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Results for "

Thrombin aptamer

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

4

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153480A
    ARC19499 sodium

    BAX499 sodium

    		 Factor Xa Factor VIIa Tissue Factor Pathway Inhibitor (TFPI) Others
    ARC19499 sodium is an aptamer that inhibits tissue factor pathway inhibitor (TFPI) , thereby enabling clot initiation and propagation via the extrinsic pathway. The core aptamer binds tightly and specifically to TFPI. ARC19499 sodium blocks TFPI inhibition of both factor Xa and the TF/factor VIIa complex. ARC19499 sodium corrects thrombin generation in hemophilia A and B plasma and restores clotting in FVIII-neutralized whole blood.
    ARC19499 sodium
  • HY-177804
    Thrombin aptamer sodium

    		Thrombin Inflammation/Immunology
    Thrombin aptamer is a 11mer-DNA aptamer that targets thrombin. Thrombin aptamer inhibites thrombin-catalysed fibrin-clot formation in vitro
    Thrombin aptamer sodium
  • HY-148826
    Rovunaptabin

    ARC 183; BC 007

    		 Thrombin Others
    Rovunaptabin (ARC 183) is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity and specificity.
    Rovunaptabin
  • HY-153480
    ARC19499

    BAX499

    		 Factor Xa Factor VIIa Tissue Factor Pathway Inhibitor (TFPI) Others
    ARC19499 is an aptamer that inhibits tissue factor pathway inhibitor (TFPI) , thereby enabling clot initiation and propagation via the extrinsic pathway. The core aptamer binds tightly and specifically to TFPI. ARC19499 blocks TFPI inhibition of both factor Xa and the TF/factor VIIa complex. ARC19499 corrects thrombin generation in hemophilia A and B plasma and restores clotting in FVIII-neutralized whole blood.
    ARC19499
  • HY-D1721
    Fluorescein-12-dATP

    		Fluorescent Dye Others
    Fluorescein-12-dATP is a fluorescent dye acting as the detection probe. Fluorescein-12-dATP can be used to label the thrombin-binding aptamers by catalytic polymerization of TdT (terminal deoxynucleotidyl transferase) . Fluorescein-12-dATP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Fluorescein-12-dATP

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