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folic acid

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16637
    Folic acid
    10+ Cited Publications

    Vitamin B9; Vitamin M

    DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .
    Folic acid
  • HY-16637R

    DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Folic acid (Standard) is the analytical standard of Folic acid. This product is intended for research and analytical applications. Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .
    Folic acid (Standard)
  • HY-400648

    Drug Metabolite Cancer
    Folic acid methyl ester is a methyl ester metabolite of folic acid that can be used in the study of neuropsychiatric conditions, such as depression [1] .
    Folic acid methyl ester
  • HY-16637D
    Folic acid disodium
    10+ Cited Publications

    Vitamin B9 disodium; Vitamin M disodium

    Endogenous Metabolite DNA/RNA Synthesis Others Neurological Disease Cancer
    Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 5 g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .
    Folic acid disodium
  • HY-16637S1

    Vitamin B9-d4; Vitamin M-d4

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Cancer
    Folic acid-d4 is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
    Folic acid-d4
  • HY-16637S3

    Vitamin B9-13C5; Vitamin M-13C5

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Cancer
    Folic acid- 13C5 is the 13C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
    Folic acid-13C5
  • HY-16637A

    Vitamin B9 sodium; Vitamin M sodium

    DNA/RNA Synthesis Endogenous Metabolite Neurological Disease
    Folic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .
    Folic acid sodium
  • HY-16637S5

    Vitamin B9-13C6; Vitamin M-13C6

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Cancer
    Folic acid-13C6 is a deuterated labeled Folic acid . Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .
    Folic acid-13C6
  • HY-16637S

    Vitamin B9-d2; Vitamin M-d2

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Cancer
    Folic acid-d2 (Vitamin B9-d2) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
    Folic acid-d2
  • HY-16637S4

    Vitamin B9-13C5,15N; Vitamin M-13C5,15N

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Others
    Folic acid- 15N, 13C5 is the 13C5 and 15N labeled Folic acid (HY-16637) .
    Folic acid-13C5,15N
  • HY-132070

    folic acid-PEG5-Mal

    PROTAC Linkers Cancer
    FA-PEG5-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    FA-PEG5-Mal
  • HY-17383
    Levomefolate calcium
    2 Publications Verification

    Antifolate Neurological Disease
    Levomefolate calcium is an orally active, BBB-penatrable and active form of folic acid. Levomefolate calcium can be used as a food supplement for folic acid and in the research of neural tube defect diseases .
    Levomefolate calcium
  • HY-14781A

    L-5-MTHF magnesium

    Endogenous Metabolite Reactive Oxygen Species DNA/RNA Synthesis Infection Cancer
    Levomefolic acid magnesium is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .
    Levomefolic acid magnesium
  • HY-14781
    Levomefolic acid
    2 Publications Verification

    L-5-MTHF

    Endogenous Metabolite Reactive Oxygen Species DNA/RNA Synthesis Infection Cancer
    Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .
    Levomefolic acid
  • HY-14518

    4-Aminofolic acid; APGA

    Antifolate Inflammation/Immunology Cancer
    Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia .
    Aminopterin
  • HY-14518R

    Antifolate Inflammation/Immunology Cancer
    Aminopterin (Standard) is the analytical standard of Aminopterin. This product is intended for research and analytical applications. Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia .
    Aminopterin (Standard)
  • HY-B0946

    Antibiotic Bacterial Infection
    Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .
    Sulfamonomethoxine
  • HY-B0946S

    Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Sulfamonomethoxine-d4 is a deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .
    Sulfamonomethoxine-d4
  • HY-121151

    (±)-Amethopterin; (±)-CL14377; (±)-WR19039

    Antifolate Others
    (±)-Methotrexate ((±)-Amethopterin) is a racemate of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of Folic acid into Tetrahydrofolate, and inhibiting DNA synthesis .
    (±)-Methotrexate
  • HY-B0946R

    Antibiotic Bacterial Infection
    Sulfamonomethoxine (Standard) is the analytical standard of Sulfamonomethoxine (HY-B0946). This product is intended for research and analytical applications. Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .
    Sulfamonomethoxine (Standard)
  • HY-14518A

    4-Aminofolic acid sodium; APGA sodium

    Antifolate Cancer
    Aminopterin sodium (4-Aminofolic acid sodium) is an anti-tumor drug with immunosuppressive activity. Aminopterin sodium blocks the metabolism of folic acid by inhibiting the activity of dihydrofolate reductase, thereby affecting nucleic acid synthesis. Aminopterin sodium is mainly used to inhibit acute lymphoblastic leukemia and certain other types of cancer. Aminopterin sodium is also used clinically as an immunosuppressant to suppress autoimmune diseases .
    Aminopterin sodium
  • HY-103396
    Trimetrexate glucuronate
    2 Publications Verification

    CI-898 glucuronate

    Antifolate Bacterial Infection Cancer
    Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia .
    Trimetrexate glucuronate
  • HY-W037819

    Drug Derivative Metabolic Disease
    6-Methylpterin is a derivative of the essential B vitamin Folic acid (HY-16637). 6-Methylpterin generates singlet oxygen and hydrogen peroxide when exposed to Photoirradiation. 6-Methylpterin can be used for the detection of pterins in urine .
    6-Methylpterin
  • HY-113046
    5-Methyltetrahydrofolic acid
    5+ Cited Publications

    5-Methyl THF; 5-MTHF

    Endogenous Metabolite Cardiovascular Disease Metabolic Disease
    5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases .
    5-Methyltetrahydrofolic acid
  • HY-13615

    EC-17

    Fluorescent Dye Others Cancer
    Folate-FITC (EC-17) is a folic acid derivative that binds to fluorescein isothiocyanate (FITC) to give it fluorescent labeling properties. Folate-fitc is used to induce the formation of pseudo-immunological synapses between anti-FITC CAR T cells and target cells expressing Folate receptors (FRα or FRβ). Folate-FITC can be used to develop controlled CAR-T cell therapies for research in non-small cell lung cancer (NSCLC) .
    Folate-FITC
  • HY-103396R

    CI-898 glucuronate (Standard)

    Antifolate Bacterial Infection Cancer
    Trimetrexate (glucuronate) (Standard) is the analytical standard of Trimetrexate (glucuronate). This product is intended for research and analytical applications. Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia[1][2].
    Trimetrexate glucuronate (Standard)
  • HY-16637S2

    (Rac)-Vitamin B9-13C5,15N; (Rac)-Vitamin M-13C5,15N

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Cancer
    (Rac)-Folic acid- 13C5, 15N is the 13C-labeled and 15N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
    (Rac)-Folic acid-13C5,15N
  • HY-17383A

    Antifolate Neurological Disease
    Levomefolate disodium is an orally active, BBB-penatrable and active form of folic acid. Levomefolate disodium can be used as a food supplement for folic acid and in the research of neural tube defect diseases .
    Levomefolate disodium
  • HY-123098

    Antifolate Bacterial DNA/RNA Synthesis Cancer
    Tetrahydromethotrexate is a more potent folate antagonist than Methotrexate (HY-14519) in studies against certain bacteria (Streptococcus faecalis, Pediococcus erevisiae) and in animal models. Tetrahydromethotrexate is used in the research of cancer and autoimmune diseases .
    Tetrahydromethotrexate
  • HY-122378

    Pteroyl diglutamic acid; Folate monoglutamate

    Antifolate Cancer
    Diopterin is a folic acid analog that is used in leukemia research .
    Diopterin
  • HY-129398

    Endogenous Metabolite Metabolic Disease
    Formiminoglutamic acid, an endogenous metabolite, could be an index of folic-acid deficiency .
    Formiminoglutamic acid
  • HY-121652

    Drug Metabolite Others
    Mefox is a degradation product of folic acid (HY-16637) .
    Mefox
  • HY-14781S2

    L-5-MTHF-13C5

    DNA/RNA Synthesis Endogenous Metabolite Reactive Oxygen Species Cancer
    Levomefolic acid- 13C5 is the 13C labeled Levomefolic acid[1]. Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[2][3].
    Levomefolic acid-13C5
  • HY-14781S1

    L-5-MTHF-13C,d3

    Isotope-Labeled Compounds DNA/RNA Synthesis Reactive Oxygen Species Endogenous Metabolite Others
    Levomefolic acid- 13C,d3 is the deuterium labeled Levomefolic acid (HY-14781) . Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .
    Levomefolic acid-13C,d3
  • HY-117757

    9-Me-PGA; 9-Methyl PGA

    Endogenous Metabolite Others
    Ninopterin (9-Me-PGA; 9-Methyl PGA) is a folic acid analog .
    Ninopterin
  • HY-17383R

    Antifolate Neurological Disease
    Levomefolate (calcium) (Standard) is the analytical standard of Levomefolate (calcium). This product is intended for research and analytical applications. Levomefolate (calcium) is an orally active, BBB-penatrable and active form of folic acid. Levomefolate (calcium) can be used as a food supplement for folic acid and in the research of neural tube defect diseases .
    Levomefolate (calcium) (Standard)
  • HY-14781S3

