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Results for "

Protecting group

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) ADC Cytotoxin (2) ADC Linker (22) Amino Acid Derivatives (61) Apoptosis (10) Autophagy (9) Bacterial (1) Biochemical Assay Reagents (100) DNA/RNA Synthesis (3) Drug Intermediate (4) Drug-Linker Conjugates for ADC (1) E3 Ligase Ligand-Linker Conjugates (14) Endogenous Metabolite (1) Fluorescent Dye (2) HDAC (1) HSP (1) Integrin (1) Isotope-Labeled Compounds (6) Ligands for E3 Ligase (2) Liposome (4) mGluR (1) Microtubule/Tubulin (3) Monocarboxylate Transporter (1) NF-κB (1) NO Synthase (1) Nucleoside Antimetabolite/Analog (1) Potassium Channel (1) PROTAC Linkers (17) Radionuclide-Drug Conjugates (RDCs) (2)
By Research Areas:	Cancer (53) Cardiovascular Disease (1) Endocrinology (1) Infection (1) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (4)
Click Chemistry:	ADC Synthesis (2) Azide (9) Alkynes (4)
Oligonucleotides:	Nucleosides and their Analogs (4) T (1) Pegylated Lipids (4) U (1) G (2)

243

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Targets Recommended: HMG Family

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W048673

Fmoc-Phe(4-CONH2)-OH	Amino Acid Derivatives	Others
Boc-Dap(Boc)-OH is an amino acid derivative with a Boc protecting group and can be used in the synthesis of primary amides .

HY-W005561

H-Dab(Boc)-OMe hydrochloride	Amino Acid Derivatives	Others
H-Dab(Boc)-OMe hydrochloride is an N-terminally protected diaminobutyric acid containing two protecting groups: methoxy (OMe) and tert-butyloxycarbonyl (Boc). H-Dab(Boc)-OMe hydrochloride can be used to synthesize the bifunctional chelator H3Dpaa that can rapidly complex ⁶⁸Ga under physiological conditions .

HY-W013154

Fmoc-Tic-OH	Amino Acid Derivatives	Others
Fmoc-Tic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as the biotinylated derivative of the opioid receptor antagonist TIPP .

HY-W046355

Fmoc-D-Dap(Boc)-OH	Radionuclide-Drug Conjugates (RDCs) Amino Acid Derivatives	Others
Fmoc-D-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as DOTA-modified peptides and their metal chelates with cancer diagnostic effects .

HY-W048722

Fmoc-D-Thi-OH Fmoc-D-2-Thienylalanine	Amino Acid Derivatives	Others
Fmoc-D-Thi-OH (Fmoc-D-2-Thienylalanine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize AS-Z-P with thrombin inhibitory activity .

HY-W047799

Boc-Dap(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-Phe(4-CONH2)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a small-sized HTLV-I protease inhibitor with hydrophilicity .

HY-W048730

Fmoc-Phe(4-tBu)-OH	Amino Acid Derivatives	Others
Fmoc-Phe(4-tBu)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize rOicPaPhe(p-Me)-NH(2) with platelet aggregation activation inhibitory activity .

HY-W013153

Fmoc-D-Tic-OH	Amino Acid Derivatives	Others
Fmoc-D-Tic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg ¹⁰]HOE 140, which has bradykinin B1 antagonist activity .

HY-W048718

Fmoc-D-Tle-OH Fmoc-D-α-t-butylglycine	Amino Acid Derivatives	Others
Fmoc-D-Tle-OH (Fmoc-D-α-t-butylglycine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize chelating agents that can form a single stereoisomer-enriched form after coordination with metal centers .

HY-W048739

Fmoc-α-Me-Leu-OH	Amino Acid Derivatives	Others
Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity .

HY-W008919

Boc-Lys(Boc)-Onp N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester	Amino Acid Derivatives	Others
Boc-Lys(Boc)-Onp (N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester) is a lysine with a Boc protecting group. Boc-Lys(Boc)-Onp was used as a substrate for a catalyst model to study its enzymatic hydrolysis reaction catalyzed by a copper(II) complex .

HY-W097054

Fmoc-L-cysteic acid	Amino Acid Derivatives	Others
Fmoc-L-cysteic acid is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize triarylsulfonium compounds for radiolabeling of peptides .

HY-W019032

Fmoc-D-Dab(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity .

HY-W011156

Mpa(Trt)	Amino Acid Derivatives	Others
Mpa(Trt) is a 3-mercaptopropionic acid derivative containing a trityl protecting group (Trt) and can be used to synthesize compounds with anti-leukemia activity .

HY-78927

N-Boc-L-Prolinal	Amino Acid Derivatives	Others
N-Boc-L-Prolinal is a proline with a Boc protecting group, which can be used to synthesize biologically active peptide mimetics, such as the synthesis of Dolastatin 10 (HY-15580) analogs with anti-colon cancer activity .

HY-W008876

Fmoc-Pen(Trt)-OH	Amino Acid Derivatives	Others
Fmoc-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize the inhibitory cystine knot (ICK) peptide ProTx-II .

HY-W010922

Fmoc-Dap(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists .

HY-W047788

H-Dab(Boc)-OH	Amino Acid Derivatives	Others
H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities .

HY-W106325

Fmoc-N-Me-D-Trp(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-N-Me-D-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize somatostatin-dopamine chimeric analogs .

HY-W077219

Boc-L-Arg(Mtr)-OH Boc-Arg(Mtr)-OH	Amino Acid Derivatives	Others
Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .

HY-W548477

H-Lys(Fmoc)-OH hydrochloride	Amino Acid Derivatives	Others
H-Lys(Fmoc)-OH hydrochloride is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize diacylated GLP-1 derivatives with antidiabetic activity .

HY-W101889

Boc-Gln(Xan)-OH N-Boc-N'-xanthyl-L-glutamine	Amino Acid Derivatives	Others
Boc-Gln(Xan)-OH (N-Boc-N'-xanthyl-L-glutamine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antigenic activity .

HY-W091365

Boc-Asn(Xan)-OH N-Boc-N'-xanthyl-L-asparagine	Amino Acid Derivatives	Others
Boc-Asn(Xan)-OH (N-Boc-N'-xanthyl-L-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize locust fat growth hormone .

HY-W101305

Fmoc-Pen(Acm)-OH	Amino Acid Derivatives	Others
Fmoc-Pen(Acm)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize chemically modified cyclic peptides containing cell adhesion recognition (CAR) sequences .

HY-137002

Fmoc-N-Me-Arg(Pbf)-OH	Amino Acid Derivatives	Others
Fmoc-N-Me-Arg(Pbf)-OH is an amino acid derivative containing a guanidinium protecting group on the arginine side chain. Fmoc-N-Me-Arg(Pbf)-OH is used in the synthesis of neurotensin-derived NTS1 ligands for PET imaging .

HY-W008064

Fmoc-Cit-OH Fmoc-L-Citrulline	Amino Acid Derivatives	Cancer
Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif .

HY-W015987

9-Fluorenylmethyl carbamate Fmoc-NH2	Biochemical Assay Reagents	Others
9-Fluorenylmethyl carbamate (Fmoc-NH2) is an amide compound with an Fmoc protecting group, which can be used as a photobase initiator to prepare organosilane-based proton exchange membranes .

HY-W101935

N-Boc-D-Arg hydrochloride N-Boc-D-arginine hydrochloride	Amino Acid Derivatives	Others
N-Boc-D-Arg hydrochloride (N-Boc-D-arginine hydrochloride) is an amino acid derivative with a Boc protecting group, which can be used to synthesize desmopressin with the effects of improving nocturia, urinary incontinence and enuresis .

HY-W048697

Fmoc-D-Pen(Trt)-OH	Amino Acid Derivatives	Others
Fmoc-D-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize analogs of cyclic lanthionine enkephalin, a δ-opioid receptor selective ligand .

HY-W009118

Fmoc-5-Ava-OH	Amino Acid Derivatives	Others
Fmoc-5-Ava-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize fatty acid-based dimeric peptides with PSD-95 inhibitory activity .

HY-W010835

Boc-D-Cys(Trt)-OH Boc-S-trityl-D-cysteine	Amino Acid Derivatives	Others
Boc-D-Cys(Trt)-OH (Boc-S-trityl-D-cysteine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize the bicyclic depsipeptide histone deacetylase inhibitor spirocysteine .

HY-W089230

Boc-His(Boc)-OH N,N'-Di-tert-butoxycarbonyl-L-histidine	Amino Acid Derivatives	Others
Boc-His(Boc)-OH (N,N'-Di-tert-butoxycarbonyl-L-histidine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize the dodecapeptide α-mating factor of Saccharomyces cerevisiae .

