1. Search Result
Search Result
Results for "

STa

" in MedChemExpress (MCE) Product Catalog:

25

Inhibitors & Agonists

5

Peptides

6

Natural
Products

17

Recombinant Proteins

1

Isotope-Labeled Compounds

2

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14934

    STa 5312

    Microtubule/Tubulin Cancer
    Rosabulin (STA 5312) is a potent and orally active microtubule inhibitor that inhibits microtubule assembly. Rosabulin has broad-spectrum anti-tumor activity .
    Rosabulin
  • HY-15205
    Ganetespib
    30+ Cited Publications

    STa-9090

    HSP Apoptosis Cancer
    Ganetespib (STA-9090) is a heat shock protein 90 (HSP90) inhibitor which exhibits potent cytotoxicity in a wide variety of hematological and solid tumor cell lines. Ganetespib has antiangiogenic effects in colorectal cancer mediated through inhibition of HIF-1α and STAT3 .
    Ganetespib
  • HY-12040
    Elesclomol
    Maximum Cited Publications
    55 Publications Verification

    STa-4783

    Reactive Oxygen Species (ROS) Apoptosis Cuproptosis Cancer
    Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death (cuproptosis). Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research .
    Elesclomol
  • HY-14644A
    Apilimod mesylate
    25+ Cited Publications

    STa 5326 mesylate; LAM-002A; AIT-101 mesylate

    Interleukin Related PIKfyve Inflammation/Immunology Cancer
    Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
    Apilimod mesylate
  • HY-RS17358

    STa

    Small Interfering RNA (siRNA) Others

    Emd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Emd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Emd Mouse Pre-designed siRNA Set A
    Emd Mouse Pre-designed siRNA Set A
  • HY-RS04345

    STa; EDMD; LEMD5

    Small Interfering RNA (siRNA) Others

    EMD Human Pre-designed siRNA Set A contains three designed siRNAs for EMD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EMD Human Pre-designed siRNA Set A
    EMD Human Pre-designed siRNA Set A
  • HY-RS27165

    STa; Smp-2; St2; St2a1; Sth2

    Small Interfering RNA (siRNA) Others
    Sult2a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sult2a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Sult2a1 Rat Pre-designed siRNA Set A
    Sult2a1 Rat Pre-designed siRNA Set A
  • HY-117051

    HSP Cancer
    STA-2842 is an inhibitor of heat shock protein HSP90 with potential to inhibit autosomal dominant polycystic kidney disease (ADPKD). ADPKD is caused by inherited mutations in the PKD1 or PKD2 genes that abnormally activate multiple signaling proteins and pathways that regulate cell proliferation. STA-2842 can significantly reduce initial renal cyst formation and kidney growth in mice, and slow disease progression in mice with existing cysts.
    STA-2842
  • HY-136945

    IFNAR Cancer
    StA-IFN-1 is an inhibitor for type I interferon (IFN), that inhibits the activation of IFNβ with an IC50 of 4.1 μM .
    StA-IFN-1
  • HY-12040S

    STa-4783-d2

    Isotope-Labeled Compounds Reactive Oxygen Species (ROS) Apoptosis Cuproptosis Cancer
    Elesclomol-d2 (STA-4783-d2) is a deuterium labeled Elesclomol (HY-12040). Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death (cuproptosis). Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research .
    Elesclomol-d2
  • HY-14644
    Apilimod
    25+ Cited Publications

    STa 5326; LAM-002A free base; AIT-101

    Interleukin Related PIKfyve Inflammation/Immunology Cancer
    Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
    Apilimod
  • HY-14644B

    STa 5326 hydrochloride; LAM-002A (free base) hydrochloride; AIT-101 hydrochloride

    NOD-like Receptor (NLR) Infection Inflammation/Immunology
    Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
    Apilimod hydrochloride
  • HY-121482

    STa-21

    STAT Inflammation/Immunology Cancer
    (+)-Ochromycinone is a natural antibiotic that potently inhibits STAT3. (+)-Ochromycinone is used in the researches of cancers and psoriasis .
    (+)-Ochromycinone
  • HY-RS00958

    GEF3; STa3; XPLN

    Small Interfering RNA (siRNA) Others

    ARHGEF3 Human Pre-designed siRNA Set A contains three designed siRNAs for ARHGEF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ARHGEF3 Human Pre-designed siRNA Set A
    ARHGEF3 Human Pre-designed siRNA Set A
  • HY-18061
    Ochromycinone
    3 Publications Verification

    (Rac)-STa-21

    Antibiotic STAT Bacterial Infection Cancer
    Ochromycinone ((Rac)-STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity .
    Ochromycinone
  • HY-18061R

    (Rac)-STa-21 (STandard)

    Antibiotic Reference Standards STAT Bacterial Infection Cancer
    Ochromycinone (Standard) ((Rac)-STA-21 (Standard)) is the analytical standard of Ochromycinone (HY-18061). This product is intended for research and analytical applications. Ochromycinone is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity.
    Ochromycinone (Standard)
  • HY-P1962

    [Asn670, STa671, Val672]-Amyloid β Peptide (662-675)

    Beta-secretase Neurological Disease
    β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase) .
    β-Secretase inhibitor
  • HY-79638

    4-Cyanophenacyl bromide

    Biochemical Assay Reagents Others
    4-(2-Bromoacetyl)benzonitrile (4-Cyanophenacyl bromide) can be used to the synthesis of STA-5312. STA-5312 is a potent and orally active microtubule inhibitor .
    4-(2-Bromoacetyl)benzonitrile
  • HY-N0931
    Santacruzamate A
    10+ Cited Publications

    CAY-10683

    HDAC Amyloid-β Neurological Disease Cancer
    Santacruzamate A (CAY-10683, STA) is a potent and selective HDAC2 inhibitor with an IC50 of 119 pM. STA also exerts neuroprotective property against amyloid-β protein fragment 25–35. STA can be used for cancer and neurological disease research .
    Santacruzamate A
  • HY-N0931R

    CAY-10683 (STandard)

    Reference Standards HDAC Amyloid-β Neurological Disease Cancer
    Santacruzamate A (Standard) is the analytical standard of Santacruzamate A. This product is intended for research and analytical applications. Santacruzamate A (CAY-10683, STA) is a potent and selective HDAC2 inhibitor with an IC50 of 119 pM. STA also exerts neuroprotective property against amyloid-β protein fragment 25–35. STA can be used for cancer and neurological disease research[1][2].
    Santacruzamate A (Standard)
  • HY-P0018
    Pepstatin
    35+ Cited Publications

    PepSTatin A

    HIV Protease Autophagy Infection Inflammation/Immunology
    Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease .
    Pepstatin
  • HY-P0018A
    Pepstatin Trifluoroacetate
    35+ Cited Publications

    PepSTatin A Trifluoroacetate

    HIV Protease Autophagy Infection Inflammation/Immunology
    Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Trifluoroacetate also inhibits HIV protease .
    Pepstatin Trifluoroacetate
  • HY-120757

    Virus Protease Others
    LP-130 is a statin-based inhibitor that is a universal inhibitor with nanomolar inhibitory activity against all tested retroviral proteases. Crystal structure studies of its binding to different retroviral proteases have shown that it can adapt to different active site regions to achieve inhibition.
    LP-130
  • HY-401913

    Phosphodiesterase (PDE) Infection Cancer
    Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC50 is 4 μM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model .
    endo CNTinh-03
  • HY-P2147

    Z-Arg-Arg-Pro-Phe-His-STa-Ile-His-Lys(Boc)-Ome

    Renin Others
    CGP 29287 is a specific renin inhibitor .
    CGP 29287

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: