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VEGFR-2-IN-77

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-179032
    VEGFR-2-IN-77

    		VEGFR PI3K Akt mTOR Apoptosis Cancer
    VEGFR-2-IN-77 (Compound 10) is a VEGFR-2 inhibitor with an IC50 value of 139 nM. VEGFR-2-IN-77 inhibits the PI3K/AKT/mTOR pathway. VEGFR-2-IN-77 exhibits selective cytotoxicity, being particularly sensitive to leukemia and prostate cancer cells. VEGFR-2-IN-77 causes cell cycle arrest and apoptosis, inhibiting cell migration and invasion. VEGFR-2-IN-77 can be used for the study of leukemia and prostate cancer.
    VEGFR-2-IN-77

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