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Ro 40-7592 (Standard)

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17406R
    Tolcapone (Standard)

    Ro 40-7592 (Standard)

    		 Reference Standards COMT Amyloid-β Apoptosis Reactive Oxygen Species (ROS) Neurological Disease Cancer
    Tolcapone (Standard) (Ro 40-7592 (Standard)) is the analytical standard of Tolcapone (HY-17406). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma .
    Tolcapone (Standard)
  • HY-100642R
    3-O-Methyltolcapone (Standard)

    Ro 40-7591 (Standard)

    		 Reference Standards Drug Metabolite COMT Amyloid-β Apoptosis Reactive Oxygen Species (ROS) Neurological Disease Cancer
    3-O-Methyltolcapone (Standard) (Ro 40-7591 (Standard)) is the analytical standard of 3-O-Methyltolcapone (HY-174062). 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone (HY-17406). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma .
    3-O-Methyltolcapone (Standard)

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