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  4. RAB29 Protein, Human (GST)

RAB29 Protein, Human (GST) is the recombinant human-derived RAB29, expressed by E. coli , with GST labeled tag. ,

For research use only. We do not sell to patients.

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Description

RAB29 Protein, Human (GST) is the recombinant human-derived RAB29, expressed by E. coli , with GST labeled tag. ,
Background

RAB29 is a small GTPase that serves as a key regulator in vesicle trafficking. It is essential for maintaining the structural integrity of the endosome-trans-Golgi network (by similarity). In collaboration with LRRK2, RAB29 participates in the retromer-dependent retrograde trafficking pathway, recycling proteins such as the mannose 6 phosphate receptor (M6PR) between lysosomes and the Golgi apparatus. Additionally, RAB29 recruits LRRK2 to the Golgi complex and enhances its kinase activity, promoting LRRK2-mediated phosphorylation of RAB10 at Thr-73. Within the intact central nervous system (CNS), RAB29 regulates neuronal process morphology (by similarity). Studies also suggest a potential role for RAB29 in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S. typhi) infection of epithelial cells.
Species

Human
Source

E. coli
Tag

GST
Accession

O14966-1 (M1-S177, Q67L, T71A, S72A)
Gene ID

8934
Protein Length

Partial
Synonyms
RAB7L1
Predicted Molecular Mass
47 kDa
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

RAB29 Protein, Human (GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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