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Results for "

collagen-binding integrin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Integrin (2) Biochemical Assay Reagents (1) Endogenous Metabolite (1)
By Research Areas:	Cardiovascular Disease (2) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Targets Recommended: Collagen Integrin Emopamil Binding Protein Penicillin-binding protein (PBP) Cdc42-binding kinase ATP-binding cassette (ABC) transporters Oxysterol-binding Protein-related Protein (ORP) FKBP FABP Transthyretin (TTR) Ligands for Target Protein for PROTAC YB-1 SDCBP GHR P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107588

TC-I 15 1 Publications Verification	Integrin	Cardiovascular Disease
TC-I 15 (TC-I-15) is a type of allosteric collagen-binding integrin α2β1 inhibitor, and it also inhibits α1β1 and α11β1. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition. TC-I 15 prevents the formation of a pre-metastatic microenvironment by inhibiting the uptake of cancer-associated fibroblast (CAF) extracellular vesicles (EVs) by lung fibroblasts, which reduces the metastasis of salivary gland adenocystic carcinoma (SACC) to the lungs in mouse models, .

HY-P2975

Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) Mouse laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)	Endogenous Metabolite Biochemical Assay Reagents	Neurological Disease
Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth.

HY-177331

BTT-3034	Integrin	Cardiovascular Disease
BTT-3034, a sulfonamide derivative, is an α2β1 integrin inhibitor. BTT-3034 inhibits cell adhesion to rat tail collagen I with an EC₅₀ of 160 nM and a corresponding E_maxof 86%. BTT-3034 inhibits collagen binding by an α2 variant carrying the conformationally activating E318W mutation .

Cat. No.	Product Name	Type

HY-P2975

Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) Mouse laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)	Native Proteins
Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth.

Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)

Mouse laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)

Native Proteins

Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth.

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