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Results for "

flavonoid derivative

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Apoptosis (5) Bacterial (6) Calcium Channel (1) Caspase (1) ClpP (2) COX (3) Endogenous Metabolite (2) ERK (1) Fungal (2) Glycosidase (1) HBV (1) Interleukin Related (2) JNK (3) NF-κB (1) p38 MAPK (2) PARP (1) Reactive Oxygen Species (3)
By Research Areas:	Cancer (7) Cardiovascular Disease (3) Infection (7) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Drug Derivative

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2857

Alpinumisoflavone	Others	Others
Alpinumisoflavone (compound 2) is a flavonoid derivative isolated from the stem bark of Erythrina lysistemon Hutch .

HY-N8920

Syringetin	Others	Metabolic Disease
Syringetin, a flavonoid derivative, is associated with increased BMP-2 production. Syringetin stimulates osteoblast differentiation at various stages, from maturation to terminally differentiated osteoblasts .

HY-N11464

Kuwanon O	Others	Others
Kuwanon O is a flavonoid derivative with a fused dihydrochalcone partial moiety, that can be isolated from the root bark of Morus lhou (set.) Koidz .

HY-W510941

Hesperetin dihydrochalcone	Others	Others
Hesperetin dihydrochalcone is a flavonoid derivative with a flavoring activity .

HY-126422

cis-Tiliroside	Others	Cancer
cis-Tiliroside, a kaempferol derivative, is a flavonoid glycoside. cis-Tiliroside exhibits better cytotoxic activity than trans-Tiliroside in A549 cell line .

HY-N7321A

(R)-Eucomol	Bacterial	Infection Cancer
(R)-Eucomol, a flavonoid derivative, displays marginal antibacterial activity. (R)-Eucomol shows cytotoxic activity against KB and P-388 cells .

HY-N12669

Curcumin monoglucoside	Bacterial Reactive Oxygen Species Apoptosis JNK Caspase	Neurological Disease
Curcumin monoglucoside is a flavonoid derivative possessing antioxidant, anti-apoptotic, neuroprotective effects, and antibacterial activity. Curcumin monoglucoside can be used in research on Parkinson's disease.

HY-N0172S

Caffeic acid-13C3 3,4-Dihydroxycinnamic acid-¹³C₃	Bacterial Fungal	Infection
Caffeic acid- ¹³C₃ is an ¹³C labeled caffeic acid. Caffeic acid is a phytonutrient belonging to the flavonoids. Caffeic acid and its derivatives, are potential antimicrobial agents, chronic infection induced by microbes such as bacteria, fungi, and viruses .

HY-158053

Antifungal agent 94	Fungal	Infection
Antifungal agent 94 (Compound 49) is a Flavonoid derivative, which exhibits antifungal activity with EC₅₀ of 0.28 μM and a half-maximal effective concentration of 0.46 μg/mL against Rhizoctonia solani .

HY-N12309

2′-O-Methylphloretin	Others	Others
2′-O-Methylphloretin (compound 3) is a flavonoid derivative. 2′-O-Methylphloretin can be isolated from the leaves of Melodorum siamensis. 2′-O-Methylphloretin inhibits the tumor cell line replication .

HY-148560B

cis-ccc_R08	HBV	Infection
cis-ccc_R08 (compound 1) is a flavonoid derivative that can be used in the study of hepatitis B virus (HBV) infection. cis-ccc_R08 is a cccDNA (covalently closed circular DNA) inhibitor .

HY-N6605

Kaempferol 3-O-β-D-galactopyranoside 1 Publications Verification Trifolin	Apoptosis	Cardiovascular Disease Cancer
Kaempferol 3-O-β-D-galactopyranoside (Trifolin) is an orally active flavonoid derivative that can be found in the aerial parts of Consolida oliverana. Kaempferol 3-O-β-D-galactopyranoside exhibits antitumor and cardioprotective effects .

HY-156332

TNKS-2-IN-2	PARP	Cancer
TNKS-2-IN-2 is a potent and selective inhibitor of TNKS2 with an IC₅₀ of 22 nM .

HY-N11499

Myricetin 3-O-α-L-arabinopyranoside	Bacterial	Infection Inflammation/Immunology
Myricetin 3-O-α-L-arabinopyranoside is a quercetin derivative and plant flavonoid with antioxidant, antibacterial and antiurease effects. Myricetin 3-O-α-L-arabinopyranoside inhibits A2E photooxidation-induced RPE cell death. Myricetin 3-O-α-L-arabinopyranoside is protective against retinal degeneration and protects against blue light (BL)-induced damage in RPE cells and mouse models .

HY-N12138

Flaccidoside III	Glycosidase	Metabolic Disease
Flaccidoside III is a flavonoid and triterpenoid isolated from the aerial parts of N. sativa (Ranunculaceae). Flaccidoside III inhibits α-Glucosidase (IC₅₀: 256.7 μM) and has potential antioxidant and antidiabetic activities .

HY-106449

Recoflavone DA-6034 free acid	NF-κB COX Apoptosis ERK Calcium Channel	Inflammation/Immunology Cancer
Recoflavone (DA-6034 (free acid)), a synthetic derivative of the flavonoid Eupatilin (HY-N0783), is orally active. Recoflavone can inhibit the NF-κB pathway and induce [Ca( ²⁺)]_i increase in epithelial cells. Recoflavone exhibits activities such as anti-inflammation, anti-tumor effects, protection of gastric and intestinal mucosa, and promotion of secretion in the ocular surface and salivary glands. Recoflavone can be used for the research of diseases such as dry eye, gastric injury, and intestinal injury .

HY-N1181

Tamarixetin 1 Publications Verification 4'-O-Methyl Quercetin	Endogenous Metabolite ClpP Bacterial Apoptosis Akt Interleukin Related COX JNK p38 MAPK Reactive Oxygen Species	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC₅₀ of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .

HY-N1181R

Tamarixetin (Standard)	Endogenous Metabolite ClpP Bacterial Apoptosis Akt Interleukin Related COX JNK p38 MAPK Reactive Oxygen Species	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC₅₀ of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .

HY-N8618

Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol	Others	Others
Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol was identified as one of the phenolic compounds isolated from Canadian maple syrup (MS-BuOH). It exhibited antioxidant properties along with other phenolic compounds and coumarins isolated from the syrup. These compounds showed varying degrees of antioxidant activity, with phenolic derivatives and coumarins showing superior activity, more so than lignans and flavonoids. This study marks the first time that 16 of the 23 phenolic compounds, including Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol, have been identified in maple syrup .

Cat. No.	Product Name

HY-L021M

Natural Product and Natural Product-Like Compound Library	0 compounds
From the discovery of traditional Chinese medicine to modern antibiotics, natural products have played an important role in the drug development process. A review of all FDA-approved drugs shows that natural products and natural product-like compounds account for more than one-third of all approved drugs. Nearly half of that came from mammals, a quarter from microbes, and a quarter from plants. Over time, the proportion of microbial natural products and natural product derivatives in approved drugs has increased. Natural products have natural advantages in drug development and can be used as lead compounds in drug discovery for drug identification and mechanism research. MCE provides a unique collection of 0 natural compounds and natural product-like compounds that contain saccharides and glycosides, phenylpropanoids, quinones, flavonoids, terpenoids and glycosides, steroids, alkaloid, phenols, acids and aldehydes. Natural product and natural product-like compounds library is a useful tool for drug discovery that can be used for high-throughput screening (HTS) and high-content screening (HCS).

Natural Product and Natural Product-Like Compound Library

0 compounds

From the discovery of traditional Chinese medicine to modern antibiotics, natural products have played an important role in the drug development process. A review of all FDA-approved drugs shows that natural products and natural product-like compounds account for more than one-third of all approved drugs. Nearly half of that came from mammals, a quarter from microbes, and a quarter from plants. Over time, the proportion of microbial natural products and natural product derivatives in approved drugs has increased. Natural products have natural advantages in drug development and can be used as lead compounds in drug discovery for drug identification and mechanism research.

MCE provides a unique collection of 0 natural compounds and natural product-like compounds that contain saccharides and glycosides, phenylpropanoids, quinones, flavonoids, terpenoids and glycosides, steroids, alkaloid, phenols, acids and aldehydes. Natural product and natural product-like compounds library is a useful tool for drug discovery that can be used for high-throughput screening (HTS) and high-content screening (HCS).

Cat. No.	Product Name	Category	Target	Chemical Structure