Search Result

Results for "

Tec

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) BCRP (1) BMX Kinase (1) Btk (9) ByeTAC (1) CDK (1) Epigenetic Reader Domain (1) FGFR (1) Fungal (1) PROTACs (1) Small Interfering RNA (siRNA) (4) Tyrosinase (3)
By Research Areas:	Cancer (9) Infection (1) Inflammation/Immunology (8) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (1) siRNAs (4)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-149051

BGB-8035	Btk	Inflammation/Immunology Cancer
BGB-8035 is an orally active, highly selective bruton's tyrosine kinase (BTK) inhibitor with IC₅₀s of 1.1 nM, 99 nM, 621 nM for BTK, TEC, EGFR, respectively. BGB-8035 has antitumor and anti-arthritis activity. BGB-8035 has the potential for B-cell malignancies and autoimmune diseases research .

HY-130665

TL12-186 1 Publications Verification	PROTACs CDK	Cancer
TL12-186 is a Cereblon-dependent multi-kinase PROTAC degrader. Multi-kinases include CDK, BTK, FLT3, Aurora kinases, *TEC, ULK, ITK, et al. TL12-186 inhibits CDK2/cyclin A* (IC₅₀=73 nM) and CDK9/cyclin T1 (IC₅₀=55 nM) .

HY-124827

Tec-IN-1	Tyrosinase	Cancer
Tec-IN-1 (Compound 21) is a *Tec* inhibitor (IC₅₀s of 11.7 μM). Tec-IN-1 inhibits Tec-mediated tyrosine phosphorylation of FGF2, and inhibits FGF2 secretion from cells .

HY-123541

Tec-IN-6	FGFR Tyrosinase	Cancer
Tec-IN-6 (compound 6) is a *FGF2 binding to Tec* kinase** inhibitor, with an IC₅₀ of 8.9 μM (His-FGF2/GST-NΔ173 Tec) .

HY-176071

TEC 4	ByeTAC Epigenetic Reader Domain	Cancer
TEC 4 is a ByeTAC (Bypassing E-Ligase-Targeting Chimera) BRD4 degrader, with 33% BRD4 remaining at 500 nM in Ramos B-cells. TEC 4 shows toxicity for Ramos B-cells, with an IC₅₀ of 30.5 nM. ByeTACs directly recruits a protein to the proteasome via interactions with Rpn-13 for degradation. Pink: BRD4 lignad (HY-78695); Blue: Rpn-13 ligand (HY-159808); Black: linker (HY-W008352) .

HY-RS17530

Tec Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tec Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tec gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tec Mouse Pre-designed siRNA Set A Tec Mouse Pre-designed siRNA Set A

HY-RS23986

Tec Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tec Rat Pre-designed siRNA Set A contains three designed siRNAs for Tec gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tec Rat Pre-designed siRNA Set A Tec Rat Pre-designed siRNA Set A

HY-RS14346

TEC Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TEC Human Pre-designed siRNA Set A contains three designed siRNAs for TEC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TEC Human Pre-designed siRNA Set A TEC Human Pre-designed siRNA Set A

HY-172432

Plodicitinib	Tyrosinase	Inflammation/Immunology
Plodicitinib is a Janus tyrosine kinase 3/TEC family kinase inhibitor with anti-inflammatory activity .

HY-117900A

(Rac)-PF-06250112	Btk	Inflammation/Immunology
(Rac)-PF-0625011 is a racemate of PF-06250112. PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor and shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC .

HY-N11772

Mutanocyclin	Fungal	Infection
Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse .

HY-117900

PF-06250112	Btk	Inflammation/Immunology
PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC₅₀ of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and *TEC* with IC₅₀s of 0.9 nM and 1.2 nM, respectively .

HY-145373

BMS-986143	Btk	Inflammation/Immunology
BMS-986143 is an orally active, reversible BTK inhibitor with an IC₅₀ of 0.26 nM. BMS-986143 also inhibits TEC, BLK, BMX, TXK FGR, YES1, ITK with IC₅₀s of 3 nM, 5 nM, 7 nM, 10 nM, 15 nM,19 nM, 21 nM, respectively. BMS-986143 can be used for the research of autoimmune diseases .

HY-RS18292

Nr4a3 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nr4a3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nr4a3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nr4a3 Mouse Pre-designed siRNA Set A Nr4a3 Mouse Pre-designed siRNA Set A

HY-18010

PCI 29732 3 Publications Verification	Btk BCRP	Inflammation/Immunology
PCI 29732 is a potent, orally active, reversible BTK inhibitor with K_i ^app values of 8.2, 4.6, and 2.5 nM for BTK, Lck and Lyn, respectively. PCI 29732 shows only modest inhibitory activity against Itk, another Tec family kinase. PCI 29732 inhibits the function of ABCG2 by competitively binding to the ATP-binding site of ABCG2 .

HY-80002

BMX-IN-1 5 Publications Verification BMX kinase inhibitor	Btk BMX Kinase	Cancer
BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys ⁴⁹⁶ in the BMX ATP binding domain with an IC₅₀ of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC₅₀ value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.

HY-174129

TM471-1	Btk Apoptosis	Cancer
TM471-1 is an orally active and covalent Bruton's tyrosine kinase (BTK) inhibitor with IC₅₀ values of 1.3 nM (BTK ^WT), >40,000 nM (BTK ^C481S), 7.9 nM (TEC) and 12.4 nM (TXK). TM471-1 inhibits cell growth in vivo and in vitro, arrests cell cycle at G0/G1 phase and induces cell apoptosis .

HY-142932

BTK-IN-6	Btk	Neurological Disease Inflammation/Immunology Cancer
BTK-IN-6 is a potent inhibitor of Bruton's Tyrosine Kinase (BTK). BTK is a member of the Tec family of tyrosine kinases and plays an important role in the regulation of early B-cell development and mature B-cell activation and survival. BTK-IN-6 has the potential for the research of immune disorders, cancer, cardiovascular diseases, viral infections, inflammation, metabolism/endocrine function disorders, and neurological disorders (extracted from patent WO2021136219A1, compound 8) .

HY-109143B

(R)-Elsubrutinib (R)-ABBV-105	Btk	Inflammation/Immunology Cancer
(R)-Elsubrutinib ((R)-ABBV-105) is a Btk inhibitor. (R)-Elsubrutinib can be used in studies of immune diseases (such as rheumatoid arthritis, psoriasis, ankylosing spondylitis, asthma, systemic lupus erythematosus) and cancer .

Mutanocyclin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse .

Species:	Human (3)
Tag:	His (1) Tag Free (1) GST (1)
Source:	Sf9 insect cells (2) P. pastoris (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P701644

	TEC Protein, Human (sf9) Tec; Tyrosine-protein kinase Tec	Human	Sf9 insect cells
	TEC proteins are dynamic nonreceptor tyrosine kinases that transduce signals in a variety of cellular processes. In adaptive immunity, TEC regulate T cell development, affecting IL2 gene induction and CD28 signaling. TEC Protein, Human (sf9) is the recombinant human-derived TEC protein, expressed by sf9 insect cells , with tag free.

HY-P701643

	TEC Protein, Human (sf9, GST) Tec; Tyrosine-protein kinase Tec	Human	Sf9 insect cells
	TEC proteins are dynamic nonreceptor tyrosine kinases that transduce signals in a variety of cellular processes. In adaptive immunity, TEC regulate T cell development, affecting IL2 gene induction and CD28 signaling. TEC Protein, Human (sf9, GST) is the recombinant human-derived TEC protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P71785

	SOCS1 Protein, Human (P.pastoris, His) CISH 1; CISH1; Cytokine inducible SH2 protein 1; JAB; JAK binding protein; JAK-binding protein; Janus kinase binding protein ; SOCS 1; Tec interacting protein 3; Tec-interacting protein 3; TIP 3	Human	P. pastoris
	The SOCS1 protein is an important negative regulator that inhibits type I and type II interferon signaling as well as cytokines such as IL2, IL4, IL6, and LIF. It downregulates the signaling of the JAK/STAT pathway by inhibiting JAK proteins and IFNGR1. SOCS1 Protein, Human (P.pastoris, His) is the recombinant human-derived SOCS1 protein, expressed by P. pastoris , with N-His labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80897

	SOCS1 Antibody SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3	ICC/IF, WB, IHC-F, IHC-P, ELISA	Human, Mouse, Rat
	SOCS1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 24 kDa, targeting to SOCS1. It can be used for ICC/IF,WB,IHC-F,IHC-P,ELISA assays with tag free, in the background of Human, Mouse, Rat.

HY-P85386

	Tec Antibody (YA5078) Tec; PSCTK4; Tyrosine-protein kinase Tec	WB, ELISA	Human
	Tec Antibody (YA5078) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Tec. It can be applicated for WB, ELISA assays, in the background of human.

HY-P82436

	Tec Antibody (YA2181) Tyrosine-protein kinase Tec	WB, ICC/IF	Human
	Tec Antibody (YA2181) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2181), targeting Tec, with a predicted molecular weight of 74 kDa (observed band size: 58-75 kDa). Tec Antibody (YA2181) can be used for WB, ICC/IF experiment in human background.

HY-P85715

	SOCS-1 Antibody (YA5407) Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3;	IHC-P, WB	Human, Mouse, Rat
	SOCS-1 Antibody (YA5407) is a mouse-derived and non-conjugated monoclonal antibody, targeting to SOCS-1. It can be applicated for IHC-P, WB assays, in the background of human, mouse, rat.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Tec Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Tec Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tec gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tec Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Tec Rat Pre-designed siRNA Set A contains three designed siRNAs for Tec gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

TEC Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TEC Human Pre-designed siRNA Set A contains three designed siRNAs for TEC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nr4a3 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Nr4a3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nr4a3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks