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PFI-7

" in MedChemExpress (MCE) Product Catalog:

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1

Fluorescent Dye

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D2259
    PFI-7

    		E1/E2/E3 Enzyme Others
    PFI-7 is a probe, which binds to human GID4 (KD is 79 nM), and antagonizes the binding of Pro/N-degrons. PFI-7 can be utilized in C-terminal to LisH (CTLH) complex research and development of targeted protein degradation .
    PFI-7
  • HY-174997
    PFI-7-O-C4-piperazin

    		E3 Ligase Ligand-Linker Conjugates Cancer
    PFI-7-O-C4-piperazin is a E3 ligase ligand-linker conjugate that can be used for synthesis of PROTACs, such as NEP162 (HY-174996). The E3 ligase ligand (PFI-7) of NEP162 is a highly selective antagonist of GID4 (KD = 0.22 μM). NEP162 is a BRD4 PROTAC degrader with anti-tumor activity [1] .
    PFI-7-O-C4-piperazin

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