    L-5-MTHF-d3

    Isotope-Labeled Compounds DNA/RNA Synthesis Reactive Oxygen Species Endogenous Metabolite Infection Cancer
    Levomefolic acid-d3 (L-5-MTHF-d3) is deuterium labeled Levomefolic acid. Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .
    Levomefolic acid-d3
  • HY-113046R

    Endogenous Metabolite Cardiovascular Disease Metabolic Disease
    Alisol C 23-acetate (Standard) is the analytical standard of Alisol C 23-acetate. This product is intended for research and analytical applications. Alisol C 23-acetate is a natural product extracted from Alisma orientale, which can significantly reduce delayed-type hypersensitivity reactions.
    5-Methyltetrahydrofolic acid (Standard)
  • HY-108251
    Methotrexate metabolite
    1 Publications Verification

    DAMPA

    Antifolate Drug Metabolite Dihydrofolate reductase (DHFR) Parasite Infection Inflammation/Immunology
    Methotrexate metabolite (DAMPA) is an active metabolite of Methotrexate. Methotrexate is a Folic acid (HY-16637) antagonist, widely used as an immunosuppressant. Methotrexate metabolite is an antimalarial agent that inhibits parasite growth under physiological folic acid conditions, with IC50 values of 446 nM and 812 nM against folic acid-sensitive strains and highly resistant strains, respectively. Methotrexate metabolite exhibits pharmacokinetic characteristics of rapid clearance and extensive metabolism, with a mean clearance rate of 1.9 l/kg/h and a mean terminal half-life of 51 minutes. Methotrexate metabolite is promising for research in the field of inflammation .
    Methotrexate metabolite
  • HY-D2844A

    Fluorescent Dye Neurological Disease
    FITC-PEG-FA (MW 1000) is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG-FA (MW 1000) can be used for fluorescent labeling and imaging .
    FITC-PEG-FA (MW 1000)
  • HY-D2844C

    Fluorescent Dye Neurological Disease
    FITC-PEG-FA (MW 3400) is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG-FA (MW 3400) can be used for fluorescent labeling and imaging .
    FITC-PEG-FA (MW 3400)
  • HY-D2844E

    Fluorescent Dye Neurological Disease
    FITC-PEG-FA (MW 10000) is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG-FA (MW 10000) can be used for fluorescent labeling and imaging .
    FITC-PEG-FA (MW 10000)
  • HY-D2844B

    Fluorescent Dye Neurological Disease
    FITC-PEG-FA (MW 2000) is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG-FA (MW 2000) can be used for fluorescent labeling and imaging .
    FITC-PEG-FA (MW 2000)
  • HY-D2844

    Fluorescent Dye Neurological Disease
    FITC-PEG-FA (MW 400) is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG-FA (MW 400) can be used for fluorescent labeling and imaging .
    FITC-PEG-FA (MW 400)
  • HY-D2844D

    Fluorescent Dye Neurological Disease
    FITC-PEG-FA (MW 5000) is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG-FA (MW 5000) can be used for fluorescent labeling and imaging .
    FITC-PEG-FA (MW 5000)
  • HY-W097570

    Bacterial Antibiotic Infection
    Sulfamonomethoxine sodium is a long acting sulfonamide?antibacterial?agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate .
    Sulfamonomethoxine sodium
  • HY-B0337B

    Sulphadimethoxine 1000 µg/mL in methanol

    Antibiotic Infection
    Sulfadimethoxine 1000 μg/mL in methanol (Sulphadimethoxine 1000 μg/mL in methanol) is a sulfonamide antibiotic that inhibits the enzyme dihydropteroate synthase, thereby blocking dihydrofolic acid synthesis and disrupting folic acid production in prokaryotic organisms. Its antimicrobial activity extends to both Gram-positive and Gram-negative bacteria, as well as Chlamydia. Resistance to this compound may arise through alterations in dihydropteroate synthase or the activation of alternative pathways for folic acid synthesis.
    Sulfadimethoxine 1000 µg/mL in methanol
  • HY-13664
    Folinic acid calcium
    5+ Cited Publications

    Leucovorin calcium; Calcium folinate

    Antifolate Endogenous Metabolite Cancer
    Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
    Folinic acid calcium
  • HY-17556
    Folinic acid
    5+ Cited Publications

    leucovorin

    Antifolate Endogenous Metabolite Cancer
    Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity .
    Folinic acid
  • HY-B0080

    Leucovorin calcium salt pentahydrate

    Antifolate Endogenous Metabolite Cancer
    Folinic acid calcium salt pentahydrate (Leucovorin calcium salt pentahydrate) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
    Folinic acid calcium salt pentahydrate

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