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ascites

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (55) Endocrinology (1) Infection (31) Inflammation/Immunology (6) Metabolic Disease (2) Neurological Disease (8)

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MDM-2/p53 (2)

Mitosis (1)

MMP (2)

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Nucleoside Antimetabolite/Analog (1)

Phosphodiesterase (PDE) (1)

Reference Standards (3)

Topoisomerase (4)

Vasopressin Receptor (1)

VEGFR (2)

By Research Areas:

Cancer (55)

Endocrinology (1)

Infection (31)

Inflammation/Immunology (6)

Metabolic Disease (2)

Neurological Disease (8)

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Products

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5535

Invopressin OCE-205	Vasopressin Receptor	Inflammation/Immunology
Invopressin (Compound 42) is a vasopressin V1A receptor partial agonist (EC₅₀: 1.0 nM). Invopressin can be used for research of cirrhosis, including bacterial peritonitis, HRS2 and refractory ascites .

HY-D0085

DiSC3(5) 5+ Cited Publications	Fluorescent Dye	Others
DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

HY-125120

Kansuiphorin C	Bacterial	Others
Kansuiphorin C ameliorates malignant ascites by modulating gut microbiota and related metabolic functions .

HY-136110

2-Keto-D-galactose D-Galactosone	DNA/RNA Synthesis	Cancer
2-Keto-D-galactose (D-Galactosone) inhibits DNA synthesis, and inhibits proliferation of in vitro grown Ehrlich ascites tumor cells .

HY-N8317

Rubicordifolin	Others	Cancer
Rubicordifolin is a natural product that can be isolated from Rubia cordifolia. Rubicordifolin inhibits the growth of sarcoma ascites in mice. Rubicordifolin has significant cytotoxic activity both in vitro and in vivo .

HY-129762

Yoshi-864 NSC-102627	DNA/RNA Synthesis	Cancer
Yoshi-864 (NSC-102627) is an alkylsulfonate DNA crosslinker with anticancer activity. Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Yoshi-864 also has a persistent reduction in ability to synthesize DNA in tumor cells from mice bearing the Ehrlich tumor .

HY-128514

Minimycin Oxazinomycin	Antibiotic Bacterial	Infection Cancer
Minimycin (Oxazinomycin) is a nucleoside antibiotic with a broad-spectrum antibacterial activity. Minimycin has inhibitory effect on mouse Ehrlich ascites* carcinoma, ascites* type and solid type sarcoma-180 .

HY-N14726

Primocarcin	Antibiotic Bacterial	Infection Cancer
Primocarcin is an antibiotic that inhibits Ehrlich ascites cancer .

HY-N14009

Carzinophillin A	Others	Cancer
Carzinophillin A has an inhibitory effect on ascites carcinoma and Yoshida sarcoma .

HY-W775009

Imidazole salicylate	COX	Inflammation/Immunology
Imidazole salicylate is a nonsteroidal anti-inflammatory drug that can be used to study cirrhosis and ascites .

HY-N14258

Kerriamycin A	Bacterial	Infection Cancer
Kerriamycin A has anti-Gram-positive bacterial effect and can inhibits Ai's ascites cancer .

HY-118327

Maleuric acid N-carbamylmaleamic acid	DNA/RNA Synthesis Mitosis	Cancer
Maleuric acid has cytotoxicity on Ehrlich ascites tumor cells by preventing the entry of preprophase cells into mitosis.

HY-N14259

Kerriamycin C	Bacterial	Infection Cancer
Kerriamycin C has anti-Gram-positive bacterial effect and can inhibits Ai's ascites cancer .

HY-N14550

Cyclogregatin	Bacterial Fungal	Infection Cancer
Cyclogregatin has anti-bacterial and fungal activity. Cyclogregatin inhibits airy ascites carcinoma with a MIC of 10 μg/mL .

