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  3. Fmoc-Cit-PAB-OH

Fmoc-Cit-PAB-OH is a peptide linker containing an Fmoc-protected amine and citrulline residue. The Fmoc group can be deprotected under basic conditions to obtain the free amine, which can be used for further conjugations.

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Fmoc-Cit-PAB-OH Chemical Structure

Fmoc-Cit-PAB-OH Chemical Structure

CAS No. : 870487-04-0

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Description

Fmoc-Cit-PAB-OH is a peptide linker containing an Fmoc-protected amine and citrulline residue. The Fmoc group can be deprotected under basic conditions to obtain the free amine, which can be used for further conjugations.

Molecular Weight

502.56

Formula

C28H30N4O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C(OC(N[C@H](C(NC1=CC=C(CO)C=C1)=O)CCCNC(N)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 70 mg/mL (139.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9898 mL 9.9491 mL 19.8981 mL
5 mM 0.3980 mL 1.9898 mL 3.9796 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9898 mL 9.9491 mL 19.8981 mL 49.7453 mL
5 mM 0.3980 mL 1.9898 mL 3.9796 mL 9.9491 mL
10 mM 0.1990 mL 0.9949 mL 1.9898 mL 4.9745 mL
15 mM 0.1327 mL 0.6633 mL 1.3265 mL 3.3164 mL
20 mM 0.0995 mL 0.4975 mL 0.9949 mL 2.4873 mL
25 mM 0.0796 mL 0.3980 mL 0.7959 mL 1.9898 mL
30 mM 0.0663 mL 0.3316 mL 0.6633 mL 1.6582 mL
40 mM 0.0497 mL 0.2487 mL 0.4975 mL 1.2436 mL
50 mM 0.0398 mL 0.1990 mL 0.3980 mL 0.9949 mL
60 mM 0.0332 mL 0.1658 mL 0.3316 mL 0.8291 mL
80 mM 0.0249 mL 0.1244 mL 0.2487 mL 0.6218 mL
100 mM 0.0199 mL 0.0995 mL 0.1990 mL 0.4975 mL
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Fmoc-Cit-PAB-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Fmoc-Cit-PAB-OH
Cat. No.:
HY-W141765
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