        
                                        
                                              
 
 
            
            
            
            
            
                
                    
                        
                            | Cat. No. | Product Name | Chemical Structure | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-13653S1
- 
                                        
                                            
                                                |  |  
                                                | (-)-Epigallocatechin Gallate-d4 (EGCG-d4) is the deuterium labeled (-)-Epigallocatechin Gallate (HY-13653). (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma    . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-13653S
- 
                                        
                                            
                                                |  |  
                                                | (+/-)-Epigallocatechin Gallate- 13C3 is the  13C-labeled (-)-Epigallocatechin Gallate. (-)-Epigallocatechin Gallate is a tea flavonoid with potent antioxidant, antiinflammatory, and anticarcinogenic properties. (-)-Epigallocatechin Gallate is reported to inhibit EGFR signaling and thereby exert anticancer effects . (-)-Epigallocatechin Gallate (EGCG) is a glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) inhibitor. Epigallocatechin-3-gallate induces oxidative phosphorylation (OXPHOS) by activating cytochrome c oxidase. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N0356S
- 
                                        
                                            
                                                |  |  
                                                | (+/-)-Catechin Gallate- 13C3 is the  13C-labeled (-)-Catechin gallate. (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes. |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-170017S
- 
                                        
                                            
                                                |  |  
                                                | (-)-Epigallocatechin Gallate-d3/d4 (EGCG-d3/d4) is the deuterium labeled (-)-Epigallocatechin Gallate (HY-13653). (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma    . |  
 
- 
                                        
                                        
                                              
 
 
            
            
            
            
            
                
                
                    
                        
                            
                                | Cat. No. | Product Name |  | Classification | 
                        
                        
                            
                            
                        - 
                            
                                - HY-N0524
- 
                                    
                                        
                                            |  |  | Others |  
                                            | Propyl gallate is a common food antioxidant. Propyl gallate can inhibit the production of acrolein, glyoxal and methylglyoxal. Propyl gallate exhibits anti-inflammatory, antitumor and cardioprotective activities    . |  
 
 
 
                
         
        
        
        
        
        
        
            
            Your information is safe with us.  * Required Fields. 
             
        
        
            
            
                
                
                Inquiry Information
                
                    - Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent: