SSB

By Targets:	Apoptosis (1) CXCR (1) DNA/RNA Synthesis (3) Isotope-Labeled Compounds (1) PARP (6) PPAR (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (8) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W159870

N-Nitrosodibenzylamine	DNA/RNA Synthesis	Others
N-Nitrosodibenzylamine is a potent and orally activity DNA damage inducer. N-Nitrosodibenzylamine induces DNA single-strand breaks (SSBs) .

HY-137457

Venadaparib 1 Publications Verification IDX-1197	PARP	Cancer
Venadaparib (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC₅₀s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib does not sensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSB) and can be used for solid tumors research .

HY-145804

Palacaparib 1 Publications Verification AZD-9574	PPAR	Neurological Disease Cancer
AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 acts by selectively inhibiting and trapping PARP1 at the sites of SSBs. AZD-9574 is an anti-cancer agent and can be used for HRD ⁺?breast cancer and advanced solid malignancies research .

HY-172154

SSB-2548	CXCR Apoptosis	Cancer
SSB-2548 is a CXCR-4 inhibitor. SSB-2548 can inhibit the proliferation, migration and induce apoptosis of acute myeloid leukemia cells. SSB-2548 has good gastrointestinal absorption and can be used in the research of leukemia .

HY-RS13804

SSB Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SSB Human Pre-designed siRNA Set A contains three designed siRNAs for SSB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SSB Human Pre-designed siRNA Set A SSB Human Pre-designed siRNA Set A

HY-RS23567

Ssb Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ssb Rat Pre-designed siRNA Set A contains three designed siRNAs for Ssb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ssb Rat Pre-designed siRNA Set A Ssb Rat Pre-designed siRNA Set A

HY-RS17122

Ssb Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)
Ssb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ssb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ssb Mouse Pre-designed siRNA Set A Ssb Mouse Pre-designed siRNA Set A

HY-132267S

N-Nitrosodibenzylamine-d4	Isotope-Labeled Compounds DNA/RNA Synthesis	Others
N-Nitrosodibenzylamine-d₄ is deuterium labeled N-Nitrosodibenzylamine. N-Nitrosodibenzylamine is a potent and orally activity DNA damage inducer. N-Nitrosodibenzylamine induces DNA single-strand breaks (SSBs) .

HY-W159870R

N-Nitrosodibenzylamine (Standard)	DNA/RNA Synthesis	Others
N-Nitrosodibenzylamine (Standard) is the analytical standard of N-Nitrosodibenzylamine. This product is intended for research and analytical applications. N-Nitrosodibenzylamine is a potent and orally activity DNA damage inducer. N-Nitrosodibenzylamine induces DNA single-strand breaks (SSBs) .

HY-10617R

Rucaparib phosphate (Standard) AG-014699 phosphate (Standard); PF-01367338 phosphate (Standard)	PARP	Cancer
Rucaparib (phosphate) (Standard) is the analytical standard of Rucaparib (phosphate). This product is intended for research and analytical applications. Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research[1][2][3][4].

HY-10617

Rucaparib phosphate Maximum Cited Publications 42 Publications Verification AG-014699 phosphate; PF-01367338 phosphate	PARP	Cancer
Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K_i of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research .

HY-10617A

Rucaparib Maximum Cited Publications 42 Publications Verification AG014699; PF-01367338	PARP	Cancer
Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K_i of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research .

HY-102003A

Rucaparib camsylate AG014699 camsylate; PF-01367338 camsylate	PARP	Cancer
Rucaparib (AG014699) camsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K_i of 1.4 nM for PARP1. Rucaparib camsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib camsylate has the potential for castration-resistant prostate cancer (CRPC) research .

HY-102003

Rucaparib monocamsylate Maximum Cited Publications 42 Publications Verification AG014699 monocamsylate; PF-01367338 monocamsylate	PARP	Cancer
Rucaparib (AG014699) monocamsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K_i of 1.4 nM for PARP1. Rucaparib monocamsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib monocamsylate has the potential for castration-resistant prostate cancer (CRPC) research .

Species:	Human (4)
Tag:	His (3) Tag Free (1)
Source:	Sf9 insect cells (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P73630A

	SSB Protein, Human Lupus La protein; Sjoegren syndrome type B antigen; SS-B	Human	E. coli
	The SSB protein critically binds to the 3' poly(U) terminus of RNA polymerase III transcripts, preventing exonuclease digestion and aiding in correct folding. In coxsackievirus B3 infection, SSB binds to the viral internal ribosome entry site (IRES) and enhances IRES-mediated translation. SSB Protein, Human is the recombinant human-derived SSB protein, expressed by E. coli , with tag free.

HY-P73630

	SSB Protein, Human (His) Lupus La protein; Sjoegren syndrome type B antigen; SS-B	Human	E. coli
	The SSB protein critically binds to the 3' poly(U) terminus of RNA polymerase III transcripts, preventing exonuclease digestion and aiding in correct folding. In coxsackievirus B3 infection, SSB binds to the viral internal ribosome entry site (IRES) and enhances IRES-mediated translation. SSB Protein, Human (His) is the recombinant human-derived SSB protein, expressed by E. coli , with N-His labeled tag.

HY-P73629

	SSB Protein, Human (sf9, His) Lupus La protein; Sjoegren syndrome type B antigen; SS-B	Human	Sf9 insect cells
	The SSB protein critically binds to the 3' poly(U) terminus of RNA polymerase III transcripts, preventing exonuclease digestion and aiding in correct folding. In coxsackievirus B3 infection, SSB binds to the viral internal ribosome entry site (IRES) and enhances IRES-mediated translation. SSB Protein, Human (sf9, His) is the recombinant human-derived SSB protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P703378

	SPSB4 Protein, Human (His) SSB4	Human	E. coli
	SPSB4 Protein, Human (His) is the recombinant human-derived SPSB4, expressed by E. coli , with His labeled tag. ,

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Cat. No.	Product Name	Chemical Structure

HY-132267S

N-Nitrosodibenzylamine-d4
N-Nitrosodibenzylamine-d₄ is deuterium labeled N-Nitrosodibenzylamine. N-Nitrosodibenzylamine is a potent and orally activity DNA damage inducer. N-Nitrosodibenzylamine induces DNA single-strand breaks (SSBs) .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80901

	SSB Antibody (YA668) La; LARP3; La/SSB	WB	Human
	SSB Antibody (YA668) is a non-conjugated and Mouse origined monoclonal antibody about 47 kDa, targeting to SSB (4B10). It can be used for WB assays with tag free, in the background of Human.

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Cat. No.	Product Name		Classification

HY-RS13804

SSB Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SSB Human Pre-designed siRNA Set A contains three designed siRNAs for SSB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23567

Ssb Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ssb Rat Pre-designed siRNA Set A contains three designed siRNAs for Ssb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17122

Ssb Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ssb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ssb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Recombinant Proteins

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