HY-169684

Vaccarin C	Fungal	Infection Cancer
Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC₅₀ values of 3.35 and 5.72 μM, respectively .

HY-N14301

Aquayamycin	Antibiotic Bacterial	Infection Cancer
Aquayamycin is an angucycline antibiotic. Aquayamycin is active against Gram-positive bacteria, Ehrlich ascites carcinoma, and Yoshida rat sarcoma cells .

HY-N14165

Endusamycin	DNA/RNA Synthesis	Cancer
Endusamycin can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect .

HY-127014

Julimycin B2	Bacterial	Infection Cancer
Julimycin B2 has anti-Gram-positive bacteria and anti-virus activity and it has effects on ehrman ascites carcinoma in mice .

HY-N14753

Juglomycin A	Bacterial	Infection Cancer
Juglomycin A has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg .

HY-N14659

Pilatin	Bacterial Fungal	Infection
Pilatin has inhibitory effects on bacteria and fungi, and has strong inhibitory effects on the incorporation of thymidin and ureidin into DNA and RNA in Ehrlich carcinoma ascites cells .

HY-N14754

Juglomycin B	Bacterial	Infection Cancer
Juglomycin B has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg .

HY-119589

Altersolanol B Dactylarin	Antibiotic	Others
Altersolanol B (Dactylarin), a compound isolated from fungi, is structurally related to antibiotics and has been shown to induce ATP catabolism in Ehrlich ascites tumor cells.

HY-N15050

Cervicarcin	Antibiotic Bacterial	Infection Cancer
Cervicarcin is an antitumor antibiotic with a strong inhibitory effect on sarcoma 180 and sarcoma NF, but has a weak effect on sarcoma 37, Ehrman's ascites cancer and Friend leukemia .

HY-129469

Saframycin S	Antibiotic	Infection
Saframycin S is an antibiotic with a racemomycin group that exhibits inhibitory activity against Ehrlich ascites tumors. The LD₅₀ of Saframycin S in ddY mice is 3.2 mg/kg (i.p.) .

HY-N14785

Deflectin 1a	Antibiotic Bacterial	Infection Cancer
Deflectin 1a is an antibiotic with the activity of lysing bacteria, lysing red blood cells and inhibiting Ehrlich ascites cancer cells, and its activity can be offset by adding serum or serum albumin .

HY-W775009R

Imidazole salicylate (Standard)	COX Reference Standards	Inflammation/Immunology
Imidazole salicylate (Standard) is the analytical standard of Imidazole salicylate. This product is intended for research and analytical applications. Imidazole salicylate is a nonsteroidal anti-inflammatory drug that can be used to study cirrhosis and ascites .

HY-P99262

Imalumab BAX69; Anti-Human MIF Recombinant Antibody	Macrophage migration inhibitory factor (MIF)	Cancer
Imalumab (BAX69) is a recombinant, human IgG1 monoclonal antibody that targets macrophage inhibitory factor (MIF). Imalumab can be used for the research of ovarian carcinoma, recurrent malignant ascites and cancer .

HY-157901

2,3-Dihydroxybutanoic acid 2,3-Dihydroxybutyric acid	Drug Derivative	Cancer
2,3-Dihydroxybutanoic acid is an anticancer agent that can be extracted from the leaves of Corydalis. 2,3-Dihydroxybutanoic acid has anticancer activity both in vitro and in vivo and is lethal to Ehrlich ascites tumor cells .

HY-130803

5-Methyl-5,6-dihydrouridine	Nucleoside Antimetabolite/Analog	Cancer
5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. 5-Methyl-5,6-dihydrouridine can be used for nucleic acid modification .

HY-120285

M-0002 hydrochloride RWJ-351647 hydrochloride; SPD-556 hydrochloride	Endogenous Metabolite	Endocrinology
M-0002 hydrochloride (RWJ-351647 hydrochloride) is a biologically active compound that acts as an antagonist of the vasopressin V2 receptor. M-0002 hydrochloride is potentially useful for inhibiting ascites. M-0002 hydrochloride shows excellent properties that are favorable for clinical development .