HY-W101495

Boc-Leu-OH hydrate N-Boc-L-leucine monohydrate	Amino Acid Derivatives	Others
Boc-Leu-OH hydrate (N-Boc-L-leucine monohydrate) is an amino acid derivative with a Boc protecting group, which can be used to synthesize L-prolyl-L-leucyl-glycinamide peptide, a peptide mimetic with dopamine receptor modulatory activity .

HY-W041989

Fmoc-Oic-OH	Amino Acid Derivatives	Others
Fmoc-Oic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg ¹⁰]HOE 140, which has bradykinin B1 antagonist activity .

HY-34738

Boc-β-Ala-ol 3-(Boc-amino)-1-propanol	Amino Acid Derivatives	Others
Boc-β-Ala-ol (3-(Boc-amino)-1-propanol) is an alanine derivative with a Boc protecting group at the N-terminus, which can be used to synthesize bioactive peptide mimics, such as Nα-Benzoyl-α-azaornithine phenyl ester, which has trypsin inhibitory activity .

HY-W089233

Boc-D-Glu-OtBu N-Boc-D-glutaMic acid 1-tert-butyl ester	Amino Acid Derivatives	Others
Boc-D-Glu-OtBu (N-Boc-D-glutaMic acid 1-tert-butyl ester) is an amino acid derivative with a Boc protecting group, which can be used to synthesize Adamant-1-yl tripeptide with immunostimulatory activity .

HY-W088100

Boc-N-gamma-trityl-D-asparagin N-Boc-N'-trityl-D-asparagine; Boc-D-Asn(Trt)-OH	Amino Acid Derivatives	Cancer
Boc-N-gamma-trityl-D-asparagin (N-Boc-N'-trityl-D-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize metastasis-inhibiting or tumor growth-inhibiting metastasis-inhibiting MS derivatives .

HY-W014692

Boc-D-2,3-diaminopropionic acid N-t-Boc-amino-D-alanine; Boc-D-Dap-OH	Amino Acid Derivatives	Others
Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize a potent NMDA receptor glycine site agonist with GluN2 subunit-specific activity .

HY-W044285

Fmoc-D-4-Aph(cBm)-OH	Amino Acid Derivatives	Others
Fmoc-D-4-Aph(cBm)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active peptide mimetics, such as Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P)-D4Aph/D4Amf(Q)-Leu-ILys-Pro-DAla-NH2 with gonadotropin-releasing hormone (GnRH) antagonist activity .

HY-Y1169

Fmoc-Asp(OtBu)-OH 4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH	Amino Acid Derivatives	Others
Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .

HY-78933

Fmoc-MMAE	Microtubule/Tubulin ADC Cytotoxin	Cancer
Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC .

HY-20841

Boc-(2S)-Gly-4-pyranoyl (S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid; Boc-4-Pyranoyl-Gly-OH	Amino Acid Derivatives	Others
Boc-(2S)-Gly-4-pyranoyl ((S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid) is an amino-terminally protected glycine derivative that can be used to synthesize dipeptidyl peptidase IV with antidiabetic activity .

HY-W190935

Tris(O-TBDMS)3	Biochemical Assay Reagents	Others
Tris (O-TBDMS)3 is a Tris linker with 3 TBDMS protecting groups. The TBDMS is an acid labile protecting group.

HY-W088805

Fmoc-NIP-OH Fmoc-3-carboxypiperidine	Amino Acid Derivatives	Others
Fmoc-NIP-OH (Fmoc-3-carboxypiperidine) is a Fmoc-protected amino acid derivative commonly used in peptide synthesis .

HY-W800684

Benzyloxy carbonyl-PEG4-NHS ester	Biochemical Assay Reagents	Others
Benzyloxy carbonyl-PEG4-NHS ester is a reagent with a benzyl protecting group and an NHS ester. The NHS ester reacts with primary amines (-NH2). The benzyl protecting group can be removed by hydrogenolysis.

HY-172719

Fmoc-PEG9-alcohol	Biochemical Assay Reagents	Others
Fmoc-PEG9-alcohol is a heterobifunctional PEG linker featuring a Fmoc-protected primary amine and an alcohol group. The hydroxy group is a versatile functionality while the Fmoc protecting group can be removed with base to reveal a primary amine.

HY-141253

N-Boc-Tris	Biochemical Assay Reagents	Others
N-Boc-Tris is a protective reagent. N-Boc-Tris can utilize the Boc protecting group to protect amino groups in fields such as organic synthesis and pharmaceutical research and development, thereby avoiding unnecessary side reactions.

HY-W591969

Benzyl (6-oxohexyl)carbamate	Biochemical Assay Reagents	Others
Benzyl (6-oxohexyl)carbamate is a linker containing an aldehyde group and a benzyl (Cbz) protecting group. The aldehyde can react with hydrazine or hydrazide to form a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.

HY-W800681

Benzyloxy carbonyl-PEG4-acid	Biochemical Assay Reagents	Others
Benzyloxy carbonyl-PEG4-acid is a linker with a benzyl protecting group and a carboxylic acid. The carboxylic acid can undergo reactions with primary amines with the help of activators (EDC or HATU). The benzyl protecting group can be removed via hydrogenolysis.

HY-W591971

5-((tert-Butoxycarbonyl)amino)pentyl 4-methylbenzenesulfonate	Biochemical Assay Reagents	Others
5-((tert-Butoxycarbonyl)amino)pentyl 4-methylbenzenesulfonate is a PEG linker containing a Boc protected amine and a tosyl group. The protected amine can be deprotected under mild acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Cat. No.	Product Name

HY-L007

Immunology/Inflammation Compound Library

6,513 compounds

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. Inflammation is also the body's attempt at self-protection to remove harmful stimuli and begin the healing process. It’s part of the body's immune response. The immune system recognizes damaged cells, irritants, and pathogens, and inflammation begins the healing process. Inflammatory abnormalities are a large group of disorders that underlie a vast variety of human diseases. The immune system is often involved with inflammatory disorders, demonstrated in both allergic reactions and some myopathies, with many immune system disorders resulting in abnormal inflammation.

MCE designs a unique collection of 6,513 compounds that are useful tool for Immunology/Inflammation research or autoimmune inflammatory diseases drug discovery.

Cat. No.	Product Name	Type

HY-D1244

CO probe 1

Fluorescent Dyes/Probes

CO probe 1 (probe 2) is a highly efficient fluorescent CO probe (Ex=493 nm) with an allyl ether reaction site. In the presence of PdCl₂, CO reduces Pd ²⁺ to Pd ⁰, triggering a Tsuji-Trost reaction that removes the allyl protecting group, releases fluorescein, and generates a significant fluorescence signal. CO probe 1 has high selectivity, rapid response (fluorescence enhancement of 150 times within 20 minutes), and low cytotoxicity, and can be used for real-time imaging of CO in living cells. CO probe 1 may be used to study pathological mechanisms involving CO signaling regulation, such as inflammation, vascular disease, or cancer .

HY-172717

TAMRA-PEG4-t-butyl ester	Fluorescent Dyes/Probes
TAMRA-PEG4-t-butyl ester is a TAMRA red-fluorescent dye linker, with excitation/emission maximum 553/575 nm, containing a t-butyl protected carboxyl group which can be deprotected under acidic conditions.

Cat. No.	Product Name	Type

HY-W009229

Boc-Glu(OtBu)-OH	Biochemical Assay Reagents
Boc-Glu(OtBu)-OH is a protected glutamic acid derivative with two protecting groups: Boc- and OTBu. Boc-Glu(OtBu)-OH can be used in the study of peptide compound synthesis .

HY-41074

N,O-Dimethylhydroxylamine hydrochloride	Biochemical Assay Reagents
N,O-Dimethylhydroxylamine hydrochloride as an anomeric protecting group for use in oligosaccharide synthesis .

HY-W013081

Fmoc-Gln(Trt)-OH	Biochemical Assay Reagents
Fmoc-Gln(Trt)-OH is a glutamine derivative containing amine protecting group Fmoc .

HY-W1049061E

Boc-NH-PEG-COOH (MW 1000)	Drug Delivery
Boc-NH-PEG-COOH (MW 1000) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one carboxyl group. Boc-NH-PEG-COOH (MW 1000) is an important cross-linker with PEG chains .

HY-W1049061D

Boc-NH-PEG-COOH (MW 40000)	Drug Delivery
Boc-NH-PEG-COOH (MW 40000) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one carboxyl group. Boc-NH-PEG-COOH (MW 40000) is an important cross-linker with PEG chains .

HY-W1049061B

Boc-NH-PEG-COOH (MW 10000)	Drug Delivery
Boc-NH-PEG-COOH (MW 10000) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one carboxyl group. Boc-NH-PEG-COOH (MW 10000) is an important cross-linker with PEG chains .

HY-W1049061

Boc-NH-PEG-COOH (MW 2000)	Drug Delivery
Boc-NH-PEG-COOH (MW 2000) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one carboxyl group. Boc-NH-PEG-COOH (MW 2000) is an important cross-linker with PEG chains .

HY-W1049061A

Boc-NH-PEG-COOH (MW 5000)	Drug Delivery
Boc-NH-PEG-COOH (MW 5000) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one carboxyl group. Boc-NH-PEG-COOH (MW 5000) is an important cross-linker with PEG chains .

HY-W1049061C

Boc-NH-PEG-COOH (MW 20000)	Drug Delivery
Boc-NH-PEG-COOH (MW 20000) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one carboxyl group. Boc-NH-PEG-COOH (MW 20000) is an important cross-linker with PEG chains .

HY-W1049061H

Boc-NH-PEG-COOH (MW 3400)	Drug Delivery
Boc-NH-PEG-COOH (MW 3400) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one carboxyl group. Boc-NH-PEG-COOH (MW 3400) is an important cross-linker with PEG chains .

HY-149449

Poly-L-γ-glutamic acid sodium	Biochemical Assay Reagents
Poly-L-γ-glutamic acid sodium is a high molecular weight polymer composed of glutamic acid linked by γ-amino and carboxyl groups to form peptide bonds. Poly-L-γ-glutamic acid sodium protects bacteria from bacteriophage infection. Poly-L-γ-glutamic acid sodium plays an important role as a carrier material in compound delivery systems .

HY-140232E

BOC-NH-PEG-NH2 (MW 10000) Boc-NH-PEG-Amine (MW 10000)	Drug Delivery
BOC-NH-PEG-NH2 (MW 10000) (Boc-NH-PEG-Amine (MW 10000)) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG-NH2 (MW 10000) is an important cross-linker with PEG chains .

HY-140232A

BOC-NH-PEG-NH2 (MW 1000) Boc-NH-PEG-Amine (MW 1000)	Drug Delivery
BOC-NH-PEG-NH2 (MW 1000) (Boc-NH-PEG-Amine (MW 1000)) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG-NH2 (MW 1000) is an important cross-linker with PEG chains .

HY-140232H

BOC-NH-PEG-NH2 (MW 20000) Boc-NH-PEG-Amine (MW 20000)	Drug Delivery
BOC-NH-PEG-NH2 (MW 20000) (Boc-NH-PEG-Amine (MW 20000)) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG-NH2 (MW 20000) is an important cross-linker with PEG chains .

HY-140232I

BOC-NH-PEG-NH2 (MW 40000) Boc-NH-PEG-Amine (MW 40000)	Drug Delivery
BOC-NH-PEG-NH2 (MW 40000) (Boc-NH-PEG-Amine (MW 40000)) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG-NH2 (MW 40000) is an important cross-linker with PEG chains .

HY-140232C

BOC-NH-PEG-NH2 (MW 3400)	Drug Delivery
BOC-NH-PEG-NH2 (MW 3400) (Boc-NH-PEG-Amine (MW 3400)) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG-NH2 (MW 3400) is an important cross-linker with PEG chains .

HY-140232D

BOC-NH-PEG-NH2 (MW 5000)	Drug Delivery
BOC-NH-PEG-NH2 (MW 5000) (Boc-NH-PEG-Amine (MW 5000)) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG-NH2 (MW 5000) is an important cross-linker with PEG chains .

HY-140232B

BOC-NH-PEG-NH2 (MW 2000)	Drug Delivery
BOC-NH-PEG-NH2 (MW 2000) (Boc-NH-PEG-Amine (MW 2000)) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG-NH2 (MW 2000) is an important cross-linker with PEG chains .

HY-79647

Fmoc-OSu

N-(Fmoc-oxy)succinimide

Biochemical Assay Reagents

Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

HY-135233

N-Succinimidyl-S-acetylthioacetate

SATA

Biochemical Assay Reagents

N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies .

HY-155887

DSPE-PEG-Amine, MW 3400 ammonium

DSPE-PEG-NH2, MW 3400 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 3400 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 3400 (ammonium) can be converted to aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155908

DSPE-PEG-Amine, MW 10000 ammonium

DSPE-PEG-NH2, MW 10000 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 10000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 10000 (ammonium) can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-W440823A

DSPE-PEG-Amine, MW 1000 ammonium

DSPE-PEG-NH2, MW 1000 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155907

DSPE-PEG-Amine, MW 5000 ammonium

DSPE-PEG-NH2, MW 5000 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-W145552

4-Methoxyphenyl 3-O-allyl-β-D-galactopyranoside

4-Methoxyphenyl 3-O-allyl-beta-D-galactopyranoside

Carbohydrates

4-Methoxyphenyl 3-O-Allyl-β-D-galactopyranoside is an organic compound belonging to the family of galactopyranosides. It is often used as a building block for the synthesis of more complex glycosides and glycoconjugates. 4-Methoxyphenyl 3-O-Allyl-β-D-galactopyranoside has various applications in biochemical research, especially in the study of carbohydrate metabolism and protein-carbohydrate interactions. This compound contains an allyl protecting group that can be selectively removed using palladium-catalyzed conditions to reveal hydroxyl functionality for further chemical modification.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7502

2-(Hydroxymethyl)anthraquinone	Quinones Structural Classification Classification of Application Fields Anthraquinones Source classification Other Diseases Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields	Others
2-(Hydroxymethyl)anthraquinone is used as a photoremovable protecting group (PRPG) to chemically cage sex pheromone (e.g. (Z)-11-hexadecen-1-ol (sex pheromone of Chilo infuscatellussnellen)) .

HY-B1142

Lipoamide 5+ Cited Publications (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	NO Synthase
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .

HY-Y1080

N-Acetyl-R-leucine N-Acetyl-D-leucine	Microorganisms Source classification	Amino Acid Derivatives Monocarboxylate Transporter
N-Acetyl-R-leucine is an amino-protecting group N-substituted chiral amino acid. N-Acetyl-R-leucine is a PepT1 and MCT1 inhibitor with IC₅₀ of 0.74 and 11 mM, respectively. N-Acetyl-R-leucine can be used for LysoTracker signaling studies .

Cat. No.	Product Name	Chemical Structure

HY-W724364

N,O-Dimethylhydroxylamine-d6 hydrochloride
N,O-Dimethylhydroxylamine-d_{6_{hydrochloride is a deuterium labeled N,O-Dimethylhydroxylamine hydrochloride (HY-41074). N,O-Dimethylhydroxylamine hydrochloride as an anomeric protecting group for use in oligosaccharide synthesis .}}

HY-W010712S1

Fmoc-His(Trt)-OH-15N3
Fmoc-His(Trt)-OH- ¹⁵N₃ is the ¹⁵N labeled Fmoc-His(Trt)-OH (HY-W010712). Fmoc-His (Trt)-OH is a histidine derivative. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .

HY-Y1636S1

Fmoc-Arg(Pbf)-OH-13C6
Fmoc-Arg(Pbf)-OH- ¹³C₆ is the ¹³C labeled Fmoc-Arg(Pbf)-OH . Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .

HY-W101495S

Boc-Leu-OH·H2O-13C
Boc-Leu-OH·H₂O- ¹³C is a ¹³C-labeled Boc-Leu-OH (HY-W101495). Boc-Leu-OH hydrate (N-Boc-L-leucine monohydrate) is an amino acid derivative with a Boc protecting group, which can be used to synthesize L-prolyl-L-leucyl-glycinamide peptide, a peptide mimetic with dopamine receptor modulatory activity .

HY-Y1169S1

Fmoc-Asp(OtBu)-OH-13C4,15N
Fmoc-Asp(OtBu)-OH- ¹³C₄, ¹⁵N is the ¹³C and ¹⁵N labeled Fmoc-Asp(OtBu)-OH . Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .

HY-Y1169S2

Fmoc-Asp(OtBu)-OH-d3
Fmoc-Asp(OtBu)-OH-d₃ (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d₃) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .

Cat. No.	Product Name		Classification

HY-151715

N3-D-Dap(Fmoc)-OH		Azide
N3-D-Dap(Fmoc)-OH is a click chemistry reagent. N3-D-Dap(Fmoc)-OH can be used as a component for coupling by click reaction and as an orthogonally protected diaminocarboxylic acid derivative . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W457953

tert-Butyl N-(4-azidobutyl)carbamate		Azide
tert-Butyl N-(4-azidobutyl)carbamate is N-Boc protected crosslinker. tert-Butyl N-(4-azidobutyl)carbamate can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

HY-151825

Fmoc-L-Phe(4-NH-Poc)-OH		Alkynes
Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry .

HY-151748

N3-L-Orn(Fmoc)-OH		Azide
N3-L-Orn(Fmoc)-OH is a Fmoc-protected ornithine derivative, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151703

Boc-D-Lys(N3)-OH		Azide
Boc-D-Lys(N3)-OH is a Boc-protected amino acid derivative, can be used as a click chemistry reagent and an intermediate for synthesis of linkers . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151824

Boc-L-Phe(4-NH-Poc)-OH		Alkynes
Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151764A

N3-D-Orn(Boc)-OH (CHA)		Azide ADC Synthesis
N3-D-Orn(Boc)-OH (CHA) is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151764

N3-D-Orn(Boc)-OH		Azide ADC Synthesis
N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151823

8-Azido-octanoyl-OSu		Azide
8-Azido-octanoyl-OSu is a click chemistry reagent containing an azide group. Used as a building block to introduce 8-azidooctanoic acid (CAS 217180-76-2) fragment. This fragment is used for further modifications using Click-chemistry (CuAAC), as a protected aminogroup or is used in physico-chemical investigations . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151640

Fmoc-DAP-N3		Azide
Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151687

Fmoc-L-Tyr(2-azidoethyl)-OH		Azide
Fmoc-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr(2-azidoethyl)-OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151837

H-L-Phe(4-NH-Poc)-OH hydrochloride		Alkynes
H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent containing an azide group. Used as a modified Phe or Tyr analogue in protein and peptide biosynthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-118783

2-Hexyl-4-pentynoic acid (±)-2-Hexyl-4-pentynoic acid		Alkynes
2-Hexyl-4-pentynoic acid ((±)-2-Hexyl-4-pentynoic acid), a Valproic acid (HY-10585) derivative, exhibits potential roles of HDAC inhibition (IC₅₀ = 13 μM) and HSP70 induction. 2-Hexyl-4-pentynoic acid causes histone hyperacetylation and protect against glutamate-induced excitotoxicity in cultured neurons. 2-Hexyl-4-pentynoic acid can be used for the study of breast carcinoma. 2-Hexyl-4-pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

Cat. No.	Product Name		Classification

HY-W440823A

DSPE-PEG-Amine, MW 1000 ammonium DSPE-PEG-NH2, MW 1000 ammonium		Pegylated Lipids
DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-164253

TBS-rG(Ac)		Nucleosides and their Analogs G
TBS-rG(Ac)Is with TBSProtecting Group (Protect OHHydroxyl), acetylated guanosine ribonucleotide.

HY-W425093

(S)-DMT-glycidol-T		Nucleosides and their Analogs T
(S)-DMT-glycidol-T is a Glycidol-Thymine complex with a dimethoxytrityl (DMT) protecting group.

HY-164249

DMT-rG(Ac)		Nucleosides and their Analogs G
DMT-rG(Ac)Is with DMTProtecting Group (Protect 5'end), acetylated guanosine ribonucleotide.

HY-164252

DMT-2'-F-U 5′-O-Trityl-2′-deoxy-2′-fluorouridine		Nucleosides and their Analogs U
DMT-2'-FU (5'-O-Trityl-2'-deoxy-2'-fluorouridine)Is with DMTProtecting Group (Protect 5'end), FLabeled uridine ribonucleotide.

HY-155887

DSPE-PEG-Amine, MW 3400 ammonium DSPE-PEG-NH2, MW 3400 ammonium		Pegylated Lipids
DSPE-PEG-Amine, MW 3400 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 3400 (ammonium) can be converted to aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155908

DSPE-PEG-Amine, MW 10000 ammonium DSPE-PEG-NH2, MW 10000 ammonium		Pegylated Lipids
DSPE-PEG-Amine, MW 10000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 10000 (ammonium) can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155907

DSPE-PEG-Amine, MW 5000 ammonium DSPE-PEG-NH2, MW 5000 ammonium		Pegylated Lipids
DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

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