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Isoforms Recommended:	TEAD

Results for "

TEAD

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (4) Antibiotic (1) Apoptosis (5) Autophagy (2) Bacterial (1) c-Myc (1) Calcium Channel (4) Chloride Channel (4) COX (4) E3 Ligase Ligand-Linker Conjugates (1) Isotope-Labeled Compounds (2) Ligands for Target Protein for PROTAC (1) Parasite (4) Photosensitizer (1) Potassium Channel (4) PROTACs (2) Small Interfering RNA (siRNA) (12) Survivin (1) TAM Receptor (1) YAP (58)
By Research Areas:	Cancer (57) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (4)
Oligonucleotides:	Rat Pre-designed siRNA Sets (4) Mouse Pre-designed siRNA Sets (4) Human Pre-designed siRNA Sets (4) siRNAs (12)

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Isotope-Labeled Compounds

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-147088

TEAD-IN-2	YAP	Cancer
TEAD-IN-2 is a novel, orally active inhibitor of transcriptional enhancer associate domain *(TEAD)* and modulates TEAD by ubiquitination and/or degradation by compounds. TEAD-IN-2 can be used for the research of a variety of diseases, disorders or conditions associated with TEAD .

HY-163173

TEAD-IN-8	YAP	Cancer
TEAD-IN-8 is a novel *TEAD* inhibitor, which potently and specifically inhibits TEAD-YAP transcriptional activities. TM2, alone or in combination with MEK inhibitors, exhibits potent antiproliferative effects in YAP-dependent cancer cells .

HY-161569

TEAD-IN-11	YAP	Cancer
TEAD-IN-11 (compound 38) has a good inhibitory effect on *TEAD1* (IC₅₀=8.7 nM), *TEAD2* (IC₅₀=3.4 nM), *TEAD3* (IC₅₀=5.6 nnM). TEAD-IN-11 has good selective activity against *TEAD1-3* as a covalent inhibitor. TEAD-IN-11 can be used for cancer research .

HY-161568

TEAD-IN-10	YAP	Cancer
TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on *TEAD1* (IC₅₀=14 nM), *TEAD2* (IC₅₀=179 nM) and *TEAD3* (IC₅₀=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research .

HY-172932

TEAD-IN-20	YAP	Cancer
TEAD-IN-20 is a *TEAD* inhibitor. The IC₅₀ values of TEAD-IN-20 in TEAD4 FRET and TEAD4 MCF7-Tead cell lines are 0.021 and 0.044 μM, respectively. TEAD-IN-20 can be used in cancer research .

HY-137479

TEAD-IN-1	YAP	Cancer
TEAD-IN-1 (Compound 2) is potent TEAD autopalmitoylation inhibitor, with an IC₅₀ of 603 nM. TEAD-IN-1 increases the interaction of TEAD and VGLL4. TEAD-IN-1 decreases the interaction of YAP and TEAD. TEAD-IN-1 can be used for the research of cancer .

HY-161443

TEAD-IN-9	YAP	Cancer
TEAD-IN-9 (compound 17) is a *TEAD1* inhibitor with an IC₅₀ of 0.29 μM. TEAD-IN-9 targets the palmitoyl pocket of TEAD, thereby effectively inhibiting the binding of YAP-TEAD and blocking the transcriptional function of YAP-TEAD .

HY-173139

TEAD-IN-19	YAP	Cancer
TEAD-IN-19 (Compound 1l) is a transcriptional inhibitor of *TEAD, exhibiting inhibition rates of 38.5%, 36.2%, 57.8%, and 71.3% against TEAD1, TEAD2, TEAD3, and TEAD4, respectively, at a concentration of 10 μM. TEAD-IN-19 shows potent anti-proliferative and anti-migratory activities in prostate cancer cell lines and significantly reduces the expression of TEAD-regulated downstream genes. TEAD*-IN-19 holds promise for research in the field of cancer therapy .

HY-156024

TEAD-IN-6	YAP	Others
TEAD-IN-6 (Example 11-1) is a *TEAD* modulator that blocks the interaction between YAP1/TAZ and *TEAD. TEAD*-IN-6 can be used in cancer research .

