2. Search Result
Search Result
Results for "

Uncaria

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

19

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6946
    Mitraphylline

    		NF-κB Inflammation/Immunology
    Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils .
    Mitraphylline
  • HY-N0901
    Corynoxine
    1 Publications Verification

    		 Autophagy Neurological Disease Cancer
    Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
    Corynoxine
  • HY-N2193
    Hirsutine
    1 Publications Verification

    		 Flavivirus Dengue Virus Apoptosis Infection Cancer
    Hirsutine, an indole alkaloid of Uncaria rhynchophylla, exhibits anti-cancer activity. Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity .
    Hirsutine
  • HY-N2197
    Hirsuteine

    		nAChR Neurological Disease
    Hirsuteine is an indole alkaloid extracted from Uncaria rhynchophylla. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes .
    Hirsuteine
  • HY-N0590
    Corynoxeine
    Maximum Cited Publications
    6 Publications Verification

    		 ERK Cardiovascular Disease
    Corynoxeine, isolated from the hook of Uncaria rhynchophylla, is a potent ERK1/ERK2 inhibitor of key PDGF-BB-induced vascular smooth muscle cells (VSMCs) proliferation.
    Corynoxeine
  • HY-N0387
    Rhynchophylline
    2 Publications Verification

    		 NF-κB Neurological Disease
    Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum. Rhyncholphylline is an EphA4 inhibitor. It has high biological activity and is widely used in anti-inflammatory, neuroprotective and other research. .
    Rhynchophylline
  • HY-N6946R
    Mitraphylline (Standard)

    		NF-κB Reference Standards Inflammation/Immunology
    Mitraphylline (Standard) is the analytical standard of Mitraphylline. This product is intended for research and analytical applications. Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils .
    Mitraphylline (Standard)
  • HY-N1112
    Uncargenin C

    		Others Cancer
    Uncargenin C is a triterpenoid, which can be isolated from Uncaria rhychophyllo Miq. Jacks. The intermediate of Uncargenin C has anti-leukemia activity, but not itself .
    Uncargenin C
  • HY-N0901B
    Corynoxine hydrochloride

    		Autophagy Neurological Disease Cancer
    Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
    Corynoxine hydrochloride
  • HY-N1792
    3,6,19,23-Tetrahydroxy-12-ursen-28-oic acid

    		Others Others
    3,6,19,23-Tetrahydroxy-12-ursen-28-oic acid is a Triterpenoids product that can be isolated from the herbs of Uncaria sessilifructus. .
    3,6,19,23-Tetrahydroxy-12-ursen-28-oic acid
  • HY-N1793
    3,6,19-Trihydroxy-23-oxo-12-ursen-28-oic acid

    		Others Others
    3,6,19-Trihydroxy-23-oxo-12-ursen-28-oic acid is a Triterpenoids product that can be isolated from the vines of Uncaria rhynchophylla .
    3,6,19-Trihydroxy-23-oxo-12-ursen-28-oic acid
  • HY-N1525
    Quinovic acid 3-O-(6-deoxy-β-D-glucopyranoside) 28-O-β-D-glucopyranosyl ester

    		Others Others
    Quinovic acid 3-O-(6-deoxy-β-D-glucopyranoside) 28-O-β-D-glucopyranosyl ester is a Triterpenoids product that can be isolated from the vines of Uncaria tomentosa .
    Quinovic acid 3-O-(6-deoxy-β-D-glucopyranoside) 28-O-β-D-glucopyranosyl ester
  • HY-N2411
    Geissoschizine methyl ether

    		5-HT Receptor Neurological Disease
    Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT1A receptor agonist .
    Geissoschizine methyl ether
  • HY-N0766R
    Isorhynchophylline (Standard)

    		SOD Reference Standards Others
    Isorhynchophylline (Standard) is the analytical standard of Isorhynchophylline. This product is intended for research and analytical applications. Isorhynchophylline is an alkaloid compound isolated from Uncaria. It can lower blood pressure, relax blood vessels, and protect nerves from damage caused by local ischemia.
    Isorhynchophylline (Standard)
  • HY-N1760
    3β, 19α-Dihydroxy-6-oxo-urs-12-en-23-al-28-oic acid

    		Others Others
    3β, 19α-Dihydroxy-6-oxo-urs-12-en-23-al-28-oic acid (compound 1) is a triterpene that can be isolated from Uncaria .
    3β, 19α-Dihydroxy-6-oxo-urs-12-en-23-al-28-oic acid
  • HY-N4157
    Isopteropodine

    		mAChR 5-HT Receptor Bacterial Neurological Disease
    Isopteropodine is a positive modulator that selectively acts on muscarinic M1 and 5-HT2 receptors. Isopteropodine has an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-HT. Isopteropodine also has antibacterial activity against Gram-positive bacteria, with MICs of 150 μg/mL and 250 μg/mL for Staphylococcus aureus and Bacillus subtilis, respectively. Isopteropodine enhances receptor function by increasing the affinity of agonists for receptors and can also inhibit the growth of specific Gram-positive bacteria, and can be used in cognitive impairment and antibacterial research .
    Isopteropodine
  • HY-N4157R
    Isopteropodine (Standard)

    		Reference Standards mAChR 5-HT Receptor Bacterial Neurological Disease
    Isopteropodine (Standard) is the analytical standard of Isopteropodine (HY-N4157). This product is intended for research and analytical applications. Isopteropodine is a positive modulator that selectively acts on muscarinic M1 and 5-HT2 receptors. Isopteropodine has an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-HT. Isopteropodine also has antibacterial activity against Gram-positive bacteria, with MICs of 150 μg/mL and 250 μg/mL for Staphylococcus aureus and Bacillus subtilis, respectively. Isopteropodine enhances receptor function by increasing the affinity of agonists for receptors and can also inhibit the growth of specific Gram-positive bacteria, and can be used in cognitive impairment and antibacterial research .
    Isopteropodine (Standard)
  • HY-N0590R
    Corynoxeine (Standard)

    		Reference Standards ERK Cardiovascular Disease
    Corynoxeine (Standard) is the analytical standard of Corynoxeine. This product is intended for research and analytical applications. Corynoxeine, isolated from the hook of Uncaria rhynchophylla, is a potent ERK1/ERK2 inhibitor of key PDGF-BB-induced vascular smooth muscle cells (VSMCs) proliferation.
    Corynoxeine (Standard)
  • HY-N0387R
    Rhynchophylline (Standard)

    		Reference Standards NF-κB Neurological Disease
    Rhynchophylline (Standard) is the analytical standard of Rhynchophylline. This product is intended for research and analytical applications. Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum. Rhyncholphylline is an EphA4 inhibitor. It has high biological activity and is widely used in anti-inflammatory, neuroprotective and other research. .
    Rhynchophylline (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: