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Sordarin

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

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Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126396
    Sordarin sodium

    		Antibiotic CaMK Fungal Infection
    Sordarin sodium is an eEF2 inhibitor and antibiotic. Sordarin sodium's function is dependent on the diphthamide modification on eEF2. Sordarin sodium inhibits protein synthesis by preventing the binding of eEF2 to the ribosome complex. Sordarin sodium has antifungal activity .
    Sordarin sodium
  • HY-128478
    Sordarin

    		Fungal Infection
    Sordarin (Compound 1) is an antifungal agent targeting Elongation factor 2 (EF2) with a tetracyclic diterpene core including a norbornene system. Sordarin can be isolated from the fungus Sordaria araneosa. Sordarin has potent antifungal activity against Saccharomyces cerevisiae and Candida albicans. Sordarin prevents the translocation of the ribosome along mRNA during elongation of the emerging polypeptide chain, inhibiting protein synthesis in fungi by stabilizing the ribosome/EF2 complex .
    Sordarin

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