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Sweetener

" in MedChemExpress (MCE) Product Catalog:

161

Inhibitors & Agonists

1

Screening Libraries

5

Fluorescent Dye

7

Biochemical Assay Reagents

4

Peptides

62

Natural
Products

63

Isotope-Labeled Compounds

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W150251

    Biochemical Assay Reagents Others
    Dulcin is an artificial sweetener .
    Dulcin
  • HY-N12659

    Others Others
    Thaumatin B is a non-nutritive sweetener .
    Thaumatin B
  • HY-N0468

    Others Metabolic Disease
    Rebaudioside D is a glycoside found in the leaves of Stevia rebaudiana and acts as a sweetener .
    Rebaudioside D
  • HY-B1390B

    Bacterial Inflammation/Immunology
    Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties .
    Saccharin sodium hydrate
  • HY-Y0272

    Bacterial Inflammation/Immunology
    Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties .
    Saccharin
  • HY-B0541

    Cyclohexylsulfamic acid; Cyclamate

    Apoptosis Necroptosis Metabolic Disease Cancer
    Cyclamic acid (Cyclamate) is a commonly used sweetener. Cyclamic acid sodium is toxic to osteoblasts and can inhibit cell proliferation, induce apoptosis and reduce cell mineralization. Cyclamic acid sodium causes focal necrosis of bladder organs in rats in vitro, which can promote bladder cancer, but some studies have shown that low doses of Cyclamic acid sodium have no carcinogenic effect. In addition, Cyclamic acid sodium has no effect on insulin and glucagon secretion induced by arginine .
    Cyclamic acid
  • HY-129847

    Amino Acid Derivatives Others
    Alitame is a high-intensity sweetener formed from the amino acids L-aspartic acid and D-alanine, and an amine derived from thietane .
    Alitame
  • HY-N0468R

    Reference Standards Others Metabolic Disease
    Rebaudioside D (Standard) is the analytical standard of Rebaudioside D. This product is intended for research and analytical applications. Rebaudioside D is a glycoside found in the leaves of Stevia rebaudiana and acts as a sweetener .
    Rebaudioside D (Standard)
  • HY-W550739

    Biochemical Assay Reagents Neurological Disease
    Acesulfame is an artificial sweetener. Acesulfame affects cognitive functions, potentially via altering neuro-metabolic functions in mice with long-term .
    Acesulfame
  • HY-N15373

    (+)-Abrusoside A

    Others Others
    Abrusoside A is a highly sweet triterpene glycoside isolated from the leaves of Abrus precatorius. Abrusoside A has potential application value as a sweetener .
    Abrusoside A
  • HY-108968

    Taste Receptor Others
    Alitame (hydrate) is a high-intensity sweetener formed from the amino acids L-aspartic acid and D-alanine, and an amine derived from thietane .
    Alitame hydrate
  • HY-D0195R

    Biochemical Assay Reagents Reference Standards Neurological Disease Metabolic Disease
    Acesulfame (potassium) (Standard) is the analytical standard of Acesulfame (potassium). This product is intended for research and analytical applications. Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice .
    Acesulfame potassium (Standard)
  • HY-N6833R

    Reference Standards Others Others
    Rebaudioside M (Standard) is the analytical standard of Rebaudioside M. This product is intended for research and analytical applications. Rebaudioside M, a glycoside of the ent-kaurene diterpenoid aglycone, is a non-calorie sweetener isolated from Stevia rebaudiana. Rebaudioside M is more than 350 times sweeter than sucrose .
    Rebaudioside M (Standard)
  • HY-N0614
    Sucralose
    2 Publications Verification

    E955; Trichlorosucrose

    Endogenous Metabolite Cancer
    Sucralose (E955; Trichlorosucrose) is a non-nutritive artificial sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents .
    Sucralose
  • HY-B0361
    Aspartame
    1 Publications Verification

    SC-18862

    Biochemical Assay Reagents Neurological Disease
    Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener .
    Aspartame
  • HY-N0669
    Stevioside
    3 Publications Verification

    Apoptosis Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Stevioside is an orally active sweetener that can be isolated from Stevia rebaudiana, with antihypertensive, antihyperglycemic, antioxidant, anti-inflammatory and anti-tumor activities .
    Stevioside
  • HY-B1390BR

    Reference Standards Bacterial Inflammation/Immunology
    Saccharin (sodium hydrate) (Standard) is the analytical standard of Saccharin (sodium hydrate). This product is intended for research and analytical applications. Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties .
    Saccharin sodium hydrate (Standard)
  • HY-Y0272R

    Reference Standards Bacterial Inflammation/Immunology
    Saccharin (Standard) is the analytical standard of Saccharin. This product is intended for research and analytical applications. Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties .
    Saccharin (Standard)
  • HY-N6833

    Others Metabolic Disease Inflammation/Immunology Cancer
    Rebaudioside M, a glycoside of the ent-kaurene diterpenoid aglycone, is a non-calorie sweetener isolated from Stevia rebaudiana. Rebaudioside M has antidiabetics, antihypertension, anti-inflammatory, antioxidant, anticaries and anticancer benefits. Rebaudioside M is more than 350 times sweeter than sucrose. Rebaudioside M can be used in food and beverage .
    Rebaudioside M
  • HY-B0400
    D-Sorbitol
    1 Publications Verification

    Sorbitol; D-Glucitol

    Endogenous Metabolite Bacterial Others
    D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol
  • HY-108968R

    Taste Receptor Reference Standards Others
    Alitame (hydrate) (Standard) is the analytical standard of Alitame (hydrate). This product is intended for research and analytical applications. Alitame (hydrate) is a high-intensity sweetener formed from the amino acids L-aspartic acid and D-alanine, and an amine derived from thietane .
    Alitame hydrate (Standard)
  • HY-N0614R

    E955 (Standard); Trichlorosucrose (Standard)

    Reference Standards Endogenous Metabolite Cancer
    Sucralose (Standard) is the analytical standard of Sucralose. This product is intended for research and analytical applications. Sucralose?(E955; Trichlorosucrose) is a?non-nutritive?artificial?sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents .
    Sucralose (Standard)
  • HY-122351

    Drug Derivative Taste Receptor Others
    Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
    Advantame free acid
  • HY-B0361R

    SC-18862 (Standard)

    Biochemical Assay Reagents Reference Standards Neurological Disease
    Aspartame (Standard) is the analytical standard of Aspartame. This product is intended for research and analytical applications. Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener .
    Aspartame (Standard)
  • HY-W145497

    Insulin Receptor Metabolic Disease
    D-(+)-Sorbose, an active enantiomer of D-Sorbose, which inhibits disaccharidase activity and demonstrates suppressive action on postprandial blood levels of glucose and insulin in the rat. D-sorbose acts as a sweetener may contribute to the prevention of lifestyle-related diseases, such as type 2 diabetes mellitus .
    D-(+)-Sorbose
  • HY-N0669R

    Reference Standards Apoptosis Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Stevioside (Standard) is the analytical standard of Stevioside. This product is intended for research and analytical applications. Stevioside is an orally active sweetener that can be isolated from Stevia rebaudiana, with antihypertensive, antihyperglycemic, antioxidant, anti-inflammatory and anti-tumor activities .
    Stevioside (Standard)
  • HY-B0400R

    Sorbitol (Standard); D-Glucitol (Standard)

    Reference Standards Endogenous Metabolite Bacterial Others
    D-Sorbitol (Standard) is the analytical standard of D-Sorbitol. This product is intended for research and analytical applications. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol (Standard)
  • HY-N13208

    MMP TGF-beta/Smad Others
    Stevia Powder is a natural sweetener with antioxidant activity. Stevia Powder can downregulate pro fibrotic pathways in cirrhotic rats, including reduced hepatic myofibroblasts and decreased expression of matrix metalloproteinases MMP2 and MMP13, upregulate anti fibrotic molecule Smad7, prevent serum necrosis and elevated bile stasis markers, thereby inhibiting the development of liver fibrosis .
    Stevia Powder
  • HY-W011053

    Taste Receptor Apoptosis Drug Derivative Metabolic Disease
    Neotame is a derivative of Aspartame (HY-B0361) and is a flavor enhancer and low-caloric, non-nutritive, high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame causes intestinal epithelial cell death at high concentrations. Neotame induces Apoptosis of Caco-2 cells .
    Neotame
  • HY-W044525

