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Perfluoroundecanoic acid

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W142432
    Perfluoroundecanoic acid

    		Biochemical Assay Reagents β-catenin Wnt Arginase TGF-beta/Smad mTOR Akt ERK Atg8/LC3 p62 Autophagy Metabolic Disease Inflammation/Immunology Cancer
    Perfluoroundecanoic acid is a perfluoroalkyl substance (PFAS). Perfluoroundecanoic acid is an orally active oxidative stress inducer. Perfluoroundecanoic acid promotes macrophage M2 polarization, activates Wnt/β-catenin signaling and enhances β-catenin nuclear accumulation. Perfluoroundecanoic acid -induced M2 phenotype macrophage accelerates tumor progression in vitro and in vivo. Perfluoroundecanoic acid induces DNA damage, reproductive and pathophysiological dysfunctions via oxidative stress in male Swiss mice. Perfluoroundecanoic acid inhibits Leydig cell development in pubertal male rats via inducing oxidative stress and autophagy. Perfluoroundecanoic acid accelerates insulitis development in a mouse model of type 1 diabetes. Perfluoroundecanoic acid can be used for the study of ovarian cancer, type 1 diabetes and inflammation .
    Perfluoroundecanoic acid
  • HY-W142432R
    Perfluoroundecanoic acid (Standard)

    		Reference Standards Biochemical Assay Reagents Others
    Perfluoroundecanoic acid (Standard) is the analytical standard of Perfluoroundecanoic acid. This product is intended for research and analytical applications. Perfluoroundecanoic acid is an orally active inducer of oxidative stress and DNA damage. Perfluoroundecanoic acid exhibits genotoxicity and reproductive toxicity in swiss mice. Perfluoroundecanoic acid is utilized as a processing aid in the manufacture of fluoropolymer for its thermal and pressure stability, and properties of having both water-repellent and oil-repellent groups and hydrophilic groups on the same molecule .
    Perfluoroundecanoic acid (Standard)

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