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Results for "

RSK

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Ribosomal S6 Kinase (RSK) (28) Akt (2) AMPK (1) Apoptosis (16) Aurora Kinase (2) Autophagy (1) Bcl-2 Family (2) Caspase (2) Checkpoint Kinase (Chk) (7) Cryptochrome (2) DNA/RNA Synthesis (2) DYRK (1) EGFR (2) Endogenous Metabolite (2) ERK (13) FAK (2) FGFR (1) Keap1-Nrf2 (2) LIM Kinase (LIMK) (1) MAP3K (1) MAPKAPK2 (MK2) (1) mTOR (1) NEKs (2) NF-κB (2) p38 MAPK (3) PARP (2) PI3K (1) PI5P4K (1) PROTACs (2) Raf (1) Ras (1) Reference Standards (3) ROCK (1) Small Interfering RNA (siRNA) (4) Src (2) YB-1 (2)
By Research Areas:	Cancer (47) Cardiovascular Disease (4) Inflammation/Immunology (9) Metabolic Disease (2)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (3) siRNAs (4)

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Ribosomal S6 Kinase (RSK)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-132891

RSK4-IN-1	Ribosomal S6 Kinase (RSK)	Cancer
RSK4-IN-1 is a potent *RSK4* inhibitor with a IC₅₀ value of 9.5 nM. RSK4-IN-1 has antitumor activity .

HY-132891A

RSK4-IN-1 TFA	Ribosomal S6 Kinase (RSK)	Cancer
RSK4-IN-1 TFA is a potent *RSK4* inhibitor with a IC₅₀ value of 9.5 nM. RSK4-IN-1 TFA has antitumor activity .

HY-12185

BRD7389 1 Publications Verification	Ribosomal S6 Kinase (RSK)	Metabolic Disease Cancer
BRD7389 is a specific *RSK* family kinase inhibitor with IC₅₀s of 1.5 μM, 2.4 μM, and 1.2 μM for *RSK1, RSK2, and RSK3*, respectively. BRD7389 is a small-molecule inducer of insulin expression in pancreatic α-cells .

HY-10510

BI-D1870 15+ Cited Publications	Ribosomal S6 Kinase (RSK) Autophagy	Cancer
BI-D1870 is an ATP-competitive, cell permeable and brain penetrated inhibitor of *RSK* isoforms, with IC₅₀s of 31 nM/24 nM/18 nM/15 nM for RSK1/RSK2/RSK3/RSK4, respectively .

HY-10579

Pluripotin SC1	Ribosomal S6 Kinase (RSK) ERK	Cancer
Pluripotin is a dual inhibitor of ERK1 and RasGAP with K_Ds of 98 nM and 212 nM, respectively. Pluripotin also inhibits *RSK1, RSK2, RSK3, and RSK4* with IC₅₀s of 0.5, 2.5, 3.3, and 10.0 μM, respectively.

HY-173406

RSK-IN-2	Ribosomal S6 Kinase (RSK) Apoptosis	Cancer
RSK-IN-2 (Compound 3e) is a *RSK* inhibitor, with IC₅₀ s of 37.89 nM (RSK2), 30.78 nM (RSK1), 20.51 nM (RSK3), 91.28 nM (RSK4). RSK-IN-2 inhibits tumor cell proliferation, induces apoptosis and causes cell cycle arrest in the G2/M phase .

HY-150643

RSK2-IN-2	Ribosomal S6 Kinase (RSK)	Cancer
RSK2-IN-2 (Compound 25) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase. RSK2-IN-2 is also described to inhibit MSK1, MSK2 and *RSK3* .

HY-W286614

RSK2-IN-4	Ribosomal S6 Kinase (RSK)	Inflammation/Immunology Cancer
RSK2-IN-4 (Compound 10) is a *RSK2* inhibitor, with an inhibition rate of 13.73% on *RSK2* activity at 10 μM. RSK2-IN-4 binds to the ATP-binding site of *RSK2* in the NTKD (N-terminal kinase domain), with the electron-donating group at the 4-position of the phenyl ring being the key determinant for its inhibitory activity .

HY-144434

RSK-IN-1	Ribosomal S6 Kinase (RSK) YB-1	Cancer
RSK-IN-1 (compound 7d) is a *RSK* inhibitor that inhibits the YB-1 phosphorylation. RSK-IN-1 has anti-tumor effects .

HY-150717

RSK2-IN-3	Ribosomal S6 Kinase (RSK)	Cancer
RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase .

HY-19713

LJI308 4 Publications Verification	Ribosomal S6 Kinase (RSK) YB-1	Cancer
LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC₅₀s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation .

HY-52101A

FMK 3 Publications Verification	Ribosomal S6 Kinase (RSK)	Cancer
FMK is a an irreversible *RSK2* kinase inhibitor, that covalently modifies the C-terminal kinase domain of RSK.

HY-19712

LJH685 4 Publications Verification	Ribosomal S6 Kinase (RSK) Apoptosis	Cancer
LJH685 is a potent, ATP-competitive and selective *RSK* inhibitor, inhibits RSK1, 2, and 3 biochemical activities with IC₅₀s of 6, 5, 4 nM, respectively .

HY-15237

SL 0101-1 5 Publications Verification SL0101	Ribosomal S6 Kinase (RSK)	Cancer
SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC₅₀ of 89 nM . SL 0101-1 (SL0101) is a selective *RSK1/2* inhibitor, with a K_i of 1 μM .

HY-P10042

S6K Substrate	Ribosomal S6 Kinase (RSK)	Others
S6K Substrate is a substrate for active protein kinases, including CLK2, MRCKalpha, MRCKbeta, p70S6K, ROCK1, ROCK2, RSK1, RSK3, PIM1 .

HY-P3814

S6 Kinase Substrate Peptide 32	Ribosomal S6 Kinase (RSK)	Cancer
S6 Kinase Substrate Peptide 32 is a substrate of Ribosomal S6 Kinase (RSK). S6 Kinase Substrate Peptide 32 can be used to measure the activity of RSKs which phosphorylate ribosomal protein S6 .

HY-116533

RMM-46	MAPKAPK2 (MK2)	Cancer
RMM-46 is a selective and reversible covalent inhibitor for MSK/RSK-family kinases .

HY-52101C

FMK-MEA	Ribosomal S6 Kinase (RSK)	Cancer
FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.

HY-113592

ERK-IN-4	ERK	Cancer
ERK-IN-4 is an ERK inhibitor binds preferentially to ERK2 with a K_d of 5 μM. ERK-IN-4 specificity inhibits ERK Rsk-1 and Elk-1 phosphorylation. ERK-IN-4 has little effect on ERK protein phosphorylation by its upstream activator MEK1/2 .

HY-16104

BIX 02565 5+ Cited Publications	Ribosomal S6 Kinase (RSK)	Cardiovascular Disease
BIX 02565 is a potent ribosomal S6 kinase 2 (RSK2) inhibitor with IC₅₀ of 1.1 nM.

HY-52101

CMK 5+ Cited Publications	Ribosomal S6 Kinase (RSK)	Cancer
CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK.

HY-W838814

ERK1/2 inhibitor 12	ERK	Cancer
ERK1/2 inhibitor 12 (compound 76.3) is a ERK1/2 inhibitor which inhibits ERK-mediated phosphorylation of caspase-9 and the p90Rsk-1 kinase. ERK1/2 inhibitor 12 exhibits anti-cancer activity and can be utilized in cancer research .

HY-157133

TAS0612	Akt Ribosomal S6 Kinase (RSK) Apoptosis	Cancer
TAS0612 is the orally active inhibitor of *RSK、AKT* and S6K. TAS0612 has antitumor activity .

HY-N1374

Magnolin 1 Publications Verification	ERK	Inflammation/Immunology
Magnolin, a major component of Magnolia liliiflora, inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC₅₀s of 87 nM and 16.5 nM, respectively.

HY-119699

PV1115	Checkpoint Kinase (Chk)	Cancer
PV1115 is a potent and highly selective Chk2 inhibitor with an IC₅₀ of 0.14 nM, 66000 nM, >100000 nM for Chk2, Chk1 and RSK2, respectively. PV1115 is situated within the ATP-binding pocket of Chk2 .

HY-14362

GSK-25	ROCK Ribosomal S6 Kinase (RSK)	Cardiovascular Disease
GSK-25 is a potent, selective and orally bioavailable ROCK1 inhibitor (IC₅₀=7 nM). GSK-25 maintains good selectivity against a panel of 31 kinases (>100 fold), as well as RSK1 and p70S6K (RSK1: IC₅₀=398 nM, p70S6K: IC₅₀=1 μM). GSK-25 inhibits P450 profile (IC₅₀s of 2.5, 5.2, 2.5 µM for CYP2C9, CYP2D6, CYP3A4, respectively) .

HY-N1374R

Magnolin (Standard)	Reference Standards ERK	Inflammation/Immunology
Magnolin (Standard) is the analytical standard of Magnolin. This product is intended for research and analytical applications. Magnolin, a major component of Magnolia liliiflora, inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC₅₀s of 87 nM and 16.5 nM, respectively.

HY-N0643

Carnosol 10+ Cited Publications	Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite	Cancer
Carnosol is a potent Ribosomal S6 Kinase *(RSK2)* inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

HY-101494

Temuterkib 25+ Cited Publications LY3214996	ERK	Cancer
Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC₅₀ of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations.

HY-114038

SB-747651A	p38 MAPK	Inflammation/Immunology
SB-747651A is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor with an IC₅₀ of 11 nM. SB-747651A also inhibits PRK2, RSK1, p70S6K and ROCK-II. SB-747651A can be used for inflammation research .

HY-15816A

Ulixertinib hydrochloride Maximum Cited Publications 36 Publications Verification BVD-523 hydrochloride; VRT752271 hydrochloride	ERK	Cancer
Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC₅₀ of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line .

HY-110313

SB-747651A dihydrochloride	p38 MAPK	Inflammation/Immunology
SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor with an IC₅₀ of 11 nM. SB-747651A dihydrochloride also inhibits PRK2, RSK1, p70S6K and ROCK-II. SB-747651A dihydrochloride can be used for inflammation research .

HY-125911

Gossypin	NF-κB Aurora Kinase Ribosomal S6 Kinase (RSK) Apoptosis Caspase Bcl-2 Family PARP Cryptochrome	Cardiovascular Disease Inflammation/Immunology Cancer
Gossypin is an orally active flavone isolated from Hibiscus vitifolius. Gossypin has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits AURKA and *RSK2. Gossypin inhibits invasion and induces apoptosis*. Gossypin can be used for gastric cancer study .

HY-RS12248

RPS6KA1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RPS6KA1 Human Pre-designed siRNA Set A contains three designed siRNAs for RPS6KA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RPS6KA1 Human Pre-designed siRNA Set A RPS6KA1 Human Pre-designed siRNA Set A

HY-139188

CC260	PI5P4K	Metabolic Disease Cancer
CC260 is a selective PI5P4Kα and PI5P4Kβ inhibitor with K_is of 40 nM and 30 nM, respectively. CC260 does not inhibit or weakly inhibits other protein kinases, such as Plk1 and RSK2. CC260 can be used for cell energy metabolism, diabetes and cancer research .

HY-N0643R

Carnosol (Standard)	Reference Standards Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite	Cancer
Carnosol (Standard) is the analytical standard of Carnosol. This product is intended for research and analytical applications. Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

HY-15816

Ulixertinib Maximum Cited Publications 36 Publications Verification BVD-523; VRT752271	ERK	Cancer
Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC₅₀ of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line .

HY-12072

Lck Inhibitor 1 Publications Verification	Src	Inflammation/Immunology
Lck Inhibitor is a potent, orally active Lck (lymphocyte specific kinase) inhibitor with IC₅₀s of 7, 2.1, 4.2 and 200 nM for Lck, Lyn, Src and Syk kinases, respectively. Lck Inhibitor shows >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Lck Inhibitor inhibits T cell proliferation and in vivo models of arthritis .

HY-161633

PROTAC EGFR degrader 11	PROTACs EGFR FAK	Cancer
PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC₅₀ <100 nM. PROTAC EGFR degrader 11 binds CRBN-DDB1 with a K_i of 36 nM. PROTAC EGFR degrader 11 degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC₅₀ <100 nM.

HY-18174A

Prexasertib dihydrochloride 25+ Cited Publications LY2606368 dihydrochloride	Checkpoint Kinase (Chk) Apoptosis	Cancer
Prexasertib dihydrochloride (LY2606368 dihydrochloride) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib dihydrochloride inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib dihydrochloride causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dihydrochloride shows potent anti-tumor activity .

HY-161632

PROTAC EGFR degrader 10	PROTACs EGFR FAK	Cancer
PROTAC EGFR degrader 10 (Compound B56) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC₅₀ <100 nM. PROTAC EGFR degrader 10 binds CRBN-DDB1 with a K_i of 37 nM. PROTAC EGFR degrader 10 degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC₅₀ <150 nM .

HY-18174B

Prexasertib Mesylate Hydrate LY2606368 Mesylate Hydrate; LY2940930	Checkpoint Kinase (Chk) Apoptosis	Cancer
Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib Mesylate Hydrate inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib Mesylate Hydrate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib Mesylate Hydrate shows potent anti-tumor activity .

HY-18174C

Prexasertib mesylate LY2606368 mesylate	Checkpoint Kinase (Chk) DNA/RNA Synthesis Apoptosis	Cancer
Prexasertib mesylate (LY2606368 mesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib mesylate inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib mesylate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib mesylate shows potent anti-tumor activity .

HY-18174

Prexasertib 25+ Cited Publications LY2606368	Checkpoint Kinase (Chk) Apoptosis	Cancer
Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib shows potent anti-tumor activity .

HY-125911R

Gossypin (Standard)	Reference Standards NF-κB Aurora Kinase Ribosomal S6 Kinase (RSK) Apoptosis Bcl-2 Family Caspase Cryptochrome	Cardiovascular Disease Inflammation/Immunology Cancer
Gossypin (Standard) is the analytical standard of Gossypin. This product is intended for research and analytical applications. Gossypin is an orally active flavone isolated from Hibiscus vitifolius. Gossypin has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits AURKA and *RSK2. Gossypin inhibits invasion and induces apoptosis*. Gossypin can be used for gastric cancer study.

HY-108959

D-87503	ERK PI3K mTOR	Cancer
D-87503 is a potent inhibitor of PI3k/Akt/mTOR, with the IC₅₀s of 62 nM and 0.76 μM, respectively for PI3k and Erk2. D-87503 effectively suppressed the target downstream substrates Akt and *Rsk1* kinase of the PI3k/Akt/mTOR signaling pathway .

HY-18174E

Prexasertib dimesylate 25+ Cited Publications LY2606368 dimesylate	Checkpoint Kinase (Chk) Apoptosis	Cancer
Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib dimesylate inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib dimesylate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dimesylate shows potent anti-tumor activity .

HY-15816R

Ulixertinib (Standard)	ERK	Cancer
Ulixertinib (Standard) is the analytical standard of Ulixertinib. This product is intended for research and analytical applications. Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line .

HY-110313R

SB-747651A dihydrochloride (Standard)	p38 MAPK	Inflammation/Immunology
SB-747651A (dihydrochloride) (Standard) is the analytical standard of SB-747651A (dihydrochloride). This product is intended for research and analytical applications. SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor with an IC50 of 11 nM. SB-747651A dihydrochloride also inhibits PRK2, RSK1, p70S6K and ROCK-II. SB-747651A dihydrochloride can be used for inflammation research .

HY-18174H

Prexasertib lactate LY2606368 lactate	Checkpoint Kinase (Chk) Apoptosis DNA/RNA Synthesis	Cancer
Prexasertib lactate (LY2606368 lactate) is the lactate form of Prexasertib (HY-18174). Prexasertib lactate is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib lactate inhibits CHK2 (IC₅₀=8 nM) and *RSK1* (IC₅₀=9 nM). Prexasertib lactate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib lactate shows potent anti-tumor activity .

Cat. No.	Product Name

HY-L010

MAPK Compound Library

785 compounds

MAPK families play an important role in complex cellular programs like proliferation, differentiation, development, transformation, and apoptosis. In mammalian cells, four MAPK families have been clearly characterized: ERK1/2, C-Jun N-terminal kinse/stress-activated protein kinase (JNK/SAPK) , p38 kinase and ERK5. They respond to different signals. Each MAPK-related cascade consists of three enzymes that are activated in series: a MAPK kinase kinase (MAPKKK), a MAPK kinase (MAPKK) and a MAP kinase (MAPK). MAPK signaling pathways has been implicated in the development of many human diseases including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and various types of cancers.

MCE designs a unique collection of 785 MAPK signaling pathway inhibitors that act as a useful tool for MAPK-related drug screening and disease research.

Cat. No.	Product Name	Target	Research Area

HY-P10042

S6K Substrate	Ribosomal S6 Kinase (RSK)	Others
S6K Substrate is a substrate for active protein kinases, including CLK2, MRCKalpha, MRCKbeta, p70S6K, ROCK1, ROCK2, RSK1, RSK3, PIM1 .

HY-P3814

S6 Kinase Substrate Peptide 32	Ribosomal S6 Kinase (RSK)	Cancer
S6 Kinase Substrate Peptide 32 is a substrate of Ribosomal S6 Kinase (RSK). S6 Kinase Substrate Peptide 32 can be used to measure the activity of RSKs which phosphorylate ribosomal protein S6 .

Species:	Human (8)
Tag:	His (3) Tag Free (2) GST (4)
Source:	Sf9 insect cells (6) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P701773

	RSK2 Protein, Human RPS6KA3; Ribosomal protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; Ribosomal S6 kinase 2; RSK-2; pp90RSK2	Human	E. coli
	RSK2 is a kinase downstream of ERK signaling and plays a critical role in mediating mitosis and stress responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK2 Protein, Human is the recombinant human-derived RSK2 protein, expressed by E. coli , with tag free.

HY-P76011

	RSK3 Protein, Human (sf9, GST) Ribosomal protein S6 kinase alpha-2; S6K-alpha-2; p90-RSK 2; RSK-3; RPS6KA2; MAPKAPK1C	Human	Sf9 insect cells
	RSK3, a kinase downstream of ERK signaling, crucially mediates mitogenic and stress-induced transcription factor activation. It regulates translation, impacting proliferation, survival, and differentiation. In epithelial ovarian cancer cells, RSK3 may act as a tumor suppressor, highlighting its diverse roles in cellular homeostasis and potential implications in cancer biology. RSK3 Protein, Human (sf9, GST) is the recombinant human-derived RSK3 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P701774

	RSK2 Protein, Human (His) RPS6KA3; Ribosomal protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; Ribosomal S6 kinase 2; RSK-2; pp90RSK2	Human	E. coli
	RSK2 is a kinase downstream of ERK signaling and plays a critical role in mediating mitosis and stress responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK2 Protein, Human (His) is the recombinant human-derived RSK2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701771

	RSK1 Protein, Human (sf9) RPS6KA1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; Ribosomal S6 kinase 1; RSK-1	Human	Sf9 insect cells
	RSK1 is a kinase downstream of ERK signaling and is critical for mitosis and stress-induced responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK1 Protein, Human (sf9) is the recombinant human-derived RSK1 protein, expressed by sf9 insect cells , with tag free.

HY-P701772

	RSK1 Protein, Human (sf9, His) RPS6KA1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; Ribosomal S6 kinase 1; RSK-1	Human	Sf9 insect cells
	RSK1 is a kinase downstream of ERK signaling and is critical for mitosis and stress-induced responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK1 Protein, Human (sf9, His) is the recombinant human-derived RSK1 protein, expressed by sf9 insect cells , with N-8*His labeled tag.

HY-P702651

	RPS6KA6 Protein, Human (sf9, GST) RPS6KA6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; ribosomal protein S6 kinase, 90kD, polypeptide 6; ribosomal protein S6 kinase alpha-6; RSK4; RSK-4; p90RSK6; p90-RSK 6; S6K-alpha 6; S6K-alpha-6; ribosomal S6 kinase 4; 90 kDa ribosomal protein S6 kinase 6; PP90RSK4	Human	Sf9 insect cells
	RSK4 (ribosomal S6 kinase 4) is a serine/threonine protein kinase that is constitutively active and does not require the presence of growth factors to function. It is involved in cell signaling pathways related to cell growth arrest, especially those mediated by p53/TP53 proteins. RPS6KA6 Protein, Human (sf9, GST) is the recombinant human-derived RPS6KA6, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P702650

	RPS6KA4 Protein, Human (sf9, His, GST) RPS6KA4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; ribosomal protein S6 kinase, 90kD, polypeptide 4; ribosomal protein S6 kinase alpha-4; MSK2; RSK B; RSKB; S6K-alpha-4; ribosomal protein kinase B; ribosomal protein S6 kinase alpha 4; 90 kDa ribosomal protein S6 kinase 4; mitogen- and stress-activated protein kinase 2; nuclear mitogen- and stress-activated protein kinase 2; RSK-B	Human	Sf9 insect cells
	RPS6KA4 Protein, Human (sf9, His, GST) is the recombinant human-derived RPS6KA4, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. ,

HY-P701819

	MSK1 Protein, Human (sf9, GST) RPS6KA5; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL	Human	Sf9 insect cells
	MSK1 is a serine/threonine protein kinase that centralizes multiple cellular processes by phosphorylating key transcription factors. In response to stimuli such as UV-C irradiation, EGF, and anisomycin, MSK1 activates CREB1 and ATF1, affecting gene expression through histone phosphorylation. MSK1 Protein, Human (sf9, GST) is the recombinant human-derived MSK1 protein, expressed by sf9 insect cells , with N-GST labeled tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80315

	RSK1 p90 Antibody (YA088)	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
	RSK1 p90 Antibody (YA088) is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to RSK1 p90. It can be used for WB,ICC,IHC-P,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P80887

	RSK3 Antibody (YA087) RPS6KA2; MAPKAPK1C; RSK3; Ribosomal protein S6 kinase alpha-2; S6K-alpha-2; 90 kDa ribosomal protein S6 kinase 2; p90-RSK 2; p90RSK2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Ri	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Hamster
	RSK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to RSK3. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Hamster.

HY-P80848

	*Phospho-RSK1 p90 (Ser380) Antibody (YA158)* RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP	WB, ICC/IF, IP	Human, Rat, Mouse
	Phospho-RSK1 p90 (Ser380) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Phospho-RSK1 p90 (Ser380). It can be used for WB, ICC/IF, IP assays with tag free, in the background of Human, Mouse and Rat.

HY-P80849

	*Phospho-RSK1 p90 (Thr359/Ser363) Antibody (YA157)* RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP	WB, IP	Human, Mouse, Rat
	Phospho-RSK1 p90 (Thr359/Ser363) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Phospho-RSK1 p90 (Thr359/Ser363). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P86159

	RSK2 Antibody (YA5851) Ribosomal protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; Ribosomal S6 kinase 2; RSK-2; pp90RSK2;	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	RSK2 Antibody (YA5851) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RSK2. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P85356

	RSK2 Antibody (YA5048) RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated	WB, ICC/IF, FC, ELISA	Human
	RSK2 Antibody (YA5048) is a mouse-derived and non-conjugated monoclonal antibody, targeting to RSK2. It can be applicated for WB, ICC/IF, FC, ELISA assays, in the background of human.

HY-P80886

	RSK1 p90 Antibody (YA676) RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP	WB, IP	Human, Mouse, Monkey
	RSK1 p90 Antibody (YA676) is a non-conjugated and Mouse origined monoclonal antibody about 83 kDa, targeting to RSK1 p90 (6B9). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Monkey.

HY-P80851

	*Phospho-RSK4 (Ser232) Antibody (YA155)* RPS6KA6; RSK4; Ribosomal protein S6 kinase alpha-6; S6K-alpha-6; 90 kDa ribosomal protein S6 kinase 6; p90-RSK 6; p90RSK6; Ribosomal S6 kinase 4; RSK-4; pp90RSK4	WB, ICC/IF	Human
	Phospho-RSK4 (Ser232) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 84 kDa, targeting to Phospho-RSK4 (Ser232). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P80850

	*Phospho-RSK2 (Ser227) Antibody (YA156)* RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated	WB, IP	Human, Mouse, Rat
	Phospho-RSK2 (Ser227) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 84 kDa, targeting to Phospho-RSK2 (Ser227). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P86213

	p90RSK Antibody (YA5905) RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	p90RSK Antibody (YA5905) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p90RSK. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P86364

	Phospho-p90RSK(Ser380) Antibody (YA6056) RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-p90RSK(Ser380) Antibody (YA6056) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to phosphorylated p90RSK (Ser380). It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P86403

	Phospho-p90RSK(Thr359/Ser363) Antibody (YA6095) RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-p90RSK(Thr359/Ser363) Antibody (YA6095) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to phosphorylated p90RSK (Thr359/Ser363). It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P80835

	Phospho-MSK1 (Ser360) Antibody (YA173) RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL	WB, ICC/IF, IP	Human, Mouse, Rat, Hamster
	Phospho-MSK1 (Ser360) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 90 kDa, targeting to Phospho-MSK1 (Ser360). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.

HY-P80836

	Phospho-MSK1 (Ser376) Antibody (YA172) RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL	WB, IHC-P, IP	Human, Rat
	Phospho-MSK1 (Ser376) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 90 kDa, targeting to Phospho-MSK1 (Ser376). It can be used for WB,IHC-P,IP assays with tag free, in the background of Human, Rat.

HY-P86551

	Phospho-MSK1(Ser360) Antibody (YA6243) RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-MSK1(Ser360) Antibody (YA6243) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to phosphorylated MSK1 (Ser360). It can be applicated for WB, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.