    Phosphodiesterase (PDE) Metabolic Disease Inflammation/Immunology
    Phyllodulcin is an orally active sweetener found in Hydrangea macrophylla var. thunbergii. Phyllodulcin acts as a non-selective phosphodiesterase inhibitor and exerts anti-allergic effects by suppressing lymphocyte activation. Phyllodulcin can be used to combat obesity by regulating levels of leptin, fat browning-related genes, and hypothalamic BDNF-TrkB signaling .
    Phyllodulcin
  • HY-D0195

    PD-1/PD-L1 ERK mTOR Autophagy Neurological Disease Metabolic Disease
    Acesulfame potassium is a synthetic sweetener. Long-term use of Acesulfame potassium can affect cognitive function, possibly by altering the neurometabolic functions in mice. Acesulfame potassium can suppress autophagic degradation of PD-L1 in RIL-175 and SK-Hep1 cells through the ERK1/2-mTORC1-ULK1 pathway, which may be related to immune evasion in cancer cells. Acesulfame potassium can be used in research on neurological diseases, metabolic disorders, cancer, and immune evasion .
    Acesulfame potassium
  • HY-N2362

    DL-2-Aminopropionic acid

    Endogenous Metabolite Metabolic Disease
    DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .
    DL-Alanine
  • HY-113133

    Glycosidase Infection Metabolic Disease Inflammation/Immunology
    Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo .
    Kojibiose
  • HY-B1390A

    Bacterial Infection
    Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro .
    Saccharin sodium
  • HY-B1390AR

    Bacterial Reference Standards Infection
    Saccharin (sodium) (Standard) is the analytical standard of Saccharin (sodium). This product is intended for research and analytical applications. Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro .
    Saccharin sodium (Standard)
  • HY-113133R

    Reference Standards Glycosidase Infection Metabolic Disease Inflammation/Immunology
    Kojibiose (Standard) is the analytical standard of Kojibiose. This product is intended for research and analytical applications. Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo[1][2].
    Kojibiose (Standard)
  • HY-N6815

    Others Others
    Isomogroside V is a sweetener, which extracted from Siraitia grosvenorii (Swingle).
    Isomogroside V
  • HY-139312

    Endogenous Metabolite Others
    L-mannitol is a compound can be used for  the compound sweetener synthesis .
    L-Mannitol
  • HY-W011053S

    Isotope-Labeled Compounds Others
    (R)-Neotame-d3 is the deuterium labeled Neotame. Neotame is a derivative of Aspartame and is a low-caloric and high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame is a non-nutritive sweetener and flavor enhancer that can be used in a variety of foods .
    (R)-Neotame-d3
  • HY-N6889

    Others Others
    Rebaudioside I is a natural non-claoric sweetener isolated from S. rebaudiana Morita .
    Rebaudioside I
  • HY-N0154
    Neohesperidin dihydrochalcone
    3 Publications Verification

    Neohesperidin DC; NHDC

    Reactive Oxygen Species (ROS) Inflammation/Immunology
    Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener.
    Neohesperidin dihydrochalcone
  • HY-N2291

    Others Others
    Rebaudioside G is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni, used for sweeteners research .
    Rebaudioside G
  • HY-N6814

    Others Metabolic Disease Cancer
    Mogroside IIe is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities .
    Mogroside IIe
  • HY-N0500

    Others Metabolic Disease Cancer
    Mogroside III is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities .
    Mogroside III
  • HY-108275

    Biochemical Assay Reagents Metabolic Disease Cancer
    Mogroside VI is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities .
    Mogroside VI
  • HY-N6855

    Others Metabolic Disease Cancer
    Mogroside IIA1 is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities .
    Mogroside IIA1
  • HY-N2456
    Mogroside IV-E
    1 Publications Verification

    Others Metabolic Disease Cancer
    Mogroside IV-E, a triterpenoid glycoside, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities .
    Mogroside IV-E
  • HY-N2084
    Perillartine
    1 Publications Verification

    DL-Perillartine

    Endogenous Metabolite Others
    Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.
    Perillartine
  • HY-N6854

    Others Metabolic Disease Cancer
    Mogroside I A1 is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities .
    Mogroside I A1
  • HY-N6853

    DNA/RNA Synthesis AMPK Metabolic Disease Cancer
    Mogroside I E1 is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities .
    Mogroside I E1

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