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Results for "

cardiac troponin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (2) Calcium Channel (3) MAP3K (2) Potassium Channel (1)
By Research Areas:	Cardiovascular Disease (9) Inflammation/Immunology (1) Metabolic Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-147292

Nelutroctiv CK-136	Calcium Channel	Cardiovascular Disease
Nelutroctiv (CK-136) is an orally active and selective **cardiac troponin** activator. Nelutroctiv activates cardiac sarcomeres by enhancing the sensitivity of troponin to calcium ions and promoting the interaction between actin and myosin. Nelutroctiv enhances cardiac contractility. Nelutroctiv can be used in the researches for cardiovascular diseases with impaired cardiac contractile function .

HY-106844A

(+)-EMD 57033	Others	Cardiovascular Disease
(+)-EMD 57033 is a cardiac troponin C (cTnC) activator, is a dominant Ca ²⁺ sensitizer. (+)-EMD 57033 binds the cardiac/slow skeletal troponin C isoform and exerts myocardial contractile promotion function .

HY-162345

CK-963	Calcium Channel	Cardiovascular Disease
CK-963 is an activator for **cardiac troponin (cTnC) with K_i** of 11.5 μM. CK-963 exhibits activity in enhancing cardiac contractility in Sprague-Dawley rats .

HY-119608

GSK854	MAP3K	Cardiovascular Disease
GSK854 is a potent Inhibitor of Troponin I-Interacting Kinase (TNNI3K). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure .

HY-131948

3-Chlorodiphenylamine	Potassium Channel	Cardiovascular Disease
3-Chlorodiphenylamine is a high affinity Ca ²⁺ sensitizer of cardiac muscle. 3-Chlorodiphenylamine is based on diphenylamine and binds to the isolated N-domain of cardiac troponin C (cTnC) (K_d=6 µM). 3-Chlorodiphenylamine is an excellent starting scaffold for the development of more potent Ca ²⁺-sensitizing compounds due to its small size, and can be used for systolic heart failure research .

HY-117658

GSK-114	MAP3K	Cardiovascular Disease
GSK-114 is a highly selective, orally active TNNI3K inhibitor (IC₅₀= 25 nM). GSK-114 shows a 40-fold selectivity for TNNI3K over B-Raf kinase (IC₅₀= 1 μM). Cardiac troponin I-interacting kinase (TNNI3K or CARK) is a member of the tyrosine-like kinase family that is selectively expressed in heart tissue .

HY-NP196

*Human cardiac* troponin (mixture)** cTn	Biochemical Assay Reagents	Metabolic Disease
Human cardiac troponin (mixture) (cTn) is a regulatory protein for muscle tissue contraction, located on the thin filaments of contractile proteins, and plays an important regulatory role in muscle contraction and relaxation .

HY-130272

Anti-MI/R injury agent 1	Others	Cardiovascular Disease
Anti-MI/R injury agent 1 (compound 18), a Panaxatriol derivative, is an orally active, potent anti-myocardial ischemia/reperfusion (anti-MI/R) injury agent. Anti-MI/R injury agent 1 enhances oxygen-glucose deprivation and reperfusion (OGD/R)-induced cardiomyocyte injury cell viability. Anti-MI/R injury agent 1 can markedly reduce myocardial infarction size, decrease circulating cardiac troponin I (cTnI) leakage, and alleviate cardiac tissue damage in the rats .

HY-176041

Troponin modulator 1	Calcium Channel	Cardiovascular Disease
Troponin modulator 1 (compound 7) modulates the mutant cardiac muscle thin filament function. Troponin modulator 1 enhances Ca ²⁺ sensitivity by phosphorylation with an EC₅₀ of 67 μM .

HY-137749A

MANT-dADP trisodium 2'-Deoxy-3'-MANT-ADP trisodium	Biochemical Assay Reagents	Others
MANT-dADP (trisodium) (2'-Deoxy-3'-MANT-ADP (trisodium)) is a fluorescent nucleotide derivative, with an emission maximum of 453 nm upon excitation at 350 nm. MANT-dADP (trisodium) can decrease inositol phoshate formation in CHO-K1 cells that express human purinergic P2Y₁₂ receptor. MANT-dADP (trisodium) can be studied in research on the interaction between cardiac troponin I and myofibrils .

Cat. No.	Product Name	Type

HY-NP196

*Human cardiac* troponin (mixture)** cTn	Native Proteins
Human cardiac troponin (mixture) (cTn) is a regulatory protein for muscle tissue contraction, located on the thin filaments of contractile proteins, and plays an important regulatory role in muscle contraction and relaxation .

Cat. No.	Product Name	Target	Research Area

HY-P11206

*Murine cardiac* troponin I peptide** Murine cardiac TnI peptide	Peptides	Cardiovascular Disease Inflammation/Immunology
Murine cardiac troponin I peptide (Murine cardiac TnI peptide) is a murine cardiac troponin I (cTnI) peptide. Murine cardiac troponin I peptide can induce significant myocardial inflammation followed by fibrosis and heart failure with increased mortality in mice model. Murine cardiac troponin I peptide can be used for heart failure research .

Species:	Mouse (2)
Tag:	His (2) SUMO (1) Flag (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P71469

	Cardiac troponin I/Tnni3 Protein, Mouse (His-SUMO) Tnni3; troponin I; cardiac muscle; cardiac troponin I	Mouse	E. coli
	Cardiac troponin I, also known as Tnni3, plays a key role as an inhibitory subunit in the troponin complex, a key regulator of calcium sensitivity in actomyosin ATPase activity in striated muscle.Tnni3 interacts with TRIM63, emphasizing its involvement in complex cellular processes.Cardiac troponin I/Tnni3 Protein, Mouse (His-SUMO) is the recombinant mouse-derived Cardiac troponin I/Tnni3 protein, expressed by E.coli , with N-SUMO, N-6*His labeled tag.

HY-P703646

	Tnnt2 Protein, Mouse (His, Flag) troponin T, cardiac muscle; TnTc; cardiac muscle troponin T (cTnT)	Mouse	E. coli
	Tnnt2 Protein, Mouse (His, Flag) is the recombinant mouse-derived Tnnt2, expressed by E. coli , with C-6*His, C-Flag labeled tag. ,

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HY-P86432

	Cardiac Troponin T Antibody (YA6124) TNNT2; troponin T, cardiac muscle; TnTc; cardiac muscle troponin T; cTnT	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	Cardiac Troponin T Antibody (YA6124) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cardiac Troponin T.

HY-P81144

	Cardiac Troponin I Antibody (YA3484) troponin I type 3 (cardiac); cardiac troponin I; troponin I, cardiac muscle; Cardiomyopathy, familial hypertrophic, 7, included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; Tn1; Tni; TNN I3; TNNC 1; TNNC-1; TNNC1; TNNI3; troponin I cardiac; troponin I cardiac muscle; troponin I cardiac muscle isoform; troponin I type 3 cardiac; troponin I, cardiac 3; troponinI; troponin I; TNNI3_HUMAN.	WB, IHC-P, ICC/IF, IP	Human
	Cardiac Troponin I Antibody (YA3484) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cardiac Troponin I.

HY-P85398

	Cardiac Troponin I Antibody (YA5090) TNNI3; TNNC1; troponin I; cardiac muscle; cardiac troponin I	WB, IHC-P, ICC/IF, ELISA	Human
	Cardiac Troponin I Antibody (YA5090) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cardiac Troponin I.

HY-P86427

	Cardiac Troponin I Antibody (YA6119) TNNI3; TNNC1; troponin I; cardiac muscle; cardiac troponin I	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Cardiac Troponin I Antibody (YA6119) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cardiac Troponin I.

HY-P82974

	Cardiac Troponin T Antibody (YA2719) TNNT2; cardiac muscle troponin T; troponin T; cardiac muscle; troponin T type 2 (cardiac); cardiac muscle troponin T antibody Cardiomyopathy dilated 1D (autosomal dominant) antibody; Cardiomyopathy hypertrophic 2 antibody; CMD1D antibody; CMH2 antibody; CMPD2 antibody; cTnT antibody; LVNC6 antibody; MGC3889 antibody; OTTHUMP00000033864 antibody; RCM3 antibody; TNNT 2 antibody; TNNT2 antibody; TNNT2_HUMAN antibody; TnTc antibody; troponin T cardiac muscle antibody; troponin T2 cardiac antibody	WB, IHC-P	Human, Mouse, Rat
	Cardiac Troponin T Antibody (YA2719) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cardiac Troponin T.

HY-P82380

	Cardiac Troponin I/TNNC1 Antibody (YA2125) tnnc1a; TNC; Tnnc1; TNNI3; troponin C	WB, IHC-P	Human, Mouse, Rat
	Cardiac Troponin I/TNNC1 Antibody (YA2125) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cardiac Troponin I/TNNC1.

HY-P84334

	Cardiac Troponin T Antibody (YA4031) CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6	WB, IHC-P, FC, ELISA	Human, Mouse
	Cardiac Troponin T Antibody (YA4031) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cardiac Troponin T.

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