HY-P991526

M701	CD3	Cancer
M701 is a humanized bispecific CD3/EpCAM T-cell engager antibody. M701 effectively kill high EpCAM expressing cancer cells. M701 can be used for the study of malignant ascites and gastric cancer .

HY-N14028

Coriolin A	Bacterial	Infection Cancer
Coriolin A has anti-Gram-positive bacteria, negative bacteria (weak), yeast and vaginal trichomoniasis activities. Coriolin A of 5 μg/mL can inhibit the growth of yoshida sarcoma 61.6%. Coriolin A has no inhibitory effect on Ehrlich ascites carcinoma in animals .

HY-N14941

Phleomycin G	Antibiotic Bacterial	Infection Cancer
Phleomycin G is a heteropeptide antibiotic. Phleomycin G has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin G extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin G inhibits airy entity carcinoma in mice .

HY-N14029

Coriolin B	Bacterial	Infection Cancer
Coriolin B has anti-Gram-positive bacteria, negative bacteria (weak), yeast and vaginal trichomoniasis activities. Coriolin B of 5 μg/mL can inhibit the growth of yoshida sarcoma 61.6%. Coriolin B has no inhibitory effect on Ehrlich ascites carcinoma in animals .

HY-N14030

Coriolin C	Bacterial	Infection Cancer
Coriolin C has anti-Gram-positive bacteria, negative bacteria (weak), yeast and vaginal trichomoniasis activities. Coriolin C of 5 μg/mL can inhibit the growth of yoshida sarcoma 61.6%. Coriolin C has no inhibitory effect on Ehrlich ascites carcinoma in animals .

HY-N14887

Phleomycin E	Antibiotic Bacterial	Infection Cancer
Phleomycin E is a heteropeptide antibiotic. Phleomycin E has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin E extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin E inhibits airy entity carcinoma in mice with an IC₅₀ of 0.31 μg/mL .

HY-119789

Albofungin	Antibiotic Bacterial	Infection
Albofungin (Antibiotic P-42-1) is isolated from the culture filtrate of Actinomyces tumemacerans strain INMI.P-42. Albofungin shows highly active on a wide variety of gram-positive bacteria and fungi. Albofungin shows cytotoxic to HeLa cell cultures and exhibited antitumor activity on EHRLICH ascites tumor in mice.

HY-19606

Cytogenin Antibiotic MI 43-37F11	Interleukin Related NO Synthase	Metabolic Disease Inflammation/Immunology Cancer
Cytogenin (Antibiotic MI 43-37F11) is an orally active antineoplastic antibiotic. Cytogenin regulates the inflammatory cytokine, reduces the levels of iNOS, NO and IL-6 in mouse macrophages, and exhibits antidiabetic efficacy in mice. Cytogenin inhibits growth of Ehrlich ascites tumor in mouse model .

HY-121123

Adamantanine 2-Aminoadamantane-2-carboxylic acid	Aminopeptidase	Cancer
Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (K_i is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC₅₀ of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S_0.5 of 10.5 .

HY-126835

A924	Amino Acid Derivatives	Cancer
A 924 is an amino acid derivative-based, orally active antitumor agent. A 924 is effective in inhibiting ascites tumors in rat models by intraperitoneal injection or oral administration. The LD₅₀ of A 924 in mice is >1.5 g/kg and >4.5 g/kg by intraperitoneal injection or oral administration, respectively. A 924 does not cause teratogenicity or adverse reactions in normal or pregnant mice .

HY-114535

Jaceidin	EGFR	Cancer
Jaceidin is a promising lead molecule for potent VEGFR inhibitor with excellent membrane permeability and oral bioavailability. Jaceidin exhibits anti-tumor activities .

HY-150015

4,5'-Dimethylangelicin-NHS	DNA/RNA Synthesis	Cancer
4,5'-Dimethylangelicin-NHS is a modified 4,5'-Dimethylangelicin containing an NHS. 4,5'-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5'-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5'-Dimethylangelicin has potential as a photochemotherapy agent .

HY-161853

TX-2552	Phosphodiesterase (PDE)	Others
TX-2552 is an orally active tyrosine DNA phosphodiesterase 1 (TDP1) inhibitor with an IC₅₀ value of 0.62 μM. TX-2552 can enhance the clastogenic activity of Topotecan (HY-13768) in mouse bone marrow cells, as well as the anti-tumor effect of Topotecan (HY-13768) in Krebs-2 ascites tumor mice .

HY-N14853

Ossamycin	Bacterial Fungal	Infection
Ossamycin is a macrolide antibiotic. Ossamycin has anti-fungal effect, and it has weaker anti-Gram-positive bacterial effect. Ossamycin inhibits L cells, Epstein-Barr ascites cancer cells, KB cells, sarcoma-180 cells, L-1210 cells, HeLa cells in cell culture with IC₅₀s (μg/mL) of 0.007, 0.008, 0.005, 0.008, 0.003, 0.005, respectively .

HY-170844

MU147	Endonuclease	Cancer
MU147 is an MRE11 nuclease inhibitor and chemical probe with anticancer activity, which is lethal to Ehrlich ascites tumor cells both in vitro and in vivo. MU147 also eliminates the double-strand break repair mechanism dependent on the MRE11 nuclease activity without impairing the activation of ATM. MU147 also impairs the degradation of nascent strands of stalled replication FOX and selectively affects brca2-deficient cells .

HY-126170

Valanimycin	Antibiotic Bacterial	Infection Cancer
Valanimycin is an antibiotic, which inhibits Escherichia coli (BE1121) through interaction with DNA. Valanimycin exhibits cytotoxicity to mouse leukemia L1210, P388/S (doxorubicin (HY-15142A)-sensitive), and P388/ADR (doxorubicin-resistant), with IC₅₀ of 0.79, 2.65, and 1.44 μg/mL, respectively. Valanimycin exhibits antitumor efficacy against ehrlich ascites tumors or L1210 in mice .

HY-107430R

Oxythiamine (Standard) Hydroxythiamin (Standard)	Reference Standards Apoptosis Endogenous Metabolite	Cancer
Oxythiamine (Standard) is the analytical standard of Oxythiamine. This product is intended for research and analytical applications. Oxythiamine (Hydroxythiamin), an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis. Oxythiamine is a thiamine antagonist and inhibits transketolase (TK). Oxythiamine inhibits cancer cell apoptosis and inhibits cell proliferation[1][2][3].

HY-107430B

Oxythiamine chloride Hydroxythiamine chloride	Apoptosis	Cancer
Oxythiamine (Hydroxythiamine) chloride, an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis. Oxythiamine is a thiamine antagonist and inhibits transketolase (TK). Oxythiamine chloride inhibits cancer cell apoptosis and inhibits cell proliferation .

HY-W781133

cDPCP cis-[Pt(NH3)2(N1-pyridine)Cl]Cl	Others	Cancer
cDPCP (cis-[Pt(NH3)2(N1-pyridine)Cl]Cl) is a DNA crosslinking agent and also a substrate for OCT1 and OCT2. DPCP exhibits anticancer activity and can improve the survival rate of sarcoma-180 mice. cDPCP is suitable for the research of colorectal cancer and cancers with appropriate cation transporters .

HY-107430

Oxythiamine 2 Publications Verification Hydroxythiamin	Apoptosis Endogenous Metabolite	Cancer
Oxythiamine (Hydroxythiamin), an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis. Oxythiamine is a thiamine antagonist and inhibits transketolase (TK). Oxythiamine inhibits cancer cell apoptosis and inhibits cell proliferation .

Cat. No.	Product Name	Type

HY-D0085

DiSC3(5)

5+ Cited Publications

Fluorescent Dyes/Probes

DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

Cat. No.	Product Name	Target	Research Area

HY-P5535

Invopressin OCE-205	Vasopressin Receptor	Inflammation/Immunology
Invopressin (Compound 42) is a vasopressin V1A receptor partial agonist (EC₅₀: 1.0 nM). Invopressin can be used for research of cirrhosis, including bacterial peritonitis, HRS2 and refractory ascites .

HY-P3509A

PNC-28 acetate	MDM-2/p53	Cancer
PNC-28 acetate is a peptide from the mdm-2-binding domain (residues 17–26) of the p53 protein which contains a membrane crossing-penetratin sequence. PNC-28 acetate can be used for pancreatic cancer research .

HY-169684

Vaccarin C	Fungal	Infection Cancer
Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC₅₀ values of 3.35 and 5.72 μM, respectively .

HY-P3509

PNC-28	MDM-2/p53	Cancer
PNC-28 is a peptide from the mdm-2-binding domain (residues 17–26) of the p53 protein which contains a membrane crossing-penetratin sequence. PNC-28 can be used for pancreatic cancer research .

Cat. No.	Product Name

HY-K0242

Protein A Plus Magnetic Agarose Beads 1 Publications Verification
MCE Protein A Plus Magnetic Agarose Beads can be used for the detection and purification of IgG from serum, ascites fluid, cell culture supernatant and other antibody samples.

HY-K0243

Protein G Plus Magnetic Agarose Beads 2 Publications Verification
MCE Protein G Plus Magnetic Agarose Beads can be used for the detection and purification of IgG from serum, ascites fluid, cell culture supernatant and other antibody samples.

HY-K0251

Protein A Agarose (Alkali-Tolerant) 4FF
MCE Protein A Agarose (Alkali-Tolerant) 4FF can efficiently binds IgG from serum, ascites, culture supernatants, and other antibody-containing samples, enabling high-performance antibody purification.

Cat. No.	Product Name	Target	Research Area

HY-P99262

Imalumab BAX69; Anti-Human MIF Recombinant Antibody	Macrophage migration inhibitory factor (MIF)	Cancer
Imalumab (BAX69) is a recombinant, human IgG1 monoclonal antibody that targets macrophage inhibitory factor (MIF). Imalumab can be used for the research of ovarian carcinoma, recurrent malignant ascites and cancer .

HY-P9954

Catumaxomab	CD3	Cancer
Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers .

HY-P991526

M701	CD3	Cancer
M701 is a humanized bispecific CD3/EpCAM T-cell engager antibody. M701 effectively kill high EpCAM expressing cancer cells. M701 can be used for the study of malignant ascites and gastric cancer .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P86040

	MUC4 Antibody (YA5732) Mucin-4; MUC-4; ascites sialoglycoprotein; ASGP; Pancreatic adenocarcinoma mucin; Testis mucin; Tracheobronchial mucin; [Cleaved into: Mucin-4 alpha chain; ascites sialoglycoprotein 1; ASGP-1; Mucin-4 beta chain; ascites sialoglycoprotein 2; ASGP-2; ]	IHC-P, ICC/IF, ELISA	Human
	MUC4 Antibody (YA5732) is a mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MUC4. It can be applicated for IHC-P, ICC/IF, ELISA assays, in the background of human.

HY-P83519

	Mucin 4 Antibody (YA3264) Mucin-4; ascites sialoglycoprotein; ASGP; Pancreatic adenocarcinoma mucin; Testis mucin; Tracheobronchial mucin	WB	Human
	Mucin 4 Antibody (YA3264) is a non-conjugated IgG antibody, targeting Mucin 4, with a predicted molecular weight of 542 kDa (observed band size: 120 kDa). Mucin 4 Antibody (YA3264) can be used for WB experiment in human background.

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