HY-163732

TEAD-IN-16	YAP	Cancer
TEAD-IN-16 (compound BC-011) is a potent inhibitor of *TEAD, with the IC₅₀* of 72.43 μM. TEAD-IN-16 plays an important role in cancer research .

HY-158400

TEAD ligand 1	Ligands for Target Protein for PROTAC YAP	Cancer
TEAD ligand 1 is the ligand for target protein *TEAD. TEAD* ligand 1 is utilized for synthesis of PROTAC TEAD degrader-1 (HY-158342) .

HY-158395

TEAD-IN-13	YAP	Cancer
TEAD-IN-13 (64) is an orally active *TEAD* inhibitor, with an IC₅₀ of <100 nM and a half-life of 3.2 h in mouse .

HY-158396

TEAD-IN-14	YAP	Cancer
TEAD-IN-14 (75a) is an orally active *TEAD* inhibitor, with an IC₅₀ of <100 nM and a half-life of 2.3 h in mouse .

HY-158394

TEAD-IN-12	YAP	Cancer
TEAD-IN-12 (58B) is an orally active *TEAD* inhibitor, with an IC₅₀ of <100 nM and a half-life of 3.6 h in mouse .

HY-147135

MYF-03-69 TEAD-IN-3	YAP	Cancer
MYF-03-69 (TEAD-IN-3) is a potent and irreversible *TEAD* inhibitor. MYF-03-69 disrupts YAP-TEAD association, suppresses TEAD transcriptional activity and inhibits cell growth of Hippo signaling defective malignant pleural mesothelioma (MPM) .

HY-RS24777

Tead3 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tead3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tead3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tead3 Rat Pre-designed siRNA Set A Tead3 Rat Pre-designed siRNA Set A

HY-RS18299

Tead3 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tead3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tead3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tead3 Mouse Pre-designed siRNA Set A Tead3 Mouse Pre-designed siRNA Set A

HY-RS23528

Tead1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tead1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tead1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tead1 Rat Pre-designed siRNA Set A Tead1 Rat Pre-designed siRNA Set A

HY-RS19240

Tead2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tead2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tead2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tead2 Mouse Pre-designed siRNA Set A Tead2 Mouse Pre-designed siRNA Set A

HY-RS16870

Tead4 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tead4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tead4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tead4 Mouse Pre-designed siRNA Set A Tead4 Mouse Pre-designed siRNA Set A

HY-RS14345

TEAD4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TEAD4 Human Pre-designed siRNA Set A contains three designed siRNAs for TEAD4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TEAD4 Human Pre-designed siRNA Set A TEAD4 Human Pre-designed siRNA Set A

HY-RS23311

Tead4 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tead4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tead4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tead4 Rat Pre-designed siRNA Set A Tead4 Rat Pre-designed siRNA Set A

HY-RS14344

TEAD3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TEAD3 Human Pre-designed siRNA Set A contains three designed siRNAs for TEAD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TEAD3 Human Pre-designed siRNA Set A TEAD3 Human Pre-designed siRNA Set A

HY-RS14342

TEAD1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TEAD1 Human Pre-designed siRNA Set A contains three designed siRNAs for TEAD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TEAD1 Human Pre-designed siRNA Set A TEAD1 Human Pre-designed siRNA Set A

HY-RS25729

Tead2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tead2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tead2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tead2 Rat Pre-designed siRNA Set A Tead2 Rat Pre-designed siRNA Set A

HY-RS14343

TEAD2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TEAD2 Human Pre-designed siRNA Set A contains three designed siRNAs for TEAD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TEAD2 Human Pre-designed siRNA Set A TEAD2 Human Pre-designed siRNA Set A

HY-RS17084

Tead1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tead1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tead1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tead1 Mouse Pre-designed siRNA Set A Tead1 Mouse Pre-designed siRNA Set A

HY-170311

*YAP/TEAD-IN-1*	YAP	Cancer
YAP/TEAD-IN-1 (compound 4) is a potent YAP and *TEAD* inhibitor. YAP/TEAD-IN-1 shows antioxidant activity. YAP/TEAD-IN-1 shows antiproliferation activity for tumor cells. YAP/TEAD-IN-1 shows little cytotoxic activity for human normal cells .

