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Pacritinib-d<sub>4</sub>

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16379S
    Pacritinib-d4

    SB1518-d<sub>4sub>

    		 Isotope-Labeled Compounds JAK FLT3 Cancer
    Pacritinib-d8 (SB1518-d8) is the deuterium labeled Pacritinib (HY-16379). Pacritinib (SB1518) is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2 V617F mutant (IC50=19 nM). Pacritinib also inhibits FLT3 (IC50=22 nM) and its mutant FLT3 D835Y (IC50=6 nM).
    Pacritinib-d4

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