Rab7

By Targets:	Apoptosis (1) Autophagy (1) Endogenous Metabolite (1) Integrin (1) Ras (6) Small Interfering RNA (siRNA) (3) YAP (1)
By Research Areas:	Cancer (6) Infection (1) Inflammation/Immunology (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13452

CID-1067700 10+ Cited Publications ML282	Ras	Inflammation/Immunology
CID-1067700 (ML282) is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a K_i of 13 nM.

HY-118208

ML-097 1 Publications Verification CID-2160985	Ras	Cancer
ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, and *Rab7* .

HY-124306

ML-099 2 Publications Verification CID-888706	Ras	Cancer
ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, *Rab7, and Rab-2A* .

HY-19800

ML-098 5+ Cited Publications CID-7345532	Ras	Cancer
ML-098 (CID-7345532) is an activator of the GTP-binding protein *Rab7* with an EC₅₀ of 77.6 nM.

HY-113849

MLS-573151 1 Publications Verification MLS000573151	Ras	Inflammation/Immunology
MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC₅₀ of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42 .

HY-RS23154

Rab7a Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Rab7a Rat Pre-designed siRNA Set A contains three designed siRNAs for Rab7a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Rab7a Rat Pre-designed siRNA Set A Rab7a Rat Pre-designed siRNA Set A

HY-RS11576

RAB7A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RAB7A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB7A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RAB7A Human Pre-designed siRNA Set A RAB7A Human Pre-designed siRNA Set A

HY-RS11577

RAB7B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RAB7B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB7B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RAB7B Human Pre-designed siRNA Set A RAB7B Human Pre-designed siRNA Set A

HY-P10038

mP6 Myr-FEEERA-OH	Integrin	Infection
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα₁₃ with integrin β₃ without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells .

HY-173150

YAP-IN-1	YAP	Cancer
YAP-IN-1 (Compound (+)-1) is an autophagy (Autophagy) inhibitor targeting YAP1. YAP-IN-1 binds to the Hippo pathway transcription factor YAP1 with a K_d of 9.13 μM and induces its degradation via the chaperone-mediated autophagy (CMA) pathway. This process inhibits *Rab7*-mediated fusion of autophagosomes and lysosomes, thereby reducing overall autophagy levels without affecting lysosomal function. YAP-IN-1 holds promise for research in cancer (e.g., liver cancer, breast cancer, etc.) .

HY-12755

ML141 Maximum Cited Publications 26 Publications Verification CID-2950007	Ras Apoptosis	Cancer
ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC₅₀s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines .

HY-W011209

N6-Isopentenyladenosine 1 Publications Verification Riboprine	Autophagy Endogenous Metabolite	Cancer
N6-Isopentenyladenosine (Riboprine), an RNA modification found in cytokinins, which regulate plant growth/differentiation, and a subset of tRNAs, where it improves the efficiency and accuracy of translation. N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with an interesting anti-melanoma activity .

Cat. No.	Product Name	Target	Research Area

HY-P10038

mP6 Myr-FEEERA-OH	Integrin	Infection
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα₁₃ with integrin β₃ without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W011209

N6-Isopentenyladenosine 1 Publications Verification Riboprine	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Autophagy Endogenous Metabolite
N6-Isopentenyladenosine (Riboprine), an RNA modification found in cytokinins, which regulate plant growth/differentiation, and a subset of tRNAs, where it improves the efficiency and accuracy of translation. N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with an interesting anti-melanoma activity .

Species:	Human (1) Rat (2)
Tag:	His (2) GST (1)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P75998

	RAB7A Protein, Rat (His, solution) Ras-related protein Rab-7a; Ras-related protein BRL-RAS; Rab7A; Rab7	Rat	E. coli
	RAB7A is a dynamic small GTPase that coordinates endolysosomal trafficking by cycling between a GTP-bound state and a GDP-bound state. In its active state, RAB7A interacts with various effectors, affecting endosomal maturation, microtubule directed migration, and endosome-lysosomal trafficking. RAB7A Protein, Rat (His,solution) is the recombinant rat-derived RAB7A protein, expressed by E. coli , with N-His labeled tag.

HY-P75998A

	RAB7A Protein, Rat (N-His) Ras-related protein Rab-7a; Ras-related protein BRL-RAS; Rab7A; Rab7	Rat	E. coli
	RAB7A is a dynamic small GTPase that coordinates endolysosomal trafficking by cycling between a GTP-bound state and a GDP-bound state. In its active state, RAB7A interacts with various effectors, affecting endosomal maturation, microtubule directed migration, and endosome-lysosomal trafficking. RAB7A Protein, Rat (N-His) is the recombinant rat-derived RAB7A, expressed by E. coli , with N-His labeled tag. ,

HY-P703254

	RAB29 Protein, Human (GST) Rab7L1	Human	E. coli
	RAB29 Protein, Human (GST) is the recombinant human-derived RAB29, expressed by E. coli , with GST labeled tag. ,

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HY-P82053

	Rab7B Antibody (YA1798) Rab7	WB	Human
	Rab7B Antibody (YA1798) is a non-conjugated IgG antibody, targeting Rab7B, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). Rab7B Antibody (YA1798) can be used for WB experiment in human background.

HY-P80295

	RAB7 Antibody (YA110) 1 Publications Verification CMT2B antibody; PRO2706 antibody; PSN antibody; Rab7, member RAS oncogene family antibody; Rab7A antibody; Rab7A, member RAS oncogene family antibody; Rab7A_HUMAN antibody; Ras associated protein Rab7 antibody; Ras related protein Rab7 antibody; Ras related protein Rab7a antibody	WB, ICC/IF, IHC-P, FC	Human, Mouse
	RAB7 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 23 kDa, targeting to RAB7. It can be used for WB,ICC/IF,IHC-P,FC assays with tag free, in the background of Human, Mouse.

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Cat. No.	Product Name		Classification

HY-RS23154

Rab7a Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Rab7a Rat Pre-designed siRNA Set A contains three designed siRNAs for Rab7a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS11576

RAB7A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
RAB7A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB7A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS11577

RAB7B Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
RAB7B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB7B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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