HY-168704

*YAP/TAZ-TEAD-IN-2*	YAP TAM Receptor Survivin	Cancer
YAP/TAZ-TEAD-IN-2 (Compound 51) is a *YAP/TAZ-TEAD* inhibitor that inhibits the interaction between YAP/TAZ and TEAD. YAP/TAZ-TEAD-IN-2 suppresses the transcriptional activity of TEAD, with an IC₅₀ of 1.2 nM. YAP/TAZ-TEAD-IN-2 inhibits YAP/TAZ-TEAD target genes expression (Cyr61, CTGF, AXL and Survivin) and breast cancer cell proliferation .

HY-P2244

*YAP-TEAD-IN-1* 2 Publications Verification	YAP	Cancer
YAP-TEAD-IN-1 is a potent and competitive inhibitor of?YAP–TEAD interaction (IC₅₀=25 nM). YAP-TEAD-IN-1 is a 17mer peptide and shows a higher the binding affinity to TEAD1 (K_d=15 nM) than YAP (50-171) (K_d=40 nM) .

HY-159912

*pan-TEAD-IN-1*	YAP	Cancer
pan-TEAD-IN-1 (Compound 3) is an orally active pan-TEAD inhibitor targeting the palmitoylation site of *TEAD, disrupting its interaction with the coactivators YAP/TAZ, thereby suppressing the transcriptional upregulation of oncogenes (e.g., Ctgf* and Cyr61) in the Hippo signaling pathway. pan-TEAD-IN-1 exhibits excellent activity with a luciferase IC₅₀ of 0.36 nM and an H226 cell IC₅₀ of 1.52 nM. It also shows favorable pharmacokinetics (AUC_0–∞ = 228.7 μg/mL·min, T_1/2 = 183.9 min). In TEAD-dependent xenograft mouse models, pan-TEAD-IN-1 significantly inhibited tumor growth, showing promise for research in TEAD-dependent cancers .

HY-P2244A

*YAP-TEAD-IN-1 TFA* 2 Publications Verification	YAP	Cancer
YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of *YAP-TEAD* interaction (IC₅₀*=25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (K_d=15 nM) than YAP (50-171) (K_d*= 40 nM) .

HY-151525

*YAP-TEAD-IN-2*	YAP	Cancer
YAP-TEAD-IN-2 (compound 6) is a potent *YAP-TEAD* PPI (protein-protein interaction) inhibitor with IC₅₀** is 2.7 nM .

HY-153811

IAG933 YAP-TEAD-IN-3	YAP Apoptosis	Cancer
IAG933 (YAP-TEAD-IN-3) is an orally available *YAP/TAZ-TEAD* inhibitor that has anti-tumor effects and promotes apoptosis. IAG933 YAP-TEAD-IN-3 inhibits Avi-human TEAD ^4217-434, with an IC₅₀ value of 9 nM .

HY-158342

*PROTAC TEAD* degrader-1**	PROTACs YAP	Cancer
PROTAC TEAD degrader-1 (Compound 27) is a PROTAC degrader for transcriptional enhanced associate domain (TEAD). PROTAC TEAD degrader-1 selectively degrades the Flag TEAD2 in a ubiquitin proteasome-dependent manner, with a DC₅₀ of 54.1 nM in 293T cells, inhibits proliferation of NF2-deficient NCI-H226 with an IC₅₀ of 0.21 μM, and regulates expressions of yes associated protein (YAP) target genes. (Pink: TEAD ligand (HY-158400); Black: linker (HY-W008474); Blue: E3 ligase ligand (HY-W087383))

HY-139330

MGH-CP1	Apoptosis	Cancer
MGH-CP1 is a potent and orally active *TEAD2* and *TEAD4* auto-palmitoylation inhibitor with IC₅₀s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells. MGH-CP1 can suppress Myc expression, inhibit epithelial over-proliferation, and induce apoptosis when together with Lats1/2 deletion .

