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Results for "

Swertia

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

18

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2192
    Swertianolin

    		Bacterial p38 MAPK NF-κB NO Synthase Reactive Oxygen Species (ROS) Infection Neurological Disease Inflammation/Immunology
    Swertianolin is a xanthone glycoside. Swertianolin can be isolated from plants of the Gentianaceae family (e.g., Gentiana campestris and Swertia punicea). Swertianolin inhibits p38 phosphorylation and NF-κB activation, and reduces NO and ROS production. Swertianolin exhibits anti-Helicobacter pylori activity with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Swertianolin modulates immune function in sepsis. Swertianolin is useful in the research of diseases such as Alzheimer's disease, hepatitis B, Helicobacter pylori infection, and sepsis .
    Swertianolin
  • HY-N7116
    Lawsone methyl ether

    2-​Methoxy-​1,​4-​naphthoquinone

    		 Fungal Bacterial Infection
    Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone), isolated from Impatiens balsamina L. and Swertia calycina, exhibits potent antifungal and antibacterial activities .
    Lawsone methyl ether
  • HY-N11457
    Swertiaside

    		Others Others
    Swertiaside is a natural product, that can be isolated from Swertia mussotii Franch .
    Swertiaside
  • HY-N1994
    Swertianine

    		Reactive Oxygen Species (ROS) Inflammation/Immunology
    Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect .
    Swertianine
  • HY-N2192R
    Swertianolin (Standard)

    		Reference Standards Bacterial p38 MAPK NF-κB NO Synthase Reactive Oxygen Species (ROS) Infection Neurological Disease Inflammation/Immunology
    Swertianolin (Standard) is the analytical standard of Swertianolin (HY-N2192). This product is intended for research and analytical applications. Swertianolin is a xanthone glycoside. Swertianolin can be isolated from plants of the Gentianaceae family (e.g., Gentiana campestris and Swertia punicea). Swertianolin inhibits p38 phosphorylation and NF-κB activation, and reduces NO and ROS production. Swertianolin exhibits anti-Helicobacter pylori activity with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Swertianolin modulates immune function in sepsis. Swertianolin is useful in the research of diseases such as Alzheimer's disease, hepatitis B, Helicobacter pylori infection, and sepsis .
    Swertianolin (Standard)
  • HY-N3862
    Erythrodiol 3-O-palmitate

    		Others Cancer
    Erythrodiol 3-O-palmitate is a natural product isolated from Dicranostigma leptopodum (Maxim) Fedde, Gentiana rhodantha Franch or Swertia kouitchensis. Erythrodiol 3-O-palmitate has antitumor activity, and inhibits the proliferation of K562 cells with the inhibition rate of 47% at 100 ug/mL .
    Erythrodiol 3-O-palmitate
  • HY-N2873
    Angustin B

    		Others Others
    Angustin B is a Xanthones product that can be isolated from the aerial parts of Swertia angustifolia. .
    Angustin B
  • HY-N11530
    Kouitchenside G

    		Glycosidase Metabolic Disease
    Kouitchenside G is a natural product that can be isolated from Swertia kouitchensis. Kouitchenside G inhibits α-Glucosidase with an IC50 of 956 μM .
    Kouitchenside G
  • HY-N2872
    Angustin A

    		Others Others
    Angustin A (1,8-Dihydroxy-4,6,7-trimethoxyxanthone) is a xanthones that can be isolated from the aerial parts of Swertia angustifolia .
    Angustin A
  • HY-N11545
    1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone

    		Others Others
    1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone (Compound 18) is a natural product that can be isolated from Swertia mussotii .
    1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone
  • HY-N1995
    Methylswertianin

    		Others Metabolic Disease
    Methylswertianin is an active constituent in Swertia punicea Hemsl, with anti-diabetic effect. Methylswertianin can abates type-2 diabetes, likely via the improvement of insulin resistance (IR) .
    Methylswertianin
  • HY-N11512
    α-Glucosidase-IN-24

    		Glycosidase Metabolic Disease
    α-Glucosidase-IN-24 (Compound 13) is an α-Glucosidase inhibitor with an IC50 of 451 μM. α-Glucosidase-IN-24 can be isolated from Swertia kouitchensis .
    α-Glucosidase-IN-24
  • HY-N2050
    1,3,5,8-Tetrahydroxyxanthone
    1 Publications Verification

    Desmethylbellidifolin

    		 Others Neurological Disease Inflammation/Immunology
    1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Swertia chirata. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity .
    1,3,5,8-Tetrahydroxyxanthone
  • HY-N2000
    Bellidifolin

    		HIV Infection Inflammation/Immunology Cancer
    Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities . Bellidifolin also acts as a viral protein R (Vpr) inhibitor .
    Bellidifolin
  • HY-N9337
    Amaroswerin

    		NO Synthase Metabolic Disease Inflammation/Immunology Cancer
    Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells .
    Amaroswerin
  • HY-N13173
    α-Glucosidase-IN-70

    		Glycosidase Metabolic Disease
    α-Glucosidase-IN-70 (compound 9) is an α-glucosidase inhibitor (IC50=31.1 μM) isolated from the traditional Chinese herbal medicine Swertia mussotii. α-Glucosidase-IN-70 can be used in the research of diabetes .
    α-Glucosidase-IN-70
  • HY-N2447
    Amarogentin
    2 Publications Verification

    		 AMPK Apoptosis Metabolic Disease Cancer
    Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .
    Amarogentin
  • HY-N2447R
    Amarogentin (Standard)

    		Reference Standards AMPK Apoptosis Metabolic Disease Cancer
    Amarogentin (Standard) is the analytical standard of Amarogentin. This product is intended for research and analytical applications. Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .
    Amarogentin (Standard)

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