HY-147208

MSC-4106	YAP	Cancer
MSC-4106 is an orally active and potent inhibitor of *YAP/TAZ-TEAD. MSC-4106 inhibits TEAD1* or *TEAD3* auto-palmitoylation and shows inhibitory effect on NCI-H226 tumor xenograft model .

HY-138565

K-975 20+ Cited Publications	YAP	Cancer
K-975 is a potent, selective and orally active *TEAD* inhibitor, with a strong inhibitory effect against protein-protein interactions between YAP1/TAZ and TEAD. K-975 covalently binds to Cys359 located in the palmitate-binding pocket of TEAD via an acrylamide structure. K-975 exhibits antitumor activity on malignant pleural mesothelioma .

HY-160657

DC-TEADin04	YAP	Others
DC-TEADin04 has weak inhibitory activity against TEAD4 palmitoylation .

HY-155310

AF-2112	YAP	Cancer
AF-2112 is a Flufenamic acid-derived *TEAD* inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2.

HY-125269

TED-347 5+ Cited Publications	YAP	Cancer
TED-347 is a potent, irreversible, covalent and allosteric inhibitor at *YAP-TEAD* protein-protein interaction with an EC₅₀** of 5.9 μM for TEAD4⋅Yap1 protein-protein interaction. TED-347 specifically and covalently bonds with Cys-367 within the central pocket of TEAD4 with a K_i of 10.3 μM. TED-347 blocks TEAD transcriptional activity and has antitumor activity .

HY-155309

LM-41	YAP	Cancer
LM-41 is a Flufenamic acid-derived *TEAD* inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2. LM-41 inhibits migration of human MDA-MB-231 breast cancer cells .

HY-134955

VT103 2 Publications Verification	YAP	Cancer
VT103, an analog of VT101, is an orally active and selective *TEAD1* protein palmitoylation inhibitor. VT103 inhibits *YAP/TAZ-TEAD* promoted gene transcription, blocks *TEAD* auto-palmitoylation, and disrupts interaction between YAP/TAZ and *TEAD*. VT103 can be used for the research of cancer .

HY-147136

MYF-03-176	YAP	Cancer
MYF-03-176 is an orally active inhibitor of *TEAD, and suppresses TEAD* transcriptional activity with an IC₅₀ of 11 nM. The IC₅₀ values of MYF-03-176 for TEAD1, TEAD3, and TEAD4 are 47, 32, and 71 nM, respectively. MYF-03-176 inhibits hippo signaling defective malignant pleural mesothelioma (MPM) cells. MYF-03-176 shows strong antitumor efficacy in MPM mouse xenograft model .

HY-155338

SWTX-143	YAP	Cancer
SWTX-143 is an orally active *YAP*/TAZ-TEAD inhibitor that binds to the palmitoylation pocket of all four TEAD isoforms. SWTX-143 causes irreversible and specific inhibition of the transcriptional activity of YAP/TAZ-TEAD and shows antitumor activity .

HY-139603

MYF-01-37	YAP	Cancer
MYF-01-37 is a covalent *TEAD* inhibitor targeting Cys380. MYF-01-37 has a reversible inhibition on YAP/TEAD interaction .

HY-169316

YAP/TAZ inhibitor-4	YAP	Cancer
YAP/TAZ inhibitor-4 (Compound 45) is an inhibitor of YAP/TAZ, exhibiting *TEAD* transcriptional activation inhibitory activity by suppressing the binding of YAP or TAZ to *TEAD* .

HY-172113

H122	PROTACs YAP c-Myc	Cancer
H122 is a PROTAC degrader for *TEAD* that degrades *TEAD1* with a DC₅₀ of 3 nM, and exhibits good affinity to *TEAD2, TEAD3, and TEAD4* with K_i of 2.0, 3.6 and 1.6 nM. H122 downregulates the expression of Myc. H122 inhibits the cell growth of MSTO-211H and NCI-H226 with IC₅₀ of 21.3 nM and 0.6 nM, and exhibits antitumor efficacy in mouse models . (Pink: ligand for target protein (HY-151525); Black: linker (HY-W573128); Blue: ligand for E3 ligase Cereblon (HY-W087383))

HY-134956

VT104 1 Publications Verification	YAP	Cancer
VT104 is a potent and orally active YAP/TAZ inhibitor. VT104 prevents palmitoylation of endogenous TEAD1 and TEAD3 proteins. VT104 can be used in research of cancer .

HY-B1221

Flufenamic acid 5+ Cited Publications	COX AMPK Potassium Channel Chloride Channel Calcium Channel Parasite	Inflammation/Immunology
Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca ²⁺ channels, modulating non-selective cation channels (NSC), activating K ⁺ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.

Cat. No.	Product Name	Target	Research Area

HY-P2244

*YAP-TEAD-IN-1* 2 Publications Verification	YAP	Cancer
YAP-TEAD-IN-1 is a potent and competitive inhibitor of?YAP–TEAD interaction (IC₅₀=25 nM). YAP-TEAD-IN-1 is a 17mer peptide and shows a higher the binding affinity to TEAD1 (K_d=15 nM) than YAP (50-171) (K_d=40 nM) .

HY-P2244A

*YAP-TEAD-IN-1 TFA* 2 Publications Verification	YAP	Cancer
YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of *YAP-TEAD* interaction (IC₅₀*=25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (K_d=15 nM) than YAP (50-171) (K_d*= 40 nM) .

HY-B0990

Thiostrepton Maximum Cited Publications 21 Publications Verification	Bacterial Antibiotic YAP	Infection
Thiostrepton is a thiazole antibiotic which selectively inhibits FOXM1. FOXM1 binds to YAP/TEAD complex. YAP/TEAD/FOXM1 complex binding at regulatory regions of genes governing cell cycle may impact cell proliferation .

HY-P1727

Super-TDU 4 Publications Verification	YAP	Cancer
Super-TDU is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU suppresses tumor growth in gastric cancer mouse model .

HY-P1727A

Super-TDU TFA	YAP	Cancer
Super-TDU TFA is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU TFA suppresses tumor growth in gastric cancer mouse model .

HY-P1728

Super-TDU (1-31)	YAP	Cancer
Super-TDU (1-31) is a peptide fragment of Super-TDU. Super-TDU (1-31) is an inhibitor of *YAP-TEAD* complex. Super-TDU shows potent anti-tumor activity and suppresses tumor growth in gastric cancer mouse model .

HY-P1728A

Super-TDU (1-31) TFA	YAP	Cancer
Super-TDU (1-31) TFA is a peptide fragment of Super-TDU. Super-TDU (1-31) TFA is an inhibitor of *YAP-TEAD* complex. Super-TDU TFA shows potent anti-tumor activity and suppresses tumor growth in gastric cancer mouse model .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0990

Thiostrepton 20+ Cited Publications	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Other Antibiotics	Bacterial Antibiotic YAP
Thiostrepton is a thiazole antibiotic which selectively inhibits FOXM1. FOXM1 binds to YAP/TEAD complex. YAP/TEAD/FOXM1 complex binding at regulatory regions of genes governing cell cycle may impact cell proliferation .

Species:	Human (5) Mouse (1)
Tag:	His (3) SUMO (1) Tag Free (3) Strep (1)
Source:	Sf9 insect cells (3) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P71626

	TEAD3 Protein, Human (His-SUMO) DTEF 1; DTEF-1; DTEF1; ETFR 1; ETFR1; TEA domain family member 3; TEA domain family member 5; TEAD 3; TEAD-3; TEAD3; TEAD5; TEF 5; TEF5; Transcriptional enhancer factor 5	Human	E. coli
	TEAD3 protein is a transcription factor that plays a key role in the Hippo signaling pathway and is essential for organ size control and tumor suppression. It coordinates proliferation inhibition and apoptosis promotion through a kinase cascade involving MST1/MST2, SAV1, LATS1/2, and MOB1. TEAD3 Protein, Human (His-SUMO) is the recombinant human-derived TEAD3 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P71535

	TEAD4 Protein, Human (His) EFTR 2; EFTR2; hRTEF 1B; hRTEF1B; TEAD 4; TEAD-4; TEAD4; TEAD4_HUMAN; TEF 3; TEF3; TEFR 1; TEFR1; Transcription factor 13 (SV40 transcriptional enhancer factor) like 1; Transcription factor 13 like 1; Transcription factor 13-like 1; Transcription factor RTEF 1; Transcription factor RTEF-1; Transcription factor RTEF1; Transcriptional enhancer factor 1 related; Transcriptional enhancer factor 3	Human	E. coli
	TEAD4 protein is a transcription factor that plays a key role in the Hippo signaling pathway and is essential for organ size control and tumor suppression. It coordinates proliferation inhibition and apoptosis promotion through a kinase cascade involving MST1/MST2, SAV1, LATS1/2, and MOB1. TEAD4 Protein, Human (His) is the recombinant human-derived TEAD4 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71575

	*ETFR-2/TEAD-4 Protein, Mouse* ETF-related factor 2; ETFR-2; TEA domain family member 4; TEAD-4; TEF-1-related factor 1; TEF-1-related factor FR-19; RTEF-1	Mouse	E. coli
	ETFR-2/TEAD-4 protein is a key transcription factor that tightly regulates the Hippo signaling pathway and is an integral component of organ size control and tumor suppression. In this pathway, it mediates a kinase cascade involving MST1/MST2, SAV1, LATS1/2, and MOB1, leading to the inactivation of YAP1 and WWTR1/TAZ. ETFR-2/TEAD-4 Protein, Mouse is the recombinant mouse-derived ETFR-2/TEAD-4 protein, expressed by E. coli , with tag free.

HY-P703247

	TEAD2 Protein, Human (sf9, Depalmitoylated) TEF4	Human	Sf9 insect cells

HY-P703248

	TEAD2 Protein, Human (sf9, Biotinylated, Depalmitoylated) TEF4	Human	Sf9 insect cells
	TEAD2 Protein, Human (sf9, Biotinylated, Depalmitoylated) is the recombinant human-derived TEAD2, expressed by sf9 insect cells , with tag Free labeled tag. ,

HY-P703249

	TEAD2 Protein, Human (sf9, His, Depalmitoylated, Strep) TEF4	Human	Sf9 insect cells
	TEAD2 Protein, Human (sf9, His, Depalmitoylated, Strep) is the recombinant human-derived TEAD2, expressed by sf9 insect cells , with Strep, His labeled tag. ,

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HY-B1221S1

Flufenamic acid-13C6

Flufenamic acid- ¹³C₆ is the ¹³C₆ labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca ²⁺ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.

HY-B1221S

Flufenamic acid-d4

Flufenamic acid-d₄ is deuterium labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca ²⁺ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82209

	Transcriptional Enhancer Factor TEF 1 Antibody (YA1954) TEAD1; TCF13; TEF1; Transcriptional enhancer factor TEF-1; NTEF-1; Protein GT-IIC; TEA domain family member 1; TEAD-1; Transcription factor 13; TCF-13	WB, IHC-P, IP	Human, Mouse, Rat
	Transcriptional Enhancer Factor TEF 1 Antibody (YA1954) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1954), targeting Transcriptional Enhancer Factor TEF 1, with a predicted molecular weight of 48 kDa (observed band size: 52 kDa). Transcriptional Enhancer Factor TEF 1 Antibody (YA1954) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

HY-P82377

	Transcriptional Enhancer Factor TEF Antibody (YA2122) DTEF 1; NTEF 1; TCF13; TEAD1; TEAD2; TEAD3; TEAD4; TEAD5; TEF1; TEF4; TEF5	WB	Human
	Transcriptional Enhancer Factor TEF Antibody (YA2122) is a non-conjugated IgG antibody, targeting Transcriptional Enhancer Factor TEF, with a predicted molecular weight of 48 kDa (observed band size: 54 kDa). Transcriptional Enhancer Factor TEF Antibody (YA2122) can be used for WB experiment in human background.